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All Journal Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Cancer Berita Kedokteran Masyarakat RESLAJ: Religion Education Social Laa Roiba Journal
Eka R Gunardi
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Religion Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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The Effectiveness of Misoprostol Single Dose Oral for Evacuation of Incomplete Abortion Eka Rusdianto Gunardi; Affan Solihin
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), Vol. 16 No. 02 Desember 20
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v16i2.4591

Abstract

This study is aimed to find out the effectiveness of oral 600 mcg single dose misoprostol for the evacuation of conception remnant in cases of incomplete abortion. This research is done by quasi experimental method with one group pretest – posttest design. The population of the study is all women who were diagnosed with incomplete abortion in less than 12 weeks of gestation in Cipto Mangunkusumo National general Hospital and affiliations hospital from June 2018 to June 2019. Women who met the study criteria, was treated with oral misoprostol 600 mcg single dose and then undergo conception evacuation evaluation and side effects evaluation. Effectiveness evaluation was seen after 7 days of single dose 600 mcg of misoprostol by measuring <15 mm endometrial thickness on transvaginal ultrasound. The effectiveness of using single dose oral misoprostol 600 mcg in the study participants was 93.55%, which were 29 out of a total of 31 participants. The side effects experienced after being given misoprostol were bleeding with less than the same amount as menstruation (71.0% and 9.0%), diarrhea (6.5%), and shivering (67.7%), and not found side effects of vomiting. Based on data analysis using paired T test before and 24 hours after administration of misoprostol, there was a significant difference between endometrial thickness (p value <0.001). Misoprostol 600 mcg per oral dose is effective for the evacuation of retained conception tissue of incomplete abortion at less than 12 weeks gestation, so that it can be an alternative non-operative method of evacuating retained conception tissue in incomplete abortion cases other than the operative method. Side effects found were bleeding, diarrhea, and chills. Side effects of vomiting were not found in this study.
Co-Authors Addina, Putri Adi Utarini Adila RA Malik Affan Solihin Agus Sujono Aldri Frinaldi Alexander Mukti Andon Hestiantoro Andrijono Anita Tobing Ardianto, Fachreza Arnold Soetarso Arresta Suastika Arresta Vitasatria Suastika Astri Noviani Ballo, Frista Betaria Putri Biran Affandi Biran Affandi Cepi T. Pramayadi Cepi Teguh Pramayadi Christina Marian Darrell Fernando Denny Khusen Denny Khusen Dhifa Dwi Putra Duta A Tritama Dwi Retna Lestari Fachreza Ardianto Fadli Fadli Fadli Fadli Farid, Retno B Febby Oktavianti Frista Ballo Gatot Purwoto Hadiyono, Suryo Hanevi Djasri Hariyono Winarto Herbert Situmorang Herbert Situmorang Heriyadi Manan Heru Prasetyo Hoesni, R Hasan M Ichsan, TM Ilham Utama Surya Irma Bernadette Jimmy T. Sitorus JM Seno Adjie Johny Judio Judio, Johny Kanadi Sumapradja Kartika Mayasari Kartiwa Hadi Nuryanto Kevin Winston Leonanta M. Ginting Lestari, Renny Luky Satria Malik, Adila RA Manan, Heriyadi Manan, Heriyadi Marcel Elian Suwito Mardiah Taher Marian, Christina Meria,, Riry Muhammad D. Priangga Muhammad Dwi Priangga Muhammad Dwi Priangga Muhammad Syauqi Mirza Mukti, Alexander Nabila Budi, Yasmine Syifa Nana Agustina Nessyah Fatahan Noor Pramana Nur Fitri Fadila Oktavianti, Febby Pramana, Noor Pramayadi, Cepi Teguh Putri Addina R Hasan M Hoesni Raden Muharam Natadisastra Rahmi, Trisha Alya Ramadhani Sheba Arifin Renny Lestari Retno B Farid Ribkhi A. Putri Ridwan, Rusdi S Riry Meria, Riyan H. Kurniawan Riyan Hari Kurniawan Rizani Amran Rusdi S Ridwan Satria, Luky Soetarso, Arnold Suryo Hadiyono Syauqi Mirza Taher, Mardiah Tandjung, Thamrin Thamrin Tandjung TM Ichsan Tofan W Utami Trisha Alya Rahmi Trisha Alya Rahmi Tritama, Duta A Wachyu Hadisaputra Wachyu Hadisaputra Widohariadi Widohariadi Widohariadi Widohariadi Winston, Kevin Yudianto B Saroyo