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The effect of bubble nasal continuous positive airway pressure application on saliva cortisol levels in full-term neonates Idrus, Noor Fadli; Febriani, Andi Dwi Bahagia; Alasiry, Ema
Paediatrica Indonesiana Vol. 64 No. 1 (2024): January 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.1.2024.22-7

Abstract

Background Neonates with respiratory distress are commonly treated with bubble nasal continuous positive airway pressure (nCPAP) and undergo many procedures that cause stress-induced pain. Salivary cortisol is a biomarker of alteration in the hypothalamic-pituitary-adrenal axis caused by repeated and long-term exposure to stress. Objective To analyze the effect of bubble nCPAP use on salivary cortisol levels in full-term infants. Methods This study used a one-group pre-test­–post-test design to compare salivary cortisol levels before and 30 minutes after bubble nCPAP application. Salivary cortisol was measured using an ELISA method. Pain was also assessed at the same time points using the Neonatal Infant Pain Scale (NIPS) score. We included infants of 37 0/7 to 42 6/7 weeks’ gestational age with respiratory distress necessitating bubble nCPAP application. Infants with birth weight of <2,500 grams, major congenital anomalies, an APGAR score of <5 at 5 minutes, shock, and infants who had undergone surgery were excluded. Results A total of 38 subjects participated in this study. Prior to bubble nCPAP application, median cortisol levels were significantly lower (1.65 ng/mL) than after bubble nCPAP application (6.8 ng/mL) (p value?). There were no significant differences in cortisol increase based on gender, type of birth, or salivary cortisol sampling time. There were significant differences in pain level after the 30-minute nCPAP application. Conclusion An increase in cortisol levels and pain scale scores during administration of bubble nCPAP indicates a pain response in full-term neonates; therefore, this procedure should be accompanied by pain or stress management.
Hubungan 8 OHdG (8-Hydroxy-2- Deoxyguanosin) Urin Neonatus dan Preeklamsia Tannur, Sebastianus; Lukas, Efendi; Mailoa, Johnsen; Alasiry, Ema; Irianta, Trika; Chalid, Maisuri T.
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.582

