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All Journal Journal of Food and Pharmaceutical Science Indonesian Journal of Tropical and Infectious Disease CERATA Jurnal Ilmu Farmasi ad-Dawaa : Journal of Pharmaceutical Sciences Community Empowerment Jurnal Farmasi Sains dan Praktis Urecol Journal. Part D: Applied Sciences Prosiding University Research Colloquium Journal of Food and Pharmaceutical Sciences MOTORIK CERATA Borneo Journal of Pharmacy
Agustina Styawan, Anita
Program Studi D3 Farmasi STIKES Muhammadiyah Klaten, Indonesia.
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Analisis Logam Merkuri (Hg) dalam Krim Pemutih Herbal Temulawak (Curcuma zanthorrhiza) dengan Metode Mercury Analyzer Anita Agustina Styawan; Lenny Apriyaningsih; Dwi Joko Yulianto
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.68

Abstract

Temulawak herbal whitening cream is one of the herbal whitening creams containing curcumin rhizome extract containing curcumin, demetoksikurkumin and bidemetoksikurkumin which can reduce hyperpigmentation (the skin becomes too dark). Mercury is a dangerous metal that in even small concentrations can be toxic. The use of mercury in whitening creams can cause a variety of things, ranging from changes in skin color which will eventually cause black spots on the skin, allergies, skin irritation and can be carcinogenic. The results of the study qualitatively indicated that sample A was positive containing mercury marked by an orange-red precipitate. Quantitatively, using Mercury Analyzer in sample A, the levels of mercury were 7,470.52 mg / kg or 7,470.52 ppm. The conclusions indicate that sample A is inappropriate or should not be used because it contains more than 1 mg / kg or 1 ppm of mercury.
Analisis Kandungan Asam Retinoat Pada Sediaan Krim Malam Yang Beredar Di Toko X Kota Klaten Dengan Spektrofotometri UV-Vis Yenni Kusuma Wardhani; Anita Agustina Styawan; Choril Hana Mustofa
CERATA Jurnal Ilmu Farmasi Vol 10 No 2 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i2.79

Abstract

Whitening cosmetics are cosmetics that contain an active whitening ingredient to brighten the skin. Retinoic acid is prohibited from being used in whitening creams because it can cause dry, burning, carcinogenic and teratogenic skin. The purpose of this study was to determine the levels of retinoic acid contained in night creams. The sample in this study were 5 night cream products circulating in Klaten City X Store. This study was conducted to determine the content of retinoic acid in night creams using thin layer chromatography (TLC). Five positive samples contained retinoic acid by giving dark green spots and the concentration was determined by UV-Vis spectrophotometry.The results of this study indicate that in 5 samples of night cream circulating in Store X in the City of Klaten all positive for retinoic acid, that is, the average for sample A was 0.021%; sample B 0.014%; sample C 0.016%; sample D 0.025% and sample E 0.023%.
Uji Stabilitas Formula Optimum Masker Gel Peel Off Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) Nurul Hidayati; Anita Agustina Styawan; Ida Naim Muslimah
CERATA Jurnal Ilmu Farmasi Vol 11 No 2 (2020): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v11i2.145

Abstract

Mahkota Dewa fruit (Phaleria macrocarpa (Scheff.) Boerl was effective as an anti-acne agent and an optimization formula of Mahkota Dewa fruit extractpeel off gel mask has been carried out but the stability test has not been carried out. This study aims to determine the stability of the optimum formula of Mahkota Dewa fruit extract (Phaleria macrocarpa (Scheff.) Boerl)peel off gel mask. The fruit simplicia of Mahkota Dewa was extracted by soxhletation with 70% ethanol. The thick extract is made into a peel off gel mask with 13.09%PVA and 2.97% HPMC. Stability tests were carried out in 3 cycles using the freeze and thaw method. The evaluations carried out included organoleptic, homogeneity, pH, viscosity, dispersibility, adhesion and drying time. Analyzed data by One Way Anova followed by the LSD (Least Significance Difference) test. The results showed that the peel off gel mask optimization formula stable in storage for 3 cycles which overall meet the requirements of physical properties. The preparation was brown with rose aroma, thick, homogeneous with a pH value of 6 ± 0 and a viscosity value of 400 ± 0. The results of the drying time and spreadability test showed no difference in all cycles. Although the results of the adhesion test showed a significant difference, it was still within the range of good adhesion values.
Penetapan Kadar Tanin Dari Bunga Telang (Clitoria ternatea L.) Secara Permanganometri Choiril Hana Mustofa; Anita Agustina Styawan; Nofia Putri Lestari
CERATA Jurnal Ilmu Farmasi Vol 12 No 2 (2021): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v12i2.234

