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GAMBARAN KADAR HEMOGLOBIN PADA MAHASISWI PROGRAM STUDI D3 ANALIS KESEHATAN UNIVERSITAS ABDURRAB DENGAN SIKLUS MENSTRUASI TIDAK TERATUR Fatma Fatma; Rosa Devitria; Amanda Dwinta Harianti
Ensiklopedia Research and Community Service Review Vol 5, No 3 (2026): Vol. 5 No. 3 Juni 2026
Publisher : Ensiklopedia Research and Community Service Review

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/err.v5i3.3939

Abstract

Abstract: Irregular menstrual cycles may alter the amount of blood loss during menstruation and potentially affect hemoglobin (Hb) levels. Persistent decreases in hemoglobin levels can increase the risk of anemia among adolescent girls and female college students. This study aimed to describe hemoglobin levels among female students of the D3 Health Analyst Study Program at Abdurrab University who experienced irregular menstrual cycles. This research employed a quantitative descriptive design with a cross-sectional approach. A total of 30 respondents were selected using purposive sampling according to the inclusion criteria. Hemoglobin levels were measured using the Cyanmethemoglobin method with a spectrophotometer. The results showed that 19 respondents (63.3%) were classified as anemic with Hb levels 12 g/dL, while 11 respondents (36.7%) had normal Hb levels. Based on menstrual cycle characteristics, 17 respondents (56.7%) had cycles longer than 35 days, and 13 respondents (43.3%) had cycles shorter than 21 days. Among respondents with menstrual cycles shorter than 21 days, 11 were anemic and only 2 had normal Hb levels. It can be concluded that most female students with irregular menstrual cycles experienced anemia, particularly those with menstrual cycles shorter than 21 days.Keywords: Hemoglobin, Namenia, Irregular Menstrual Cycle, Female Students.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL BIJI JAMBU BOL (Syzygium malaccense L) DENGAN METODE DPPH (2,2-Diphenyl-1-picrylhidrazil) Rosa Devitria; Siti Juariah; Larasari Putri
Klinikal Sains : Jurnal Analis Kesehatan Vol. 10 No. 1 (2022): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v10i1.2525

Abstract

Antioxidants are compounds that can overcome the negative effects of oxidants in the body. Antioxidants have an important role for the health of human body because they can slow or prevent oxidation that involves free radicals. Free radicals will cause several degenerative diseases. Based on the source, antioxidants are divided into two groups, they are natural antioxidants and synthetic antioxidants. Seeds guava bol is one of the plants that used in traditional medicine which has the potential as a natural antioxidant. The purpose of this study was to determine the antioxidant activity of the methanol extract of seeds guava bol through the IC50 value. The method used in this study is the 2,2-Diphenyl-1-Picrylhidrazil (DPPH) method, which is a method of measuring antioxidants that is fast, simple, accurate and inexpensive. The results showed that the IC50 value was 1.627 ppm. From the IC50 value obtained, it is known that the methanol extract of guava seeds has strong antioxidant activity to fight free radicals.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI JAMBU BOL (Syzygium malaccense L) TERHADAP BAKTERI Bacillus subtilis : UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI JAMBU BOL (Syzygium malaccense L) TERHADAP BAKTERI Bacillus subtilis Rosa Devitria; Yowantyano Dwiki Riaunanda
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.7399

