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All Journal Jurnal Akademika Kimia Jurnal Penelitian Farmasi Indonesia JURNAL PHOTON Klinikal Sains (Jurnal Analis Kesehatan) Ensiklopedia of Journal Human Care Journal Jurnal Sains dan Teknologi Laboratorium Medik International Journal of Social Science Jurnal Farmanesia Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Jurnal Pengabdian Masyarakat Bidang Sosial dan Humaniora Elektriese: Jurnal Sains dan Teknologi Elektro Ensiklopedia Research and Community Service Review JIKA Jurnal Sains Farmasi dan Kesehatan Jurnal Sains dan Kesehatan
Rosa Devitria
Abdurrab University, Indonesia
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Uji Aktivitas Antioksidan Ekstrak Etanol Biji Jambu Bol (Syzygium Malaccense (L.) Merr. & Perry) Dengan Metode 1,1-Diphenyl-2-Picryhidrazyl (DPPH) Rosa Devitria; Mega Elfia; Manisha Tri Cahyani
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 2 No 1 (2023): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v2i1.694

Abstract

Many plants include antioxidant chemicals in their blooms, leaves, and fruit. Antioxidants are substances that slow, stop, or stop the oxidation process. Various antioxidant chemicals have the capacity to block oxidative processes, allowing body cells to recover from oxidative damage. Malay apple has a lot of antioxidant and anti-inflammatory properties. Malay apple flesh, seeds, and leaves include phenolic chemicals, flavonoids, and carotenoids, all of which have antioxidant properties. The IC50 value will be used to measure the antioxidant activity of guava seed ethanol extract in this investigation. The seeds of the malay apple were extracted using the maceration process using ethanol as the solvent. The antioxidant activity of the concentrated extract was then determined using the 1,1-Diphenyl-2-Picryhydrazyl (DPPH) method, which uses a small, simple, fast, and easy sample to activate the antioxidant activity of natural substances. This study took place between April and May of 2022. The IC50 value was determined to be 3,511 ppm. The antioxidant activity in this study exhibits substantial antioxidant activity to fight free radicals, according to the IC50 value obtained.
ANALYSIS OF TOTAL PHENOLIC ON ETHANOL EXTRACT OF MALAY APPLE SEED (Syzygium malaccense (L.) Merr.& Perry) Rosa Devitria; Mega Elfia; Rio Dwi Andika
Ensiklopedia of Journal Vol 5, No 2 (2023): Volume 5 No. 2 Edisi 1 Januari 2023
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.323 KB) | DOI: 10.33559/eoj.v5i2.882

Abstract

Jambu Bol (Syzygium Malaccense) merupakan salah satu tanaman yang berpotensi sebagai antioksidan karena mengandung metabolit sekunder hampir di seluruh bagian tanamannya, seperti daging buahnya, namun pada kali ini, peneliti hanya menjadikan biji jambu bol saja sebagai objek penelitian. Salah satu metabolit sekunder yang terkandung pada  jambu bol ini yakni fenolik.Fenolik ini merupakan senyawa bahan alam yang cukup luas penggunaannya pada saat ini, dan juga fenolik merupakan kelompok senyawa terbesar yang berperan sebagai antioksidan alami pada tanaman. Penelitian ini bertujuan untuk menentukan apakah di dalam biji jambu bol (Syzygium malaccense) terkandung senyawa fenolik dan juga menentukan kandungan total fenolik dari ekstrak etanol biji jambu bol dengan metode spektrofotometri UV-Visible. Kadar total fenolik  dinyatakan dalam gallic acid equivalent (GAE). Jenis penelitian yang digunakan adalah secara kualitatif dan kuantitatif. Hasil analisis kualitatif menunjukkan bahwa biji jambu bol (Syzygium malaccense) mengandung senyawa fenolik, kemudian dilanjutkan dengan analisis kuantitatif. Hasil analisis menunjukkan bahwa kadar total fenolik ekstrak etanol biji jambu bol sebesar15,488 mgGAE/g.Kata kunci: Fenolik, Spektrofotometer UV-Vis,Syzygium malaccense
UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL BIJI BUAH PARE (Momordica Charantia) PADA MENCIT (Mus Musculus) Devitria, Rosa; Elfia, Mega; Yesti, Yulia; Rafa, Huda Nur
Ensiklopedia of Journal Vol 6, No 2 (2024): Vol. 6 No. 2 Edisi 2 Januari 2024
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v6i2.2139

