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All Journal Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Cancer Berita Kedokteran Masyarakat RESLAJ: Religion Education Social Laa Roiba Journal
Eka R Gunardi
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Religion Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Blood Pressure Elevation Timing Following Hysterectomy Kartiwa Hadi Nuryanto; Kanadi Sumapraja; Marcel Elian Suwito; Eka Rusdianto Gunardi; Seno Adjie; Tofan Widya Utami
Indonesian Journal of Cancer Vol 16, No 3 (2022): September
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v16i3.901

Abstract

Background: Hysterectomy is the most common non-obstetric surgery in adult, reproductive-age women. Hysterectomy with or without ovarian conservation is known to increase the risk of cardiovascular disease. However, only a few studies regarding its immediate and short-term effects on hypertension are available. This study aimed to determine changes in blood pressure after a hysterectomy procedure.Methods: This study is a prospective cohort study of patients who underwent a total hysterectomy procedure with or without ovarian conservation at Cipto Mangunkusumo Hospital, Indonesia, from July 2018 to July 2020. Samples were grouped into patients with total hysterectomy only or hysterectomy with ovarian conservation (HT/HTSOU) and bilateral salpingo-oophorectomy hysterectomy (HTSOB). Statistical analysis was done using paired t-test and Wilcoxon test. Results: There were 80 patients included in this study (40 for each group). A significant increase in all blood pressure components occurred at 12 months after the HT/HTSOU and HTSOB procedures (p < 0.05). After six months of the HTSOB procedure, the increase in blood pressure components only occurred in systolic blood pressure and mean arterial pressure (MAP) (p < 0.05).Conclusions: There was a significant increase in all blood pressure components in the HT/HTSOU and HTSOB group at 12 months following hysterectomy while there was a significant increase in systolic blood pressure and MAP in the HTSOB group at 6 months following hysterectomy.
Unmasking the Culprit: Successful Restoration of Menstrual Function in a Case of Secondary Amenorrhea Due to Tuberculous Endometritis Mimicking Polycystic Ovary Syndrome Riyan Hari Kurniawan; Muhammad Syauqi Mirza; Ilham Utama Surya; Muhammad Dwi Priangga; Cepi Teguh Pramayadi; Herbert Situmorang; Eka Rusdianto Gunardi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1390

Abstract

Background: Secondary amenorrhea presents a significant diagnostic challenge in gynecology. While Polycystic Ovary Syndrome (PCOS) is a common cause, rare etiologies like tuberculous endometritis can be overlooked, especially in patients with features suggestive of PCOS. This phenomenon, known as diagnostic overshadowing, can lead to delayed diagnosis and irreversible reproductive consequences. Case presentation: A 35-year-old nulligravid woman with a diagnosis of Class I Obesity presented with a five-year history of secondary amenorrhea and a desire for fertility. Her clinical and initial ultrasonographic findings were suggestive of PCOS. However, persistent amenorrhea despite hormonal therapy prompted further investigation. Hysteroscopy revealed a fibrotic uterine cavity with micropolyps, and subsequent endometrial biopsy with histopathology, polymerase chain reaction (PCR), and culture confirmed a diagnosis of tuberculous endometritis. The patient was successfully treated with a six-month anti-tuberculosis regimen, cyclical progestin therapy, and a structured lifestyle modification program. Following treatment, she experienced a significant weight loss, resumption of regular menstrual cycles, and marked improvement in endometrial and ovarian ultrasound parameters. Conclusion: This case underscores the critical importance of a comprehensive diagnostic evaluation for secondary amenorrhea, including endometrial sampling, even when a common diagnosis like PCOS is suspected. It highlights the potential for tuberculous endometritis to mimic PCOS and demonstrates the efficacy of a multidisciplinary approach in restoring menstrual and potentially reproductive function. Clinicians in tuberculosis-endemic regions must maintain a high index of suspicion for this insidious pathology to prevent long-term morbidity.
Pregnancy after Succesful Fallopian Tube Recanalization Gunardi, Eka Rusdianto; Trisha Alya Rahmi; Nur Fitri Fadila
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 3 Jully 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i3.2219