Abstract

Telang flowers can be found thriving in watery areas in Indonesia, their purple flowers bloom throughout the year. Telang flowers have been studied to contain phenolic chemicals, flavonoids, anthocyanins, flavonol glycosides, kaempferol glycosides, quercetin glycosides, myristetin glycosides, terpenoids, flavonoids, tannins and steroids. Tannins are plant polyphenols that function to bind and precipitate proteins. In the world of tannin medicine serves to treat diarrhea, stop bleeding, and treat hemorrhoids. There are two main types of tannins namely condensed tannins and hydrolyzed tannins. The purpose of this study was to determine the tannin content in the extract of telang (Clitoria ternatea L.) flowers using the permanganometric method. Determination of tannin levels by permanganometric method. Permanganometry is a titration method using potassium permanganate, which is a strong oxidizing agent as a titrant. This property of KMnO4 is known as an auto-indicator. The result of the determination of the tannin content of the telang flower (Clitoria ternatea L.) by permanganometry was 13.86% b/b.
IDENTIFIKASI FLAVONOID PADA EKSTRAK ETANOL TEMU MANGGA (Curcuma mangga Val.) METODE EKSTRAKSI MASERASI DAN SOKLETASI SECARA KROMATOGRAFI LAPIS TIPIS Muchson Arrosyid; Anita Agustina Styawan; Selvi Candra Dewi; Rezyana Budi Syahputri
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i1.764

Abstract

Temu mangga merupakan salah satu keluarga Zingeberaceae, memiliki kandungan metabolit sekunder seperti flavonoid. Temu mangga (Curcuma mangga Val.) berkhasiat sebagai pereda sakit maag, diare, penghilang nyeri haid, mengobati jerawat dan bisul, serta menambah nafsu makan. Selain itu, temu mangga diduga memiliki aktivitas antioksidan karena adanya senyawa fenolik dan flavonoid yang terkandung di dalamnya. Tujuan penelitian ini untuk mengetahui jenis senyawa flavonoid yang terdapat dalam rimpang temu mangga (Curcuma mangga Val.). Ekstraksi dilakukan dua tahap yaitu tahap maserasi dan sokletasi tahap menggunakan pelarut yang sama yaitu etanol 70%. Identifikasi flavonoid ekstrak temu mangga dilakukan menggunakan metode kromatografi lapis tipis (KLT). Bercak lempeng yang memiliki harga Rf dan warna yang sama dengan deteksi awal yaitu kuning kehijauan menunjukkan hasil positif pada ekstrak metode sokletasi dan maserasi. Hasil identifikasi flavonoid pada ekstrak temu mangga (Curcuma mangga Val.) menunjukkan harga Rf ekstraksi secara maserasi sebanyak 0,53 dan hasil dari ekstraksi secara sokletasi sebanyak 0,82. Dari hasil tersebut menunjukkan bahwa terdapat perbedaan antara ekstraksi maserasi dan sokletasi.
Analisis Kadar Kafein Pada Biji Kopi Arabika (Coffea arabica L.) Varietas Lini S dari Perkebunan Kopi Banaran Dengan Metode Titrasi Bebas Air Wahyu Anasari; Anita Agustina Styawan; Mustofa, Hana; Muchson Arrosyid; Hendra Budiman
CERATA Jurnal Ilmu Farmasi Vol 15 No 1 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i1.1068

