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The Effectiveness of Anti-Inflammatory Cream Galenic Preparations Based on Snail Seromucoid, Durian Peel Extract Polysaccharides and Chitosan in the Wound Healing Process (In Vivo) Harti, Agnes Sri; Sutanto, Yusup Subagio; Agustin, Wahyu Rima; Putriningrum, Rahajeng; Irdianty, Mellia Silvy; Saelan, Saelan; Ardiani, Nurul Devi
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.876

Abstract

Development of galenic preparation formulations that can be used to make anti-inflammatory cream preparations. Snail seromucoid contains glycoproteins, mannose carbohydrates, glucose, N-acetyl muramic acid and the α-1 globulin-oromucoid fraction which functions as a bioimmunostimulator. Durian peel (Durio zibethinus L.) contains a polar polysaccharide polymer compound such as D-galacturonic acid which has anti-microbial properties. Chitosan is a polymer compound resulting from derivatization of chitin which has antimicrobial polycationic properties; biodegradable, and biocompatible with animal body tissue. The aim of the research was to examine the effectiveness of a galenic anti-inflammatory cream preparation based on snail seromucoid, durian skin extract, and chitosan for healing acute and chronic wounds in vivo. The research method is experimental research, namely the effectiveness of anti-inflammatory galenic cream preparations made from snail seromucoid, durian peel extract and chitosan on various types of wounds in vivo. Analysis of observation data using the one way anova test. A galenic preparation based on a combination of 2% snail seromucoid, 2% durian peel extract polysaccharide and 2% chitosan ratio 1:1:1 is effective in the healing process based on the formation of granulation tissue thickness in incision injuries, hot objects injuries, second degree burns and ulcers. diabetes. The bioformulation galenic preparation of 2% snail seromucoid, 2% polysaccharide of durian peel extract; 2% chitosan and their combination with ratio 1:1:1 is effective as an anti-inflammatory galenic cream preparation so that it can be applied for healing chronic wounds, acute wounds and diabetic ulcers.
Synbiotic Soygurt Tempe Extract as A Functional Beverage Harti, Agnes Sri; Irdianty, Mellia Silvy; Muhlishoh, Arwin; Sutanto, Yusup Subagio
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.1124

Abstract

Synbiotic tempeh extract soyghurt is a Krenova (creative and innovative) food product because it is novelty and unique as healthy and safe food, functional food, fun for diet and one for all. The result of probiotic fermentation of Lactic Acid Bacteria (LAB) and based on synbiotic tempeh extract (rice bran and chitosan) which has multifunctional anti-hyperglycemia and anti-hypercholesterolemia properties. Research objective: to analyze the effectiveness of synbiotic tempeh soyghurt as a functional drink. The research method analyzes the nutritional content and quality of synbiotic tempeh soygurt products which refer to SNI 7552:2009 concerning flavored fermented milk. Data analysis used bivariate and multivariate Anova tests. The Hedonic test results showed a semi-solid texture, white color, synbiotic tempeh extract aroma, sour taste in the formulation with the addition of 15% skim milk, 1% chitosan, 1:1 ratio LAB starter mix and 5% inoculum. The results of physical chemical and mycobiological quality tests show that the synbiotic tempeh extract meets the quality test as a functional drink.
EFEKTIFITAS BIBLIOTERAPI TERHADAP PENINGKATAN KUALITAS HIDUP PADA PASIEN DENGAN DIABETES MELLITUS PADA KELOMPOK PROLANIS KARTASURA Listrikawati, Martini; Harti, Agnes Sri
Journal of Advanced Nursing and Health Sciences Vol. 2 No. 2, Agustus 2021
Publisher : Universitas Kusuma Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes Mellitus (DM) is a carbohydrate, protein, and fat metabolism disorder marked with hyperglycemia or blood glucose increase due to an abnormality of insulin secretion or decreased work performance of insulin. One of the handlers of Diabetes Mellitus is exercise. Low impact aerobic gymnastics is a gymnastics with low to moderate intensities, easy-to-do movements, injury-free movements, rhythmic movements, non-jerking movements, and rare sudden movement. Breathing relaxation is a breathing exercise which consists of abdomen breathing and purse lip breathing to reduce stress. The objective of this research is to investigate the effect of low impact aerobic gymnastics and deep breathing relaxation on blood sugar level of the diabetes mellitus elderly at Anggrek Integrated Health Post of Kartasura. This research uses quantitative method with a quasi-experimental research design with a pre-test and post-test approach without control group design. The result of the Wilcoxon’s Test shows that the p-value was 0.000 which was less than 0.05, meaning that the administration of low impact aerobic gymnastics and deep breathing relaxation could reduce the blood sugar level of the diabetes mellitus elderly. Thus, the low impact aerobic gymnastics and deep breathing relaxation had an effect on the blood sugar level of the diabetes mellitus elderly at Anggrek Integrated Health Post of Kartasura.