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Simplicia and Extracts Standardization from Jualing Leaves (Micromelum minutum Wight & Arn.) from South Kalimantan Sutomo Sutomo; Herwina Dita Lestari; Arnida Arnida; Agung Sriyono
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.898

Abstract

Jualing (Micromelum minutum Wight & Arn.) is a plant from South Kalimantan that has the potential to be developed as natural medicine. This study aims to establish standardization which includes specific and non-specific parameters of M. minutum leaf simplicia and extracts from three growing locations, namely Banua Botanical Garden, Sultan Adam Forest Park, and Forest Areas with Specific Objects of Rantau, South Kalimantan. The method of setting standardization parameters refers to the Indonesian Herbal Pharmacopoeia and General Standard Extracts Parameters. Organoleptic standardization of simplicia is brownish-green, has a distinctive odor, has a bitter and slightly spicy taste. Microscopic observations showed the presence of stomata, cell walls, cytoplasm, calcium oxalate crystals, upper epidermis, palisade tissue, spongy tissue, cortex, xylem, phloem, lower epidermis, and trichomes. Water content test showed the results of 21.9-22.07%; ethanol extract content of 12.87-13.17%; drying losses 4.64-4.84%; total ash content of 6.04-6.14%; acid insoluble ash content 1.13-1.19%; Pb levels of 0.022-0.025 mg/kg; Cd levels of 0.017-0.020 mg/kg; and Hg levels <0.0004 mg/kg. Extract standardization shows thick green-black, thick-smelling extract and bitter taste. Micromelum minutum leaves contain alkaloids, flavonoids, saponins, terpenoids, tannins, anthraquinones, phenols, and glycosides. Thin Layer Chromatography profiles show the similarity of chemical compounds in each growth location. Other parameters are extract yield of 8.08-8.32%; moisture content of 6.07-6.27%; total ash content of 4.22-4.27%; and acid insoluble ash content 1.11-1.12%. All standardization parameters meet the requirements in the Media Materia Indonesia and the Republic of Indonesia Drug and Food Control Center.
Pharmacognostic Study and Antioxidant Activity of Mundar (Garcinia forbesii King.) leaves from Banua Botanical Gardens of South Kalimantan Sutomo Sutomo; Dina Noor Kamali; Arnida Arnida; Normaidah Normaidah; Agung Sriyono
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1541

Abstract

Mundar (Garcinia forbesii King.) is a plant from South Kalimantan. This plant has chemical contents that have potential as medicine. The purpose of this study is to provide a pharmacognostic picture of a specific, nonspecific and determine the antioxidant activity of G. forbesii leaves. Specific parameters include organoleptic, microscopic testing, thin-layer chromatography profiles, and phytochemical screening. Nonspecific parameters include total ash content, acid insoluble ash content, drying loss, water-soluble extract content, and ethanol-soluble extract content. Antioxidant activity was determined by the DPPH method based on IC50 values. Specific parameter test results are green powder, characteristic odor, and sour taste. Microscopic tests showed stomata, upper epidermis, lower epidermis, cell walls, xylem, phloem, palisade tissue, spongy tissue, and cuticles. Garcinia forbesii leaves contain alkaloids, flavonoids, phenols, tannins, and steroids. The TLC profile showed good separation of polar eluents, and yellow spots appeared after spraying DPPH reagents. The non-specific parameter test is the total ash content of 6.52±0.1%; acid insoluble ash content 1.06±0.08%; drying shrinkage 6.43±0.38%; water-soluble extracts 34.3±0.3%; and ethanol-soluble extracts 23.47±0.35%. Ethanol extract of G. forbesii leaves has antioxidant activity with IC50 of 65.7 ppm. Pharmacognostic study fulfills the requirements, and G. forbesii leaves extract has strong antioxidant activity.
Ethnobotanical Study and Phytochemical Screening of Medicinal Plants Used by Local People in Belangian Village, South Kalimantan Sutomo Sutomo; Vita Vitriana Awaliyah; Arnida Arnida
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2717

