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All Journal International Journal of Public Health Science (IJPHS) Jurnal Ilmiah Farmasi Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Klinik Indonesia Jurnal Dinamika Pengabdian (JDP) Jurnal Surya Masyarakat PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Surya Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Borneo Journal of Pharmacy
. Lolita
Universitas Ahmad Dahlan
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Other

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Pendampingan Pembuatan Lilin Aromaterapi sebagai Upaya Meningkatkan Kesehatan Mental pada Diaspora Indonesia di Tiongkok Azis Ikhsanudin; Sucipto Sucipto; Wajiran Wajiran; Lolita Lolita; Leoni Nanda Wulandari
Jurnal Surya Masyarakat Vol 8, No 1 (2025): November 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.8.1.2025.20-31

Abstract

Mental health is a crucial determinant of overall well-being. In Indonesia, the prevalence of emotional mental disorders among individuals over 15 years old has reached 9.8% of the population. Indonesian diaspora students in China face unique challenges that may increase the risk of mental health decline. This study aimed to describe the mental health status of Indonesian diaspora students in China and to evaluate aromatherapy candle-making activities as a preventive approach to mental health decline. A descriptive qualitative design was employed using a modified and validated version of the World Health Organization-Five Well-Being Index (WHO-5) questionnaire, validated with 10 respondents. Data were collected from Indonesian students through self-administered questionnaires. Additionally, a workshop on aromatherapy candle-making was conducted to explore its potential benefits for mental health improvement. The findings indicated that students experienced negative emotions with a mean score of 3.41 ± 0.95, self-satisfaction with 3.41 ± 0.73, concentration with 3.45 ± 0.80, and body image perception with 3.68 ± 0.95. Most participants expressed interest in aromatherapy candles, perceiving them as beneficial for mental relaxation and emotional well-being. Indonesian diaspora students in China demonstrated tendencies toward feelings of loneliness, hopelessness, anxiety, and depression. Aromatherapy candle-making activities provided a promising alternative approach to mental relaxation, although further research is needed to determine their effectiveness in improving overall mood and mental health.
Integrative functional annotation of rheumatoid arthritis risk genes using a multi-database bioinformatics approach Muhammad Nuh; Lolita Lolita
International Journal of Public Health Science (IJPHS) Vol 15, No 3: September 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i3.27002

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease involving the interaction of genetic and immunological factors. Genome-wide association studies (GWAS) have identified many RA risk loci, but the biological mechanisms linking genetic variation to disease pathogenesis are not yet fully understood. This study aims to prioritize RA candidate genes through a multi-database bioinformatics approach. SNPs significantly associated with RA were obtained from the GWAS catalog, followed by linkage disequilibrium (LD) screening and functional annotation to identify missense variants. The data were integrated with cis-expression quantitative trait loci (cis-eQTL) information, gene ontology (GO) annotation, and Kyoto Encyclopedia of Genes and Genomes (KEGG) molecular pathway mapping. Genes with a total score ≥2 were classified as RA risk genes. A total of 3.145 RA-significant SNPs were identified, of which 58 were missense variants that could potentially affect protein function. The integration of cis-eQTL and functional annotation resulted in a number of candidate genes with the highest scores (score = 4), where TYK2, IL23R, and IRAK1 were identified as priority RA genes in the main immune pathways, namely JAK-STAT signaling, IL-23/Th17 axis, and Toll-like receptor-NF-κB signaling. These findings demonstrate that this multi-database-based bioinformatics approach successfully identifies RA candidate genes with strong biological relevance.
Co-Authors Adnan, Adnan Andriana Sari Asih Istiani Aulea Rahmawati Aulia Rahmah Azis Ikhsanudin Daniar Dyanas Rais Dewi Kurniati Eka Angriani Hasan Fairuz Yaumil Afra Fauzia Fauzia Heni Lutfiyati Ikrimah Ikrimah Isrovanigoro Isrovanigoro Ivong Rusdiyanti Leoni Nanda Wulandari Mas Ulfah Lestari Meita Putri, Ni Putu Isabela Metalia Puspitasari Muhammad Nuh Ni Putu Isabela Meita Putri Nurjannah Nurjannah Prasojo Pribadi Ratih Oktri Nanda Rayi Citra Ayu Pangestuti Rossie Wiedya Nusantara Silvia Mareti Sucipto, Sucipto Tri M. Andayani Wajiran Wiwik Indayati YVI, Urai Suci Zayyana Septya Ramadani Zijie Wang