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Wahyu Setia Budi
Department Of Physics, Faculty Of Science And Mathematics, Diponegoro University
Arts Astronomy Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Other

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Journal : Physics Communication

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Determination of Neutron Flux in Brain Cancer Boron Neutron Capture Therapy Using Monte Carlo Simulation Arianto, Fajar; Handayani, Liska Tri; Budi, Wahyu Setia; Basuki, Prasetyo
Physics Communication Vol 6, No 2 (2022): August 2022
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/physcomm.v6i2.40277

Abstract

Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which is the Glioblastoma multiforme. One of the main components of the BNCT equipment is the collimator which functions as an exit point for epithermal neutron particles that hit cancer cells. In addition to the experimental method, BNCT research can be carried out by modeling, including using the MCNPX software based on the Monte Carlo Method. This research aimed to determine the flux distribution of fast and epithermal neutrons and the dose rate of fast neutrons and gamma that hit the target cancer cells in the phantom head of ORNL MIRD. Modeling using the MCNPX software has three main parts: cell cards, surface cards, and data cards. A tally is used on the data card to calculate the neutron flux. Based on the calculation of the modeling results, the flux of epithermal neutron is 2.87 x 109 n/cm2.s. The dose ratio of the epithermal to the fast neutron flux is 2.29 x 10-14 Gy.cm2/n. Then, the balance of the dose rate of the epithermal to the gamma is 1.64 x 10-14 Gy.cm2/n, and the ratio of epithermal to thermal neutron flux is 0.004. In this study, the epithermal neutron flux hitting the target cancer cells in cell target was moderated at 4 cm so that at a depth of 8 cm, the energy was converted into thermal neutrons. Based on the analysis of the results, it can be concluded that the neutron flux that will interact with cancer tissue is thermal neutrons, not epithermal neutron flux.
Co-Authors Ade Ika Susan Afgani, Jundi Jundullah Agung Dwiyanto Ahmad Mutohar Ainul Ibnu Khotob Alan Tanjung Aji Prastowo Alfian Rizani Ali Khumaeni Anis Nila Kusuma Anugrah Ariyani S. Arif Fahmi Arifah, Dwi Intan Asep Yoyo Wardaya Astrihasna Shafa Bambang Haris Suhartono, Bambang Haris Choirul Anam Choirul Anam AM Diponegoro Chorirul Anam Dewandaru, Ardian Dewantoro, Fajar Dewantoro, Fajar Dhahryan Dhahryan Dini Desita Dwi Siwi Retnoningsih Eddy Prianto Eko Hidayanto Erni Setyowati Fadil Nazir Fajar Arianto Fatkhiyatul Athiqoh G. B. Suparta Gagoek Hardiman Gagoek Hardiman Gani Gunawan Gani Gunawan Handayani, Liska Tri Harianja, Bernard Hendrika Liana Sari Heri Sugito Heri Sutanto I Wayan Ari Makmur Istifadatun Ni’amah Jundi Jundullah Afgani K Sofjan Firdausi K. Sofjan Firdausi Kesawa Sudarsih Ketut Sofjan Firdausi, Ketut Sofjan Kusminarto Kusminarto Kusminarto Kusminarto Kusminarto Kusminarto Kusworo Adi Liska Tri Handayani Maesadji Tjokro Nagoro Maesadji Tjokro Nagoro Maliki Maliki Maria Carizza Pandora Raharjo Masrokan Masrokan Masrokan, Masrokan Michelson Fahrurazi Much Azam Muhamad Adi Muharam Budi Laksono, Muharam Budi Nora Fajria Nur Dwi Prasetyo Pandora Raharjo, Maria Carizza Prasetyo Basuki Priyono, Setyo Purwanto Purwanto Rini Shintawati Rozanah Rozanah Rusmaharani, Diyah Slamet Riyanto Suhardi Suhardi Sunarsih Sunarsih Supriyati Supriyati Suryono Suryono Susila Wardaya, Susila Susilo Susilo Susilo Susilo Susilo Susilo Sutiah Sutiah Sutrati Melissa Malik Taqwim S, M Ainut Titi Purwati Tri Wulan Tjiptono Tri Wulan Tjiptono Very Richardina Weirna Yusanti Wibowo, Danang Rujito Widiastuti, Ratih Wulandhari Wulandhari Zaenal Arifin