Dewi Anggraini
1) Arifin Achmad General Hospital, Riau Province, Pekanbaru, Indonesia 2) Eka Hospital Pekanbaru, Pekanbaru, Indonesia 3) Department Of Microbiology, Faculty Of Medicine, Universitas Riau, Pekanbaru, Indonesia

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Journal : Jurnal Ilmu Kedokteran (Journal of Medical Science)

Cotrimoxasole-Resistant Stenotropomonas maltophilia Infection : Case Report Dani Rosdiana; Dewi Anggraini
Jurnal Ilmu Kedokteran Vol 12, No 1 (2018): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.709 KB) | DOI: 10.26891/JIK.v12i1.2018.57-61

Abstract

Stenotrophomonas maltophilia is an important multidrug-resistant nosocomial pathogen associated with high mortality. This infection did not elucide clearly in Riau. We reported two Cotrimoxaxole Resistant Stenotrophomonas maltophilia in patient of Arifin Achmad Hospital which refered from peripheral hospital in another region. They had similar clinical appereance such as long stay hospitalization, bad clinical appearance and had a history of meropenem exposure before. We performed urin culture to make appropriate diagnostic and treatment also. Stenotrophomonas maltophilia bacteria was found in urine isolate. The sensitivity test showed that this bacteria had Cotrimoxasole resistant that standard antibiotic of this bacteria. The management of these cases become complicated due to decrease of renal function in one patient. We had to make dose adjustment of parenteral levofloxacin, giving good nutrition,  counted fluid balance and repaired others clinical conditions.Beside of its high mortality and morbidity, the outcomes of both these patients were good.
Pola Sensitivitas Isolat Klinis Bakteri Gram Negatif Multiresisten Obat Terhadap Fosfomisin dari Beberapa Rumah Sakit Kota Pekanbaru Dewi Anggraini; Atya Nasmah; Fauzia Andrini
Jurnal Ilmu Kedokteran Vol 13, No 1 (2019): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.232 KB) | DOI: 10.26891/JIK.v13i1.2019.28-35

Abstract

Over the last few years, there has been a decrease in amount of effective antibiotics, coincide with the lack of new antibiotics relevant for the treatment of Gram negative multi-drug resistant organisms infections. This problem can be overcome by the assessment and re-introduction of old antibiotics such as fosfomycin. Fosfomycin is a broad spectrum antibiotic that is bactericidal. This study aimed to find out the sensitivity pattern of clinical isolate multi-drug resistant Gram negative bacteria to fosfomycin with descriptive cross sectional method. The sample used in this study was clinical isolates collection of Microbiology Laboratory Faculty of Medicine, University of Riau from Hospitals in Pekanbaru. The result showedsensitivity to fosfomycin Escherichia coli producing ESBL (88%), Klebsiella pneumoniae producing ESBL (95%), Acinotobacter baumannii resistant meropenem (27%), Pseudomonas aeruginosa resistant meropenem (36%) and K.pneumoniae resistant meropenem (70%). Fosfomycin can be used as alternative therapy for infections caused by Gram-negative Multi-drug resistant organisms.
Bakteri dan Multiresisten Obat (Multi Drugresistance) pada Pasien dengan Kateter Urin di RSUD Petala Bumi Pekanbaru Rita Endriani; Dewi Anggraini; Rachmaliza Rachmaliza; Rika Wandari
Jurnal Ilmu Kedokteran Vol 10, No 2 (2016): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (80.724 KB) | DOI: 10.26891/JIK.v10i2.2016.121-131

Abstract

Patients with urinary catheter have an increased risk to get bacteriuria that could be develop to urinary tract infection(UTI). The aim of this study was to know sensitivity pattern and detection of ESBL in bacteria that isolated from urinof patient with urinary catheter more than 48 hours at Petala Bumi Hospital Pekanbaru. Thirty urin spesiments wasgrowthed in blood agar and MacConkey, incubated for 18 – 24 hours. Identification bacteria was done by some ofbiochemical test, sensitivity test was done by Kirby Bauer method, and ESBL detection done by double disc method.Predominantly bacteria isolated was Gram negative (90%). Gram-negative bacteria was 77.7% sensitive tochloramphenicol and fosfomycin. Gram-positive bacteria was 100% sensitive almost all antibiotic tested. Based onscreening test, this study found E. coli (40%) and Klebsiella sp, Acinetobacter sp and Pseudomonas sp (20%) werepossible produce ESBL, but ESBL was not found based on confirmatory test.
Tingkat Akseptabilitas dan Tolerabilitas Cairan Pencuci Tangan Formula World Health Organization (WHO) yang Digunakan Mahasiswa Kepaniteraan Klinik Senior di RSUD Arifin Achmad Provinsi Riau Dewi Anggraini; Insan Fitriyani; Tuti Restuastuti
Jurnal Ilmu Kedokteran Vol 9, No 1 (2015): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.714 KB) | DOI: 10.26891/JIK.v9i1.2015.27-32

Abstract

Health Care Associated Infection (HCAI) is one of the leading cause of mortality and morbidity in hospital and otherhealth care facilitiy. Hand hygiene is the main way to reduce incidence of HCAI. World Health Organization (WHO)recommends alcohol-based handrub because it is more acceptable and tolerable than other hand hygiene products.WHO has identified formulations for the local preparation. This was a descriptive study aimed to determine theacceptability and tolerability of WHO recommended handrub formulation. The subjects of the study were 40 seniorclerkships in Arifin Achmad Hospital, Riau Province, from Surgery, Obstetrics and Gynecology, and Internal MedicineDepartment. Each respondent was given WHO-recommended handrub formulation used for three days. On the firstday, the observer distributed handrubs being tested. After 3 days of consecutive use of the product, participantscompleted the questionnaire and the observer evaluate the condition of participants’ hands. We used WHO’squestionnaire to evaluate acceptability and tolerability level. The results of this study showed that WHO-recommendedhandrub formulation had good acceptability for its application, colour, smell, irritation, ease of use, speed of drying,and overall evaluation but had a less rate of acceptability for its textures and drying effect. WHO-recommendedhandrub formulation had good tolerability.