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All Journal Jurnal Ilmu Kefarmasian Indonesia Edu Masda Journal Jurnal Farmasi dan Sains Indonesia (JFSI) KOLONI Pharmaceutical Science Journal Jurnal Sains Farmasi dan Kesehatan
Ayu Werawati
STIKes Widya Dharma Husada Tangerang
Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Edu Masda Journal

 1 
LITERATURE REVIEW : EVALUASI PELAYANAN INFORMASI OBAT DI INSTALASI FARMASI Ayu Werawati; Sayyidah Sayyidah; Gina Aulia; Fatwa Hikmatul Kurnia
Edu Masda Journal Vol 6, No 1 (2022): Edu Masda Journal Volume 6 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v6i1.145

Abstract

Quality is something that greatly affects customer satisfaction. Quality is the level of excellence of something, both goods and services. The level of consumersatisfaction can be measured from the comparison between consumer expectations with the reality felt by the consumer against an item or service. In health services, to be able to provide a quality health service, it must be started from the fulfillment of high ethical standards. Nowadays where there has been a shift in the orientation of pharmaceutical service management which prioritizes improving the quality of life of patients (patient oriented) rather than just selling drugs to patients (drug oriented), it is necessary for pharmacists to have an active role in carrying out their competencies so that drug use can be more optimal. It is also necessary to reduce drug-related problems. The lack of drug information provided can lead to a lack of patient understanding of the drug and can have a negative impact on the patient. The objective of this study was to identify the evaluation of drug information services against pharmaceutical service standards and drug information service guidelines. This research method is a literature review. The inclusion criteria used were Indonesian research with drug information services in pharmacy installations, articles published 2011-2021, full text articles. The result is that the evaluation of drug information services has met pharmaceutical service standards and meets drug information service guidelines.  ABSTRAKKualitas merupakan hal yang sangat mempengaruhi kepuasan konsumen. Kualitas merupakan tingkat keunggulan sesuatu, baik barang ataupun jasa, sehingga tingkat kepuasan konsumen dapat diukur dari perbandingan antara harapan dengan kenyatan yang didapat terhadap suatu barang atau jasa. Pada pelayanan kesehatan, untuk dapat memberikan suatu pelayanan kesehatan yang berkualitas harus dimulai dari pemenuhan standar etika yang tinggi. Di masa sekarang ini dimana telah terjadi pergeseran orientasi manajemen pelayanan kefarmasian yang mengutamakan peningkatan kualitas hidup pasien (patient oriented)  daripada sekedar memasarkan obat kepada pasien (drug oriented) menyebabkan perlunya peran aktif Apoteker untuk menjalankan kompetensi nya agar penggunaan obat dapat lebih optimal. Hal ini juga diperlukan untuk mengurangi masalah terkait obat. Kurangnya informasi obat yang diberikan dapat menyebabkan kurangnya pemahanan pasien akan obat dan dapat berdampak buruk pada pasien.  Penelitian ini bertujuan untuk mengidentifikasi evaluasi pelayanan informasi obat terhadap standar pelayanan kefarmasian dan pedoman  pelayanan informasi obat. Metode penelitian ini merupakan suatu Literature review. Kriteria inklusi yang digunakan adalah penelitian Indonesia dengan pelayanan informasi obat di instalasi farmasi, artikel diterbitkan 2011-2021, artikel full text. Hasil penelitian yang dihasilkan bahwa evaluasi pelayanan informasi obat  sudah memenuhi standar pelayanan kefarmasian dan  memenuhi pedoman  pelayanan informasi obat.
STUDI LITERATUR KHASIAT KOMBINASI EKSTRA HERBA PEGAGAN DAN EKSTRAK DAUN LIDAH BUAYA SEBAGAI ANTIAGING Dewi, Bheta Sari; Werawati, Ayu
Edu Masda Journal Vol 7, No 1 (2023): Edu Masda Journal Volume 7 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v7i1.182

