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KEGIATAN PENYULUHAN KANDUNGAN BAKTERI PADA REMPAH-REMPAH YANG BEREDAR DIPASARAN Eriwaty Silalahi, Yosy Cinthya; Manurung, Kesaktian; Harefa, Karnerius
Jurnal Abdimas Mutiara Vol. 1 No. 2 (2020): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

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Rempah sekilas terlihat sama dengan bumbu. Namun faktanya kedua hal ini sangat berbeda. Rempah menurut berupa tumbuhan atau bagian tumbuhan yang bersifat aromatik dan berfungsi sebagai pemberi cita rasa pada makanan. Tumbuhan rempah menurut berupa bagianbagian tertentu dari tumbuhan yang digunakan sebagai bumbu, penguat cita rasa, pengharum, dan pengawet makanan yang penggunaannya terbatas. Rempah seringkali dikenal sebagai bumbu kering. Tujuan pengabdian masyarakat ini untuk memberikan penyuluhan dan informasi kandungan bakteri pada rempah-rempah yang beredar dipasaran. Hasil kegiatan pelaksanaan program pengabdian masyarakat tumbuhan rempah dan bumbu terdiri atas bermacam jenis. Tumbuhan rempah dan bumbu dapat berupa herba, rimpang, terna, bahkan pohon. Rempah dan bumbu erat penggunaanya dalam kehidupan sehari-hari, terutama untuk kegiatan memasak. Berdasarkan hasil kegiatan sosialisasi kandungan bakteri pada rempah-rempah yang beredar dipasaran. Maka dapat disimpulkan bahwa kegiatan ini membawa dampak dan pengaruh yang baik terhadap pengetahuan masyarakat dalam mengetahui kandungan bakteri pada rempah-rempah yang beredar dipasaran. Sehingga masyarakat dapat menjaga dan meningkatkan kesehatan.

SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIDIABETES DARI EKSTRAK ETANOL DAGING BUAH ALPUKAT (Persea americana Mill.) Simarmata, Yettrie; Manurung, Kesaktian; Harefa, Karnerius; Hasibuan, Mei Sri Rezeki
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Diabetes mellitus is a set of symptoms that arise in a person characterized by blood glucose levels exceeding normal (hyperglycemia) due to a lack of insulin in the body. One of the medicinal plants that can be used is avocado flesh. This study aims to determine the antidiabetic activity of avocado pulp extract (Persea americana Mill) against male white rats. This study used 25 male white rats divided into 5 groups, namely the negative control group CMC-Na 1%, the positive control group glibenclamide 0.45 mg/kg BW, the EEBA test group at doses of 50, 100, 200 mg/kg BW. The results of the one-way ANOVA analysis of the Tukey HSD test showed that the administration of EEBA at a dose of 100 mg/kg BW and EEBA at a dose of 200 mg/kg BW had a significant difference with a significance value of 0.024 and 0.026 and EEBA at a dose of 50 mg/kg BW had no significant difference with the significance 0.275. Based on the results of the study, it can be concluded that EEBA doses of 50, 100, 200 mg/kg BW have antidiabetic activity.

PERBANDINGAN UJI AKTIVITAS ANTI DIABETES EKSTRAK ETANOL BUAH PARE (Momordicacharantia L.) DAN DAUN LIDAH BUAYA (Aloe vera L.) PADA MENCIT JANTAN Sitompul, Erly; Supartiningsih, Supartiningsih; Harefa, Karnerius; Sari, Samsia Yolanda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Diabetes is a non-communicable degenerative disease that will increase in number in the future. This is evidenced by the increasing incidence of diabetes every decade. Bitter gourd and aloe vera are an alternative in treating Diabetes Mellitus because these plants contain saponins, flavonoids, and polyphenols (strong antioxidants), as well as glycosides cucurbitacin, momordicin, and charantin that can lower blood sugar, saponins, flavonoids, and alkaloids. This study aims to determine secondary metabolite compounds, anti-diabetic activity, and the combination of aloe vera extract and bitter melon extract that has antidiabetic activity. The method used in this study is an experimental method, namely testing the antidiabetic effect of extracts obtained from ethanol of bitter melon and aloe vera leaves on alloxan-induced mice. The results obtained from the research are that the administration of aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group with the ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW showed a very good effect on reducing BGD. This means that aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group given ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW had good antidiabetic activity.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KERSEN (Muntingia calabura L.) TERHADAP BAKTERI Staphylococcus aureus dan Methicillin-Resistant Staphylococcus aureus Maimunah, Siti; Harefa, Karnerius; Yuliana, Artha; Ritonga, Ahmad Hafizullah; Hulu, Arifin
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2757