Abstract

The local people of Belangian Village are people of the Banjar ethnic group who utilize plants in the surrounding environment for medicinal purposes. This study aims to determine the number of plants, parts of plants that can be used, methods of application, methods of preparation, and phytochemical screening of plants with medicinal properties in Belangian Village. This study employed the descriptive-explorative method. The technique used for data collection was an interview with a semi-structured questionnaire. Respondents of this study were “Pananamba” who were selected by using the Purposive sampling technique. Phytochemical screening was carried out on plants with no previously known scientific names and which had never been tested before. The results showed 17 families and 31 species of plants with medicinal properties. Empirically, the plants were used as medicines for cough, bloody urine, diabetes, cancer, sprue, ulcer, hypertension, skin diseases, nausea, diarrhea, coronary heart disease, sinusitis, kidney stones, cleansing kidneys, menstrual pain, itchy eyes, paralysis, bone pain, increasing stamina, antibiotic, reducing body odor, wounds, bleeding, worm diseases, increasing appetite, boosting the immune system, and yellow fever. The most frequently used part of the plants were the leaves (45%), the most widely used method of preparation was boiling (52%), the most commonly used method of application was by drinking (81%). Phytochemical screening was conducted on three plants: Asam daun, Lukun, and Ulur-ulur. The results of phytochemical screening revealed the presence of quinones, saponins, and terpenoids in Asam daun, saponins in Lukun, and terpenoids in Ulur-ulur.
Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome Arnida Arnida; Maulidia Maulidia; Amalia Khairunnisa; Sutomo Sutomo; Faisal Faisal
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2794

Abstract

Purun Danau (Lepironia articulata (Retz.) Domin) has been shown to have antimalarial and antioxidant activity. This study aimed to standardize simplicia and extract of L. articulata by determining the value of its specific and non-specific parameters. A sampling of L. articulata rhizome was carried out in Guntung Manggis, Haur Gading, and Halat. The standardization method used was based on the Indonesian Herbal Pharmacopoeia and the General Standard Parameter of Extract. The organoleptic observations showed that L. articulata simplicia was reddish-brown in color, chelated taste, and had a specific odor. Microscopic observation showed parts of this plant: epidermis, cortex, endodermis, parenchyma, bundle vessels, and scalariform vessels. Ethanol-soluble extract content was 10.00-12.66%, water-soluble extract content 8.03-10.87%, drying shrinkage 7.10-7.33%, total ash content 2.03-2.52%, acid-insoluble ash 0.33-0.42%, Pb content 5.698-9.989 ppm, Cd content 0.300-0.500 ppm, Hg content 0.070-0.090 ppm. Ethanol extract of L. articulata rhizome contained alkaloids, flavonoids, tannins, glycosides, and saponins. The yield obtained was 8.05-11.23%, total ash content was 1.58-1.67%, acid-insoluble ash was 0.23-0.33%, and water content was 7.10-8.50%. Standardization of simplicia and ethanol extract of L. articulata rhizome has met the criteria.
Antioxidant Activity of n-hexane and Etil Acetate Fractions of Bangkal (Nauclea subdita (Korth.) Steud.) Leaves Arnida Arnida; Al Madani; Sutomo Sutomo
Borneo Journal of Pharmacy Vol. 6 No. 2 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i2.4738

Abstract

Bangkal (Nauclea subdita (Korth.) Steud.) is a tropical plant belonging to the Rubiaceae family, commonly found in South Kalimantan. This plant is one of the plants that has efficacy as a medicinal plant. This study aimed to quantitatively identify secondary metabolites and antioxidant activity in the n-hexane and ethyl acetate fractions of N. subdita leaves. The method of identification of secondary metabolites using the test tube. Antioxidant activity using the DPPH method based on IC50 value. The results of identifying secondary metabolites in the n-hexane fraction of N. subdita leaves contain alkaloids, flavonoids, steroids, and phenolic compounds, while the ethyl acetate fraction of N. subdita leaves contain alkaloids, flavonoids, steroids, tannins, saponins, and phenolics. The results of the antioxidant activity test of the n-hexane fraction and the ethyl acetate fraction of the leaves of N. subdita showed IC50 values ​​of 229.61178±3.65919 and 54.54296±0.02236 ppm, respectively. Based on the IC50 value, the n-hexane fraction of N. subdita leaves had weak antioxidant activity, and the ethyl acetate fraction of N. subdita leaves had strong antioxidant activity.
Pelatihan Penggunaan Tabung Oksigen Sebagai Pertolongan Pertama Pada Sesak Nafas Akibat Kabut Asap Untuk Kesiapsiagaan Bencana Di Desa Benua Raya: Indonesia Hafiz Ramadhan; Dyera Forestryana; Liana Fitriani Hasymi; Sutomo Sutomo; Amalia Khairunnisa; Wiwin Tyas Istikowati
Prosiding Seminar Nasional Pengabdian Masyarakat Vol. 2 (2024): Prosiding Seminar Nasional Pengabdian Masyarakat
Publisher : CV. Dharma Samakta Edukhatulistiwa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61142/psnpm.v2.185