Abstract

Diabetes Mellitus (DM) is defined as a disease or chronic metabolic disorder with multiple etiologies characterized by high blood sugar levels accompanied by disturbances in carbohydrate, lipid and protein metabolism as a result of insulin insufficiency. The use of traditional medicine in Indonesia is currently in great demand by the public, one type of plant that is widely used as traditional medicine is bitter melon (Momordica charantia). The ingredients of bitter melon which are useful for lowering blood glucose are charantin, insulin polypeptide-P, and lectins. This study aims to determine the antidiabetic activity of the ethanol extract of bitter melon seeds (Momordica charantia) against male mice (Mus musculus) charged with 50% glucose solution. Tests for antidiabetic activity in mice were carried out in 5 treatment groups, namely the negative control group (1% w/v Na-CMC), the positive control group (0.01% Glibenclamide suspension), the first test group (50 mg/kg BW of bitter melon seed extract). , Test Group II (150 mg/kgBB ethanol extract of bitter melon seeds), and Test Group III (250 mg/kgBB ethanol extract of bitter melon seeds). The results of the study were analyzed using the One-Way ANOVA statistical test. The results showed that the ethanol extract of bitter gourd seeds was able to inhibit glucose absorption where the greatest total inhibition occurred at a dose of 250 mg/kg, namely 118 mg/dL, then at a dose of 150 mg/kg, namely 88 mg/dL, and finally at a dose of 50 mg/kg, which is 116 mg/dL.Keywords: Bitter melon fruit seeds (Momordica charantia), antidiabetic, male mice (Mus musculus)
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL YANG MENGANDUNG EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J. R & G. Forst) DENGAN MENGGUNAKAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Sidoretno, Wahyu Margi; Devitria, Rosa; Sepriyani, Harni
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2796

Abstract

Matoa (Pometia pinnata J.R & J. G. Forster) is one of the plants that can be used for traditional medicine. Based on several studies, it is stated that the ethanolic extract of matoa leaves has good antioxidant activity. This study aims to determine the antioxidant activity of gel preparations from the ethanolic extract of matoa (Pometia pinnata) leaves. Matoa leaf extract (Pometia pinnata) was prepared using maceration method with 96% ethanol as solvent. Then the extract was formulated into a gel with 4 formulations, namely F0 (no matoa leaf extract), FI (with 0.1% matoa leaf ethanol extract), FII (with 0.3% matoa leaf extract), FIII (with ethanol leaf matoa by 0.5%). Furthermore, the antioxidant activity test was carried out on the gel samples using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) spectrophotometrically at a wavelength of 515 nm. The results of the antioxidant activity test showed that the percentage of inhibition of the 96% ethanol extract of matoa leaf (Pometia pinnata) was F0 40.34%, FI 55.187%, FII 61.703%, FIII 27.969%, and the percentage inhibition of vitamin C was 178.947%. So it can be said that the matoa leaf extract gel has antioxidant activity.
Analisis Kadar Total Fenolik Sediaan Teh Herbal Dari Kulit Buah Naga Super Merah (Selenicereus costaricensis) Dan Daun MINT (Mentha piperita L.) Yesti, Yulia; Fadhilah, Nailatul; Putra, Billy Harnaldo; Elfia, Mega; Devitria, Rosa; Gusriyani, Sri; Saputra, Harry Ade
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 3 No 2 (2024): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v3i2.1526

Abstract

Teh herbal atau herbal tea merupakan salah satu produk minuman campuran teh dan tanaman herbal yang memiliki khasiat dalam membantu pengobatan suatu penyakit atau sebagai penyegar. Teh herbal dapat dikonsumsi sebagai minuman sehat yang praktis untuk menjaga kesehatan. Sampel yang digunakan dalam penelitian ini adalah kulit buah naga super merah (Selenicereus costaricensis) yang diperoleh dari Kecamatan Ampek Angkek, Kabupaten Agam dan daun mint (Mentha piperita L.) yang diperoleh dari Kecamatan Ampek Koto, Kabupaten Agam, Potensi kulit buah naga super merah sebagai obat masih belum termanfaatkan dengan optimal. Salah satu cara untuk mendapatkan khasiatnya, yaitu kulit buah naga super merah (Selenicereus costaricensis) atau super red ini dikonsumsikan dengan daun mint (Mentha piperita L.) dalam bentuk kering yang kemudian diseduh dan diminum. Minuman ini biasanya disebut dengan teh herbal. Tujuan penelitian adalah mengetahui kadar total fenolik terbaik dari 5 variasi komposisi pada sediaan herbal kulit buah naga super merah dan daun mint. Variasi komposisi kulit buah naga super merah dengan daun mint adalah 9:1; 8:2; 7:3; 6:4; 5:5. Uji kadar total fenolik dilakukan menggunakan metoda spektrofotometri UV-Vis. Kadar total fenolik dari 5 variasi komposisi sediaan teh hebal kulit buah naga super merah dan daun mint dengan kadar total fenolik tertinggi pada formulasi 5:5 dengan nilai total kadar fenolik yaitu 0,255 %. Dari hasil penelitian ini dapat disimpulkan bahwa semakin sedikit kulit buah naga super merah dan semakin banyak daun mint maka semakin tinggi kadar total fenolik. Untuk peneliti selanjutnya disarankan menggunakan metoda freeze drying untuk pengeringan agar tidak merusak senyawa yang terdapat dalam sampel.
Analisis Kadar Air dan Kadar Protein pada Surimi Ikan Patin (Pangasius, sp) dengan Variasi Pencucian dan Penambahan Tepung Sagu Rosa Devitria; Harni Sepriyani
Jurnal Sains dan Kesehatan Vol. 3 No. 1 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i1.215

