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All Journal Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Jurnal Media Gizi Indonesia (MGI) IJNP (Indonesian Journal of Nursing Practices) Jurnal Kesehatan Jurnal Ilmu dan Teknologi Kesehatan Jurnal Keperawatan Terpadu (Integrated Nursing Journal) JURNAL MEDIA KESEHATAN SANITAS: Jurnal Teknologi dan Seni Kesehatan Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Keperawatan Raflesia Indonesian Journal of Global Health research Poltekita: Jurnal Pengabdian Masyarakat Caring : Jurnal Pengabdian Masyarakat Jurnal Vokasi Kesehatan JURNAL PENELITIAN TERAPAN KESEHATAN Journal Of Health & Cardiovascular Nursing Proceeding of Bengkulu International Conference on Health Jurnal Pengabdian Kepada Masyarakat Pusat Unggulan Iptek Penanggulangan Stunting Berbasis Kesehatan Ibu dan Anak Jurnal Vokasi Keperawatan (JVK) Poltekita: Jurnal Ilmu Kesehatan
Dahrizal Dahrizal
Poltekkes Kemenkes Bengkulu
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Clinical Retrospective Cohort Study on the Effectiveness of Chitosan Zinc Oxide Cream for Accelerating Healing in Diabetic Ulcer Patients Dahrizal, Dahrizal; idramsyah, Idramsyah; Septiyanti, Septiyanti
Poltekita: Jurnal Ilmu Kesehatan Vol. 19 No. 1 (2025)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v19i1.3793

Abstract

The evolution of wound dressings has shifted from simply covering wounds to maintaining a moist environment. Chitosan, derived from chitin, and Zinc Oxide (ZnO) are well-known for their roles in wound healing. Chitosan is used due to its natural polymer properties, and ZnO is used to promote cell growth. This study investigates the effectiveness of chitosan zinc oxide cream as a primary dressing to enhance wound healing in diabetic ulcers. This quantitative research method uses a clinical retrospective cohort design. The sample used 235 verified medical records from 2018 to 2023, namely medical records of patients with stage III-IV diabetic wounds who received a primary dressing of chitosan zinc cream every 2-3 days and there was also documentation of the results of the bates-Jensen wound assessment at the first visit and a minimum of four weeks of treatment. The analysis included univariate and bivariate analyses to correlate treatment with healing progress. The results showed significant improvement (p<0.001) in wound condition after treatment with chitosan zinc oxide cream, including a reduction in wound size and depth, faster removal of necrotic tissue, and increased granulation and formation of epithelial tissue. These findings highlight the efficacy of the cream in treating diabetic ulcers, although further research is needed for other types of cancerous wounds, pressure ulcers, and chronic wounds.
Co-Authors Ade Rosita Agustina, Fatma Ahmad Ade Saputra Anang Wahyudi Anita Yulia Asmawati Asmawati Asmawati Asmawati Belinda Zahara Dewi Buston, Erni Demsa Simbolon Derison Marsinova Bakara Elda Damayanti Febriana, Erna Gina Dwi Anggraini Gita Putri Dewi Hartiana, Hartiana Hendri Heryanto Herman Syah Heru Laksono Husni Husni Husni Husni Idramsyah Idramsyah Jon Farizal, Jon Kimas Anggrey Novrica Maksuk Mardiani Mardiani Maya Kumala Sari Mely Gustina Nair, Harikrisna K. R. Nehru Nugroho Nissa, Suviola Khairu Nur Elly Nur Elly Nurdin, Ria Oktasari Pardosi, Sariman Rahma Annisa Revalina Silmy Alvira Revalina, Revalina Ria Sugesti Rialike Burhan Richa Anggraini Ruran, Marina Sahidan Sahidan Sandy Ardiansyah Septiyanti Septiyanti Septiyanti Septiyanti Septiyanti, Septiyanti Sunita Raden Tafrieani, Windy Tahratul Yovalwan Vira Dwi Rizky Wahyudi Rahmadani Wenny Irma Widia Lestari Widia Lestari Wijaya, Andra Wijaya, Andra Saferi Yorita, Epti Yulinda Zamharira Muslim