Abstract

Kopi arabika (Coffea arabica L.) Lini S merupakan salah satu yang paling populer di kawasan Asia Pasifik, khususnya di Indonesia. Biji kopi mengandung senyawa fenolik, asam klorogenat dan kafein. Kafein berkhasiat secara klinis menstimulasi susunan saraf pusat dengan menghilangkan rasa lelah, lapar dan kantuk. Tujuan penelitiam ini adalah untuk mengetahui kadar kafein dalam biji kopi arabika (Coffea arabica L.) varietas Lini S.Penelitian ini menggunakan cara observasional. Sampel yang digunakan sebanyak 300 gram serbuk kopi arabika (Coffea arabica L.) varietas Lini S dari perkebunan kopi Banaran. Ekstraksi dilakukan dengan metode refluks, kemudian diuji secara kualitatif menggunakan reaksi parry serta untuk mendapatkan konsentrasi kafein dengan cara Titrasi Bebas Air. Hasil uji kualitatif menggunakan reaksi parry yang positif kafein ditandai dengan warna hijau. Hasil uji kuantitatif dengan 3 kali replikasi diperoleh rata-rata kadar kafein pada biji kopi arabika sebesar 142,90 mg. Kadar kafein pada biji kopi arabika baik dikonsumsi untuk kesehatan karena nilai kadar tidak melebihi standar SNI yaitu 150 mg/hari.
Penetapan Kadar Flavonoid Total Ekstrak Etanol Buah Belimbing Wuluh (Averrhoa Bilimbi L.) Dengan Metode Spektrofotometri Uv-Vis Mustofa, Choiril Hana; Anita Agustina Styawan; Muchson Arrosyid; Hendra Budiman; Latifah, Anna
CERATA Jurnal Ilmu Farmasi Vol 15 No 2 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i2.1394

Abstract

Star fruit is a fruit that has been cultivated for a long time by Indonesian people. Star fruit plants consist of two types. Sweet starfruit and sour starfruit or wuluh, starfruit can be used as an anti-inflammatory and antioxidant. So further research needs to be carried out on testing the flavonoid content of ethanol extract of star fruit (Averrhoa bilimbi L.) using the UV-Vis spectrophotometric method. So that the potential for developing this plant as a medicinal ingredient for the prevention and treatment of various diseases can be increased. The aim of this study was to determine the levels of flavonoids in star fruit. This study used a sample of 3 kg of star fruit. Extraction using the maceration method with 96% ethanol solvent. Then analyzed qualitatively and quantitatively. The results of the research showed that the qualitative test with color reagents showed positive results of a brownish yellow color, there were flavonoid compounds in the star fruit, while the results of the quantitative test with UV- Vis spectophotometry showed levels of flavonoid compounds with an average of 0.4384% w/w or 4,384 mg/kg.
Co-Authors Abdul Rohman Anggit Khusnul Khotimah Anisa Dita Rahmawati Aristhasari Putri Arrosyid, Muchson Atun Yuliana Awal Prichatin Kusumadewi Choiril Hana Mustofa Choiril Hana Mustofa Choril Hana Mustofa Dayah Ainus Dian Irawati Dian Irawati Dwi Joko Yulianto Emerita Dyah Ayu Purwita Sari Faatin, Salsa Gandis Rohmanti Hari Widada, Hari Hendra Budiman Hendra Budiman Ida Naim Muslimah Khairiyah, Fatikhatun Nissa’ Khotimah, Anggit Khusnul Laelia Dwi Anggraini, Laelia Latifah, Anna Lenny Apriyaningsih Muchson Arrosyid Muchson Arrosyid Muhammad Thesa Ghozali Mustofa, Hana Mustofa, Helmi Nisa, Lia Fakila Nofia Putri Lestari Nurul Hidayati Nurul Hidayati Ocha Ardela Fitria Kresnaya Purwanto Putri Susanti Rahmi Nurhaini, Rahmi Ratna Asmah Susidarti Refida Ramadhani Nur Cholifa Rizky, Alfira Rohmanti, Gandis S Sutaryono Selvi Candra Dewi Septiyanna, Rosemaladewi Sutaryono Sutaryono Sutaryono, S Syahputri, Rezyana Budi Wahyu Anasari Windarsih, Anjar Yenni Kusuma Wardhan Yenni Kusuma Wardhani