Abstract

Pendahuluan: Preeklamsia merupakan penyakit dengan berbagai teori (disease of theory) yang menggambarkan ketidakpastian patofisiologi dan penyebabnya. preeklamsia bukan hanya menyebabkan komplikasi terhadap maternal namun juga menimbulkan komplikasi terhadap janin, baik jangka pendek maupun jangka panjang. Peningkatan jumlah radikal bebas merupakan tanda terjadinya stres oksidatif pada kehamilan dengan preeklamsia. 8-OHdG adalah produk utama yang dibentuk dari radikal hidroksil pada residu guanine DNA.Metode: Penelitian ini merupakan penelitian analitik yang dikembangkan dengan desain penelitian cross-sectional. Sampel penelitian adalah neonatus yang lahir dari wanita hamil dengan dan tanpa didiagnosa preeklamsia. Pengambilan sampel dilakukan secara purposive sampling. dilakukan di Rumah Sakit Wahidin Sudirohusodo,dan rumah sakit jejaring pendidikan. Pengujian/running sampel dilakukan di unit Laboratorium Penelitian RSPTN Universitas Hasanuddin dengan metode Elisa. Data dianalisis dengan uji Chi squae, uji Mann whitney dan uji Kruskal wallis Hasil: Hasil penelitian yang telah dilakukan terdapat sebanyak 82 orang yang terbagi menjadi 41 orang sampel yang merupakan kelompok dengan preklamsia dan 41 orang sampel kelompok kontrol (normal). Berdasarkan hasil penelitian yang telah dilakukan mengenai kadar 8-OHdG urin neonatus (8-hydroxy-2- deoxyguanosin) pada kehamilan dengan Preeklamsia diperoleh nilai rerata kadar 8-OHdG urin neonatus pada kehamilan normal sebesar 3.79±1.99, sedangkan kehamilan dengan preeklamsia sebesar 14.25±16.81. uji statistik chi-square menunjukkan nilai p sebesar 0.00 dimana nilai p<0.05 yang artinya terdapat perbedaan kadar 8-OHdG urin neonatus terhadap kejadian preeklamsia dan ibu hamil normal pada penelitian ini. Kesimpulan: Terdapat perbedaan yang signifikan bermakna kadar 8-OHdG urin neonatus yaitu lebih tinggi kadar pada ibu hamil penderita preeklamsia daripada ibu hamil normal.Relationship Between 8 OHdG (8-Hydroxy-2- Deoxyguai›osine) in Neonate Urine and PreeclampsiaAbstractIntroduction: Preeclampsia is a disease with various theories (disease of theory) that describes the uncertainty of its pathophysiology and causes. Preeclampsia not only causes complications for the mother but also causes complications for the fetus, both short and long term. An increase in the number of free radicals is a sign of oxidative stress in preeclampsia. 8-OHdG is the main product formed from hydoxyl radicals in DNA guanine residues. Method: The research was an analytical study developed with a cross-sectional research design. The research sample was neonates born to pregnant women with and without a diagnosis of preeclampsia. The sample was determined by using purposive sampling technique carried out at Wahidin Sudirohusodo Hospital and educational network hospitals. Sample testing was carried out at Hasanuddin University RSPTN Research Laboratory unit using Elisa method. Data were analyzed using Chi square test, Mann Whitney test, and Kruskal Wallis test. Results: The research was carried out to 82 people who were divided into 41 samples in the group with preeclampsia and 41 samples in the control group (normal). Based on the results of research that has been carried out regarding the level of 8-OHdG in neonate urine (8-hydroxy-2-deoxyguanosine) in pregnancies with preeclampsia, the mean value of 8-OHdG level in neonate urine in normal pregnancies is 3.79 z 1.99, while the one in pregnancies with preeclampsia it is 14.25 z 16.81. The chi-square statistical test shows a p value 0.00 which p value <0.05, which means that there is a difference in the level of 8-OHdG in neonate urine in the occurrence of preeclampsia and normal pregnant women. Conclusion: There is a significant difference between the level of 8-OHdG in neonate urine, where the level is higher in pregnant women with preeclampsia than in normal pregnant women.Key words: 8-OHdG, neonate urine, preeclampsia
DETEKSI BAKTERI ATIPIKAL DARI SWAB NASOFARING PENDERITA SEPSIS NEONATORUM DI RS WAHIDIN SUDIROHUSODO MENGGUNAKAN POLYMERASE CHAIN REACTION (PCR) MULTIPLEKS Fadhilah; Sjahril, Rizalinda; Hatta, Mochammad; Bahagia, Dwi; Alasiry, Ema; Tarini, Ni Made Adi
Majalah Kesehatan Vol. 11 No. 4 (2024): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2024.011.04.1

