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Correlation between Length-to-width Ratio of Gallbladder and Gamma-glutamyl Transferase Value in Biliary Atresia Elmanar, Ryan; Violetta, Lenny; Setiawati, Rosy
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

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Abstract

Biliary atresia represents one of the most prevalent etiologies for neonatal cholestasis. Unmanaged biliary atresia can be fatal. Ultrasonography is the primary diagnostic test because it's accurate, cost-effective, and available. Various ultrasound findings can assist in diagnosing biliary atresia; the length-to-width ratio of the gallbladder is a particularly advantageous method, offering a short examination time, objectivity, and ease of use, with an accuracy rate of 78.9%. In cases with unconventional ultrasound findings, gamma-glutamyl transferase is believed to be able to complete the diagnostic process with an accuracy rate of up to 80%. The optimal cut-off value differs between studies, making it challenging to use as a benchmark for biliary atresia detection. In this study, researchers aim to further investigate the relationship between length-to-width ratio and gamma-glutamyl transferase in cases of biliary atresia, compared to the liver biopsy results in these patients and the optimal cut-off. This study employed an observational analytic approach with a retrospective design. The sample population consisted of all patients with neonatal cholestasis who underwent laboratory and ultrasonographic examinations at Dr. Soetomo Academic General Hospital Surabaya between 2019 and 2023. The study population comprised 82 patients. A significant relationship (p-value<0.001) was observed between the length-to-width ratio of the gallbladder and biliary atresia, as well as between gamma-glutamyl transferase and biliary atresia (area under the curve: 0.7–0.8). However, the analysis between the length-to-width ratio of the gallbladder and the value of gamma-glutamyl transferase showed p-value=0.066, which means no significant relationship was observed between the length-to-width ratio and gamma-glutamyl transferase. DOI: https://doi.org/10.29313/gmhc.v12i3.14170
The Role of Lumbar CT Scan Anthropometric Parameters to Predict the Height of Indonesian Adults Afriliani, Nurmilia; Setiawati, Rosy; Violetta, Lenny
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14141

