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All Journal MEDIA MEDIKA INDONESIANA Jurnal Berkala Epidemiologi MNJ (Malang Neurology Journal) Majalah Obstetri dan Ginekologi Sari Pediatri Jurnal Ilmiah Kedokteran Wijaya Kusuma Universa Medicina Paediatrica Indonesiana Health Notions Syntax Literate: Jurnal Ilmiah Indonesia PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Majalah Kedokteran Neurosains JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Neurologico Spinale Medico Chirurgico Jurnal Abdi Insani Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Cermin Dunia Kedokteran AKSONA MEDICINUS Neurona Ophthalmologica Indonesiana Jurnal Widya Medika
Prastiya Indra Gunawan
Departemen Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Unversitas Airlangga Surabaya
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Outcome of infants with hydrocephalus findings on Intra-Uterine Ultrasound (USG) examination at Dr. Soetomo Hospital, Surabaya, Indonesia, in 2015-2017 Lourin Nova; Mohammad Aldika Akbar; Agus Sulistyono; Wihasto Suryaningtyas; Prastiya Indra Gunawan
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.133-139

Abstract

Objectives: to report the outcome of cases with hydrocephalus findings on intra-uterine ultrasound (USG) examinations which happened between January 2015 - December 2017 at Dr. Soetomo Hospital.Case Report: During the period of January 2015 - December 2017, 20 pregnant women were found who performed an ante natal examination and obtained the fetus with hydrocephalus on intra uterine ultrasound examination. At the time of delivery, out of a total of 20 cases, all babies were born alive, but only 12 babies performed shunting operations with VP Shunt. But at the time of follow up the condition of the baby when the search of this case, found only 7 cases with living conditions. This is probably due to non-routine post-action control to ensure shunt conditions and complications that can result from shunt or other conditions. As seen from the growth and development of 7 surviving children, all cases with normal growth conditions were established based on WHO growth curve and developmental obstacles in all cases with evaluation using DDST II.Conclusion: Ultrasound examination is useful for determining the fetal prognosis, but for fetoscopic examination and intra uterine operative action remains controversial. Similarly, to determine the exact termination time and delivery mode. Pre-natal counseling and examination is required in mothers with a history of fetal hydrocephalus in previous pregnancies. With routine control is expected better outcomes in fetal hydrocephalus.
Outcome of infants with hydrocephalus findings on Intra-Uterine Ultrasound (USG) examination at Dr. Soetomo Hospital, Surabaya, Indonesia, in 2015-2017 Lourin Nova; Mohammad Aldika Akbar; Agus Sulistyono; Wihasto Suryaningtyas; Prastiya Indra Gunawan
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.133-139

Abstract

Objectives: to report the outcome of cases with hydrocephalus findings on intra-uterine ultrasound (USG) examinations which happened between January 2015 - December 2017 at Dr. Soetomo Hospital.Case Report: During the period of January 2015 - December 2017, 20 pregnant women were found who performed an ante natal examination and obtained the fetus with hydrocephalus on intra uterine ultrasound examination. At the time of delivery, out of a total of 20 cases, all babies were born alive, but only 12 babies performed shunting operations with VP Shunt. But at the time of follow up the condition of the baby when the search of this case, found only 7 cases with living conditions. This is probably due to non-routine post-action control to ensure shunt conditions and complications that can result from shunt or other conditions. As seen from the growth and development of 7 surviving children, all cases with normal growth conditions were established based on WHO growth curve and developmental obstacles in all cases with evaluation using DDST II.Conclusion: Ultrasound examination is useful for determining the fetal prognosis, but for fetoscopic examination and intra uterine operative action remains controversial. Similarly, to determine the exact termination time and delivery mode. Pre-natal counseling and examination is required in mothers with a history of fetal hydrocephalus in previous pregnancies. With routine control is expected better outcomes in fetal hydrocephalus.
Efikasi dan Toleransi Monoterapi Topiramate pada Epilepsi Prastiya Indra Gunawan
Sari Pediatri Vol 15, No 3 (2013)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp15.3.2013.195-200

