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All Journal Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Jurnal Pemberdayaan Masyarakat Universitas Al Azhar Indonesia Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Sains Alami (Known Nature) Berkala Penelitian Hayati KOPEMAS Jurnal Ragam Pengabdian
Ari Hayati
Biologi FMIPA UNISMA
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Effect of Tea and Mango Mistletoe Extract as Dietary Adjuvant on Triglyceride in Wistar Rats Tania Putri Nur Yasinta; Nour Athiroh Abdoes Sjakoer; Ari Hayati
Jurnal Ragam Pengabdian Vol. 3 No. 1 (Spesial Issue) (2026): "Dharma Samudera"
Publisher : Lembaga Teewan Journal Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62710/4q3pmt31

Abstract

The increasing prevalence of obesity in Indonesia has contributed to a rise in metabolic disorders, including hypertriglyceridemia, which is a major risk factor for cardiovascular and metabolic diseases. Therefore, safe and effective natural- based therapeutic alternatives are needed. This study aimed to evaluate the effect of a combined extract of tea mistletoe (Scurrula atropurpurea) and mango mistletoe (Dendrophthoe pentandra) leaves as a dietary adjuvant on serum triglyceride levels in male Wistar rats (Rattus norvegicus) induced with a high- fat diet. This experimental study employed a randomized pre-test post-test control group design with five groups: negative control, positive control (high-fat diet), and three treatment groups receiving the combined extract at doses of 50, 100, and 200 mg/kg body weight (n = 7 per group). The treatment was administered orally for 37 days. Serum triglyceride levels were measured using the Colorimetric Enzymatic Test (Glycerol Phosphate Oxidase method) and analyzed using one-way analysis of variance (ANOVA). The results demonstrated a statistically significant difference in triglyceride levels among the groups (p = 0.01024). The positive control group exhibited the highest mean triglyceride level, whereas administration of the combined mistletoe extract resulted in a reduction in triglyceride levels. The most pronounced decrease was observed in the group receiving 100 mg/kg body weight, which showed the lowest mean triglyceride level among the treatment groups. The hypolipidemic effect of the combined extract is presumed to be associated with the presence of bioactive compounds such as flavonoids and polyphenols, which possess antioxidant properties and play a role in lipid metabolism regulation. In conclusion, the combined extract of tea mistletoe and mango mistletoe has potential as a natural dietary adjuvant for lowering triglyceride levels and improving lipid profiles in conditions of high-fat diet–induced dyslipidemia.
Co-Authors Ahmad Baidarus Ahmad Mijwad Rajab Ahmad Taufiq Ainur Rasyid alfira khullatun ni'am Devi Sugiarto Dewi Rahayu Saraswati Dewi Vebriyanti Edi Santoso Elmi Zakiah Fahru Reyza Watimena Farah Aida Qotrun Nada Fernando H. Alvarizi Nurdin Fitria Fitria Garnis Mufarrohah Rohmah Gatra Ervi Jayanti Hasan Zayadi Hosnia Sari Husnul Hotimah Ibnu A. Bahri Ifadotul Lailatussholiha Ilnia Fadhil Indriani Rachman Saputri Istirochah Pujiwati Izzatul Bahriyah Kamiliatul Mufidah Khamidatul Ula Khoiratul Hasanah Khoiria Anisa Lailatul Maghfiroh Lutfi Niam Lutfiah sudarmaji Ma'rifatul As'adah Mai Suroh Mas Ajeng Wahyu Hidayah Miftahul Mukarromah Moch. Syamsuddin Mohamad Rizal A. Tupong Muhammad Bachri Mutawakkil Ashofat Nilam Firdausi Niqrisatut Thibab Nour Athiroh Abdoes Sjakoer Nubdatul Fikroh Nur Ainiah Nur ismalasari Nurul Jadid Mubarokati Nurul Qomariyah Nurvikrih Choliluddin Ghafur Rafida Azizah Retno wulandari Rina Fatmawati Rita Purwanti Rokha Illiyyin Siti Marirotuz Zahro' Siti Milatil Hasanah Siti Rahmah Tania Putri Nur Yasinta Tintrim Rahayu, Tintrim Tria Khotami Ayuba Wulan Dari Neng Gumiwang Yulia Pambayuning Tyas Yuliana Musrifatul Maula