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Journal : International Islamic Medical Journal

The Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate) Noviana, Dian; Syarifah, Mustika Chasanatusy; Gumilang, Retna; Bintarti, Tri Wahyuni
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4445

Abstract

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax. Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate). Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa. Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05. Conclusion: Statistically it can be concluded that there is no effect of  the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Correlation Between Workload and Burnout of Educational Staff Faculty of Medicine Universitas Nahdlatul Ulama Surabaya Azizah AS, Nur; Puspitarini, Marinda Dwi; Gumilang, Retna; Farikhah, Zumrotul; Nafisah, Irma Binti Roudlotul; Bariyah, Khadijah Khairul
Jurnal Medis Islam Internasional Vol 7 No 1 (2025): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i1.6489

Abstract

Introduction: High workload among educational staff may adversely impact mental health, leading to stress, fatigue, and anxiety. In academic settings, particularly in medical faculties, complex task demands often result in psychological pressure. This study is essential to understand whether workload influences the mental health of educational staff at the Faculty of Medicine Universitas Nahdlatul Ulama Surabaya (FK UNUSA). Objective: This study aims to analyze the relationship between workload and mental health (burnout) among educational staff at the FK UNUSA. Methods: This quantitative study employed a survey approach. Data were collected using standardized questionnaires measuring two main variables: workload (NASA-TLX) and burnout (Maslach Burnout Inventory). A total of 21 educational staff members participated. Statistical analysis was conducted using the Spearman Rank correlation test to examine the relationship between the two variables. Results: The findings indicate a significant correlation between workload and mental health (p = 0.016). Educational staff with higher workloads tended to experience burnout. However, at the FK UNUSA, most educational staff reported mild to moderate workloads, while their mental health conditions were generally categorized as low to moderate burnout. Conclusions: A significant relationship exists between workload and burnout among educational staff at the FK UNUSA (p-value = 0.016). Although workload is an important factor, it does not act alone. Other contributing factors, such as social support, emotional stress, and work environment, also play critical roles in determining burnout levels.