Abstract

Latar belakang. Epilepsi merupakan masalah besar dalam bidang pediatri, masih terdapat 10%-15% pasien yang resisten terhadap pengobatan. Topiramate sebagai obat antiepilepsi baru mempunyai spektrum luas untuk anti kejang. Penelitian sebagai add on therapy dan monoterapi dewasa membuktikan topiramate mempunyai potensi yang baik. Data efektifitas dan efek samping topiramate sebagai monoterapi pada anak-anak masih sulit didapatkan.Tujuan. Menilai efikasi dan toleransi topiramate untuk monoterapi pasien pediatri dengan epilepsi.Metode. Penelitian pra-eksperimental dilakukan di Poliklinik Neurologi Anak RSUD Dr Soetomo, Surabaya dengan 15 subjek. Subjek yang sesuai kriteria diberikan terapi topiramate dan dilakukan pengukuran frekuensi kejang, serta efek samping pada minggu 1, 4, 8, 12, 16, 20, dan 24. Gambaran EEG dan pemeriksaan laboratorium dilakukan sebelum dan sesudah terapi selama 6 bulan. Analisis statistik menggunakan T-test for related samples dan McNemar.Hasil. Frekuensi kejang awal 2,7 (1,16) menjadi 0,13 (0,51) dengan 93,7% pasien bebas kejang pada minggu ke-20 (p=0,000). Gambaran EEG awal menunjukkan aktifitas epileptiform menjadi normal pada 20% subyek. Tigapuluh persen sampel mengalami penurunan nafsu makan pada saat awal terapi, dan 7% mengalami rasa kantuk.Kesimpulan. Terdapat reduksi frekuensi kejang dan tidak terdapat perubahan EEG pasca pemberian pemberian topiramate. Efek samping yang ditemukan adalah mengantuk dan penurunan nafsu makan.
Profil Klinis dan Faktor Risiko Mortalitas pada Anak dengan Hidrosefalus di RSUD dr. Soetomo Surabaya Nabila Fitri Ariyati; Prastiya Indra Gunawan; Florentina Sustini
Sari Pediatri Vol 22, No 6 (2021)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp22.6.2021.364-70

Abstract

Latar belakang. Hidrosefalus merupakan kelainan sistem saraf pusat yang paling umum terjadi baik pada bayi, anak, maupun remaja dan dapat menyebabkan konsekuensi serius berupa mortalitas. Informasi yang menyediakan faktor risiko mortalitas pada anak dengan hidrosefalus masih sangat terbatas.Tujuan. Mengevaluasi dan mengidentifikasi faktor risiko yang berhubungan dengan terjadinya mortalitas pada anak dengan hidrosefalus.Metode. Penelitian analitik observasional pada 89 pasien anak yang menderita hidrosefalus dengan menggunakan data rekam medis pasien anak yang dirawat di bagian instalasi rawat inap RSUD dr. Soetomo periode Januari 2014 hingga September 2016. Analisis menggunakan chi-square dan regresi logistik.Hasil. Didapatkan 89 subjek yang memenuhi kriteria inklusi. Mortalitas pasien anak dengan hidrosefalus adalah 17,97%. Analisis bivariat menunjukkan adanya hasil signifikan pada infeksi meningoensefalitis dengan OR 8,12 (95% CI 2,38-27,6) p=0,001. Sepsis memiliki OR 6,18 (95% CI 1,53-24,9) p=0,01. Kelainan struktur SSP berupa brain edema memiliki OR 4,27 (95% CI 1,25-14,6) p=0,02. Gagal nafas memiliki OR 56,0 (95% CI 6,16-508,9) p=0,001. Hasil analisis multivariat menunjukkan gagal nafas dan brain edema memiliki nilai OR (95% CI) berturut-turut 192,8 (9,92-3745,8) dan 10,07(1,23-82,5) dengan nilai p<0,05.Kesimpulan. Gagal nafas dan brain edema merupakan faktor risiko mortalitas pada anak dengan hidrosefalus.
Profil Epilepsi Anak dan Keberhasilan Pengobatannya di RSUD Dr. Soetomo Tahun 2013 Pravita Tri Andrianti; Prastiya Indra Gunawan; Faroek Hoesin
Sari Pediatri Vol 18, No 1 (2016)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp18.1.2016.34-39