Abstract

Objective: To report a pregnancy that ensued following the successful recanalization of a previously sterilized fallopian tube. The novel aspect of this report is its demonstration of a successful intrauterine pregnancy post-recanalization, despite a prior ectopic pregnancy resulting from tubal sterilization. Methods: Case report Case: A 35-year-old woman successfully conceived after the recanalization of a previously sterilized fallopian tube. It is noteworthy that she had previously experienced an ectopic pregnancy due to the tubal sterilization procedure. Conclusion: This case study highlights the potential for successful pregnancy following fallopian tube recanalization, even after an ectopic pregnancy caused by a prior sterilization procedure. This report underscores the complexity of reproductive outcomes in these scenarios. Keywords: fallopian tube recanalization, pregnancy, tube sterilization.
Asymptomatic Uterine Fibroid: The Best Management for Improved QOL in Women by Comparing Laparoscopic and Laparoscopy Hysterectomy (Evidence-Based Medicine) Rahmi, Trisha Alya; Gunardi, Eka Rusdianto; Nabila Budi, Yasmine Syifa; Agustina, Nana; Pramayadi, Cepi Teguh
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 3 November 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i3.746

Abstract

Introduction: Uterine Fibroids (UFs) are benign smooth-muscle neoplasms typically originating from the myometrium. Hysterectomy is the most common non-pregnancy-related surgical procedure performed on women. Laparoscopy Hysterectomy (LH) is currently accepted as a safe and efficient way to manage benign uterine disease with a lower risk of trauma and morbidity. A qualitative approach, which focuses on the Quality of Life of each patient, should help navigate which treatment is more beneficial.Case Illustration: A 56-year-old woman (G0P0) came for a health screening. It was known that about 10 years ago, the patient had a history of uterine myoma. Currently, the patient has no complaints, no abdominal pain, no history of bleeding, history of regular menstruation, and no dysmenorrhea. The patient underwent abdominal laparotomy bilateral salpingo-oophorectomy hysterectomy. Methods: We searched through 3 databases: Pubmed, Cochrane, and ProQuest with the keywords: “Abdominal Hysterectomy” OR “Laparoscopy Hysterectomy” AND “UFS-QOL” with critical review based on the criteria of the Oxford Centre for Evidence-Based Medicine for Qualitative-Studies. Conclusion: Studies show that laparoscopic hysterectomy increased patients’ QOL after the procedure, which revolves around symptom elimination and pain reduction. To ensure holistic and best-practice management, an individual assessment of each patient’s condition according to their symptoms and demographics is needed. Fibroid Uterus Asimptomatik: Penanganan Terbaik untuk Meningkatkan Kualitas Hidup Wanita dengan Membandingkan Histerektomi Laparoskopi dan Laparoskopi (Evidence-Based Medicine)AbstrakPendahuluan: Fibroid Uterus (UFs) merupakan neoplasma jinak otot polos yang biasanya berasal dari miometrium. Histerektomi adalah prosedur bedah non-kehamilan yang paling umum dilakukan pada wanita. Laparoskopi Histerektomi (LH) merupakan salah satu cara yang aman dan efisien untuk menangani penyakit uterus jinak dengan risiko trauma dan morbiditas yang lebih rendah. Pendekatan kualitatif yang berfokus pada kualitas hidup setiap pasien akan membantu menentukan pengobatan mana yang lebih bermanfaat.Ilustrasi Kasus: Seorang wanita berusia 56 tahun (G0P0) datang untuk pemeriksaan kesehatan. Diketahui sekitar 10 tahun yang lalu pasien memiliki riwayat mioma uteri. Saat ini pasien tidak memiliki keluhan apa pun, tidak ada nyeri perut, tidak ada riwayat perdarahan, riwayat menstruasi teratur, dan tidak ada dismenore. Pasien menjalani laparatomi abdomen histerektomi salpingo-ooforektomi bilateral. Metode: Peneliti mencari melalui 3 database: Pubmed, Cochrane, ProQuest dengan kata kunci: “Abdominal Histerektomi” ATAU “Histerektomi Laparoskopi” DAN “UFS-QOL” dengan tinjauan kritis berdasarkan kriteria Oxford Centre for Evidence Based Medicine for Qualitative-Studies. Kesimpulan: Penelitian menunjukkan bahwa histerektomi laparoskopi telah terbukti meningkatkan kualitas hidup pasien setelah prosedur dengan tujuan untuk menghilangkan gejala dan mengurangi rasa sakit. Untuk memastikan penatalaksanaan yang holistik dan praktik terbaik, diperlukan penilaian individual terhadap kondisi setiap pasien sesuai dengan gejala dan demografinya.Kata kunci: Fibroid Uterus, Kuesioner Gejala Fibroid Uterus, Laparoskopi Histerektomi, Abdominal Histerektomi
Tingkat Nyeri dan Kualitas Hidup pada Pasien Endometriosis Setelah Pemasangan Implan Levonorgestrel Ramadhani Sheba Arifin; Dwi Retna Lestari; Agus Sujono; Eka Rusdianto Gunardi
Reslaj: Religion Education Social Laa Roiba Journal Vol. 6 No. 8 (2024): RESLAJ: Religion Education Social Laa Roiba Journal 
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/reslaj.v6i8.4501