Abstract

Abstract Infectious diseases are medical disorders caused by pathogenic bacteria that infect and multiply within the body in large numbers, leading to illness. Antibiotics are the choice for combating infections and diseases caused by pathogenic bacteria. Guava seeds can be used as a natural ingredient for medicinal plants because they contain secondary metabolite compounds such as flavonoids, phenols, and terpenoids, which are known to have activities as antioxidants, antibacterial, antifungal, antiviral, and anticancer agents. The purpose of this study is to determine the antibacterial activity of ethanol extract of guava seeds in inhibiting the growth of Bacillus subtilis bacteria. The method used in this study is the Kirby-Bauer method, which is a disk diffusion method. Based on the results of the research conducted with concentrations of 20%, 40%, 60%, and 80%, with varying results of 12.43 mm, 15.37 mm, 15.78 mm, and 16.67 mm. These results can be concluded that the inhibition zone produced by the guava seed extract against Bacillus subtilis bacteria falls into the category of strong inhibitory
ANTIOXIDANT ACTIVITY TEST OF METHANOL EXTRACT ON DRAGON FRUIT SKIN (Hylocereus polyrhizus), BENGKOANG (Pachyrhizus erosus) AND GUAVA SEEDS (Syzygium malaccense L) DPPH METHOD (1,1-Dyphenyl-2-Pycrylhydrazyl) Rosa Devitria; Nadila Pratiwi Utami
Jurnal Ilmu Kesehatan Abdurrab Vol. 3 No. 1 (2025): Volume 3 Nomor 1 Maret 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Free radicals are components that lack one electron, so they are very reactive toward other components to complement their electron deficiency. Free radicals have become a frightening component for many people because of the problems they cause, such as premature aging and various degenerative diseases. However, free radicals and the reactions they form can be inhibited by antioxidant compounds. According to WHO (World Health Organization), in 2011 showed that several degenerative diseases such as atherosclerosis, stroke, diabetes mellitus, and others are included in the top ten causes of human death worldwide. To prevent degenerative diseases, antioxidants are needed, which can neutralize free radicals. The function of antioxidants is to help the defense system in the body when disease-generating elements enter and attack the body. Dragon fruit skin, jicama, and guava seeds contain flavonoids to prevent skin damage due to free radicals, and phenolic substances are effective in inhibiting the process of melanin formation. Aims to determine the antioxidant activity test of methanol extract made from dragon fruit skin, Sengkang and guava seeds using the DPPH method. This research is laboratory experimental research. This research is laboratory experimental research. Dragon fruit skin, Sengkang and guava seeds are dried and mashed and then macerated with a methanol solution. Furthermore, testing of antioxidant activity was carried out using the DPPH method (1,1-Dyphenyl-2-Pycrylhydrazyl) and using a microplate reader at a wavelength of 520 nm. The results of the antioxidant activity test of the methanol extract on the antioxidant test of the dragon fruit peel extract sample obtained an IC50₋ value of 286.816 ppm which was included in the weak group; the antioxidant test of the Sengkang extract sample obtained an IC50- value of 31.218 ppm which was included in the weak group. Very strong, the antioxidant test of the guava seed extract sample obtained an IC50- value of 15.958 ppm which is included in the very strong group.
PEMANFAATAN ANTOSIANIN KULIT UBI JALAR UNGU (Ipomoea batatas L.) SEBAGAI BIOSENSOR KANDUNGAN NATRIUM NITRIT PADA PRODUK DAGING OLAHAN Rosa Devitria; Mega Elfia; Ynisa Yulan Sarwis
Ensiklopedia of Journal Vol 5, No 3 (2023): Vol. 5 No. 3 Edisi 3 April 2023
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v5i3.1896

Abstract

Anthocyanins are one of the natural color pigments in plants that have an important physiological function that can be used as a detector of synthetic substances that exceed the limit, especially the use of sodium nitrite in processed meat. Anthocyanins are found in purple sweet potatoes. Therefore, this study aims to maximize the use of Purple Sweet Potato skin as a biosensor of chemical content in food. This type of research is a descriptive research with quantitative laboratory testing using a UV-Vis spectrophotometer test and a qualitative test using whatmann filter paper No.42 as an indicator. The observed parameter was a discoloration that occurred on whatmann filter paper No.42 before and after dripping the tested sodium nitrite solution. The results showed that the skin of Purple Sweet Potato had anthocyanin levels of 119.56 mg / 100 grams, and from the six samples tested, there was no use of sodium nitrite that exceeded the threshold because after dripping the sample juice occurred a light light purple color on the indicator paper that did not show a discoloration to the positive control dripped sodium nitrite concentration of 5% and 10% which was dark blue. So the results show that purple sweet potato skin anthocyanins have the potential to be developed as natural biosensors for testing the content of chemicals in food, specifically in detecting the use of sodium nitrite that exceeds the threshold in processed meat products.  Keywords:      Anthocyanins, Purple Sweet Potato Skin, Sodium Nitrite, Processed Meats 
Uji Daya Hambat Ekstrak NADES Bunga Telang (Clitoria ternatea) terhadap Bakteri Staphylococcus aureus: Inhibitory Test of NADES Extract of Butterfly Pea Flower (Clitoria ternatea) against Staphylococcus aureus Bacteria Siti Juariah; Fitria Desrita Sari; Rosa Devitria; Eli Yusrita; Susi Endrini
Elektriese: Jurnal Sains dan Teknologi Elektro Vol. 16 No. 01 (2026): Artikel Riset Edisi April 2026
Publisher : Yayasan Cita Cendekiawan Al Khwarizmi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47709/elektriese.v16i01.8396

Abstract

Butterfly pea (Clitoria ternatea), also known as butterfly pea, is a climbing plant from the Fabaceae family that has great potential as a source of natural antibacterials. This plant contains various bioactive compounds, including alkaloids, tannins, saponins, anthocyanins, and phenolics, which contribute to its antibacterial activity. This study aims to evaluate the inhibitory effect of butterfly pea flower extract on Staphylococcus aureus growth and to analyze the relationship between extract concentration and antibacterial activity. The research method used a diffusion test with treatment variations in extract concentration (25%, 50%, and 75%), as well as a positive control (chloramphenicol) and a negative control (Aquadest. The diameter of inhibition (DDH) was measured with a caliper to ensure accuracy. In addition, phytochemical screening was performed to identify the active compounds in the extract. The results showed the presence of flavonoids, tannins, alkaloids, phenols, and saponins, all of which act as antibacterial agents. The antibacterial test results showed that butterfly pea flower extract significantly inhibited the growth of Staphylococcus aureus, with a highly significant difference in inhibitory activity across concentrations. The highest antibacterial activity was observed at 75% concentration, with an average DDH of 26.53 mm, placing it in the very strong inhibitory power category. Increasing the extract concentration is consistent with increased antibacterial effectiveness. Butterfly pea flower extract has the potential to be developed into an effective, safe, natural antibacterial alternative.