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Journal : Strada Jurnal Ilmiah Kesehatan (SJIK)

Secretion Of PGC-1α By Modulating Physical Exercise To Protect Improving Obesity Prevalence Moch Nasmay Lupita; Desiana Merawati; Sugiharto Sugiharto
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.299

Abstract

This study aims to analyze the response of physical exercise as a modulation of PGC-1α to protect against the increasing prevalence of obesity. This research is a true experimental design with the randomized pretest-posttest control group design using 15 obese women aged 18-22 years, Body Mass Index (BMI) 25-35 kg/m2, normal blood pressure, Resting Heart Rate (RHR) normal, VO2max 25-35 ml/kg/min and randomly divided into three groups, namely CONT (n=5, Control Without Intervention), MIIE (n=5, Moderate Intensity Interval Exercise) and MICE (n=5, Moderate Intensity Continuous Exercise). The intervention was carried out at 07.00-09.00 a.m. MIIE and MICE interventions carried out for 40-45 minutes using a treadmill. Pre-exercise blood sampling and 10 minutes post-exercise. Measurement of PGC-1α levels used the Enzyme-Linked Immunosorbent Assay (ELISA) method. Data analysis techniques used ANOVA test and LSD post hoc test with the Statistical Package for Social Science (SPSS)
Interval Exercise Decreases Inflammatory Markers In Obese Female Muhammad Aufar Adfani Irawan; Desiana Aufar Adfani Merawati; Sugiharto Sugiharto
STRADA : Jurnal Ilmiah Kesehatan Vol. 10 No. 1 (2021): May
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v10i1.705

Abstract

This study was experimental research with a pretest-posttest control group design. The interval exercise was performed for 45 minutes on a treadmill. Blood samples were taken 30 minutes before exercise and 10 minutes after exercise. The ELISA method was used to measure the TNF-α level. Statistical analysis used the Independent Samples T-Test and Paired Sample T-Test with a significance level (p<0.05). The results of the Paired Sample T-Test on CO and IE showed that there were no significant difference in the mean of TNF-α levels between pre-exercise and 10 minutes post-exercise (p>0.05). The results of the Independent Samples T-Test showed that there were no significant difference in the mean of TNF-α levels on CO and IE in pre-exercise (p>0.05), while the mean of TNF-α levels in 10 minutes post-exercise between CO vs IE showed a significant difference (p<0.05)