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Hubungan Antara Lama Sakit dengan Kualitas Hidup Anak Penderita DMT1 Saat Pandemi Covid-19 di RSUD Soetomo Surabaya Kevin Almas Maromi; Nur Rochmah; Bambang Hermanto
Jurnal Ilmiah Universitas Batanghari Jambi Vol 21, No 3 (2021): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v21i3.1694

This study aims to determine the relationship between length of illness and quality of life of people with Type 1 Diabetes Mellitus during the COVID-19 pandemic. This research is an analytical description study with a cross-sectional research approach using a questionnaire with telephone interview techniques. The questionnaire in this study was based on several guidelines and previous research. Measurements using PedsQl 3.2 Diabetes Module. Data were collected using a validated questionnaire consisting of 33 question items. The data was collected during October 2020. A total of 33 questionnaires were successfully distributed to patients at the Children's Clinic of Dr. RSUD Dr. Soetomo Surabaya who participated in this research. The data were then analyzed by non-parametric test using the Spearman correlation test method using IBM SPSS Statistics 25. Based on the quality of life assessment using the PedsQL questionnaire, 17 respondents (51.6%) had a near-poor quality of life, and 16 respondents had a near-good quality of life. The most disturbed domain is related to worry, which is as many as 20 respondents (60.7%). Meanwhile, the proportion of respondents with the highest quality approaching good was found in treatment I as many as 19 respondents (57.6%). There was also a positive and significant correlation between related to the disease, P Value 0.007 < 0.05, related to treatment I, P Value 0.011 <0.05, related to anxiety, P value 0.009 < 0.05, and related to communication, P Value of 0.016 < 0.05. In addition, there was also a significant negative relationship with regard to treatment II, P Value 0.000 < 0.05.

Metode Pemeriksaan Kualitas General moveÂ ments Meningkatkan Nilai Prediksi UltrasonoÂ grafi Kepala untuk Memprediksi Perkembangan Bayi Kurang Bulan dari Ibu Preeklamsia Berat Nur Rochmah; Ahmad Suryawan; Moersintowarti BN; Darto Saharso; Fatimah Indarso
Sari Pediatri Vol 14, No 1 (2012)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Latar belakang. Kelahiran kurang bulan dan preeklamsia berat merupakan faktor risiko penyimpangan perkembangan. Deteksi dini perkembangan sangat penting. Hal tersebut memberi peluang intervensi awal dengan hasil optimal. Pemeriksaan ultrasonografi kepala mempunyai keterbatasan dalam memprediksi outcome perkembangan bayi kurang bulan. Pemeriksaan general movementslebih murah dan dapat digunakan di negara berkembang dengan sarana diagnostik yang terbatas. Penambahan pemeriksaan kualitas general movementsdapat meningkatkan nilai prediksi dibandingkan dengan pemeriksaan ultrasonografi kepala saja. Tujuan. Melakukan analisis nilai prediksi ultrasonografi kepala, pemeriksaan general movements,dan kombinasi keduanya untuk memprediksi status perkembangan bayi kurang bulan.Metode. Studi longitudinal diagnostik, dilakukan di RS Dr Soetomo Surabaya pada bulan Desember 2009 sampai Juni 2010. Pemeriksaan ultrasonografi kepala dilakukan pada usia 2 minggu pertama, general movementspada usia 52 minggu gestasi, dan status perkembangan dievaluasi dengan Denver II pada usia 4 bulan usia koreksi. Data dianalisis menggunakan SPSS 12.0. Persetujuan kelaikan etik dikeluarkan oleh RS Dr Soetomo, Surabaya. Hasil.Delapan belas bayi kurang bulan (<37 minggu gestasi) mengikuti penelitian.mempunyai nilai sensitivitas (SN), spesivisitas (SP), nilai prediksi positif (NPP), nilai prediksi negatif (NPN), dan likelyhood ratio(LR) ultrasonografi kepala (0,2;1,0;1,0;1;0,50;5,0), sedangkan general movements (0,90;0,75;0,82;0,86;3,60). Kombinasi kedua pemeriksaan tersebut mempunyai nilai prediksi (0,80;0,50;0,67;0,67;1,60). Kesimpulan.Penambahan pemeriksaan kualitas general movementsdapat meningkatkan sensitivitas outcomeperkembangan bayi kurang bulan dibandingkan hanya pemeriksaan ultrasonografi kepala saja.

