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Testing Of The Nephroprotective Effectiveness Of Sail Leaf (Syzygium Polyanthum (Wight.)Walp.) In DoxorubisinInduced Male Wistar Rat Dewi; Ali Nafiah Nasution; Ermi Girsang
International Journal of Science, Technology & Management Vol. 2 No. 6 (2021): November 2021
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v2i6.372

Abstract

Cancer is one of the leading noncommunicable diseases leading to death worldwide. Cancer treatment has progressed but has side effects including nephrotoxic effects. The toxicity of doksorubisin has been widely known which is likely to be chained by the metabolic conversion of doxorubicin to doxorubicinol. The main mechanism of doxorubicinol toxicity occurs due to its interaction with iron and the formation of ROS that damages cell macromolecules. One of the plants that are widely used by the community to deal with various diseases and prevention is bay leaves. Bay leaves contain secondary metabolites that are antioxidant in nature. Antioxidants are needed to protect the body's cells from oxidative damage, preventing various degenerative diseases such as cancer, cardiovascular disease. The study aimed to determine the content of nephroprotective EEDS chemical compounds in phytochemical screening, EEDS characterization and EEDS nephroprotective activity in doxorubicin-induced mice based on uric acid, ureum and creatine levels. The study was experimentally laboratory using mice as test animals. The treatment group consisted of CMC-Na 0.5%, Nature E, EEDS doses of 100 mg/kgBB, 300 mg/kgBB and 500 mg/kgBB followed by administration of doxorubicin. The results showed phytochemicalally EEDS contains chemical compounds that are nephroprotective namely flavonoids, steroids / triterpenoids, saponins . EEDS has a water soluble sari content value of 21.64%, total ash content of 1.79%, water content of 9.98%. Ethanol soluble juice levels were 45.38% and acid insoluble ash levels were 0.39%. EEDS doses of 100 mg/kgBB, 300 mg/kgBB and 500 mg/kgBB can lower uric acid, ureum and cretinine levels and can picture the histopathology of doxorubicin-induced mouse kidneys with an effective dose of 500 mg/kgBB. It can be concluded that ethanol extract of bay leaves has nephroprotective activity.
Pengaruh Pemberian Ekstrak Etanol Daun Kunyit (Curcuma Domestica Val) Terhadap Kadar Glukosa Darah Tikus Putih (Rattus Norvegicus) Jantan Yang Di Induksi Akmalul Habib Damanik; Asyrun Alkhairi Lubis; Ermi Girsang
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1682

Abstract

Indonesia is the largest archipelago in the world (17,504 islands). In addition, Indonesia has abundant natural resources and fertile soil that allows a wide variety of plants to live. Curcuma domestica val, known as turmeric, is one of Indonesia's medicinal plants. A number of active ingredients found in turmeric have been shown in studies to have potential health benefits, including anti-diabetic anti-inflammatory, anti-cancer, cough medicine, liver medicine, and Alzheimer's disease. Based on the results of phytochemical research, flavonoids, alkaloids, tannins, triterpenoids, steroids, saponins, and glycosides are present in the ethyl ethanol extract of turmeric leaves (Curcuma domestica Val). Diabetes mellitus is a metabolic condition characterised by increased blood glucose levels caused by disruption of the insulin hormone which functions to lower blood glucose levels to maintain body homeostasis. Because of the close relationship between diabetes mellitus and lifestyle, diet, sleep, work, daily routine activities and others must be balanced. This study was conducted in the laboratory and was experimental in nature using male white rats as research subjects. Rats were induced using Alloxan at a dose of 100 mg/kgBB. Rats were divided into 6 groups, each consisting of 5 rats. Group 1 is a normal group, Group 2 is a negative group only given aquadest and induced with Alloxan.
An Analysis Of Determinants Stunting Incidents In Toddlers At Mazo Puskesmas UPT, South Nias District Waoziduhu Ndruru; Ermi Girsang; Sri Lestari Ramadhani Nasution; Liani Br Ginting
Jurnal Scientia Vol. 13 No. 03 (2024): Education and Sosial science, June - August 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The problem of stunting is a disturbance in the growth of a child's height or body length, where the height growth does not match with increasing age, which is also an abnormal condition of the body caused by more than one factor (multifactor). So this re-search discusses many things, including analyzing the influence of clean water access, latrine access, hand washing behavior with soap (CTPS), history of exclusive breastfeed-ing and MP-ASI on the growth and development of toddlers aged 24-59 months. This research used a cross sectional study design. The research was conducted in March-April 2020. Respondents were 118 children under five (aged 24-59 months) who lived in Og-an Ilir. The selection of respondents was taken using a simple random sampling tech-nique. Stunting, a condition characterized by impaired growth and development in chil-dren due to poor nutrition, recurrent infections, and inadequate psychosocial stimulation, is a significant public health problem. Statistical analysis was carried out to identify cor-relations and potential causal relationships between these variables and the incidence of stunting. The results show that low socio-economic status and maternal education are significantly related to high stunting rates. Inadequate food intake and poor sanitation practices are also important factors. Frequent infections, especially gastrointestinal dis-eases, are known to worsen the risk of stunting in toddlers.The study concludes that a multifaceted approach is needed to address stunting, involving improved economic con-ditions, educational initiatives for mothers, improved nutrition programs, better access to health services, and improved sanitation facilities. These findings highlight the im-portance of integrated public health strategies to reduce stunting and improve the wel-fare of children in South Nias District. Further research is recommended to explore long-term interventions and their effectiveness in various settings.
Analisis Pengaruh Kelengkapan Pencatatan Rekam Medis Pada Patient Safety Goals Di RS Royal Prima Tahun 2024 Dirgantara, Oscar; Ermi Girsang; Nasution, Ali Napiah
Jurnal Ners Vol. 9 No. 1 (2025): JANUARI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i1.30835