Abstract

Endometriosis is characterized by the presence of tissue resembling endometrial glands that grows outside the uterus. This condition triggers a chronic inflammatory reaction which results in pain and adhesions. Pain in endometriosis patients is the most common complaint experienced and has an impact on quality of life. Hormonal therapy to treat pain in endometriosis patients, one of which can use progesterone. The Levonorgestrel implant is a long-term contraceptive method that contains the hormone progesterone with high effectiveness. The aim of the study was to assess the efficacy of levonogestrel implants in improving pain and quality of life in endometriosis patients. This research is descriptive qualitative. A total of 10 subjects who met the inclusion criteria had implants installed and were followed for 6 months after LNG implant insertion. Pain improvement was assessed using VAS scores and quality of life with the EHP-30 questionnaie.
Peranan Kontrasepsi Dahulu, Sekarang dan Masa Depan Eka Rusdianto Gunardi; Denny Khusen; Kevin Winston
Majalah Kedokteran Indonesia Vol 68 No 8 (2018): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.68.8-2018-50

Abstract

Contraceptives play an undeniable important role in woman’s lives. It is widely accepted that the availability of both hormonal and non-hormonal modern contraceptives have improved 0 women’s lives worldwide by allowing women to control their own fertility. Indirectly, contraceptives have been shown to reduce maternal mortality, unwanted pregnancy, and overpopulation. However, the contraceptives available today may not be suitable for all users. Furthermore, there is still need to expand available current contraceptives choices especially long-term contraceptives in order to improve acceptability. As a result, several novel products such as implants, contraceptive vaginal rings, and transdermal patches have recently been introduced in family planning programs. Additional issue of contraceptive needed to be addressed is the adverse effects of hormonal contraceptives. Therefore, new combinations with an improved metabolic profile is currently being researched. Generally, the introduction of new methods with additional health benefits and less side effects would help women with their unmet needs to obtain access to a wider range of contraceptives.
Diagnosis and Management of Complex Genital Warts: Case Report Ilham Utama Surya; Eka Rusdianto Gunardi; Trisha Alya Rahmi; Dhifa Dwi Putra; Syauqi Mirza
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 3 November 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i3.888

Abstract

Introduction: This case reports a pregnancy complicated by condyloma acuminata with co-infection of HIV and tuberculosis (TB). Such a combination is rarely documented and presents significant clinical and therapeutic challenges. This case aims to demonstrate the effectiveness of a simple surgical approach in managing extensive condyloma acuminata during high-risk pregnancy.Case Presentation: A 24-year-old pregnant woman was diagnosed with condyloma acuminata along with confirmed HIV and TB co-infection. Electrocauterization was performed successfully, leading to complete lesion removal and significant improvement in wound healing, with no early recurrence observed. The pregnancy was planned to be delivered by cesarean section.Conclusion: This case demonstrates that, even with multiple comorbidities and a high-risk pregnancy, simple surgical treatments like electrocauterization can be both safe and effective. Early multidisciplinary intervention is crucial for achieving the best maternal outcomes.Diagnosis dan Penatalaksanaan Kondiloma Genital dengan Komplikasi: Laporan KasusAbstrakPendahuluan: Laporan kasus ini membahas kehamilan yang disertai komplikasi berupa kondiloma akuminata dengan ko-infeksi HIV dan tuberkulosis (TB). Kombinasi tersebut jarang didokumentasikan dan menimbulkan tantangan klinis serta terapeutik yang signifikan. Kasus ini bertujuan untuk menunjukkan efektivitas pendekatan bedah sederhana dalam menangani kondiloma akuminata ekstensif pada kehamilan risiko tinggi.Presentasi Kasus: Seorang wanita hamil berusia 24 tahun didiagnosis menderita kondiloma akuminata dengan ko-infeksi HIV dan TB terkonfirmasi. Tindakan elektrokauter berhasil dilakukan dengan hasil berupa pengangkatan lesi secara menyeluruh dan perbaikan yang nyata pada penyembuhan luka, tanpa adanya kekambuhan dini yang teramati. Kehamilan direncanakan untuk dilahirkan dengan operasi sesar.Kesimpulan: Kasus ini menegaskan bahwa dalam konteks komorbiditas multipel dan kehamilan risiko tinggi, penatalaksanaan bedah sederhana seperti elektrokauter dapat aman dan efektif. Intervensi multidisiplin sejak dini sangat penting untuk mencapai luaran maternal yang optimal.Kata kunci: HIV: Kehamilan; kondiloma akuminata; tuberkulosis
Accuracy of Tubal Patency Assessment during Office Hysteroscopy in Comparison to Hysterosalpingography Nessyah Fatahan; Herbert Situmorang; Eka Rusdianto Gunardi; Muhammad Dwi Priangga
Indonesian Journal of Obstetrics and Gynecology Volume 14. No. 2 April 2026
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v14i2.2428

