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HUBUNGAN SPIRITUAL DENGAN KUALITAS HIDUP PASIEN HIV/AIDS Syahrul Handoko Nainggolan; Ratna Dewi; Christina Magdalena T.Bolon; Rostinah Manurung; Sarmaida Siregar; Nixson Manurung
Jurnal Ilmiah Keperawatan IMELDA Vol. 11 No. 2 (2025): Jurnal Ilmiah Keperawatan IMELDA
Publisher : Program Studi S1/DIII-Keperawatan Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jikeperawatan.v11i2.1960

Abstract

The body can cause a decrease in the immune system, which can lead to AIDS. HIV/AIDS sufferers oftenexperience various complex problems in all aspects, including biological, psychological, social, andspiritual aspects. Spiritual problems that often arise in sufferers include blaming God, refusing toworship, disturbances in worship, and spiritual distress. Spiritual distress will impact their healthcondition in the form of a decreased quality of life because they have not accepted their illness and thetreatment that must be undergone. The purpose of this study was to determine the relationship betweenspirituality and the quality of lifeof HIV/AIDS sufferers at the RSU Imelda Pekerja IndonesiaMedan.This type of research is a quantitative approach with a cross-sectional research design. The sample in thestudy was determined by non-probability sampling with a purposive sampling technique of 111 HIV/AIDSpatients. Data analysis used the chi-square test. The results of the study indicate a relationship betweenspirituality and the quality of life of HIV/AIDS patients. It is recommended that the hospital use this asinformation and basic data regarding howspirituality applies to the quality of life of HIV/AIDS patientsso that the hospital can make policies to provide better services to HIV/AIDS patients undergoingtreatment atRSU Imelda Pekerja IndonesiaMedan.
Effectiveness of Styrax Paralleloneurus Extract as Anti-Inflammatory Agent on Incision Wounds in Male White Mice (Mus Musculus) Meriani Herlina; Noradina Noradina; Bernita Silalahi; Ratna Dewi; Syahrul Handoko Nainggolan; Ali Asman; Ririn Mariska Sitanggang
Proceeding of the International Conference on Health Sciences and Nursing Vol. 1 No. 1 (2024): June : Proceeding of the International Conference on Health Sciences and Nursin
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ichsn.v1i1.45

Abstract

Incision wounds are characterized by tissue damage or loss caused by sharp objects. Inflammation is the body's protective response to infection, irritation, or injury, marked by redness, heat, swelling, pain, and tissue dysfunction. Styrax paralleloneurus resin has potential wound-healing properties. This study aimed to investigate the anti-inflammatory effects of Styrax paralleloneurus extract on incision wounds in male white mice. Twenty-five mice were divided into five groups: positive control (Betadin), negative control (Vaseline), and three groups receiving 5%, 10%, and 15% Styrax paralleloneurus extract concentrations. Incision wounds (1cm x 0.2cm) were created on the dorsal area. Wound length and closure were observed daily using calipers. ANOVA analysis revealed significant differences (p=0.138 > 0.05) among the extract concentrations, indicating a concentration-dependent anti-inflammatory effect. The 15% concentration demonstrated the fastest wound healing. Bioactive compounds, such as flavonoids, saponins, and terpenoids, likely contribute to the anti-inflammatory effects. This study supports previous research on Styrax paralleloneurus' wound-healing properties. The results suggest Styrax paralleloneurus extract as a potential phytotherapeutic agent for wound healing. Further clinical trials and stability testing are recommended to develop a phytopharmaceutical product. Future studies should investigate the extract's mechanism of action and potential interactions with other medications. Conclusion The 15% concentration of Styrax paralleloneurus extract exhibited the fastest anti-inflammatory effects on incision wounds in male white mice.Recommendations: Conduct clinical trials to assess the stability, efficacy, and safety of Styrax paralleloneurus extract for phytopharmaceutical product development.