Diabetic ketoacidosis in children: an 11-year retrospective in Surabaya, Indonesia Nur Rochmah; Muhammad Faizi; Netty Harjantien
Paediatrica Indonesiana Vol 55 No 1 (2015): January 2015
Publisher : Indonesian Pediatric Society

Background Diabetic ketoacidosis (DKA) is a complication of type I diabetic mellitus (TIDM). Early recognition and prompt treatment can reduce mortality. Objective To evaluate the profiles of patients with diabetic ketoasidosis in Dr. Soetomo Hospital, Surabaya, Indonesia. Methods Retrospective medical records of patients admitted to the pediatric intensive care unit with DKA in Dr. Soetomo Hospital, Surabaya, Indonesia from January 2002 to June 2013 were reviewed. The data collected included clinical parameters, laboratory and imaging results, predisposing factors, complications and outcomes. Results During an 11 years period, there were 58 cases of DKA in children with T1DM. Eighteen subjects (31%) were boys. The severity of DKA was classified as follows: mild 13 (22.4%), moderate 23 (39.7%), and severe DKA 22 (37.9%). Recurrent DKA was diagnosed in 24 (41.4%) patients. Common clinical profiles recorded were dehydration 46 (79.3%), malaise 37 (63.8%), decreased consciousness 35 (60.3%), dyspnea 27 (46.6%), vomiting 26 (44.8%), fever 25 (43.1%), seizure 13 (22.4%), and decreased body weight 9 (15.5%). Laboratory results observed were as folllows: hyponatremia 19 (32.8%), hyperkalemia 12 (20.7%) and acute renal failure 3 (5.2%). Head CT scans showed that 2 (3.4%) patients suffered from cerebral edema. Infections, as triggers of DKA, were found in 12 (20.6%) patients: 4 caries and periodontitis, 3 urinary tract infections, 2 acute diarrhea, 2 acute pharyngitis, and 1 otitis externa. Four out of 24 patients with recurrent DKA failed to take their insulin dose prior to DKA. The average of length of patient stay in the PICU was 3.26 (SD 3.50) days. No patients died during the study. Conclusion Dehydration is the most common clinical profile of DKA in our study. More than half of the patients suffer from moderate to severe DKA.

Impact of growth hormone treatment on childrenâ€™s height Nur Rochmah; Muhammad Faizi
Paediatrica Indonesiana Vol 54 No 6 (2014): November 2014
Publisher : Indonesian Pediatric Society

Background The use of growth hormone (GH) is a routine treatment for growth hormone deficiency (GHD), small for gestational age (SGA), and Turner syndrome (TS). During the treatment, height measurement at regular intervals is a vital step to assess success. To date, there have been no previous studies on GH treatment in Dr. Soetomo Hospital, Surabaya, the referral hospital in East Indonesia. Objective To compare body height between pre- and post-growth hormone treatment in pediatric patients. Method This study was a non-randomized, pre-post clinical trial performed at Dr. Soetomo Hospital, Surabaya. The prospective cohort was accessed during January 2008-June 2013. The inclusion criteria was GH treatment for more than 3 months.Clinical data on GH treatment, including diagnosis, age, height pre-and post-treatment, height gain, duration of treatment, and parental satisfaction were collected. Two-tailed, paired T-test and Pearsonâ€™s test were used for statistical analyses. Result Nineteen patients underwent GH treatment during the study period, but only twelve patients had complete data and were included in the study. Eight subjects were female. Subjectsâ€™ meanage was 11 (range 8-15) years. Nine patients had GHD, 2 had TS, and 1 had SGA. Mean pre-treatment height was 121.05 cm, while mean post-treatment height was 130.5 cm. Mean duration of treatment was 10.5 (range 3-30) months. Mean height gain was 0.8 cm/month in GHD and SGA cases, and 0.78 cm/month for the TS cases. Eleven parents reported satisfaction with the results of GH treatment in their children. There is significant diffrent between pre- and post-treatment (P=0.001). Pearsonâ€™s correlation test (r=0.90) revealed a strong correlation between growth hormone treatment and height gain. Conclusion Growth hormone treatment has impact on heights in GH defficiency, Turner syndrome, and small for gestational age.