Abstract

Tingkat kejadian kematian yang terjadi karena kesalahan medis telah meningkat secara signifikan selama 10 tahun terakhir. Salah satu kesalahan medis yang sering terabaikan adalah pencatatan rekan medis khususnya pada asesmen awal pasien. Pencatatan Rekam Medis yang lengkap yang baik adalah komponen penting dalam pengelolaan informasi kesehatan di Rumah Sakit. Mengidentifikasi apakah faktor kelengkapan pencatatan Rekam Medisdapat mempengaruhi pencapaian International Patient Safety Goals. Penelitian ini menggunakan penelitian survei yang bersifat analitik deskriptif dengan menggunakan desain cross sectional study. Sampel diambil dari Rekam Medis pasien rawat inap di Rumah Sakit Royal Prima Medan periode Januari 2024 yang berjumlah 218 pasien. Pada penelitian yang dilakukan di RS Royal Prima Medan pada periode Januari 2024, didapatkan hasil kelengkapan pencatatan Rekam Medis mencapai 82% dan standarisasi JCI 7th edition yang menggunakan IPSG di RS Royal Prima Medan pada periode Januari 2024 mencapai 84,17%. Dari penelitian ini dapat disimpulkan sementara bahwa semakin tinggi nilai pencatatan Rekam Medis, maka nilai IPSG juga akan meningkat pada faktor identifikasi pasien, komunikasi yang efektif, dan keamanan penggunaan obat.Kendati demikian, harus ada perubahan dalam penyusunan tujuan utama akreditasi JCI, karena tidak dapat diletakkan pada seluruh lapisan Rumah Sakit.
An Evaluation Of The Effectiveness Of Using The Self-Registration Station (ADM) Method At The Community Health Center, Batugana District North Padang Lawas S. Shelly Hazlina Hararap; Ermi Girsang; Sri Lestari Ramadhani Nasution; Liani Br Ginting
Jurnal Scientia Vol. 13 No. 04 (2024): Education and Sosial science, September-December 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Queues arise due to the need for services exceeding the capacity of services or service facilities so that users of facilities cannot immediately get services due to busy services. Very long queues and taking too long to get a turn for service are very dissatisfying for patients with the Self-Registration Kiosk (ADM) method at Batugana Health Center aims to maximize the outpatient registration process in order to create easy, fast and comfortable services for patients. However, in its implementation there are still many elderly people who do not understand its use and sometimes there are problems with the system, thus slowing down the service process at Batugana Health Center. The purpose of this study was to evaluate the effectiveness of the use of the Self-Registration Kiosk Method (ADM) at Batugana Health Center. The method in this study is qualitative analytic. The sample in this study consisted of 4 informants including: Head of the Health Center, Head of the Self-Registration Kiosk Division, Self-Registration Kiosk Officers and Outpatients. Data were obtained through in-depth interviews with informants, then the data was analyzed by data reduction through Data Triangulation and sources, then displayed in narrative form. The results of the study showed that there was an influence of human resources, SOPs and facilities and infrastructure on the use of the Self-Registration Kiosk (ADM) method at Batugana Health Center on the evaluation of the effectiveness of the use of the Self-Registration Kiosk (ADM) Method at Batugana Health Center., has not fully implemented the use of APM effectively because the expected results have not been in accordance, namely creating fast service. At Batugana Health Center, the efforts that will be made are to re-evaluate the performance of officers on APM, determine officers who really understand the APM machine. And what will be done is to create an SOP on the use of the APM machine, check the function of the APM machine, add internet quality and add electric generators.
E-Cigarettes and Gingival Pigmentation: A Public Health Concern Among Adolescents Ermi Girsang; Firdha Muharraran; Irfan Aulia
Archives of The Medicine and Case Reports Vol. 6 No. 2 (2025): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v6i2.691