Abstract

Patin Fish (Pangasius, SP), is one type of freshwater fish found in rivers in Riau Province. Patin fish is a source of high quality food, but it is a highly perishable food. Therefore, to overcome this need a way of preservation and processing that can maintain durability and not reduce the nutritional value that is by making surimi. In this research, the basic ingredients of patin fish are made with sago flour. Sago flour has different physical properties from tapioka flour and wheat flour so that it will increase the ability to from in surimi. Surimi is made with washing variations and added sago four. The results of this research were obtained from testing the chemical characteristics of surimi which were made with washing variations and obtained sago flour. The lowest and highest water conten of surimi is 52.1832% and 75.7656%. The lowest and highest protein content of surimi is 8.6631 % and 17.5487%.
Gambaran Kadar Kolesterol Total Pada Lansia Di Puskesmas Rumbai Fatma; Eli Yusrita; Rosa Devitria; Mega Elfia; Mentari Dwi Anggraini
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 2 (2024): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i2.2025

Abstract

Seiring dengan berkembangnya zaman dan modernisasi yang terus terjadi menyebabkan perubahan pola dan gaya hidup masyarakat terutama di daerah perkotaan. Kadar kolesterol total yang tinggi akan membentuk asterosklerosis yang dapat menyebabkan hipertensi dan penyumbatan pembuluh darah otak, jantung dan pembuluh darah tungkai. Sedangkan penyumbatan pada pembuluh darah tungkai dapat menyebabkan penyakit pembuluh darah tepi. Keadaan ini sering terjadi pada kaki yang dapat menimbulkan rasa nyeri, kram. Beberapa penyebab kolesterol berlebih yaitu obesitas, kurang bergerak, umur dan jenis kelamin, merokok, sejarah keluarga pada dan pola makan sehari-hari. Kadar kolesterol banyak diderita oleh para lansia itu dikarenakan faktor usia yang semakin lama badan akan semakin malas untuk di gerakkan, sehingga kolesterol di dalam tubuh menumpuk kedalam hati, oleh sebab itu dibutuhkan gerakan yang seimbang antar pola makanan dan olahraga agar para lansia terhindar dari kolesetrol berlebih. . Tujuan dari penelitian ini adalah untuk mengetahui bagimana gambaran kadar kolesterol total lansia di puskesmas rumbai. Metode yang digunakan pada penelitian ini adalah metode POCT (Point Of Care Testing). Penelitian ini merupakan penelitian deskriptif. .Hasil pemeriksaan secara langsung menggunakan alat Easy Touch GCU dapat diketahui dari 30 responden, terdapat sebanyak 6 orang (20%) memiliki kadar kolesterol normal, 12 orang (40%) memiliki kadar kolesterol sedang, dan 12 orang (40%) memiliki kadar kolesterol total tinggi. Nilai rerata dari data hasil keseluruhan kadar kolestrol total pada lansia di Puskesmas Rumbai adalah 231.23 mg/dl.
ANALISIS KADAR TOTAL FLAVONOID, ALKALOID SAPONIN, DAN TANNIN EKSTRAK BIJI JAMBU BOL (Syzygium Malaccense L) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Devitria, Rosa; Elfia, Mega; Yesti, Yulia; Astuti Sari, Winda
Ensiklopedia of Journal Vol 7, No 2 (2025): Vol. 7 No. 2 Edisi 1 Januari 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i2.2792