Diabetes duration and thyroid stimulating hormone levels in children with type 1 diabetes mellitus Nur Rochmah; Muhammad Faizi
Paediatrica Indonesiana Vol 58 No 2 (2018): March 2018
Publisher : Indonesian Pediatric Society

Background Children with type 1 diabetes mellitus (T1DM) are at risk of thyroid dysfunction. An association between diabetes duration and thyroid stimulating hormone level remains inconclusive. Objective To assess for a possible association between diabetes duration and thyroid stimulating hormone levels in children with T1DM. Methods We conducted a cross-sectional study from January to June 2017 in the Pediatric Endocrine Outpatient Clinic at Dr. Soetomo Hospital. Subjects were children with T1DM aged 7 to <18 years. Exclusion criteria were children with diabetic ketoacidosis, previously diagnosed thyroid problems, and hospitalization in the pediatric intensive care unit (PICU).Â Results From the 55 regular patients in our outpatient clinic, 34 patients were included in the study. Nineteen (54.3%) subjects were male, and the overall mean age was 11.3 years. Subjects' mean duration of diabetes was 3 years and their mean thyroid stimulating hormone concentration was 3.76mIU/L. Pearson's correlation test revealed no significant association between duration of diabetes and thyroid stimulating hormone level (rs=-0.068; P=0.703). Conclusion There is no significant association between duration of diabetes and thyroid stimulating hormone levels in children with T1DM.

Psychological aspects of precocious puberty child during the COVID-19 pandemic Nurul Ima Suciwiyati; Nur Rochmah; Muhammad Faizi; Fadhil Abiyyu Yofi
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.139-145

HIGHLIGHTS 1. Presents a longitudinal case of a child with Organic Central Precocious Puberty (CPP).2. Focused on psychological aspect during the COVID-19 pandemic. ABSTRACT Objective: To present a longitudinal case of a child with organic Central Precocious Puberty (CPP) that focused on medical, growth and development, and parent’s psychological aspect during the COVID-19 pandemic. Case Report: A 14-month old girl attended with major complaints of breasts enlargement and menstruation. The Tanner's stage was at A1M3P1 and the vagina showed reddish-brown spots. The patient’s bone age was advanced (3 years and 6 months). USG examination showed a corpus uterine: cervix ratio of 2:1. GnRH stimulation test showed an elevated of FSH/LH and estradiol. MRI showed an extra-axial dense mass that leads to Hypothalamic Hamartoma (HH). The definitive diagnosis of this patient was organic CPP with HH. The patient was managed with GnRH analog. Precocious puberty (PP) becomes a financial and psychosocial burden for parents. The COVID-19 pandemic adds a double burden for the parents. Conclusion: During the COVID-19 pandemic, parents with PP children had a good psychological aspect if the child was comprehensively handled with adequate motivation and psychoeducation.