Abstract

AbstractObjective: To evaluate the accuracy of office hysteroscopy in assessing tubal patency compared with hysterosalpingography. Methods: This cross-sectional study was conducted from January 2021 to May 2023 and involved 26 subjects who underwent office hysteroscopy as part of a subfertility work-up. Tubal patency was assessed using the bubble test (Parryscope test) and by measuring changes in the amount of fluid in the pouch of Douglas after the procedure. All subjects subsequently underwent hysterosalpingography as the standard method. Due to technical limitations, diagnostic laparoscopy the gold standardwas not performed. Agreement between office hysteroscopy and hysterosalpingography was evaluated using concordance rates and kappa values, along with sensitivity, specificity, positive predictive value, and negative predictive value. Pain scores during the procedure and post-procedural symptoms were also analyzed. Results: The concordance between the two modalities in assessing tubal patency was 67% (moderate agreement), with a kappa value of 0.28 (fair agreement). Office hysteroscopy resulted in lower pain scores and a reduced incidence of post procedural lower back pain and abdominal bloating. Conclusion: Office hysteroscopy demonstrates fair accuracy in assessing tubal patency compared with hysterosalpingography, with the advantages of minimal pain and no serious side effects. Keywords: HSG, office hysteroscopy, tubal patency.
Drospirenone–Ethinyl Estradiol and Cyproterone Acetate in Moderate Severe Acne with Hyperandrogenism: A Randomized Double-Blind Trial Eka Rusdianto Gunardi; Irma Bernadette; Riyan Hari Kurniawan; Astri Noviani
Indonesian Journal of Obstetrics and Gynecology Volume 14. No. 1 January 2026
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v14i1.3181

