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All Journal Majalah Obat Tradisional Pharmascience Jurnal Fitofarmaka Indonesia Jurnal Surya Medika Jurnal Jamu Indonesia Majalah Farmasetika Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Nusantara Berbakti Borneo Journal of Pharmacy
Sutomo Sutomo
Universitas Lambung Mangkurat
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome Arnida Arnida; Maulidia Maulidia; Amalia Khairunnisa; Sutomo Sutomo; Faisal Faisal
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2794

Abstract

Purun Danau (Lepironia articulata (Retz.) Domin) has been shown to have antimalarial and antioxidant activity. This study aimed to standardize simplicia and extract of L. articulata by determining the value of its specific and non-specific parameters. A sampling of L. articulata rhizome was carried out in Guntung Manggis, Haur Gading, and Halat. The standardization method used was based on the Indonesian Herbal Pharmacopoeia and the General Standard Parameter of Extract. The organoleptic observations showed that L. articulata simplicia was reddish-brown in color, chelated taste, and had a specific odor. Microscopic observation showed parts of this plant: epidermis, cortex, endodermis, parenchyma, bundle vessels, and scalariform vessels. Ethanol-soluble extract content was 10.00-12.66%, water-soluble extract content 8.03-10.87%, drying shrinkage 7.10-7.33%, total ash content 2.03-2.52%, acid-insoluble ash 0.33-0.42%, Pb content 5.698-9.989 ppm, Cd content 0.300-0.500 ppm, Hg content 0.070-0.090 ppm. Ethanol extract of L. articulata rhizome contained alkaloids, flavonoids, tannins, glycosides, and saponins. The yield obtained was 8.05-11.23%, total ash content was 1.58-1.67%, acid-insoluble ash was 0.23-0.33%, and water content was 7.10-8.50%. Standardization of simplicia and ethanol extract of L. articulata rhizome has met the criteria.
Antioxidant Activity of n-hexane and Etil Acetate Fractions of Bangkal (Nauclea subdita (Korth.) Steud.) Leaves Arnida Arnida; Al Madani; Sutomo Sutomo
Borneo Journal of Pharmacy Vol. 6 No. 2 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i2.4738

Abstract

Bangkal (Nauclea subdita (Korth.) Steud.) is a tropical plant belonging to the Rubiaceae family, commonly found in South Kalimantan. This plant is one of the plants that has efficacy as a medicinal plant. This study aimed to quantitatively identify secondary metabolites and antioxidant activity in the n-hexane and ethyl acetate fractions of N. subdita leaves. The method of identification of secondary metabolites using the test tube. Antioxidant activity using the DPPH method based on IC50 value. The results of identifying secondary metabolites in the n-hexane fraction of N. subdita leaves contain alkaloids, flavonoids, steroids, and phenolic compounds, while the ethyl acetate fraction of N. subdita leaves contain alkaloids, flavonoids, steroids, tannins, saponins, and phenolics. The results of the antioxidant activity test of the n-hexane fraction and the ethyl acetate fraction of the leaves of N. subdita showed IC50 values ​​of 229.61178±3.65919 and 54.54296±0.02236 ppm, respectively. Based on the IC50 value, the n-hexane fraction of N. subdita leaves had weak antioxidant activity, and the ethyl acetate fraction of N. subdita leaves had strong antioxidant activity.
Edukasi Penerapan Teknologi Fermentasi melalui Pembuatan Kefir dan Yogurt Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Arnida Arnida; Sutomo Sutomo; Fadlilaturrahmah Fadlilaturrahmah
Jurnal Nusantara Berbakti Vol. 2 No. 4 (2024): Oktober : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v2i3.411