EMPOWERMENT OF DIABETES MELLITUS PATIENT DURING COVID-19 PANDEMIC ERA THROUGH ONLINE GATHERING Nur Rochmah; Sukmawati Basuki; Fatimah Arief; Muhammad Faizi; Faisal Faisal; Juniastuti Juniastuti; Herman Kosasih
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 4 No. 2 (2022): OCTOBER 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpmk.v4i2.37884

Introduction: In the COVID-19 pandemic, social restriction and lock-down policies were implemented. It has far-reaching implications in many sectors of life including health, particularly in patients with chronic diseases, one of which is Type-1 Diabetes Mellitus (T1DM). The purpose of this community service in the form of online gathering is to facilitate patients to ask questions and consult with pediatricians, due to the limitations of patients to consult directly due to the pandemic. Methods: Community service is conducted online for T1DM patients or their relatives on Sunday, September 26, 2021, from 12.00 - 13.30 WIB. The Community service was divided into several stages, including before, during, and after the online gathering.Â The T1DM patients or their relatives are participants in this community services. The topic are types of Diabetes Mellitus, clinical presentation, disease progression, the diagnostic process, and its management therapy of type 1 diabetes mellitus. Results: The community service was attended by 54 parents of T1DM patient. The online gathering goes smoothly, without being constrained by something. During the online gathering, subjects actively participate in every session during the online gathering. Several questions were asked by the participants and answered well by the speakers. Conclusion: This community services activities allow participant to be able to ask question about their problem according to diabetes mellitus. Participants can consult online with pediatricians. This online gathering has a limited time, so participants can be divided into several breakout rooms with several accompanying pediatricians, so that the QnA session can be done optimally.

Hubungan Fungsi Tiroid Dengan Pertumbuhan Pada Anak Sindrom Down Di Poli Endokrin Anak Rsud Dr. Soetomo Surabaya Hafidhatul Aisy; Nur Rochmah; Hermawan Susanto; Azwin Mengindra Putera Lubis
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Anak-anak dengan Sindrom Down (SD) memiliki peningkatan risiko mengalami disfungsi tiroid. Hormon tiroid berperan penting dalam proses pertumbuhan sehingga gangguan fungsi tiroid dapat mempengaruhi pertumbuhannya. Penelitian ini bertujuan untuk mengetahui hubungan antara fungsi tiroid dengan pertumbuhan pada anak SD. Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross-sectional menggunakan sumber data rekam medis pasien. Variabel bebas dalam penelitian ini adalah fungsi tiroid dan variabel terikatnya adalah pertumbuhan. Tinggi/ panjang badan merupakan parameter pertumbuhan yang dinilai menggunakan kurva standar untuk anak-anak dengan SD. Hasil dari penelitian ini adalah subjek penelitian terdiri dari 27 pasien SD (17 laki-laki, 20 perempuan) yang berusia 1 sampai 47 bulan dengan rerata usia 10.00Â±10.87 bulan. Distribusi fungsi tiroid terdiri dari 15 hipotiroid sentral (55.6%), 8 hipotiroid subklinis (29.6%), 3 hipotiroid primer (11.1%), dan 1 eutiroid (3.7%). Mayoritas subjek memiliki tinggi badan normal (22/27, rerata z-score -0,03Â±2,37). Nilai signifikansi korelasi antara fungsi tiroid (kadar TSH dan FT4) dan pertumbuhan (perubahan z-score) berturut-turut p=0,287 dan p=0,143 yang berarti p>0,05 sehingga tidak ada korelasi yang signifikan. Sehingga dapaty diterik kesimpulan bahwa tidak terdapat hubungan antara fungsi tiroid dengan pertumbuhan anak dengan SD. Namun disarankan untuk melakukan skrining fungsi tiroid, mendiagnosis, memonitor, dan memberikan terapi dini pada anak SD untuk mencegah perburukan kondisi perkembangan, pertumbuhan, dan metabolisme.