Abstract

Traditional herbs have been used for thousands of years for medicinal and skin care purposes. Several types of old ingredients are known for their anti-aging properties, such as Centella asiatica L herb extract and Aloe vera L leaf extract. Both are known for their beneficial properties in maintaining healthy and beautiful skin, including antioxidant, anti-inflammatory and regenerative effects. This study aims to evaluate the efficacy of a combination of gotu kola herb extract and aloe vera herb extract as an antiaging herb. Therefore, the two extracts need to look for related references. This research method involved studying the literature from articles and scientific journals related to the efficacy of  Centella asiatica L herb extract and aloe vera leaf extract as antiaging. The data were analyzed and compiled in the form of a literature synthesis. The results of this study indicate that the combination of gotu kola herb extract and aloe vera herb extract can have beneficial properties in antiaging skin care. The combination of these two herbs can help increase the production of collagen and elastin in the skin, which can help reduce signs of aging such as wrinkles and fine lines. Apart from that, both are also known for their properties which can help protect the skin from sun damage and other environmental factors. ABSTRAKHerbal tradisional telah digunakan sejak ribuan tahun yang lalu untuk tujuan pengobatan dan perawatan kulit. Beberapa jenis bahan lama terkenal dengan khasiat antiagingnya, seperti ekstrak herba pegagan (Centella asiatica L) dan ekstrak daun lidah buaya (Aloe vera L). Keduanya dikenal karena sifat-sifatnya yang bermanfaat dalam menjaga kesehatan dan kecantikan kulit, termasuk efek antioksidan, antiinflamasi, dan regeneratif. Penelitian ini bertujuan untuk mengevaluasi khasiat kombinasi ekstrak herba pegagan dan ekstrak herba lidah buaya sebagai antiaging . Oleh karena itu, kedua ekstrak tersebut perlu dicari referensi terkait. Metode penelitian ini melibatkan studi literatur dari artikel-artikel dan jurnal ilmiah terkait dengan khasiat ekstrak herba pegagan dan ekstrak daun lidah buaya sebagaiantiaging. Data dianalisis dan disusun dalam bentuk sintesis literatur. Hasil dari penelitian ini menunjukkan bahwa kombinasi ekstrak herba pegagan dan ekstrak daun lidah buaya dapat memiliki khasiat yang bermanfaat dalam perawatan kulit antiaging. Kombinasi kedua ekstrak ini dapat membantu meningkatkan produksi kolagen dan elastin dalam kulit, yang dapat membantu mengurangi tanda-tanda penuaan seperti keriput dan garis halus. Selain itu, keduanya juga dikenal karena sifat-sifatnya yang dapat membantu melindungi kulit dari kerusakan akibat sinar matahari dan faktor lingkungan lainnya.
Analisis Tingkat Pengetahuan Masyarakat Tentang Penggunaan Obat Analgetik NSAIDs di Desa Rawakalong Sayyidah, Sayyidah; Aulia, Gina; Fahriati, Andriyani Rahmah; Werawati, Ayu; Saputri, Laras Tri; Herdaningsih, Sulatri; Kristiyowati, Anis Dwi; Alexandre, Nahla Dany; Fitriani, Reka
Edu Masda Journal Vol 7, No 2 (2023): Edu Masda Journal Volume 7 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v7i2.192

Abstract

Pain is the main cause of patients coming to consult a doctor because the number of diseases related to pain reaches 80%. Pain is the main symptom of most medical conditions. Anesthetic drugs serve to reduce pain, mainly through their action on the central nervous system and change a person's response to pain. One of the drugs that are often used to treat inflammation are NSAIDs. The purpose of this study was to determine the level of public knowledge about the use of NSAID analgesic drugs in RT 003 and 004 in Rawakalong Village. The research was conducted using a descriptive research design, with a quantitative approach. Sampling used purposive sampling and the measuring instrument used was a questionnaire distributed to the community of RT 003 and 004 in Rawakalong Village. This study involved 111 respondents who had met the inclusion criteria. Based on the results of the study, it was found that the most age was 17-30 years as many as 51 respondents (46%), the most gender was male as many as 59 respondents (53%), the most education was high school as many as 80 respondents (72%), most occupations were employees as many as 34 respondents (31%), good level of knowledge of respondents as many as 64 respondents (58%), enough as many as 34 respondents (31%), less than 13 respondents (12%). The conclusion is that the level of public knowledge about the use of NSAID analgesic drugs in RT 003 and 004 in Rawakalong Village is 64 people (58%). AbstrakNyeri merupakan penyebab utama pasien datang berkonsultasi dengan dokter karena penyakit yang berhubungan dengan nyeri jumlahnya mencapai 80%. Obat anagetik berfungsi untuk mengurangi rasa nyeri, terutama lewat daya kerjanya atas sistem saraf sentral dan mengubah respons seseorang terhadap rasa sakit. Salah satu obat yang sering digunakan dalam mengatasi inflamasi adalah NSAIDs. Tujuan penelitian ini adalah untuk mengetahui tingkat pengetahuan masyarakat tentang penggunaan obat analgetik NSAID di RT 003 dan 004 Desa Rawakalong. Penelitian dilakukan dengan menggunakan rancangan penelitian deskriptif, dengan pendekatan kuantitatif. Pengambilan sampel menggunakan purposive sampling. Penelitian ini melibatkan 111 responden yang telah memenuhi kriteria inklusi. Berdasarkan hasil penelitian didapatkan bahwa umur terbanyak 17-30 tahun sebanyak 51 responden (46%), jenis kelamin terbanyak adalah laki-laki sebanyak 59 responden (53%), pendidikan terbanyak adalah SMA sebanyak 80 responden (72%), pekerjaan terbanyak adalah karyawan sebanyak 34 responden (31%), tingkat pengetahuan responden yang baik sebanyak 64 responden (58%), cukup sebanyak 34 responden (31%), kurang sebanyak 13 responden (12%). Kesimpulan tingkat pengetahuan masyarakat tentang penggunaan obat analgetik NSAID di RT 003 dan 004 Desa Rawakalong adalah berpengetahuan baik sebanyak 64 orang (58%).
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN HIDROGEL EKSTRAK ETANOL DAUN KELOR Werawati, Ayu; Dewi, Bheta Sari; Hasanah, Uswatun; Aulia, Gina; Zahra, Annisa Fairuz
Edu Masda Journal Vol 8, No 2 (2024): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v8i2.231