Abstract

Anthropometry, the study of human body measurements, is crucial in estimating stature, which is valuable in medical research, forensic science, anthropology, and ergonomic design. While various methods exist for estimating stature, lumbar spine measurements make a significant contribution to this estimation. This study aimed to analyze the relationship between lumbar spine dimensions and stature in the Indonesian population using three-dimensional computed tomography (3D CT) scan data. This analytical observational study, employing a cross-sectional approach, was conducted at the Department of Radiology, Dr. Soetomo General Academic Hospital, Surabaya, from August to September 2023. The key measurements included heights of the posterior, anterior, and central vertebral bodies from lumbar 1 to lumbar 5 (L1 to L5), transverse pedicle diameter, pedicle axis length, vertical pedicle diameter, and overall stature. The study included 66 subjects (30 males and 36 females). Males had an average height of 165.86 cm, while females had an average height of 155.85 cm. Significant gender differences were observed in heights of the posterior vertebral body (HPVB), heights of the central vertebral body (HCVB), and pedicle axis length (PAL) measurements. HPVB of L1 can be used as a predictor of height in females (p<0.001), whereas PAL of L5 can be used as a predictor of height in males (p=0.006). Lumbar spine dimensions measured using 3D CT scans provide reliable stature predictions, with specific measurements such as HPVB from L1 in females and PAL from L5 in males showing high accuracy. These findings support the development of population-specific anthropometric tools and enhance understanding of factors influencing stature in Indonesia.
Case Report: Survival of A Coronavirus Disease-2019 (Covid-19) Patient with Acute Respiratory Distress Syndrome (ARDS) in Dr. Soetomo Hospital, Surabaya, Indonesia Soedarsono, Soedarsono; Semedi, Bambang Pudjo; Setiawati, Rosy; Meliana, Resti Yudhawati; Kusmiati, Tutik; Permatasari, Ariani; Bakhtiar, Arief; Syafa'ah, Irmi; Indrawanto, Dwi Wahyu
Folia Medica Indonesiana Vol. 56, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China has spread rapidly in multiple countries of the world and has become a pandemic. Currently, there is no vaccine or specific antiviral for COVID-19. A study reported 7.3% of critical patients admitted to ICU, 71% of them required mechanical ventilation, and 38.5% of them were survived. Herein, we reported a 54 year old man with Acute Respiratory Distress Syndrome (ARDS) of COVID-19 who survived the disease. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasopharyngeal and oropharingeal swabs were positive for SARS-CoV-2. Diagnosis of ARDS was also according to clinical symptoms, laboratory, chest radiograph, and chest CT scan. Alcaligenes faecalis and Candida albicans were also identified from sputum culture. Treatment for this patient was causal and supportive therapy, including antibiotic, antiviral, and antifungal therapy according to the culture results, fluid resuscitation, and oxygen supply from the mechanical ventilator. This patient was survived and discharged on hospital day-29. A fibrosis in parenchyma pulmonary and sensory peripheral neuropathy occurred after survived from ARDS. Monitoring of clinical, laboratory, and chest radiograph were continued after the patient discharged from the hospital. This case highlights the importance of early diagnosis and effective treatment to the care of COVID-19 patient.
Epiphyseal Closure Time of Radius and Ulna Bones of the Proximal Section Lio, Tiara Mayang Pratiwi; Koesbardiati, Toetik; Yudianto, Achmad; Setiawati, Rosy
Folia Medica Indonesiana Vol. 54, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Accurate determination of age is important in the legal process; when a person's age is unknown or must be authenticated, a forensic age identification method must be applied. One of such methods is to assess the epiphyseal closure on the bone through radiological examination. The main problem associated with the use of this method is the relevance of the reference population provided because epiphyseal closure is influenced by genetics and nutrition. This method needs data to represent each population. Radiological examination of elbow bones of 30 male patients aged 11-30 years and 18 female patients aged 14-28 years in Dr. Soetomo Hospital, Surabaya from January to April 2016 was carried out to determine the time of epiphyseal closure of the radius and ulna distal section. This was cross-sectional descriptive study. In conclusion, epiphyseal closure of proximal radius and ulna is complete at age 16 in males and 14 in females.
Secondary Osteosarcoma in Paget Disease: A Rare Case Report Putri, Felicia Ivana; Setiawati, Rosy
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i12.62706

Abstract

Osteosarcoma is a malignant bone tumor, which can develop with the formation of immature bone or osteoid. It most commonly affects in children and adolescents, while its occurrence in elderly patients is relatively rare. In elderly patients, osteosarcoma can arise with paget’s disease, a condition characterized by abnormal bone remodeling. This report presents an unusual case of osteosarcoma in elderly patients highlighting the importance of radiological and biopsy evaluation in establishing the diagnosis. A 66-year-old man presented with a history of a lump on the right lower extremity, present for the past ten years and progressively enlarging over the last six months. patient experienced pain both at rest and during movement. There was no history of trauma, falls, comorbidities or family history that were associated with disease. Plain radiographs, MRI, and needle biopsy were performed. Imaging studies demonstrated bone destruction, periosteal reaction, soft tissue extension, and matrix ossification which are characteristic findings of osteosarcoma. Pathological examination identified a clusters and dispersed anaplastic cells with round-to-oval, pleomorphic, and hyperchromatic nuclei. Incidence of osteosarcoma in elderly patients is rare and show a poorer prognosis than do children and adolescent patients. In this age group, osteosarcoma often arises as a secondary malignancy. Conditions such as Paget’s disease or prior malignancies are known contributors. Several predisposing factors for adult-onset osteosarcoma have been identified, including underlying genetic syndromes, benign bone lesions, and a history of radiation therapy or chemotherapy. Early diagnosis in older individuals is important often challenging due to atypical presentations, often leading to misdiagnosis or delayed recognition. In elderly patients, bone tumors require careful diagnostic workup. Plain radiography play central role in initial evaluation, MRI delineates soft tissue involvement and metastatic spread, and histopathology confirms the diagnosis.