Hubungan Fungsi Tiroid Dengan Pertumbuhan Pada Anak Sindrom Down Di Poli Endokrin Anak Rsud Dr. Soetomo Surabaya Hafidhatul Aisy; Nur Rochmah; Hermawan Susanto; Azwin Mengindra Putera Lubis
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Anak-anak dengan Sindrom Down (SD) memiliki peningkatan risiko mengalami disfungsi tiroid. Hormon tiroid berperan penting dalam proses pertumbuhan sehingga gangguan fungsi tiroid dapat mempengaruhi pertumbuhannya. Penelitian ini bertujuan untuk mengetahui hubungan antara fungsi tiroid dengan pertumbuhan pada anak SD. Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross-sectional menggunakan sumber data rekam medis pasien. Variabel bebas dalam penelitian ini adalah fungsi tiroid dan variabel terikatnya adalah pertumbuhan. Tinggi/ panjang badan merupakan parameter pertumbuhan yang dinilai menggunakan kurva standar untuk anak-anak dengan SD. Hasil dari penelitian ini adalah subjek penelitian terdiri dari 27 pasien SD (17 laki-laki, 20 perempuan) yang berusia 1 sampai 47 bulan dengan rerata usia 10.00Â±10.87 bulan. Distribusi fungsi tiroid terdiri dari 15 hipotiroid sentral (55.6%), 8 hipotiroid subklinis (29.6%), 3 hipotiroid primer (11.1%), dan 1 eutiroid (3.7%). Mayoritas subjek memiliki tinggi badan normal (22/27, rerata z-score -0,03Â±2,37). Nilai signifikansi korelasi antara fungsi tiroid (kadar TSH dan FT4) dan pertumbuhan (perubahan z-score) berturut-turut p=0,287 dan p=0,143 yang berarti p>0,05 sehingga tidak ada korelasi yang signifikan. Sehingga dapaty diterik kesimpulan bahwa tidak terdapat hubungan antara fungsi tiroid dengan pertumbuhan anak dengan SD. Namun disarankan untuk melakukan skrining fungsi tiroid, mendiagnosis, memonitor, dan memberikan terapi dini pada anak SD untuk mencegah perburukan kondisi perkembangan, pertumbuhan, dan metabolisme.

Antibodies to Glutamic Acid Decarboxylase-65 is Associated with Total Daily Dose of Insulin Requirement in Children with Type 1 Diabetes Faisal Faisal; Nur Rochmah; Muhammad Faizi; Novina Novina; Erni Nuraeni
The Indonesian Biomedical Journal Vol 15, No 4 (2023)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v15i4.2377

BACKGROUND: Type 1 diabetes (T1D) mostly occurs due to the destruction of pancreatic beta cells due to autoimmune processes. Diagnosis of T1D can be established by examining the c-peptide levels and the markers of pancreatic autoantibodies, including glutamic acid decarboxylase 65 autoantibodies (GAD-65). However, the association between c-peptide and anti-GAD-65 toward patients’ clinical manifestations needs to be further explored. Hence, the aim of current study was to identify the association of anti-GAD65 with c-peptide and clinical characteristics in children with T1D.METHODS: Case-control study involving 47 T1D children (T1D group) and 41 healthy children (control group) younger than 18 years old was conducted. Secondary data regarding subjects’ demographic characteristics and medical history were collected from subjects, and serum blood was drawn from each subject for the anti-GAD65 and c-peptide measurement. Anti-GAD65 and c-peptide levels were measured using an Enzyme-Linked Immunosorbent Assay (ELISA) methods.RESULTS: Anti-GAD65 antibody was detected in 78.7% T1D group, while only 2.43% were detected in control group subject (p=0.0000). The c-peptide level of T1D group was 0.07±0.19 nmol/L and control group was 1.5±0.77 nmol/L (p=0.0000). The total daily dose of insulin in subjects with positive anti-GAD65 was greater than in the negative anti-GAD65 (p=0.012). The sensitivity and specificity of the anti-GAD65 were 85.4% was 66.7%, respectively.CONCLUSION: The results of this study show that anti-GAD65 was associated with total daily dose of insulin requirement in children with T1D.KEYWORDS: diabetes mellitus, type 1 diabetes, anti-GAD65, c-peptide

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