Claim Missing Document
Check
Articles

Found 16 Documents
Search

Halal enzymatic cosmetic ingredients: The role of enzymes in ingredients selection Dwicesaria, Maheswari Alfira; Safithri, Mega; Andrianto, Dimas; Purwanto, Ukhradiya Magharaniq Safira
Halal Studies and Society Vol. 1 No. 1 (2024): January 2024
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/hass.1.1.16-19

Abstract

The rising demand for halal products, especially within the cosmetics industry, has increased the need for cosmetic products to comply with Islamic laws. One of the challenges in achieving halal certification is the determination of the source of the active ingredients used in cosmetic products, such as enzymes. According to Islamic laws, enzymes derived from pigs or other animals that are not slaughtered are not considered halal. To ensure that the enzymes used in cosmetics are derived from halal sources, it is necessary to use enzymes generated from microorganisms through fermentation, provided that the raw materials and growth medium comply with Islamic laws. Additionally, halal cosmetics must meet regional and international standards, including the Indonesian Ulema Council’s Fatwa and the Malaysian Cosmetic and Personal Care Standards. This research provides a comprehensive review of the role of enzymes in selecting halal compliance cosmetic ingredients, focusing on the source of enzymes as a means of assessing the halalness of cosmetic products. It is essential to utilize halal enzymes such as those derived from plants to provide Muslim consumers with assurance when using cosmetic products.
Agronomic and metabolite profile of Cymbopogon citratus utilizing the black soldier fly (Hermetia illucens) bioconverted compost Hanifati, Qisthina; Azizah, Annisa Nur Wahida; Firdaus, Muhamad Fajar; Purwanto, Ukhradiya Magharaniq Safira; Iman, Ramadhan Nur; Andrianto, Dimas; Sulistiyani
Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Vol. 52 No. 3 (2024): Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy)
Publisher : Indonesia Society of Agronomy (PERAGI) and Department of Agronomy and Horticulture, Faculty of Agriculture, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24831/jai.v52i3.57086

Abstract

The black soldier fly (BSF) maggot, a bioconversion agent for organic waste, can generate stable materials like compost. Lemongrass (Cymbopogon citratus), recognized for its numerous health benefits, is the subject of this research. The primary objective of this study was to assess the impact of applying BSF maggot bioconversion compost on the bioactive compound profile in the ethanol extract of lemongrass plants. Lemongrass cultivation was conducted in Sindangjaya Village, Cipanas, West Java, Indonesia, employing a randomized complete block design with a single factor. The single factor was the type of fertilizer, namely: control (P1), organic manure fertilizer (P2), and maggot fertilizer (P3). The introduction of BSF maggot bioconversion compost to the growth medium significantly affected the plant height (at 4, 6, 8, 10, and 12 weeks after planting) and wet weight (including stems, leaves, roots, and shoots). Ethanol extraction and identification with LCMS/MS (Liquid Chromatography–Mass Spectrometry/Mass Spectrometry) instruments revealed 48 compounds. Each treatment group (P1, P2, and P3) contained 37, 30, and 35 compounds, respectively. These compounds consisted of various groups, including amino acids, terpenoids, alkaloids, quinolines, carbohydrates, methoxyphenol, benzodioxole, diphenylmethane, and steroids. Keywords: bioactive; BSF frass; extraction; lemongrass
Potensi ekstrak maggot lalat tentara hitam Hermetia illucens (Linnaeus) dalam regulasi mekanisme antioksidan selular dan antiradang: Kajian in silico: The potential of black soldier fly Hermetia illucens (Linnaeus) maggot extracts in the regulation of cellular antioxidant and anti-inflammatory mechanisms: In silico study Sulistiyani; Firdaus, Muhamad Fajar; Sigiro, Ria Heni; Nawangsih, Abdjad Asih; Purwanto, Ukhradiya Magharaniq Safira; Andrianto, Dimas
Jurnal Entomologi Indonesia Vol 20 No 3 (2023): November
Publisher : Perhimpunan Entomologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5994/jei.20.3.223

