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All Journal Bioeducation Journal BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan BIO-SITE |BIOLOGI Sains Terapan Jurnal Pendidikan Fisika Jurnal Penelitian Pendidikan IPA (JPPIPA) BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Jurnal Basicedu International Journal of Educational Dynamics (IJEDS) Atrium Pendidikan Biologi BiosciED: Journal of Biological Science and Education TROPICAL GENETICS International Journal of Humanities Education and Social Sciences Tropical Genetics Jurnal Serambi Biologi Biodik: Jurnal Ilmiah Pendidikan Biologi
Yuni Ahda
Universitas Negeri Padang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Social Sciences Other

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The Prediction of the Interaction Genistein and Daidzein Compounds on ESR2 Expression by Molecular Docking Quratul Akyuni; Dwi Hilda Putri; Yuni Ahda
Jurnal Serambi Biologi Vol. 8 No. 1 (2023): Jurnal Serambi Biologi
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aims: Estrogen is known to have various roles in the body. ESR2 is an estrogen receptor expressing estrogen receptor beta (ERβ). ERβ is expressed in normal breast epithelial cells as well as in various other tissues such as the uterus, ovary, prostate and brain, and breast cancer cells. One plant that is thought to have the potential to increase ERβ expression is soybean (Glycine max). Soybean plants contain very important phytochemicals, so they are widely used in the food industry as supplements and included in drug formulations. Methods: This type of research is descriptive research conducted using in silico method through the molecular docking approach. The metabolites used were genistein and daidzein for the target protein ESR 2 (PDB ID: 1QKM). Result: The docking results showed that the binding affinity value of the metabolites genistein, daidzein, and native ligand was -9.7 kcal/mol. The RMSD value obtained from LigRMSD was 0.40 with very similar visualization between the ligand test before and after docking. Main Conclusion: The conclusion of this study is that the metabolites of genistein and daidzein are predicted to have the ability to increase ESR2 expression in the human body.
Aspect Analysis in Higher Order Thinking Skills on the Evaluation Instrument of Protist Topic for the Grade 10 Senior Highschool Students Riri Rahmadani Putri; Yuni Ahda; Rahmawati D
BIODIK Vol. 4 No. 1 (2018): Juni 2018
Publisher : Program Studi Pendidikan Biologi FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/bio.v4i1.5504

Abstract

Higher order thinking skills are essential for student future. The 2013 Curriculum demands the existence of an evaluation instrument to train student higher order thinking, not only the thinking skill in the lower cognitive domain, but also in a higher domain. One of the efforts to enhance higher order thinking skills is to engage students with the questions integrated by cognitive C4-C6. This study analysed aspects of higher order thinking in an evaluation instrument. This study used descriptive method by collecting evaluation instrument data used by teachers to evaluate a learning process. Evaluation instruments used by teachers at schools are still in the C1-C3 cognitive level (C1 47%, C2 47%, and C3 6%), the evaluation instruments are not eligible according to the standard applied. The skills demanded by the Fundamental Competency of the 2013 Curriculum. Higher order thinking skills of students are still relatively low, with the percentage mean of 52.03%. The low cognitive level obtained in the evaluation instrument used by the teachers is the reason of the low thinking level of the students.
Development of Teaching Problem Learning Model and Ability to Sharing Ability to Biological Competence Class VII Students of MTsN Pakan Rabaa Yulia Ratna Sari; Yuni Ahda; Ramadhan Sumarmin
BIODIK Vol. 4 No. 1 (2018): Juni 2018
Publisher : Program Studi Pendidikan Biologi FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/bio.v4i1.5507