Kersen (Muntingiacalabura L) is one of the wild plants that have medicinal properties. Cherry leaves contain flavonoid compounds, alkaloids, tannins, saponins, and steroids/triterpenoids. This study aims to determine the antibacterial activity of cherry leaf extract (Muntingiacalabura L) against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus. Dau cherry extract was prepared using the maceration method using 96% ethanol. The antibacterial activity was tested using the disc diffusion method. The results of the examination of the characteristics of the simplicia powder of cherry leaves obtained water content of 6.7%, water soluble extract content of 23.84%, marine ethanol content of 13.40%, total ash content of 1.61%, and acid insoluble ash content of 0.38%. Simplicia and cherry leaf extract contain flavonoids, alkaloids, tannins, sapomime, steroids/triterpenoids. Antibacterial activity test showed that cherry leaf extract (Muntingiacalabura L) inhibited the growth of Staphylococcus aureus at concentrations of 10% (13.7 mm), 20% (14.1 mm), 30% (15.0 mm), 40% (16, 0 mm), 50% (17.6 mm). Methicillin-Resistant Staphylococcus aureus bacteria at concentrations of extract 10% (13.5 mm), 20% (14.0 mm), 30% (14.8 mm), 40% (15.8 mm), 50% (17, 0mm). Cherry leaf extract has antibacterial activity against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus bacteria.

PENETAPAN ANGKA KAPANG KHAMIR (AKK) PADA REMPAH-REMPAH YANG DIJUAL DI PASAR SRI GUNTING MEDAN Maimunah, Siti; Harefa, Karnerius; Silalahi, Yosy Cinthya Eriwaty; Manurung, Kesaktian
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2761

Spices containing fungal contamination exceed the stipulated limit of 1x104 colonies/g which will affect the stability of the preparation and aflatoxins that are harmful to health such as liver cancer. This study aims to determine the value of the yeast mold number (AKK) in spices at the Sri Gunting market, Medan. The population in this study were spices in the form of wet powder, namely turmeric (Curcuma longa Linn.), ginger (Zingiber officinale Rosc.), and temulawak (Curcuma xanthorhiza Roxb.), and 250 grams of each ingredient was taken from four spice traders. with location criteria such as on the edge of a highway, near a ditch/gully, inside a kiosk, and near a meat seller as a sample. Subjects of research and observations are presented in the form of tables and figures which are then analyzed descriptively. The results of the study found that the AKK of spices sold at the Sri Gunting market in Medan was equal to trader A (turmeric 16.1x10^4, Ginger 7.9x10^4, Temulawak 11.1x10^4cfu/g), trader B (turmeric > 150, Ginger 11.5x10^4Temulawak 18x10^4cfu/g), merchant C (turmeric 12.2x10^4, Ginger 6.1x10^4, Temulawak 4.5x10^4cfu/g), and merchant D (turmeric >150, Ginger 10.9x10^4, Temulawak >150cfu/g) which means that the AKK contained from spices sold at the Sri Gunting market in Medan does not meet the requirements according to the Food and Drug Supervisory Agency (BPOM).