Abstract

Latar belakang. Epilepsi adalah satu dari tiga kelainan neurologis tersering yang ditemui di praktek pediatri. Insiden epilepsi di negara berkembang dua kali lebih banyak daripada negara industri.Tujuan. Mengetahui profil epilepsi pada anak dan keberhasilan pengobatannya di RSUD Dr. Soetomo, Surabaya.Metode. Studi deskriptif retrospektif menggunakan rekam medis,variabel meliputi jumlah kasus baru, usia, jenis kelamin, riwayat keluarga, EEG, CT-scan, MRI dan keberhasilan terapi selama 2013 di RSUD Dr. Soetomo Surabaya.Hasil. Terdapat 103 kasus baru epilepsi anak terbanyak usia 1-5 tahun (45,63%), laki-laki (71,84%), tanpa pengobatan sebelumnya (32,04%), riwayat keluarga kejang/epilepsi (93,20%), kelainan perinatal (83,50%), maupun gangguan tumbuh kembang (63,11%). Hasil EEG 72,84% abnormal, 61,53% CT-scan kepala normal dan 57,14% MRI normal. Tipe bangkitan 55,34% general. Obat yang diberikan adalah asam valproat (89,32%) dan 75,73% kejang dapat terkontrol.Kesimpulan. Terdapat 103 kasus baru epilepsi anak, terbanyak usia 1-5 tahun dan laki-laki. Hasil pemeriksaan EEG umumnya abnormal di lobus temporal, tetapi lebih dari separuh kasus memperlihatkan CT-scan kepala dan MRI normal. Asam valproat terbanyak digunakan mengontrol kejang.
Profil Klinis dan Faktor Risiko Hidrosefalus Komunikans dan Non Komunikans pada Anak di RSUD dr. Soetomo Denisa Dwi Rahmayani; Prastiya Indra Gunawan; Budi Utomo
Sari Pediatri Vol 19, No 1 (2017)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp19.1.2017.25-31

Abstract

Latar belakang. Hidrosefalus merupakan salah satu kelainan kongenital tersering pada anak yang dapat menyebabkan penurunan kualitas hidup anak. Penyebab hidrosefalus masih belum banyak diketahui dan faktor risikonya belum banyak dipelajari. Tujuan. Mengevaluasi dan mengidentifikasi faktor risiko yang berhubungan dengan terjadinya hidrosefalus komunikans dan non komunikans pada anak. Metode. Penelitian analitik observasional pada 80 pasien anak yang menderita hidrosefalus dengan menggunakan data sekunder di pusat rekam medis RSUD dr. Soetomo. Analisis menggunakan chi-square dan regresi logistik. Hasil. Prevalensi hidrosefalus komunikans dan non komunikans adalah 41,25% dan 58,75%. Hasil analisis menunjukkan meningoensefalitis memiliki hubungan dengan hidrosefalus komunikans (p=0,023). Data statistik menunjukkan bahwa manifestasi klinis terbanyak pada hidrosefalus adalah edema otak. Kesimpulan. Meningoensefalitis merupakan faktor risiko hidrosefalus komunikans.
Assessment Quality of Life in Children with Cerebral Palsy, Ages 2–18 Years Alfira Nailatul Izzah; Irwanto Irwanto; Andriati Andriati; Prastiya Indra Gunawan
Jurnal Berkala Epidemiologi Vol. 9 No. 2 (2021): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V9I22021.166-174