Abstract

Indonesia is one of the world's island nations with high biodiversity of flora and fauna. The country's strategic geographical position is one of the factors contributing to its rich biodiversity. The global agreements on the disclosure and sustainable utilization of biodiversity for human needs are increasingly prevalent. Guava is rich in fiber, calcium, phosphorus, vitamin A, thiamine, riboflavin, ascorbic acid, and niacin. Although there is no medical research yet, Guava is believed to help alleviate constipation, diabetes, cough, headaches, and inflammation of the respiratory mucosa. Meanwhile, its seeds, bark, and leaves possess dynamic properties and have effects on blood pressure and respiration. To determine the properties of compounds contained in guava seed extract. This research uses quantitative and qualitative methods. The results of this research show that guava seeds have total flavonoid levels of 1.4008%, saponins 9.3363%, tannins 1.2703%, and alkaloids 1.8490%. The conclusion is that guava seeds contain positive secondary metabolite compounds including flavonoids, alkaloids, tannins and saponins. Keywords: Guava seeds, secondary metabolite compounds
GAMBARAN KADAR ASAM URAT WANITA MENOPAUSE YANG MENGKONSUMSI AIR PUTIH 2 LITER/HARI Pratiwi Irawan, Mega; Devitria, Rosa; Maulana, Ervita Ika; Atthahirah, Luthfiah
Ensiklopedia of Journal Vol 7, No 4 (2025): Vol. 7 No. 4 Edisi 1 Juli 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i4.3295

Abstract

Uric acid is the end product of purine metabolism that occurs in the body. Increased uric acid levels are more common in men, while in women, uric acid levels tend to be normal and will increase after entering menopause. This is because women have more estrogen, which is uricosuric, which triggers the excretion of more uric acid through urine. Uric acid levels can be lowered by consuming water because water can dilute and dissolve uric acid, making it easier for the kidneys to excrete uric acid from the body through urine. This study aims to determine the uric acid levels of postmenopausal women who consume 2 liters of water per day. This research uses cross sectional method. In this study, 23 menopausal women respondents in RT.001 Simpang Fixed Darul Ichsan Village were asked to consume 2 liters of water/day for 2 weeks. The results showed that the average uric acid level before consuming 2 liters of water/day was 6.587 ± 0.3266 mg/dL, while after consuming 2 liters of water it was 5.013 ± 0.7594 mg/dL. The results of the dependent t test were found to be significant, namely P value 0.000 0.05. This shows that there is a significant difference in uric acid levels in postmenopausal women before and after consuming 2 liters of water/day. From the research that has been done, it can be concluded that there is a significant difference between uric acid levels in menopausal women before and after consuming 2 liters of water/day.Keywords: Uric Acid, Menopause, Water
PENAMBAHAN TEPUNG KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) SEBAGAI SUMBER ANTIOKSIDAN PADA MAKANAN SEREAL Fatma, Fatma; Devitria, Rosa; Putri, Rahayu Nadia; Elfia, Mega; Yesti, Yulia
Ensiklopedia of Journal Vol 7, No 4 (2025): Vol. 7 No. 4 Edisi 1 Juli 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i4.3212

Abstract

Dragon fruit is one of the plants that has a high antioxidant content. Consumption of red dragon fruit only utilizes the fruit, while the skin waste which amounts to 30-35% of the fruit weight is underutilized. This study aims to determine whether the addition of red dragon fruit peel flour in cereal foods can increase antioxidant content using the DPPH (2,2-diphenyl-1-1-picrylhydrazyl) method. The inhibition power against oxidation through the antioxidant content test of red dragon fruit peel flour is 50.84%, and the inhibition power against oxidation obtained through the antioxidant content test of red dragon fruit peel flour and cereal is 25.83%. The sensory test results conducted on the taste test of 20 untrained panelists proved that the red dragon fruit peel flour could be well received by the panelists. The antioxidant inhibition level which is not too high with a value of 51% provides an opportunity for red dragon fruit peel as a natural antioxidant ingredient in food. The test results of the addition of red dragon fruit peel flour still have potential as a food additive that contains antioxidants and can be well received by people. Keywords: Dragon Fruit, Antioxidants, Cereals
Co-Authors Amanda Dwinta Harianti Astuti Sari, Winda Atthahirah, Luthfiah Billy Harnaldo Putra, Dini Fatmi, Dini Fatmi Eli Yusrita Eli Yusrita Elsa Mega Dwi Putri Fatma Fatma Fatma Fatma Febrianita, Yulia Fitria Desrita Sari Gusriyani, Sri Harni - Sepryani Harni Sepriyani Harni Sepriyani Harni Sepryani Harni Sepryani Harni Sepryani Harry Ade Saputra Hartati, Seri Larasari Putri Liza Trisnawati Luluk Elvitaria Manisha Tri Cahyani Maulana, Ervita Ika Mega Elfia Mega Pratiwi Irawan Mentari Dwi Anggraini Nadila Pratiwi Utami Nailatul Fadhilah Putri, Rahayu Nadia Rafa, Huda Nur Rio Dwi Andika Sepriyani, Harni Sepryani, Harni Sepryani, Harni - Sidoretno, Wahyu Margi Siti Juariah Siti Juariah Siti Juariah Sri Restu Ningsih Sukri Susi Endrini Wahyu Margi Sidoretno Ynisa Yulan Sarwis Yowantyano Dwiki Riaunanda Yulia Yesti, Yulia