Abstract

Electronic cigarette (e-cigarette) use has rapidly increased among adolescents, raising concerns about its impact on oral health. This study investigated the association between e-cigarette and gingival pigmentation among adolescents in a community setting. A cross-sectional study was conducted in November 2024 among members of the Vapers City of Medan community. Data were collected through a Google Form questionnaire and photographic documentation of participants' gingiva. The questionnaire assessed e-cigarette use patterns, including frequency and duration, and any concurrent use of conventional cigarettes. Gingival pigmentation was assessed through photographs, noting the presence and extent of pigmentation. Data were analyzed using SPSS, employing Chi-Square, correlation, and multivariable tests to determine the association between e-cigarettes and gingival pigmentation. E-cigarette use was significantly associated with gingival pigmentation (p=0.026). Adolescents who used e-cigarettes had a higher prevalence of gingival pigmentation compared to those who did not. Correlation analysis revealed a moderate positive correlation between e-cigarette use and gingival pigmentation severity (r=0.54, p=0.01). Duration and frequency of e-cigarette use were also weakly positively correlated with gingival pigmentation severity. Multivariable analysis confirmed that e-cigarette use (OR=4.5, 95% CI=1.2-16.8, p=0.024), duration of use (OR=2.1, 95% CI=1.1-4.0, p=0.028), and frequency of use (OR=1.8, 95% CI=1.0-3.2, p=0.046) were independently associated with gingival pigmentation. In conclusion, e-cigarette use is significantly associated with gingival pigmentation in adolescents. This finding underscores the potential adverse effects of e-cigarettes on oral health, highlighting a growing public health concern.
Analysis of Hospital Health Service Quality Towards Patient Loyal-ty Through Leadership Style at Tgk. Chik Ditiro Sigli Regional General Hospital Rakhmat Akbar Dinur; Ermi Girsang; Fioni Fioni
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 5 No. 1 (2025): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v5i1.158

Abstract

This study examines the relationship between Hospital Healthcare Service Quality (HCSQ) and patient loyalty at Tgk. Chik Ditiro Sigli Regional General Hospital, with a focus on the mediating role of patient satisfaction and the influence of leadership styles. Employing a qualitative approach, data were collected through in-depth interviews, focus group discussions, and document analysis to capture the perspectives of patients, healthcare professionals, and hospital administrators. The findings reveal that key dimensions of HCSQ—such as responsiveness, empathy, communication, and facility environment—significantly impact patient satisfaction, which in turn mediates patient loyalty. Leadership styles emphasizing collaboration, communication, and patient-centeredness were found to enhance service quality and foster stronger patient-hospital relationships. Conversely, authoritarian leadership styles or those lacking effective communication negatively affected both employee performance and patient perceptions. The study highlights the importance of empowering employees, fostering teamwork, investing in infrastructure, and prioritizing patient-centered care to improve service quality and loyalty. These findings provide actionable insights for hospital management to enhance organizational performance and build long-term trust with patients. Future research is recommended to explore these relationships quantitatively across diverse healthcare settings and examine the role of cultural factors in shaping patient expectations and loyalty behaviors.
Analysis of the Suitability of the Head Nurse's Leadership Style Mediated by Job Satisfaction and Organizational Commitment to Nurse Performance at Pidie Jaya Regional General Hospital Dian Melani; Ermi Girsang; Tan Suyono
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 5 No. 1 (2025): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v5i1.161

Abstract

This study examines the relationship between the leadership styles of nurse managers, job satisfaction, organizational commitment, and their combined influence on nurse performance in Pidie Jaya Regional General Hospital. Using a qualitative approach, the research explores how transformational and transactional leadership styles affect organizational outcomes through the mediating variables of job satisfaction and commitment. The findings contribute to understanding the dynamics of effective nursing leadership in improving healthcare delivery.
A COMPARATIVE STUDY OF PHYSIOTHERAPY OUTCOMES BETWEEN INFRARED-TENS COMBINATION AND PNF THERAPIES IN NPH PATIENTS Nasution, Sri Lestari Ramadhani; Ermi Girsang; Siti Aminah
Journal of Vocational Health Studies Vol. 8 No. 3 (2025): March 2025 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V8.I3.2025.191-199