Abstract

ABSTRACT Background: Acne vulgaris is a health problem experienced by 85% of people in Indonesia. The highest prevalence is in women, who attempt to treat acne vulgaris. Unsuccessful acne vulgaris therapy is associated with hormonal influences, the stimulation of the sebaceous glands by androgen hormones. Hyperandrogenism is experienced by 10% of women in Indonesia. The main therapy for hyperandrogens is ciproterone acetate. Drospirenone combined with ethinyl estradiol, apart from sparing pregnancy, is also thought to be effective in treating clinical symptoms of hyperandrogenism. Currently, there is no study on drospirenone for acne and hyperandrogen therapy in Indonesia. Objective: Determine the efficacy of treatment combination 3-mg drospirenone and 20-microgram ethinyl estradiol as management of choice for moderate-severe acne vulgaris and symptoms of hyperandrogenism (hirsutism, secondary amenorrhea, and oligomenorrhea) for 3 cycles. Method: A randomized clinical trial with a double-blind study was done. Consecutive sampling is based on a random allocation table. A total of 42 subjects were diagnosed with moderate-severe acne vulgaris with hirsutism, secondary amenorrhea and/or oligomenorrhea at RSCM, divided into 2 groups, 21 subjects using drospirenone 3 mg combined with 0.030 mg ethinyl estradiol (DRSP/EE) and 21 subjects using 2 mg ciproterone acetate and 0.035 mg ethinyl estradiol (CRPN/EE), followed with examination of free testosterone check in laboratory. There was 1 subject who dropped out (Cyproterone group). The duration of therapy was 3 months then evaluation of acne lesions, Ferriman Gallwey score (FG score), and menstrual period. Results: Characteristics of study subjects with the majority of subjects aged 25-35 years, 51,3%. The education level of most subjects about 57,1%, was a bachelor's degree. Testosterone levels at the start of the study were 1,41±0,64 for the DRSP/EE group and 1,32±0,48 for the CRPN/EE group. For the degree of acne, 85.7% of subjects using DRPS/EE and 85% of subjects using CPRN/EE had reduced acne lesions with a P value of 0.645. For hirsutism by calculating the FG score, 61.9% of the subjects using DRSP/EE and 50% of the subjects consumed CPRN/EE had a decreased FG score with a value of P value 0.443, and their menstrual period became regular for 85.7% of the subjects using DRSP/EE and 90% of the subjects using CPRN/EE with P value 0.645. Conclusion: Drospirenone and ethinyl estradiol are as effective as cyproterone acetate combined with ethyl estradiol as treatment of moderate to severe acne vulgaris, hirsutism, secondary amenorrhea, and oligomenorrhea. Keywords: acne vulgaris, cyproterone acetate, drospirenone, hirsutism, secondary amenorrhea
Management of Postpartum Hemorrhage: A Comprehensive Review of Current Evidence and International Guideline Recommendations Eka Rusdianto Gunardi
Indonesian Journal of Obstetrics and Gynecology Volume 14. No. 2 April 2026
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v14i2.3325

Abstract

N/A
Co-Authors Addina, Putri Adi Utarini Adila RA Malik Affan Solihin Agus Sujono Aldri Frinaldi Alexander Mukti Andon Hestiantoro Andrijono Anita Tobing Ardianto, Fachreza Arnold Soetarso Arresta Suastika Arresta Vitasatria Suastika Astri Noviani Ballo, Frista Betaria Putri Biran Affandi Biran Affandi Cepi T. Pramayadi Cepi Teguh Pramayadi Christina Marian Darrell Fernando Denny Khusen Denny Khusen Dhifa Dwi Putra Duta A Tritama Dwi Retna Lestari Fachreza Ardianto Fadli Fadli Fadli Fadli Farid, Retno B Febby Oktavianti Frista Ballo Gatot Purwoto Hadiyono, Suryo Hanevi Djasri Hariyono Winarto Herbert Situmorang Herbert Situmorang Heriyadi Manan Heru Prasetyo Hoesni, R Hasan M Ichsan, TM Ilham Utama Surya Ilham Utama Surya Irma Bernadette Jimmy T. Sitorus JM Seno Adjie Johny Judio Judio, Johny Kanadi Sumapradja Kartika Mayasari Kartiwa Hadi Nuryanto Kevin Winston Leonanta M. Ginting Lestari, Renny Luky Satria Malik, Adila RA Manan, Heriyadi Manan, Heriyadi Marcel Elian Suwito Mardiah Taher Marian, Christina Meria,, Riry Muhammad D. Priangga Muhammad Dwi Priangga Muhammad Dwi Priangga Muhammad Syauqi Mirza Mukti, Alexander Nabila Budi, Yasmine Syifa Nana Agustina Nessyah Fatahan Noor Pramana Nur Fitri Fadila Oktavianti, Febby Pramana, Noor Pramayadi, Cepi Teguh Putri Addina R Hasan M Hoesni Raden Muharam Natadisastra Rahmi, Trisha Alya Ramadhani Sheba Arifin Renny Lestari Retno B Farid Ribkhi A. Putri Ridwan, Rusdi S Riry Meria, Riyan H. Kurniawan Riyan Hari Kurniawan Rizani Amran Rusdi S Ridwan Satria, Luky Soetarso, Arnold Suryo Hadiyono Syauqi Mirza Taher, Mardiah Tandjung, Thamrin Thamrin Tandjung TM Ichsan Tofan Widya Utami Trisha Alya Rahmi Trisha Alya Rahmi Tritama, Duta A Wachyu Hadisaputra Wachyu Hadisaputra Widohariadi Widohariadi Widohariadi Widohariadi Winston, Kevin Yudianto B Saroyo