Abstract

Kasus kebakaran hutan dan lahan dapat menyebabkan dampak negatif emisi kabut asap sehingga mengakibatkan masalah kesehatan yang serius seperti sesak nafas. Puskesmas dapat menjadi pelayanan darurat pasca bencana, akan tetapi dengan jumlahnya yang terbatas, peran kader Posyandu sangat diperlukan dalam membantu mengatasi masalah kesehatan akibat bencana. Tujuan pengabdian kepada masyarakat ini untuk menginisiasi kesiapsiagaan kader posyandu dalam menghadapi bencana kebakaran hutan dan lahan untuk mencegah terjadinya gangguan kesehatan melalui edukasi dan pelatihan penggunaan tabung oksigen sebagai pertolongan pertama pada sesak nafas akibat kabut asap di Desa Benua Raya, Kecamatan Bati-Bati, Kabupaten Tanah Laut. Kegiatan dilakukan melalui penyuluhan dan pelatihan penggunaan seperangkat tabung oksigen kepada Ibu-ibu kader Posyandu dengan total 14 orang pada tanggal 18 November 2024. Hasil kegiatan menunjukkan bahwa peserta mengetahui dan memahami dampak terhadap kesehatan serta tindakan yang harus dilakukan dalam membantu permasalahan kesehatan akibat kabut asap. Persentase pengetahuan sebelum kegiatan yaitu 21,43%-57,14% mengalami peningkatan setelah kegiatan menjadi 100%. Tingkat pengetahuan dan keterampilan peserta dalam penggunaan seperangkat tabung oksigen juga meningkat dari 12,29% menjadi 100%. Kesimpulannya yaitu kegiatan ini dapat menginisiasi Posyandu berbasis kebencanaan untuk meminimalisir tingkat keparahan masalah kesehatan yang diakibatkan oleh kabut asap melalui kompetensi dan keterampilan pertolongan pertama pada sesak nafas menggunakan tabung oksigen.
Pemanfaatan Tumbuhan Berkhasiat Obat Oleh Masyarakat Desa Ujung Kabupaten Kotabaru Kalimantan Selatan Melalui Studi Etnobotani NUR AINA FADHILAH; Sutomo Sutomo; Arnida Arnida
Journal of Pharmascience Vol. 11 No. 2 (2024): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.20852

Abstract

Kalimantan Selatan memiliki keanekaragaman hayati yang dapat dimanfaatkan oleh masyarakat untuk berbagai keperluan. Kajian etnobotani meliputi pengetahuan masyarakat setempat dengan pemanfaatan sumber daya alam berupa tumbuhan di lingkungan sekitarnya, salah satunya sebagai bahan obat. Tujuan penelitian untuk mengetahui secara kuantitatif tumbuhan obat yang dimanfaatkan oleh masyarakat, bagian tumbuhan yang dimanfaatkan, serta mengetahui cara pengolahan dan cara pemanfaatannya. Penelitian ini merupakan penelitian deskriptif eksploratif dengan pendekatan fenomenologi. Metode penelitian yang digunakan adalah wawancara terbuka terencana dengan pengumpulan data menggunakan kuesioner. Metode penelitian yang digunakan dalam menentukan informan adalah metode Purposive Sampling. Informan dalam penelitian berjumlah 5 orang yang memenuhi kriteria yang ditetapkan oleh peneliti. Hasil penelitian menunjukkan bahwa Masyarakat Desa Ujung Kecamatan Pulau Sebuku Kabupaten Kotabaru Kalimantan Selatan telah memanfaatkan 43 jenis tumbuhan obat. Bagian tumbuhan yang paling banyak dimanfaatkan sebagai obat adalah daun 54,17%; kemudian secara berurutan adalah buah (8,33%), batang (6,25%), getah (6,25%), akar (4,17%), kulit pohon (4,17%), dan umbi(2,08%). Cara pengolahan tanaman obat yang paling banyak adalah dengan merebus sebanyak 42%, kemudian berturut-turut tanpa pengolahan (14%), diremas (10%), ditumbuk dan ditambah bahan lain (10%), dimasak(8%), direbus dan ditambah bahan lain (4%), diseduh dan ditambah bahan lain (4%), ditumbuk (2%), diseduh(2%), direndam (2%). Cara pemanfaatan tanaman obat yang paling banyak adalah dengan meminum sebanyak 55,10%; kemudian berturut-turut ditempel (16,3%), dioles (14,3%), dimakan (12,24%), dan diteteskan (2,04%). Dari 43 jenis tanaman obat, bagian tanaman yang paling banyak dimanfaatkan adalah daunnya, dengan cara pengolahan direbus dan digunakan dengan cara diminum.