UJI AKTIVITAS BUAH OKRA(Abelmoschus esculentus L) TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA TIKUS Wiratma, Dicky Yuswardi; Manurung, Kesaktian; Harefa, Karnerius; Syaviera, Soraya
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2772

Diabetes mellitus is a metabolic disorder disease characterized by hyperglycemia. Abelmuschus esculentus or known as the okra plant, is often used as a treatment for DM because it has hypoglycemic and antioxidant effects. Okra (Abelmuschus esculentus) is believed by the public as one of the plants that can prevent and treat diabetes. This study aims to test whether the administration of okra fruit extract can reduce blood glucose levels in rats. The research subjects were 25 rats which were divided into 5 groups, which consisted of a negative control group with 1% NaCMC, a positive control group using glibenclamide and ethanol extract of okra fruit at a dose of 200 mg/kgBW, a dose of 250 mg/kgBW, a dose of 300 mg. /kgBB. Glucose levels were measured at T0, T1, T2, T3, T4 AND T5 using a test strip glucometer. This study was experimental.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEMANGI (Ocimumbasilicum L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcusaureus Manurung, Kesaktian; Marpaung, Jon Kenedy; Harefa, Karnerius; Mardianis, Mardianis
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2784

Basil (Ocimumbasilicum L.) is one of the natural plants that is easily obtained in Asia such as Indonesia which has medicinal properties. Basil leaves contain flavonoid compounds, tannins, saponins, and steroids/triterpenoids. These compounds are known to have antibacterial activity. This study aims to determine the antibacterial activity of the ethanolic extract of basil leaves (Ocimumbasilicum L.) against Staphylococcus aureus bacteria. This research is experimental. The test was carried out through several stages including material collection, preparation of simplicia, making ethanol extract of basil leaves, and testing the inhibitory power of basil leaves against Staphylococcus aureus bacteria. The ethanol extract of basil leaves was made by the maceration method using 96% ethanol and concentrated with a rotary evaporator to obtain a thick extract from basil leaves. Antibacterial activity was tested by the agar diffusion method using disc paper. The results of the antibacterial activity test showed that the ethanolic extract of basil leaves inhibited the growth of Staphylococcus aureus bacteria at concentrations of extracts of 5%, 10%, 15%, 20%, and 25% with inhibition zone diameters of 8. 31 mm, 9. 43 mm, respectively. 9. 73 mm, 9. 91 mm, and 11. 33 mm. The ethanol extract of basil leaves has antibacterial activity against Staphylococcus aureus bacteria.

FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN KINERJA BIDAN DALAM HUBUNGANNYA TERHADAP ANGKA KEMATIAN IBU DI KABUPATEN LABUHANBATU Simanjuntak, Friska Ernawati; Nababan, Donal; Harefa, Karnerius; Hakim, Lukman; Manurung, Jasmen
JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Vol 7, No 2 (2021): OKTOBER 2021
Publisher : Universitas Ubudiyah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33143/jhtm.v7i2.1730

ABSTRAKAngka Kematian Ibu (AKI) di Kabupaten Labuhanbatu masih cukup tinggi, terdapat 4 kasus kematian ibu dan 31 kematian bayi pada tahun 2020. Tenaga kesehatan merupakan sumber daya manusia dalam menjalankan pelayanan kesehatan di Puskesmas. Kinerja bidan merupakan faktor penting dalam mengurangi kasus angka kematian ibu di Kabupaten Labuhanbatu, beragam faktor yang mempengaruhi kinerja bidan adalah faktor usia, masa bekerja, pelatihan dan pengetahuan. Penelitian ini bertujuan untuk mengetahuai faktor-faktor yang berhubungan dengan kinerja bidan dalam hubungannya terhadap angka kematian ibu di Kabupaten Labuhanbatu. Desain penelitian menggunakan desain cross sectional study dengan metode kuantitatif, responden penelitian sebanyak 87 responden. Hasil analisis bivariat menunjukan variabel usia, pelatihan, dan pengetahuan berhubungan terhadap kinerja bidan ( P value < 0.05). Berdasarkan hasil analisis multivariat metode stepwise, variabel dominan yang berhubungan terhadap kinerja bidan dalam hubungannya terhadap angka kematian ibu di Kabupaten Labuhanbatu secara berurut adalah variabel pelatihan dengan nilai p value (sig) 0.009 < 0.05, OR 73.914, variabel pengetahuan dengan nilai p value (sig) 0.16 < 0.05, OR 47.053, dan variabel usia dengan nilai p value (sig) 0.039 < 0.05, OR 9.450. Disimpulkan bahwa variabel yang paling dominan berpengaruh terhadap kinerja bidan adalah variabel dengan nilai OR 73.914Kata kunci: Kinerja Bidan, Usia, Pelatihan, Masa Kerja, Pengetahuan, dan Angka Kematian Ibu