Abstract

Acne vulgaris is an inflammatory skin disease that is widespread in 85% of the human population. This disease occurs when hair follicles are blocked by dead skin cells. In some cases, bacteria such as Staphylococcus sp. triggers the inflammation in acne Moringa leaves are known to have potential antibacterial activity against acne-causing bacteria, such as Staphylococcus aureus. The aim of this research is to develop and evaluate a hydrogel preparation containing ethanol extract of Moringa oleifera L. leaves as an alternative treatment for acne. This research was carried out using an experimental method involving hydrogel formulation with varying concentrations of Moringa leaf extract of 4%, 7% and 10%. The evaluation carried out included organoleptic tests, homogeneity, pH, spreadability, adhesive power, physical stability, and antibacterial activity against Staphylococcus aureus. The research results showed that all hydrogel formulations met the specified quality standards, with appropriate pH, good spreadability and adhesion, and adequate physical stability. The antibacterial activity of the hydrogel also showed relatively strong effectiveness at extract concentrations of 4%, 7% and 10%. This research indicates that Moringa leaf extract hydrogel has the potential to be an effective topical preparation for the treatment of acne. Further research can be carried out by exploring the potential anti-inflammatory activity of the ethanol extract of Moringa oleifera leaves
UJI EFEKTIVITAS SERUM EKSTRAK DAUN KELOR (Moringa oleifera L.) SEBAGAI ANTIJERAWAT Staphylococcus aureus Dewi, Bheta Sari; Werawati, Ayu; Hasanah, Uswatun; Sayyidah, Sayyidah; Dewantoro, Agung; Saputra, Aldi
Edu Masda Journal Vol 9, No 1 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i1.281

Abstract

                                                       ABSTRACTAcne is among the most prevalent dermatological issues caused by the bacterium Staphylococcus aureus. Moringa leaf extract (Moringa oleifera L.) is known to contain bioactive compounds such as flavonoids, tannins, and alkaloids, which serve as anti-acne agents. This research seeks to assess the efficacy of a serum formulated with moringa leaf extract in inhibiting the growth of acne-causing Staphylococcus aureus. The extraction of moringa leaves was carried out using the maceration technique with 96% ethanol serving as the solvent. The extract was then formulated into a serum preparation with concentrations of 4%, 7%, and 10%, using Clindamycin as the positive control and the serum base as the negative control. The antibacterial efficacy was evaluated through the agar well diffusion technique to determine the inhibition zone against Staphylococcus aureus. Each treatment was conducted in triplicate. Additionally, the physical stability of the serum was assessed, covering organoleptic characteristics, homogeneity, pH, spreadability, and adhesion. The findings revealed that moringa leaf extract exhibited inhibitory effects on the growth of Staphylococcus aureus, as evidenced by the presence of inhibition zones. The inhibition zone diameters were 14.21 mm at 4% concentration, 17.30 mm at 7%, and 19.20 mm at 10%. In comparison, the positive control showed a diameter of 30.78 mm, while the negative control showed no inhibition (0 mm). This research suggests that serum formulated with moringa leaf extract holds promise as an effective topical solution for treating acne.                                                  ABSTRAKJerawat ialah satu diantara masalah kulit yang umum disebabkan oleh bakteri Staphylococcus aureus. Ekstrak daun kelor (Moringa oleifera L.) dikenal punya senyawa bioaktif seperti flavonoid, tanin, dan alkaloid sebagai agen antijerawat. Kajian ini memiliki tujuan guna melakukan uji efektivitas serum berbahan dasar ekstrak daun kelor dalam menghambat pertumbuhan bakteri jerawat Staphylococcus aureus. Ekstrak daun kelor diperoleh lewat metode maserasi dengan pelarut etanol 96%. Ekstrak ini kemudian diformulasi ke sediaan serum dengan konsentrasi 4%, 7%, dan 10% serta digunakan Clindamycin sebagai kontrol positif dan basis serum menjadi kontrol negatif. Uji aktivitas antibakteri memakai metode difusi sumuran agar, guna mengukur zona hambat pada Staphylococcus aureus. Perlakuan diulang sebanyak 3 kali. Stabilitas fisik serum juga diuji meliputi organoleptis, homogenitas, pH, daya sebar dan daya lekat. Hasilnya diperoleh bahwa ekstrak daun kelor mempunyai kemampuan menghambat pertumbuhan Staphylococcus aureus bisa diamati dengan adanya zona hambat yang dibentuk. Diameter zona hambat di konsentrasi 4% senilai 14,21 mm, konsentrasi 7% sebesar 17,30 mm, konsentrasi 10% senilai 19,20 mm, kontrol positif senilai 30,78 mm, dan kontrol negatif sebesar 0 mm. Kajian ini memberi indikasi jika serum ekstrak daun kelor punya potensi jadi sediaan topikal yang efektif bagi pengobatan jerawat.
INOVASI SPRAY GEL KOMBINASI SAMBILOTO, BROTOWALI, KUNYIT, DAN LADA HITAM SEBAGAI ALTERNATIF NON-STEROID UNTUK PEMULIHAN EKSIM TOPICAL STEROID WITHDRAWAL Bachtiar, Wahyu; Dewi, Bheta Sari; Werawati, Ayu
Edu Masda Journal Vol 9, No 2 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i2.277