Abstract

The lack of student understanding on the topic of Biology presented by teacher may lead them towards a low achievement. This case could be seen from the low students’ average learning outcomes in the 7th grade Biology at MTsN Pakan Rabaa according to Minimum Completeness Criteria ( MCC ). One of the reasons is the traditional method of question and answer applied by the teachers. Biology teachers only emphasizes learning on cognitive aspects. The low level of student learning outcomes are also determined by the students’ prerequisite knowledge. In order to solve this problem, the use of Problem Based Learning and initial ability learning model was applied. The purpose of this study is to evaluate the effect of Problem Based Learning and Initial Ability learning models based on the competence of the student learning styles of 7th Grade Biology at MTsN Pakan Rabaa in 2014/2015 academic year. This research applied quasi experiment which used the static group comparison design. The population was all of the 7th grade MTsN Pakan Rabaa students in academic year of 2014/2015. Sampling technique used was saturated sampling technique and the participants for the experimental class were class VII A, with VII B as the control class. The research findings showed that (1) the students’ cognitive domain was significantly affected after the implementation of problem based learning model, except for those with high cognitive domain levels. (2) The students’ cognitive domain were improved significantly for both students with high and low ability. (3) The students’ psychomotor domain ability were improved significantly for both students with high and low ability (4) there was no interaction between the model of problem-based learning with the initial ability of students to learn biology cognitive competence of students.
Effect of Ethanolic Extract of Avocado (Persea americana Mill.) Seed on the Testis Histology (Mus musculus l.) Induced Monosodium Glutamate (MSG) Yusni Atifah; Dwi Junita Zega; Yuni Ahda; Siska Alicia Farma
BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Vol 12, No 2 (2024): JURNAL BIOTIK
Publisher : Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/biotik.v12i2.24419

Abstract

Monosodium Glutamate (MSG) is a substance that is able to produce free radicals such as ROS (Reactive Oxygen Species), which can cause oxidative stress in the body and damage reproductive organs such as the testes. The purpose of this study was to determine the effect of avocado seed ethanol extract (Persea americana Mill.) on the histology of the testes of mice (Mus musculus L.) induced monosodium glutamate (MSG). This research is an experimental study that was conducted in October 2023 – January 2024 at Biology Laboratory, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang. The design used is a Complete Randomized Design (CRD) with 4 treatments and 6 repeats. The data obtained were analyzed using the ANOVA test (Analysis of variance) using the SPSS 23 application. The results showed that the administration of avocado seed ethanol extract showed a noticeable effect on the diameter of the testes of male mice exposed to MSG. However, it showed no noticeable influence on testicular weight, seminiferous tubule diameter and Leydig cell count. Ethanol extract avocado seed dose 0.84 mg /g body weight / day (P1) was able to improve the diameter of mice testes that had been induced MSGKeyword: Avocado seed extract, Histology of testis, Mice, MSG
Penyakit Hirschsprung di Indonesia: Faktor Potensial yang Berkontribusi dan Analisis Silsilah Yuni Ahda; Khairunnisa; Zuhrah Taufiqa; Diana Lyrawati; Risa Ukhti Muslima
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9301

Abstract

Hirschsprung’s disease (HD) has a complex origin involving genetic factors. While HD cases have been documented in Indonesia, the genetic inheritance is unexplored. This study aims to update HD in Indonesia, determine the inheritance pattern through pedigree analysis, and identify the non-genetic factors contributing to HD, including parental demographics and maternal aspects. A cross-sectional survey was conducted with 87 respondents across Indonesia. The results revealed a male-to-female incidence ratio of 1.90:1, with the ultra-short segment being the most common type (75.86%), and familial cases accounted for 8%. Seventeen patients exhibited other congenital abnormalities, with pneumonia, redundant colon, and cardiac defect as the highest cases. Over 70% of the parents were aged 20-35 and had relatively high education and income levels. Notably, nearly half of the mothers experienced food aversion in the first trimester (n=38) and frequently consumed fast or instant food during pregnancy (n=33). The study confirmed that HD follows an autosomal recessive inheritance pattern. These findings emphasize the role of genetic inheritance in incidents of HD, which is valuable for developing early detection strategies and providing genetic counseling for at-risk families. Maternal lifestyle factors may play a role in the development of HD, which needs further investigation.
The Impact of Problem-Based Learning on Science Learning to Improve Students' Critical Thinking and Problem-Solving Skills: A Meta-Analysis Nurul Aripin; Festiyed; Yerimadesi; Heffi Alberida; Yuni Ahda; Fatni Mufit
Jurnal Penelitian Pendidikan IPA Vol 11 No 6 (2025): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i6.10051