Abstract

Sepsis neonatorum merupakan penyebab signifikan kematian neonatorum dan morbiditas jangka panjang. Infeksi bakteri atipikal berperan penting dalam sepsis neonatorum, namun sulit dideteksi dengan teknik mikrobiologi konvensional. Penelitian ini bertujuan untuk mendeteksi bakteri atipikal yaitu Chlamydia trachomatis, Mycoplasma pneumonia, Legionella pneumophila dan Ureaplasma urealyticum dengan Polymerase Chain Reaction (PCR) multipleks dari swab nasofaring pasien sepsis neonatorum yang dirawat di RS Wahidin Sudirohusodo Makassar. Penelitian ini merupakan penelitian observasional deskriptif pada neonatus dengan dugaan sepsis. Neonatus yang diduga sepsis akan diambil swab nasofaring kemudian diperiksa untuk mendeteksi Chlamydia trachomatis, Mycoplasma pneumonia, Legionella pneumophila dan Ureaplasma urealyticum menggunakan PCR multipleks. Pemeriksaan pasien sepsis neonatorum yang dirawat di NICU RS Wahidin Sudirohusodo Makassar menggunakan sampel swab nasofaring pada bulan September 2022 hingga Juni 2023 menunjukkan bahwa dari 60 pasien yang diperiksa swab nasofaring, 8 (13,33%) pasien terdeteksi infeksi tunggal bakteri atipikal  yaitu Mycoplasma pneumonia, Chlamydia trachomatis dan Legionella pneumophila serta 12 pasien (20%) di antaranya adalah infeksi multipel yaitu Mycoplasma pneumoniae dan Chlamydia trachomatis; Legionella pneumophila dan Chlamydia trachomatis; Mycoplasma pneumoniae, Chlamydia trachomatis dan Legionella pneumophila. PCR merupakan modalitas yang menjanjikan untuk mendeteksi bakteri atipikal dari swab nasofaring pasien sepsis neonatorum yang sulit diidentifikasi dengan teknik konvensional. Hal ini sangat berguna untuk memberikan terapi yang cepat dan tepat pada pasien sepsis neonatorum.
The Relationship Between Maternal and Fetal Factors with Anorectal Malformations Akbar, Puang Hafsari; Darussalam, Andi Husni Esa; Baharuddin, Baharuddin; Alasiry, Ema; Gani, Aziz Beru
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.2175

Abstract

Children with Anorectal Malformations (ARM) may experience lifelong physical impairment if not treated properly, and may adversely affect the personal and economic existence of affected individuals, as well as families and communities. The purpose of this study was to determine the factors of the incidence of anorectal malformations in neonates from maternal aspects and fetal aspects. By using research methods in the form of literature studies from the search results of 62 findings and 38 literature based on Electronic Based. The results of the discussion state that maternal risk factors that contribute to the incidence of ARM include exposure to teratogens such as cigarettes, alcohol, pesticides, drugs, and radiation during pregnancy. And fetal risk factors that contribute to the incidence of ARM include genetic and chromosomal factors, including related syndromes such as Down syndrome and VACTERL, which are the main causes of ARM.
The RELIABILITY AND ACCURACY OF EPICAM M AND RETCAM SHUTTLE COMPARED TO INDIRECT OPHTHALMOSCOPE IN DETECTION OF RETINOPATHY OF PREMATURITY Angky, Meiliaty Ariesta; Akib, Marliyanti N; Syamsu, Noor; Ichsan, Andi Muhammad; Muhiddin, Habibah S; Alasiry, Ema
International Journal of Retina Vol 6 No 2 (2023): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2023.vol006.iss002.233

Abstract

Introduction: In this study, we reported the performance of 2 retinal camera types on premature infants in Retinopathy of Prematurity (ROP) screening. Methods: Premature infants went through : (1) examination by a pediatric ophthalmologist using indirect ophthalmoscopy as a standard of reference; (2) digital imaging by a photographer using EpiCam M and RetCam shuttle. After a month, images were interpreted randomly and single-blinded by the same pediatric ophthalmologist (grader). Result: A total of 44 eyes from 22 premature infants were included in this study (ROP 11 subjects and non-ROP 11 subjects). Detection of ROP with EpiCam M had a moderate agreement (Kappa 0.502, p 0.009) and very good agreement with RetCam shuttle (Kappa 0.862, p <0.0001). Sensitivity, specificity, and accuracy of EpiCam M in detection of ROP were 80.95%, 69.56%, and 75%; RetCam shuttle 85.71%, 100%, and 93.18% respectively. Conclusion: Both EpiCam M and RetCam shuttle displayed significant agreement with indirect ophthalmoscope in detecting ROP. EpiCam M can potentially be allowed to be a viable low-cost alternative device for ROP screening in low resource environments but should be noted that EpiCam M has a high false positive rate which affects its specificity and accuracy rate. Some issues also need to be considered if using epiCam M in telemedicine includes frequent glare and longer duration of documentation
The Influence Of Edutainment-Based Education On Nutrition Lactation, Involution Uteri And Lochea Against Increased Knowledge, Attitudes And Behavior Of Puerperal Mothers Karnely, Karnely; Bukhari, Agussalim; Hidayanty, Healthy; Daud, Nurpudji Astuti; Alasiry, Ema
JKM (Jurnal Kebidanan Malahayati) Vol 10, No 8 (2024): Volume 10,No.8 Agustus 2024
Publisher : Program Studi Kebidanan Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkm.v10i8.17170

