Eko Hidayanto
Departemen Fisika, Fakultas Sains Dan Matematika Universitas Diponegoro Jl. Prof. Soedarto, SH, Tembalang, Semarang Telp./Fax. (024)74680822/(024) 74680822

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Journal : Journal of Physics and Its Applications

Dose Distribution 6 MV of X-Ray Photon Beam over Cerium Oxide Nanoparticles Solution Iis Nurhasanah; Hella Arofah; Agus Subagio; Eko Hidayanto; Tri Windarti
Journal of Physics and Its Applications Vol 3, No 1 (2020): November 2020
Publisher : Diponegoro University Semarang Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpa.v3i1.9316

Abstract

CeO2 nanoparticles are biomaterial that demonstrate potential as antioxidant and radioprotector for medical application. In this study, the radioprotector properties of CeO2 nanoparticles was evaluated by measuring absorbed dose of X-ray radiation. CeO2 nanoparticles were synthesized by precipitation and characterized using UV-Vis and FTIR spectrometers. CeO2 nanoparticle solution was prepared with various concentrations from 0.005 mg/mL to 0.06 mg/mL. The solution was exposed to 6 MV X-ray photon beam from medical linear acceleration with a source-to-surface distance of 100 cm and radiation dose of 2 Gy. The absorbed dose of X-ray by CeO2 nanoparticle solution was measured by an ion chamber detector. The absorbance peak at 301 nm observed in UV-Vis spectrum and absorbance peak at 854 and 492 cm-1 in the FTIR spectrum confirmed the formation of CeO2 nanoparticles. Radiation dose measurement exhibited dose reduction of CeO2 nanoparticles solution depend on concentration. CeO2 nanoparticle solution with concentration higher than 0.04 mg/mL showed potential application for radioprotector 6 MV of X-ray photon beam.
Characteristics of Bolus Using Silicone Rubber with Silica Composites for Electron Beam Radiotherapy Santi Yuli Astuti; Heri Sutanto; Eko Hidayanto; Gede Wiratma Jaya; Astri Suppa Supratman; Galih Puspa Saraswati
Journal of Physics and Its Applications Vol 1, No 1 (2018): November 2018
Publisher : Diponegoro University Semarang Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpa.v1i1.3914

Abstract

Bolus is a material that equal with the tissue and functions to increase the dose radiation in surface area in external radiotherapy, which uses electron beam. In this research, bolus was made using silicone rubber (SR) material, which was mixed with silicacomposites material. The bolus with a dimension of 12 x 12 x 0,5 cm3 was successfully made with a various amount of silica composite (2%, 4%, 6%). Bolus was then characterized using linear accelerator (LINAC) with an electron beam for percentage of surface dose (PSD) and using CT-Scan to measurement relative electron density (RED). The energy of electron beam used in this research was5 and 7 MeV. The result shows that RED value increased with increasing the amount of silica composite with higher RED value amounted to 1.186. PSD value increased with increasing the amount of silica composite, higher PSD value of energy in 5 and 7 MeV amounted 106.82% and 106.82% and 100.34%, respectively. The result certified that the silica composite material can increase the percentage of surface dose on electron beam radiotherapy.
Synthesis of Zn-Fe nanoparticles using pulse laser ablation as a contrast agent in magnetic resonance imaging Nurul Hikmantiyah; Eko Hidayanto; Ali Khumaeni
Journal of Physics and Its Applications Vol 2, No 1 (2019): November 2019
Publisher : Diponegoro University Semarang Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpa.v2i1.6458

Abstract

Synthesis of zinc oxide nanoparticles, iron oxide nanoparticles and Zn-Fe nanoparticles using pulse laser ablation method has been conducted. Experimentally, a pulse Nd:YAG laser (1064 nm, 7 ns, 35 mJ) was directed and focused on a metal plates of pure Zn and Fe, which are placed in the liquid medium of polyvinyl pyrrolidone (PVP). The PVP functions as a stabilizer agent. The results show that the produced nanoparticles have a spherical shape with an averaged diameter of Zn-Fe nanoparticles of 13 nm. FTIR and XRD test results of Zn-Fe nanoparticles show characteristics of Zn-Fe compounds. The examination of Zn-Fe nanoparticles as MRI contrast agents was carried out by varying the concentration of nanoparticles. Cenh calculation results showed the highest contrast enhancement occurred at a concentration of 1.25 mM with a value of 64.26% for T1 weighted images, and 81.52% for T2 weighted images. The SNR calculation results show the highest value at a concentration of 1.25 mM of 70.52 for T1 weighted images. The highest SNR value in the T2 weighted image at a concentration of 0.156 mM of 165.09.
Co-Authors Abdul Rofiq Achmad Chalid Afif Afrio Rika. R Agus Joko Prasetyo Agus Romadhon Agus Subagio Ahmad Pradana Alfia Hanim Ali Khumaeni Ana Aprilia Annisa Tenri Maya Anugrah Rahma Ari Wiganti Ardian Handoko Ari Bawono P Ari Bawono Putranto Ariij Naufal Arisa Dwi Sakti Astri Suppa Supratman Bambang Haris Suhartono, Bambang Haris Budi Muhammad AR Candra Ancila Choirul Anam AM Diponegoro Dewi A. Insiano Diah Dwiana Lestari Duandini, Ega Elin Nuraini Elvira Rizqi Widyanti Erna Mariani Etika, Eva Anggun Evi Setiawati Galih Puspa Saraswati Galih Puspa Saraswati Gani Gunawan Gede Wiratma Jaya H Hadiyanto Hella Arofah Heri Sugito Heri Sutanto Hidayatullah Hidayatullah I. Istadi Idam Arif Iis Nurhasanah Indras Marhaendrajaya Iva Nistiyanti Jhonwesly Manik Josepa ND Simanjuntak Jun Kawai K Sofjan Firdausi Lamtiyah Ikha Indriyana M Rizqi Aditya Rahman Mariatul Khiftiyah Miftahul Aziz Mohammad Haekal Mohd Hanafi Ali Muahamad Irsal Much. Azam Muchammad Azam, Muchammad Muhammad Irwanto Muhammad Nur Muharam Budi Laksono, Muharam Budi Nur Paramita Nira Mulyono Nurul Hikmantiyah Nurulita, Syaphira Faza Pandji Triadyaksa Poppy Intan Tjahaja Poppy Intan Tjahaja Puput Khusnaiatul Putri Parmitasari Putu Sukmabuana Rafli Filano Rahmawati Hidayah Rini Shintawati Salimatul Litasova Sanggam Ramantisan Sanggam Ramantisan Sanggam Ramantisan Santi Yuli Astuti Singgih Wibowo Sri Murni Susila Wardaya, Susila Takashi Yamamoto Teruo Tanabe Tiffany Rahma Novestiana Tina Melinda Tri Windarti Tunggul Drajat Mulatomo Ukhti Lailun Nisa Very Richardina Wahyu Setia Budi Wahyu Tri Cahyanto Yoyon Wahyono Yoyon Wahyono Zaenal Arifin