Abstract

This meta-analysis investigates the effectiveness of the Problem-Based Learning (PBL) model in enhancing students' critical thinking and problem-solving skills in science education. A total of 42 peer-reviewed articles published between 2020 and 2024 were analyzed, covering diverse educational levels and scientific disciplines. The analysis revealed a large average effect size (ES = 0.798; 95% CI: 0.782–0.813), indicating a strong positive impact of PBL. The low standard error (SE = 0.043–0.060) reflects high estimation precision. Statistical tests, including funnel plot symmetry, Trim-and-Fill analysis (p = 0.991), and Egger’s regression test (p = 0.947), confirm the absence of significant publication bias. Moreover, residual heterogeneity was minimal (τ² = 0.000), validating the appropriateness of the fixed-effects model. These findings provide robust empirical evidence that PBL is consistently effective across various contexts in improving students’ 21st-century competencies. The study offers meaningful implications for educators and policymakers in designing science learning strategies that foster higher-order thinking skills.
The Development of Inquiry-Based LKPD to Enhance Critical Thinking Skills in Science learning at Elementary Schools Sisri Wahyuni; Yeni Nurpatri; Festiyed; Yerimadesi; Heffi Alberida; Yuni Ahda
Jurnal Penelitian Pendidikan IPA Vol 11 No 3 (2025): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i3.10157

Abstract

This research is motivated by the development of LKPD (Student Worksheet) for enhancing critical thinking skills of elementary school students. The LKPD used has not yet captured the students' attention. The LKPD has not been able to improve students' learning motivation because it does not align with their learning styles. LKPD serves as teaching material used by teachers to facilitate the delivery of content and achieve learning objectives. This study aims to develop LKPD and assess its validity using the Inquiry model to improve critical thinking skills in Science education about the conservation of natural resources in the 4th-grade class. The type of research used is research and development (R&D), employing the 4-D model. This model consists of four development stages: define, design, development, and dissemination. Based on the results of the validation of LKPD using the Inquiry model to enhance critical thinking skills, the LKPD is deemed feasible for use. The material aspect validation result was 85.41% (valid), the design aspect validation result was 86.53% (valid), and the language aspect validation result was 94.44% (very valid). Therefore, the LKPD using the Inquiry model to improve critical thinking skills is valid.
Co-Authors Abdul Razak Achyar, Afifatul Ahmad Saleh Ali Amran Ali Imran Annisa Irna Putri Atifah, Yusni Berry Devanda Chakra Wirangga Diana Lyrawati Dinelti Fitria Dwi Hilda Putri Dwi Junita Zega Eldyana Rahayu Putri Fatni Mufit Febri Yanti Festiyed Festiyed Festiyed Fitri Arsih Fitria, Yanti Heffi Alberida Helendra . Husnin Nahry Yarza Indra Hartanto Khairunnisa Kiki Mulyani Lufri Lufri Mades Fifendi Muhammad Ikbal Nurul Aripin Nurul Aulia Rahmi Putri, Riri Rahmadani Quratul Akyuni Rahmawati Darussyamsu Ramadhan Sumarmin Ramadhan Sumarmin Ramadhan Sumarmin Rani Dwi Suci Hd Putri Relsas Yogica, Relsas Reny Novita Sari Rika Andima Risa Ukhti Muslima S. Syamsurizal Selaras, Ganda Hijrah Sisri Wahyuni Taufiqa, Zuhrah Titis Wulandari Tri Putri Wahyuni Velina Salsabil windi maualana putri Yeni Nurpatri Yerimadesi Yerimadesi Yerimadesi Yolanda Ruhul Azomi Yul Ifda Tanjung Yulia Ratna Sari Zuhratul Mardhiyah Amir