Abstract

Kembalinya alat-alat reproduksi seperti sebelum hamil membutuhkan kandungan gizi yang cukup bagi ibu. Makanan yang dikonsumsi ibu nifas harus bermutu, bergizi, dan cukup kalori. Dimana makanan yang dikonsumsi berguna untuk melakukan aktifitas, metabolisme, proses memproduksi ASI, sebagai ASI sendiri yang akan dikonsumsi oleh bayi untuk pertumbuhan dan perkembangan bayi, serta mempertahankan tubuh terhadap infeksi. Tujuan penelitian yaitu untuk mencari pengaruh edukasi berbasis edutainment tentang gizi laktasi, involusio uteri dan lokhea terhadap peningkatan pengetahuan, sikap dan perilaku ibu nifas. Metode Penelitian menggunakan Quasi Eksperimen dengan rancangan Non Equivalent Control Group Design. Di dalam desain ini observasi dilakukan sebanyak 2 kali yaitu sebelum dilakukan perlakuan dan sesudah dilakukan perlakuan. Pada kelompok intervensi dan kelompok kontrol masing-masing dilakukan pretest dan post test. Populasi dalam penelitian ini adalah seluruh ibu Nifas yang berada di RSKDIA Pertiwi dan RSKDIA Siti Fatimah Makassar sebanyak 5843 ibu nifas. Berdasarkan dari hasil perhitungan diatas didapatkan jumlah sampel sebesar 47 orang kelompok intervensi di RSKDIA Pertiwi Makassar dan 47 orang kelompok kontrol di RSKDIA Siti Fatimah Makassar dengan menggunakan teknik Purposive Sampling. Hasil penelitian menunjukkan bahwa terdapat pengaruh signifikan antara pengetahuan dengan edukasi berbasis edutainment tentang gizi laktasi, involusi uteri, dan lochea. Hasil penelitian menunjukkan bahwa terdapat pengaruh signifikan antara sikap dengan edukasi berbasis edutainment tentang gizi laktasi, involusi uteri, dan lochea. Hasil penelitian menunjukkan bahwa terdapat pengaruh signifikan antara perilaku dengan edukasi berbasis edutainment tentang gizi laktasi, involusi uteri, dan lochea. Saran kepada bidan yang bertugas di daerah khususnya di RSKDIA Pertiwi Makassar dan RSKDIA Siti Fatimah Makassar agar lebih meningkatkan kinerja serta perhatiannya dalam memberikan informasi tentang gizi laktasi, involusi uteri, dan lochea Kata Kunci : Edukasi, Gizi Laktasi, Involusio Uteri, Lokhea, Pengetahuan, Sikap dan Perilaku. ABSTRACT The return of reproductive organs before pregnancy requires sufficient nutritional content for the mother. The food consumed by the puerperal mother must be of high quality, nutritious, and sufficiently caloric. Where the food consumed is useful for activities, metabolism, and the process of producing breast milk, as its own milk that will be consumed by the baby for the growth and development of the baby, as well as defending the body against infections. The purpose of this study is to find the influence of edutainment-based education on lactation nutrition, uterine and lochia involution on increasing the knowledge, attitudes and behaviors of puerperal mothers. This study used the Quasi-Experimental design method with a Non-Equivalent Control Group Design. In this design, observations are carried out as many as 2 times, namely before treatment and after treatment. In the intervention group and the control group, pre-test and post-test were carried out, respectively. The population in this study was all Puerperal mothers who were at RSKDIA Pertiwi and RSKDIA Siti Fatimah Makassar as many as 5843 puerperal mothers. Based on the results of the calculations above, the number of samples was obtained by 47 intervention groups at RSKDIA Pertiwi Makassar and 47 control groups at RSKDIA Siti Fatimah Makassar using the Purposive Sampling technique. The results showed that there was a significant influence between knowledge and edutainment-based education about lactation nutrition, uterine involution, and lochia. The results showed that there was a significant influence between attitudes and edutainment-based education about lactation nutrition, uterine involution, and lochia. The results showed that there was a significant influence between behavior and edutainment-based education about lactation nutrition, uterine involution, and lochia. It is recommended to midwives who serve in the regions, especially at RSKDIA Pertiwi Makassar and RSKDIA Siti Fatimah Makassar to further improve their performance and attention in providing information about lactation nutrition, uterine involution, and lochia Key Words: Education, Lactation Nutrition, Uterine Involution, Lochia, Knowledge, Attitudes and Behaviors. 
The Effect of Storyline Therapy on The Development Language in 3 Years Age Children Ekawati, Erni Agit; Alasiry, Ema; Karo, Marni Br; Usman, Andi Nilawati; Tambaip, Titus
JURNAL KEBIDANAN Vol. 13 No. 2 (2023): Oktober 2023
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v13i2.8907