Abstract

Fermentation technology can increase added value to agricultural, food and other products. Through fermentation, raw materials can be converted into products with higher selling value, such as cheese, yogurt, tempeh, wine, beer, and so on. Many fermented products are beneficial for health, for example kefir and yogurt which contain good probiotics. for digestion. Kefir is a type of fermented milk whose manufacture uses various microorganisms to produce lactic acid products with by-products such as ethanol, free fatty acids and acetaldehyde. Kefir is made by adding yeast which contains many microorganisms from the lactic acid bacteria and yeast groups, while yogurt is fermented milk with lactic acid bacteria (LAB).  This service activity aims to increase people' knowledge and skills regarding the application of fermentation technology, starting from the meaning of fermentation, fermentation methods to high-value products produced from the fermentation process. In this activity, socialization activities were carried out regarding the development of fermentation technology, especially kefir and cow's milk yogurt, as well as practices on how to make it among the residents of Balitra Jaya Permai Loktabat Utara. The results show an increase in residents' knowledge and skills regarding fermentation through pretest and posttest activities as well as practical activities.
Potensi Ekstrak Metanol, Fraksi N-Heksana dan Etil Asetat Daun Kasturi (Mangifera Casturi Kosterm) Terhadap Aktivitasnya Sebagai Anti Bakteri: Potential of Methanol Extract, N-Hexane Fraction and Ethyl Acetate of Kasturi Leaves (Mangifera Casturi Kosterm) for Their Anti-Bacterial Activity Sutomo Sutomo; Ahmad Fajri; Pratika Viogenta; Arnida Arnida; Nasrul Wathan
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.8484

Abstract

Salah satu tumbuhan obat yang secara empiris memiliki aktivitas antibakteri adalah kasturi (Mangifera casturi). Tumbuhan M. casturi merupakan salah satu tumbuhan khas Kalimantan. Penelitian ini bertujuan menentukan aktivitas antibakteri ekstrak metanol, fraksi n-heksan dan fraksi etil asetat daun M. casturi terhadap bakteri Staphyloccocus aureus, Eschericia coli, dan Salmonella typhi. Metode yang digunakan pada penelitian ini yakni metode Kirby-bauer dan Bioautografi dengan konsentrasi ekstrak metanol, fraksi n-heksan dan fraksi etil asetat  sebesar 5, 10, dan 15% serta kontrol positif siprofloksasin dan kontrol negatif Na-CMC 0,5%. Hasil menunjukkan bahwa diameter zona hambat ekstrak metanol, fraksi n-heksana dan fraksi etil asetat secara berurutan didapat 14,4; 9,21; dan 14,63 mm pada bakteri St. aureus, 14,43; 16,01; dan 17,21 mm pada bakteri E. coli serta 10,23; 8,4; dan 12,21 mm pada bakteri S. typhi. Hasil KLT-Bioautografi dengan eluen n-heksana : etil asetat (5:5)v/v pada fraksi etil asetat dengan Rf 0,45 terdapat zona hambat terhadap S. typhi. Hasil analisis menunjukkan bahwa pemberian perlakuan  ekstrak metanol, fraksi n-heksana dan fraksi etil asetat pada konsentrasi 5, 10, dan 15% berbeda signifikan terhadap kontrol negatif dan positifnya. Fraksi etil asetat daun M. casturi merupakan hasil yang terbaik dalam menghambat bakteri St. aureus, E. coli dan S. typhi. Dengan demikian dapat dikatakan bahwa daun tumbuhan M. casturi berpotensi dalam menghambat pertumbuhan bakteri.
Co-Authors Agung Nugroho Agung Sriyono Ahmad Fajri Al Madani Amalia Khairunnisa Amida Amida Arnida Arnida Arnida Arnida Aulea Rahmawati Buih, Putri Helena Junjung Dina Noor Kamali Eka Rahmawaty Sahi Evi Mintowati Fadilaturrahmah Fadilaturrahmah Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillahturrahmah Fahriah Fahriah Faisal Faisal Hadi Azhari Herwina Dita Lestari Lia Rosyidah Liling Triyasmono Maulidia Maulidia Mia Fitriana Muhammad Ikhwan Rizki Muhammad Rafi Nadya Agustina Najat Su'aida Nanang Fakhrudin, Nanang Nani Kartinah Nasrul Wathan Nhaya Riskita Normaidah, Normaidah Nurlely, Nurlely Nurmalita Sari Peni Susilowati Putri Prima Happy Ratnapuri Rahmat Yunus Salamiah Salamiah Siti Humairah Z.A Subagus Wahyuono Utsna Uhdatul Khoriah Viogenta, Pratika Vita Vitriana Awaliyah