Abstract

Background: Cerebral palsy is non-progressive disorder that can cause limited movement and lead to postural deformity in children, which can affects all the psychosocial aspects and, thus, impacts children’s’ quality of life as well. Assessment of quality of life is important to evaluate suitable intervention measures for children with cerebral palsy. Purpose: This study aims to investigate the domains and determine the quality of life in children with cerebral palsy between ages 2 and 18. Methods: This was a descriptive study that employed a cross-sectional design approach. Primary data was obtained through a questionnaire. This study used the pediatric quality of life inventory (PedsQL)TM 3.0 cerebral palsy module. The study was conducted from November 2019 to February 2020. The data was collected at the Department of Medical Rehabilitation at the Dr. Soetomo Hospital, Peduli CP Foundation, and the Happy CP Community. This study involved 52 subjects, aged 2–18 years. Results: Almost all of the subjects (76.90%) had an impaired or poor quality of life. From the seven existing domains, only one domain received a good score: the domain of movement and balance. Conclusion: Based on the PedsQLTM 3.0 cerebral palsy module, parents reported that the quality of life in children (ages 2–18 years) having cerebral palsy was still low. Only the movement and balance domain got a good score.
PROFILE OF NEURAL TUBE DEFECT IN RSUD Dr. SOETOMO, 2013-2018 Mohammad Nata Ardiansyah; Muhammad Arifin Parenrengi; Prastiya Indra Gunawan; Wihasto Suryaningtyas
Jurnal Berkala Epidemiologi Vol. 10 No. 2 (2022): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V10I22022.199-209

Abstract

Background: Congenital abnormalities are structural growth abnormalities that have arisen since the intrauterine life caused by many factors, including genetics, pregnancy nutrition, infection, and social status. Purpose: This study aims to observe the clinical profile of Neural Tube Defect (NTD) patients in Dr. Soetomo Hospital from 2013 to 2018. Methods: This research was a descriptive study using secondary data from medical records from September 2013 to March 2018 to determine the profile of NTDs. The inclusion criteria for this study were patients aged 1-14 years diagnosed with NTD. Variables observed included gender, age, primary diagnosis, natal history, nutritional status, history of past therapy, referral status, comorbidities, and outputs. Data analysis was conducted in a descriptive method and presented in tables and diagrams. Results: This study found that out of 232 samples, 122 were female and 110 were male. Spina bifida unspecified was the most common diagnosis in 80 patients (32.78%), then encephalocele unspecified, 50 (20.49%), encephalocele anterior, 31 (12.44%), Myelomeningocele (MMC), 25 (10.24%), encephalocele unspecified, 23 (9.42%), and lipomyelocele, 20 (8.19%). There was 244 diagnosis found with 12 dual diagnoses. Works done depend on the clinical and nutritional condition of the patient. Patients with NTD tend to need more nutrition. Most NTD patients present with comorbidities, and the most common one is hydrocephalus. Many NTD patients had unknown treatment output. Most patients were still in outpatient care for further supervision. Conclusion: NTD incidence rate in RSUD Dr. Soetomo 2013-2018 is still relatively high.
PROFILE OF NEURAL TUBE DEFECT IN RSUD Dr. SOETOMO, 2013-2018 Mohammad Nata Ardiansyah; Muhammad Arifin Parenrengi; Prastiya Indra Gunawan; Wihasto Suryaningtyas
Jurnal Berkala Epidemiologi Vol. 10 No. 2 (2022): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V10I22022.199-209

Abstract

Background: Congenital abnormalities are structural growth abnormalities that have arisen since the intrauterine life caused by many factors, including genetics, pregnancy nutrition, infection, and social status. Purpose: This study aims to observe the clinical profile of Neural Tube Defect (NTD) patients in Dr. Soetomo Hospital from 2013 to 2018. Methods: This research was a descriptive study using secondary data from medical records from September 2013 to March 2018 to determine the profile of NTDs. The inclusion criteria for this study were patients aged 1-14 years diagnosed with NTD. Variables observed included gender, age, primary diagnosis, natal history, nutritional status, history of past therapy, referral status, comorbidities, and outputs. Data analysis was conducted in a descriptive method and presented in tables and diagrams. Results: This study found that out of 232 samples, 122 were female and 110 were male. Spina bifida unspecified was the most common diagnosis in 80 patients (32.78%), then encephalocele unspecified, 50 (20.49%), encephalocele anterior, 31 (12.44%), Myelomeningocele (MMC), 25 (10.24%), encephalocele unspecified, 23 (9.42%), and lipomyelocele, 20 (8.19%). There was 244 diagnosis found with 12 dual diagnoses. Works done depend on the clinical and nutritional condition of the patient. Patients with NTD tend to need more nutrition. Most NTD patients present with comorbidities, and the most common one is hydrocephalus. Many NTD patients had unknown treatment output. Most patients were still in outpatient care for further supervision. Conclusion: NTD incidence rate in RSUD Dr. Soetomo 2013-2018 is still relatively high.
Age decreases quality of life in adolescents with intractable epilepsy Prastiya Indra Gunawan; Theresa Laura Limanto; Darto Suharso
Universa Medicina Vol. 34 No. 2 (2015)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.104-111

