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All Journal Tropical Medicine Journal Jurnal Kesehatan Andalas Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Anakes: Jurnal Ilmiah Analis Kesehatan
I Gusti Ayu Nyoman Danuyanti
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Hubungan Titer Widal Dengan Jumlah dan Indeks Trombosit Penderita Demam Tifoid di Puskesmas Wilayah Lombok Barat Widary, Baiq Larasati; Danuyanti, I Gusti Ayu Nyoman; Zaetun, Siti
Andalas Journal of Health Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1792

Abstract

The diagnosis of typhoid fever can be made by hematological examination and the Widal method. Hematologic change that often occurs in typhoid fever is thrombocytopenia. Platelet function can be observed by examining the platelet index, namely the Mean Platelet Volume (MPV), and Platelet Distribution Width (PDW). The titer on the serological examination of the Widal test is a significant diagnostic for infections caused by the bacterium Salmonella typhi. Objectives: To determine the relationship between the Widal titer and the number and index of platelets in patients with typhoid fever at the West Lombok Health Center. Methods: The research methodology used is an analytic observational method with a cross-sectional approach. This study was conducted from February 2021 to April 2021. The population in this study was all patients who underwent laboratory examinations diagnosed as positive for typhoid fever in the Gunungsari Health Center, West Lombok Regency, with a sample of 24 respondents. Data analysis using Spearman correlation. Results: Statistical test results obtained P≥0.05, namely the titer value against platelets p=0.429, the titer against the MPV platelet index p=1,000, PDW p=0.291. Conclusion: there is no relationship between widal titer to the number of platelets and the platelet index in patients with typhoid fever.Keywords:  typhoid fever, platelets, platelet  index, widal titer
Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue Sholihah, Ayu Safitri; Danuyanti, I Gusti Ayu Nyoman; Zaetun, Siti; Ariami, Pancawati; Resnhaleksmana, Ersandhi
Andalas Journal of Health Vol. 11 No. 2 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v11i2.2032

Abstract

Dengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive  Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever.Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic fever
Korelasi Antara Kadar Asam Urat Dalam Darah dan Kristal Asam Urat Dalam Urine Pada Penderita Tuberkulosis Disertai Hiperurisemia Khairunnisa, Nisrina Yola; Danuyanti, I Gusti Ayu Nyoman; Jiwantoro, Yudha Anggit
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.258

Abstract

Tuberculosis is a contagious infectious disease caused by the bacteria Mycobacterium tuberculosis. In tuberculosis patients increased levels of uric acid in the blood. Hyperuricemia is the levels of uric acid in the blood that exceeds the normal limits. The research objective in this study was to determine the correlation between the levels of uric acid in the blood and uric acid crystals in the urine in patients with tuberculosis accompanied by hyperuricemia. The research method used in this study was survey analytic with a cross sectional approach. The research used in this study population was all patients with tuberculosis who check in Health Centers of Mataram and samples total of 24 people. Data analysis used a statistical test Spearman Rank correlation. The results showed that levels of uric acid in the blood that is 8.2 mg/dl while on uric acid crystals in urine mean 0.6/fild of view uric acid crystals. The results indicated a correlation between the levels of uric acid in the blood and uric acid crystals in the urine in patients with tuberculosis accompanied by hyperuricemia. The results of the statistical test Rank Spearman showed a p value of 0.041 < 0.05 and the results of the coefficient correlation showed a value -0.419, its mean the strength of the correlation is medium. The conclusion of this study is that the patients with tuberculosis accompanied by hyperuricemia there is a correlation between the levels of uric acid in the blood and uric acid crystals in the urine.
Co-Authors Ahmad Hamim Sadewa Erna Kristinawati Ersandhi Resnhaleksmana I Gede Billy Sumantri I Komang Agusjaya Mataram, I Komang Agusjaya Jiwantoro, Yudha Anggit Khairunnisa, Nisrina Yola Maruni Wiwin Diarti Ni Putu Agustini Nursardjan Nursardjan Pancawati Ariami Pauzi, Iswari Rahmayanti, Utari Rizki Resnhaleksmana, Ersandhi Resnhaleksmana, Ersandhi Rohmi, Rohmi Sholihah, Ayu Safitri Siti Zaetun Siti Zaetun, Siti Tasmini - Tsamarah, Yumna Tahani Utari Rizki Rahmayanti Widary, Baiq Larasati Yuli Laraeni, Yuli