Abstract

Background: The pain experienced by Nucleus Pulposus Herniation (NPH) patients can have an impact on productivity and may lead to disability. Therefore, non-pharmacological therapies can serve as alternatives in reducing pain levels for Grade I and Grade II NPH patients. Purpose: To compare the difference in effectiveness between Infrared-Transcutaneous Electrical Nerve Stimulation (IR-TENS) combination and Proprioceptive Neuromuscular Facilitation (PNF) therapies in reducing pain among NPH patients. Method: This research employed a quasi-experimental design with a two group before and after intervention conducted at the Physical Medicine and Rehabilitation Unit of Royal Prima Hospital in Medan. A total of 20 NPH patients were provided with interventions, consisting of a combination of IR and TENS therapies for 10 patients, and PNF therapy for the other 10 patients, administered eight times for one month. Pain measurement was conducted using a Visual Analogue Scale (VAS) questionnaire before and after the interventions. The statistical analysis employed an Independent Sample T test, with a significance level (α) set at 0.05. Result: There was a reduction in moderate and severe pain scales in both groups, and no subjects were experiencing severe pain anymore. However, the reduction in moderate pain scale was higher in the group receiving the combination of infrared and TENS therapies (80%) compared to the PNF therapy (70%). The Independent T test showed that there was no significant difference between the effectiveness of the combination of IR-TENS therapies and PNF therapy on pain in NPH patients (p-value = 0.075). Conclusion: Both groups of patients experienced a reduction in pain scale after the interventions, although there was no significant difference in the outcome between the two treatment groups. This implies that both therapies are equally effective in suppressing pain in NPH patients.
Analysis of Hospital Health Service Quality Towards Patient Loyal-ty Through Leadership Style at Tgk. Chik Ditiro Sigli Regional General Hospital Rakhmat Akbar Dinur; Ermi Girsang; Fioni Fioni
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 5 No. 1 (2025): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v5i1.158

Abstract

This study examines the relationship between Hospital Healthcare Service Quality (HCSQ) and patient loyalty at Tgk. Chik Ditiro Sigli Regional General Hospital, with a focus on the mediating role of patient satisfaction and the influence of leadership styles. Employing a qualitative approach, data were collected through in-depth interviews, focus group discussions, and document analysis to capture the perspectives of patients, healthcare professionals, and hospital administrators. The findings reveal that key dimensions of HCSQ—such as responsiveness, empathy, communication, and facility environment—significantly impact patient satisfaction, which in turn mediates patient loyalty. Leadership styles emphasizing collaboration, communication, and patient-centeredness were found to enhance service quality and foster stronger patient-hospital relationships. Conversely, authoritarian leadership styles or those lacking effective communication negatively affected both employee performance and patient perceptions. The study highlights the importance of empowering employees, fostering teamwork, investing in infrastructure, and prioritizing patient-centered care to improve service quality and loyalty. These findings provide actionable insights for hospital management to enhance organizational performance and build long-term trust with patients. Future research is recommended to explore these relationships quantitatively across diverse healthcare settings and examine the role of cultural factors in shaping patient expectations and loyalty behaviors.
Co-Authors Akmalul Habib Damanik Ali Nafiah Nasution Alvin Abrar Harahap Analita Khoironissa Anita Merry Cisca Arie - Vonikartika Ary Denggan Syahputra Lubis Asri Widiya Sitompul Asyrun Alkhairi Lubis Ayu Hasanah Panjaitan Benedictus Juve Bethania Nadi Ida Febrina Siagian Chiuman, Linda Clinton Antony Dennis Wijaya Depi Yunaspi Dewi DIAN MELANI Diana Agustina Ritonga Dirgantara, Oscar Disti Amanda Putri Djohan Djohan Dzil Fikri Erisman Hondro Eva Kristina Pelawi Fioni Fioni Firdha Muharraran Ginting, Chrismis Novalinda Gusbakti Gusbakti Hanjaya hardiansyah siregar Hariyento Halim Ibnu Rushd Ira Syaputri Irfan Aulia irza Haicha Pratama Jeri Yuliansyah Liani Br Ginting Liena M. Ridho Fitra Alamsya Maria Seri Arihta Marlinang I. Silalahi Martin Loodwyck Simanjuntak Maya Sari Mutia Maya Sari Mutiara Muhammad Agus Muljanto Muhammad Insan Andika Muhammad Nawal Hasya Nadia Zenni Andari Nasution, Ali Napiah Nasution, Sri Lestari Ramadhani Noni Rokaya Pasaribu Primanita Novi Andriati Putri Satriani Dachi Rakhmat Akbar Dinur Ramadhan Efendi Rapael Ginting Redo Widhio Mahatvavirya Ria Hartaty S. Shelly Hazlina Hararap Saprilliani . Sindy Zelvia SITI AMINAH Sri Lestari Nasution Sri Lestari Ramadhan Sri Lestari Ramadhani Sri Lestari Ramadhani Nasution Stefenie SURYANI Syaifullah Syaifullah Tan Suyono Tommy Adhi Wijaya Ulina Karo Karo Ulina Karo-karo Vijay Dhillon Waoziduhu Ndruru Welly Ria Utami Lubis Widya Pasca Amir Widyaningsih Oentari Widyaningsih Oentari Winda Tri Mutia Wiwin Dwi Handayani Wulan Dhari Yuliani Yuliani Zsa Zsa Ranty Bianca Saragih