Abstract

The potential of black soldier fly (Hermetia illucens (Linnaeus), BSF) maggots as the source of biopharmaca, has not been extensively studied. This research aimed to identify bioactive compunds in BSF maggot extract that potentially activate antioxidant signaling mechanism. BSF maggots fed with vegetable waste were extracted based on maceration method with water, methanol, and acetone as solvents. Forty bioactive compounds were identified by liquid chromatography-mass spectrometry: 15 were in the aqueous extract, 13 were from methanolic extract, and 12 were in the acetone extract. Most of those compounds (90%) were having high bioavailability score (= 0.55 or more) and relatively low toxicity (500 mg/Kg<LD50<5000mg/Kg BW). Molecular docking predicted that there were 26 bioactive compounds potential to activate cellular antioxidant signaling through activation of NRF2 transcription factor, better than the commercial NRF2 activator. The aqueous extract compound with PubChem CID: 73775828 was the best one that inhibited NRF2 signaling by binding to Keap-1 protein (PDB ID: 6FFM) with Gibbs free energy (ΔG) = -6.08 Kcal/mol and dissociation constant (Kd) = 3.58 í— 10-5 µM. Whereas inhibition of inflammation via NF-kappa B signaling was shown by an aqueous extract compound verpacamide A which bound inhibitor NF-kappa B kinase (IKK2) (PDB ID: 4KIK) with ΔG = -5.024 kcal/mol; Kd = 0.207 í— 103 µM. This potency was better than that of aspirin. In conclusion, BSF maggot extracts are source of biopharmaca with potential cellular antioxidant and anti-inflammatory activity.
Analisis Profil Metabolit Sekunder Ekstrak Etanol Brokoli (Brassica oleracea var. italica) pada Pemupukan Biokonversi Maggot Black Soldier Fly Purwanto, Ukhradiya Magharaniq Safira; Sulistiyani; Azizah, Anisa Nur Wahida; Rosyidah, Rara Annisaur
Current Biochemistry Vol. 12 No. 2 (2025)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.12.2.3

Abstract

Brokoli (Brassica oleracea var. italica) merupakan sayuran fungsional yang diketahui mengandung berbagai senyawa bioaktif dengan potensi nutrisi dan farmakologis yang penting. Penelitian ini bertujuan untuk memprofilkan senyawa bioaktif ekstrak brokoli yang dibudidayakan dengan perlakuan pemupukan berbeda, yaitu kontrol, pupuk kandang, dan pupuk biokonversi maggot black soldier fly (BSF). Sampel brokoli diekstraksi menggunakan etanol 80%, kemudian dianalisis dengan LC-MS/MS untuk mengidentifikasi dan mengkuantifikasi komposisi metabolit. Hasil penelitian menunjukkan bahwa perlakuan pupuk biokonversi maggot menghasilkan pertumbuhan tanaman yang lebih baik, meliputi tinggi tanaman, jumlah daun, biomassa segar dan kering, serta persentase berbunga dibanding perlakuan lain. Selain itu, perlakuan ini juga menghasilkan metabolit yang lebih beragam dengan kelimpahan lebih tinggi, terutama golongan fenolik, terpenoid, piridazin, dan indol. Beberapa senyawa utama yang teridentifikasi antara lain Indole-3-Propionic Acid dan N(1),N(8)-Bis(Coumaroyl)Spermidine(1+), serta turunan klorofil seperti pyropheophorbide-a yang ditemukan dengan kelimpahan signifikan. Temuan ini menunjukkan bahwa pupuk biokonversi maggot BSF mampu meningkatkan pertumbuhan sekaligus profil metabolit sekunder brokoli, sehingga berpotensi sebagai strategi pemupukan ramah lingkungan untuk meningkatkan kualitas nutrisi dan fungsional tanaman ini. 
Inovasi Pangan Berbasis Tempe sebagai Upaya Pemberdayaan Masyarakat untuk Tumbuh Kembang Anak Menuju Indonesia Emas 2045 Kurniasih, Rini; Safithri, Mega; Ambarsari, Laksmi; Kurniatin, Popi Asri; Purwanto, Ukhradiya Magharaniq Safira; Andrianto, Dimas; Falah, Syamsul; Rosyidah, Rara Annisaur; Dwicesaria, Maheswari Alfira; Hudayanti, Martini; Lestari, Ayu; Rahman, Syabilla Aulia; Pratiwi, Anggita Aziz; Ambarsavitri, Rahmadhani
Qardhul Hasan: Media Pengabdian kepada Masyarakat Vol. 12 No. 1 (2026): Qardhul Hasan: Media Pengabdian kepada Masyarakat
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/qh.v12i1.22074