Abstract

BackgroundIntractable epilepsy considerably affects both the private and social life of the patient. The objective of this study was to determine the quality of life of intractable epileptic adolescents and its correlated factors. Methods A cross sectional study was conducted in the Pediatric Neurology outpatient clinic of Dr. Soetomo Hospital. All intractable epileptic adolescents aged between 10 to 16 years were asked to complete a questionnaire on quality of life in epilepsy for adolescents (QOLIE-AD-48). A multiple linear regression was used to analyze the data through SPSS v17.0.ResultsThirty one patients with mean age of 12.41 ± 1.40 years were enrolled in the study. The mean duration of diagnosed intractable epilepsy was 6.12 ± 4.30 years. Mean score for impact of epilepsy was 57.11 ± 24.50, for memory and concentration 53.54 ± 26.66, physical functioning 65.56 ± 23.67, social stigma 52.23 ± 17.48, social support 52.64 ± 22.69, behavior at school 57.51 ± 26.50, attitude 53.40 ± 16.70 and health perception 61.51 ± 11.30. Multiple linear regression results showed that quality of life (QOL) was not significantly correlated with duration of epilepsy, sex and nutritional status (p>0.05), but increasing age was significantly decreases quality of life (p<0.05). ConclusionsIntractable epileptic adolescents have higher scores for physical functioning and health perception, but lower scores for social stigmatization. Social support has extremely low scores. Increasing age decreases quality of life in adolescents with intractable epilepsy.
Co-Authors Abdurachman Abdurachman Adinda Chairunnisa Aditiawarman Aditiawarman, Aditiawarman Agus Sulistyono Alfira Nailatul Izzah Aminuddin Harahap Andriati Andriati Arina Setyaningtyas Arinda Putri Auna Vanadia Avida Marisa Ilmi Basyarahil, Rayhan Muhammad Budi Utomo Darto Saharso Darto Suharso Darto Suharso, Darto Denisa Dwi Rahmayani Dwiyanti Puspitasari, Dwiyanti DYAH FAUZIAH, DYAH Faroek Hoesin Felice, Calista Florentina Sustini Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Heru Setiawan Indri Wahyuni Irwanto, Irwanto Islamiyah, Wardah Rahmatul Kanti Ismayani Lourin Nova Martono Tri Utomo Mohammad Aldika Akbar Mohammad Nata Ardiansyah Mohammad Sjaifullah Noer Muhammad Rizki Darmawan M Nabila Annisa Harum Nabila Fitri Ariyati Ni Wayan Tirthaningsih Ninik Asmaningsih Soemyarso Noviandi, Riza Nuramalia, Lady Sherly Parenrengi, Muhammad Arifin Prastyani, Reni Pravita Tri Andrianti Ratih Dwi Andini Risky Vitria Prasetyo Riza Noviandi Riza Noviandi Riza Noviandi Romdhoni, Achmad Chusnu Rozalina Loebis, Rozalina Samosir, Sunny Mariana Sri Andreani Utomo, Sri Andreani Sunny Mariana Samosir Sunny Mariana Samosir Theresa Laura Limanto Viskasari P. Kalanjati wihasto suryaningtyas Wirawan, Putu Tanisya Putri Zhafira, Dinda