Ketidaklengkapan Pengisian Dokumen Clinical Pathway Kanker Paru (Studi Kualitatif di RSUP H.Adam Malik tahun 2021) Fajrinur, Fajrinur; Handini, Myrnawati Crie; Tarigan, Frida Lina; Harefa, Karnerius; Ginting, Daniel
JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Vol 8, No 1 (2022): APRIL 2022
Publisher : Universitas Ubudiyah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33143/jhtm.v8i1.2047

Abstrak Pelaksanaan clinical pathway (CP) pada pasien kanker paru akan menurunkan jumlah hari rawat inap pasien di rumah sakit. Penelitian bertujuan menggali lebih dalam ketidakkelengkapan pengisian dokumen clinical pathway (CP) kanker paru di RSUP H. Adam Malik tahun 2021. Metode penelitian adalah kualitatif dengan pendekatan fenomenologi di RSUP H. Adam Malik pada bulan Maret - September 2021. Informan penelitian diambil secara purposive sampling, sebanyak enam informan dengan kriteria pegawai yang terlibat didalam pembuatan, perencanaan, penyusunan dan pelaksanaan clinical pathway, memiliki masa kerja lebih dari dua tahun, mampu berkomunikasi dengan baik dan bersedia menjadi informan. Informan tersebut terdiri dari Kepala Bidang Pelayanan medik, Kepala Bidang Case Manager, Dokter bagian Paru, Kepala Perawat/perawat pelaksana bagian paru, Rekam Medik dan Tenaga Farmasi. Penelitian menggunakan metode analisis data Colaizzi. Penelitian menemukan empat hal penting dalam ketidaklengkapan pengisian clinical pathway kanker paru yaitu 1) Komunikasi: Sosialisasi clinical pathway kanker paru belum berjalan dengan optimal 2) Sumber daya: Sumber daya yang mengaudit pengisian clinical pathway belum tersedia khusus 3) Disposisi: Kurangnya komitmen dalam pengisian clinical pathway di rumah sakit 4) Struktur birokrasi: Struktur birokrasi yang mendukung pengisian clinical pathway. Kesimpulan penelitian adalah masih ditemukan lembaran clinical pathway tidak diisi secara lengkap. Disarankan untuk menyusun Standar Operasional Prosedur (SOP) khusus untuk pelaksanaan clinical pathway kanker paru untuk meningkatkan komitmen dalam pengisian clinical pathway kanker paru.Kata kunci: clinical pathway, kanker paru, rumah sakit, SOPÂ AbstractImplementation of clinical pathway (CP) in lung cancer patients will reduce the number of days of hospitalization for patients. This study aims to dig deeper into the incompleteness of filling out clinical pathway (CP) documents for lung cancer at H. Adam Malik Hospital in 2021. The research method was qualitative with a phenomenological approach at H. Adam Malik Hospital in March - September 2021. Research informants were taken by purposive sampling. , as many as six informants with the criteria of employees who are involved in the creation, planning, preparation and implementation of clinical pathways, have a working period of more than two years, are able to communicate well and are willing to become informants. The informants consisted of the Head of the Medical Services Division, the Head of the Case Manager Division, the Lung Doctor, the Chief Nurse/nurse implementing the Pulmonary Section, Medical Records and Pharmacy Staff. The study used the Colaizzi data analysis method. The study found four important things in the incomplete filling of lung cancer clinical pathways, namely 1) Communication: Socialization of lung cancer clinical pathways has not run optimally 2) Resources: Resources that audit clinical pathway filling are not specifically available 3) Disposition: Lack of commitment in filling clinical pathways pathways in hospitals 4) Bureaucratic structure: A bureaucratic structure that supports filling out clinical pathways. The conclusion of the study was that clinical pathway sheets were still not filled out completely. It is recommended to develop a special Standard Operating Procedure (SOP) for the implementation of lung cancer clinical pathways to increase commitment in filling lung cancer clinical pathways.Keywords: clinical pathway, lung cancer, hospital, SOP

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