Abstract

Indonesia menghadapi tantangan besar dalam mewujudkan generasi yang sehat, cerdas, dan produktif menuju Indonesia Emas 2045, dengan prevalensi stunting nasional yang masih mencapai 19,8% pada tahun 2024. Peningkatan gizi sejak dini melalui pangan lokal bergizi tinggi seperti tempe, sebagai sumber protein nabati, merupakan solusi yang efektif. Program pemberdayaan masyarakat di Desa Cipalaha, Garut, melibatkan ibu dengan anak usia 0–5 tahun, ibu hamil, serta kader Posyandu dan PKK. Kegiatan meliputi penilaian status gizi anak, edukasi gizi dan stunting, pelatihan pembuatan nugget tempe dan sari kedelai, serta evaluasi melalui kuesioner orang tua, wawancara, dan uji organoleptik. Hasil menunjukkan 24% balita tergolong pendek atau sangat pendek, dan seluruh anak di atas lima tahun memiliki berat badan kurang, menandakan kekurangan energi kronis. Tingkat pendidikan, pekerjaan, dan pendapatan orang tua berpengaruh kuat terhadap risiko stunting. Program ini berhasil meningkatkan pengetahuan, keterampilan, dan motivasi peserta dalam memproduksi serta mengonsumsi olahan tempe bergizi tinggi dengan tingkat penerimaan yang baik. Temuan ini menegaskan pentingnya inovasi pangan lokal dan pemberdayaan masyarakat dalam mendukung pertumbuhan anak dan tujuan Indonesia Emas 2045.
Comparative Analysis of Phenolic, Flavonoid, and Antioxidant Activity in Green, Black, and White Tea Kombucha Suantari, Ni Gusti Ayu Made Dewi; Purwanto, Ukhradiya Magharaniq Safira; Safithri, Mega
Indonesian Journal of Human Nutrition Vol. 12 No. 2 (2025)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2025.012.02.4

Abstract

This research explored how varying tea substrates (green, black, and white) affected the phenolic content, flavonoid content, and antioxidant activity of kombucha fermented with SCOBY. Four samples were prepared, including a control (no tea) and kombucha made from green, black, and white tea bases. The results showed that black tea kombucha had the highest levels of antioxidant compounds and activity. The DPPH assay revealed that black tea kombucha exhibited the highest antioxidant activity; a percent inhibition of 88.285 ± 2.196% and an IC50 value of 30.835 ± 1.340 µL/ml. Additionally, black tea kombucha had the highest total phenolic content (921.282 ± 38.075 mg GAE/L) and total flavonoid content (421.818 ± 24.052 mg QE/L). The type of tea used significantly impacted the final total phenolic content, total flavonoid content, and overall antioxidant activity of the resulting kombucha. Furthermore, the fermentation process also led to consistent decreases in pH and density across all samples. These comparative data offer valuable insight for optimizing tea-based kombucha formulations for functional food and beverage applications.