Abstract

Delays or disorders in children's speech and language in Indonesia are increasingly common, parents must be aware of their child's speech development, remembering that if these delays are not treated early, they will result in intelligence and behavioral disorders. The aim of this research is to determine the effect of storytelling therapy on language development in 3-year-old children at Posyandu Arumsari III Puskesmas Mranggen I. This type of research is a quantitative, quasi-experimental design type One Group Pretest Posttest design. The population of this study was all children under 3 years old at the Posyandu Arumsari III, Desa Kembangarum, Puskesmas Manggen 1, Kabupaten Demak, with a total of 26 children. The sample is determined by Federer's formula of 18 respondents. The sampling technique in this research is purposive sampling. Data analysis used univariate and bivariate analysis using Wilcoxon. Language development in children 3 years before storytelling therapy had an average of 29.2, with a median 29, after storytelling therapy had an average of 30.67, median 31. There was an effect of storytelling therapy on language development in children aged 3 years, obtained Pvalue 0.002 <0.05. There is an effect of storytelling therapy on language development in children aged 3 years. The results of this study are expected that mothers can do storytelling therapy at least 3 times a week to stimulate children's language development.
Application of Self-Reflection Using Reflective Journal on Oxytocin Massage Skills in Diploma Three Midwifery Students Arbie, Rina Sulisthia; Budu, Budu; Ahmad, Mardiana; Bukhari, Agussalim; Alasiry, Ema; Usman, Andi Nilawati
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1180

Abstract

Midwifery is a profession based on women-centered and evidence-based care through the provision of mutually respectful professional relationships and partnerships. To train students' skills, repeated learning is needed, learning can be sourced from experiences such as doing self-reflection by keeping a reflective journal. This research aims to analyze the effect of applying self-reflection using a reflective journal on oxytocin massage skills. This research is an experimental research using a one-group pretest-posttest group design approach, taking samples using a simple random sampling technique. The research population was all level III students in a bivariate analysis using the Friedman ANOVA test. The results showed that the pretest mean value was 59.28 increasing to 79.50 in the first posttest and 83.38 in the second posttest with a p-value <0.05, which means that there is an effect of applying reflective journals using reflective journals on oxytocin massage skills. Having students write reflective journals is a great way for them to learn new concepts. This approach is also useful for lecturers to get feedback on the concepts being studied by students. The use of reflective journals will guide students to analyze what they have and do not know about the material being studied and how to overcome the obstacles encountered so that learning goals are achieved and foster independent learning in students.