Abstract

                                                        ABSTRACTsynergistically for the treatment of Topical Steroid Withdrawal by inhibiting the main inflammatory pathways (TNF-α and IL-6, IL-17, NF-κB, and MAPK pathways). The objective of this study was to determine the optimal formulation of a spray gel containing extracts of sambiloto, brotowali, turmeric, and black pepper based on physical characteristics (organoleptic properties, pH, and viscosity). The optimal formulation was analysed using Design Expert software version 13 and the Mixture D-Optimal method. The independent variables in this study were brotowali extract, sambiloto extract, and turmeric extract. The dependent variables were black pepper extract 1%, carbopol 0.5%, TEA 1%, citric acid 1%, ethanol 15%, phenoxyethanol 0.5%, and propylene glycol 5%. The results obtained indicate that the optimal formulation is based on the highest desirability value from the analysis using the Design Expert program, which is 0.867. The optimal formulation for the spray gel formulation is 3% brotowali extract, 4% sambiloto extract, and 3% turmeric extract.                                                ABSTRAKSambiloto, Brotowali, Kunyit, Dan Lada Hitam merupakan tanaman yang bekerja sinergis untuk pengobatan Topical Steroid Withdrawal dengan aktivitas menekan jalur-jalur inflamasi utama ( jalur TNF-α dan IL-6, IL-17, NF-κB, dan MAPK). Tujuan penelitian ini adalah untuk menentukan formula optimal sediaan spray gel yang mengandung ekstrak sambiloto, brotowali, kunyit, dan lada Hitam berdasarkan karakteristik fisik (organoleptis, pH dan viskositas). Formula optimal dianalisis menggunakan perangkat lunak Design Expert versi 13 dan melalui metode Mixture D-Optimal. Variabel independen dalam penelitian ini adalah ekstrak brotowali, ekstrak sambiloto dan ekstrak kunyit. Variabel dependen adalah ekstrak lada hitam 1%, carbopol 0,5%, TEA 1%, Asam sitrat 1%, Etanol 15%, Fenoksietanol 0,5% dan Propilenglikol 5%. Hasil yang diperoleh menunjukkan bahwa formulasi optimal didasarkan pada nilai keinginan tertinggi dari hasil analisis menggunakan program Design Expert sebesar 0,867. Formulasi optimal untuk sediaan spray gel adalah ekstrak brotowali 3%, ekstrak sambiloto 4% dan ekstrak kunyit 3%.  
Co-Authors Agung Dewantoro Ahmad Sopian, Ahmad Alexandre, Nahla Dany Andriyani Rahmah Fahriati Anis Dwi Kristiyowati Aryanti, Fitriya Yuni Aulia, Gina Azzahra, Aristi Bachtiar, Wahyu Beny Maulana Satria Bheta Sari Dewi Diah Permata Sari Dian Ratih Laksmitawati Esti Mumpuni Fatwa Hikmatul Kurnia Firdha Senja Maelaningsih Fitriani, Reka Gina Aulia Herdaningsih, Sulatri Kristiyowati, Anis Dwi Kurniawati, Dewi Indah Kusmardi Kusmardi Manuruyah, Phuja Arinda Mochammad Hasan, Mochammad Neneng Sri Purwaningsih Nur Hasanah Nurwulan Adi Ismaya Putri, Annisa Septyana Saputra, Aldi Saputri, Laras Tri Sayyidah Sayyidah Sayyidah Sayyidah Sayyidah Sayyidah, Sayyidah Sheila Meitania Utami Siti Novy Romlah Syamsudin Abdillah Uswatun Hasanah Zahra, Annisa Fairuz