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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JURNAL FARMASIMED (JFM) MONSU'ANI TANO Jurnal Pengabdian Masyarakat Jurnal Farmagazine Jurnal Ilmiah Medicamento Jurnal Insan Farmasi Indonesia Journal of Fundamental and Applied Pharmaceutical Science Jurnal Abdiraja International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET) Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
Megawati, Sefi
Universitas Muhammadiyah A.R. Fachruddin
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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The Effect of Genjer Leaf Extract Ointment (Limnocharis flava) on Incision Wounds in Male New Zealand White rabbits Megawati, Sefi; Saru Noliqo Rangkuti; Ilmi Hidayat; Avianti Eka Dewi Aditya Purwaningsih
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/tfpm7z77

Abstract

Background: Incision wounds are a common type of open wound that require proper treatment to prevent infection and accelerate the healing process. The use of natural products as alternative wound therapy has been increasingly developed, one of which is yellow velvetleaf (Limnocharis flava), known to contain active compounds such as flavonoids, tannins, and saponins that have anti-inflammatory and wound healing properties. Objective: This study aimed to determine the effect of ethanol extract ointment of Limnocharis flava leaves on incision wound healing in male New Zealand White rabbits and to identify the most effective extract concentration. Methods: Limnocharis flava leaves were extracted using 70% ethanol by maceration with a ratio of 1:10, then formulated into ointments with concentrations of F1 (5%), F2 (7.5%), F3 (10%), F4 (negative control), and F5 (positive control using povidone-iodine). Results: The evaluation results showed that all ointment formulations met the physical requirements, including good homogeneity, stable form and color, pH compatible with skin pH, as well as optimal spreadability and adhesion. Observation of wound healing indicated an increase in the percentage of wound closure with higher extract concentrations and longer treatment duration. Statistical analysis using Two-Way ANOVA showed a p-value < 0.05, indicating a significant effect of extract concentration and duration of treatment on incision wound healing. Conclusion: Quantitatively, the 10% concentration group (F3) showed the highest percentage of wound closure and the fastest healing time compared to other groups, with effectiveness approaching the positive control. The 10% Limnocharis flava leaf extract ointment is the most effective formulation for accelerating incision wound healing.
Evaluasi Kualitatif dan Kuantitatif Penggunaan Antibiotik Pada Pasien Pneumonia Di Instalasi Rawat Inap RSUP Dr. Sitanala Megawati, Sefi; Ulis, Ulis; Yuniarto, Ari
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 22 No. 01 Juli 2025
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v22i1.20802

Abstract

Pneumonia adalah penyakit infeksi yang serius, yang disebabkan oleh berbagai faktor, dan untuk mencegah berkembangnya resistensi bakteri berdasarkan hal tersebut perlu dilakukan penelitian penggunaan antibiotik yang tepat dan rasional. Penelitian ini bertujuan untuk mengetahui ketepatan penggunaan antibiotik dan untuk mengetahui jenis dan jumlah penggunaan antibiotik dengan metode ATC/DDD pada pasien pneumonia rawat inap RSUP Dr. Sitanala Kota Tangerang. Dengan jumlah sampel 106 dari 145 populasi pasien, data dikumpulkan secara retrospektif dari laporan rekam medis dan dihitung berdasarkan rumus slovin. Dari hasil penelitian menunjukkan ketepatan penggunaan antibiotik pasien pneumonia RSUP Dr. Sitanala Kota Tangerang tahun 2019-2021 yaitu ketepatan indikasi 100%, pemilihan obat 100%, dosis 99,1%,  cara pemberian obat 100%, interval waktu pemberian obat 100%, dan lama pemberian antibiotik 11,32%, kemudian terdapat 8 macam antibiotik sebagai terapi penyakit pneumonia dimana kuantitas penggunaan 3 terbesar adalah Ceftriaxone 67,28 DDD/100 patient-days  (56,12%), Azithromycin 29,55 DDD/100 patient-days (24,65%), dan Levofloxacin 18,93 DDD/100 patient-days (15,79%).
Co-Authors Abdul Latif Junaedi Agil Restudiarti Anna Febriyanti Ari, Muhamad Ilham Ariadin Nurfi Arini Aprilliani Arini Aprilliani Arum Mawarni, Nur Indah Azzahra Fernanda Carolina, Febby Dania Maretiana Daulay, Meilyn A.K. Debya Wahyuningtyas Dewi Kurniasih Dinda Nisa S.Farm Djoko Wahyono Djoko Wahyono Elsa Agustyani Sukma Soleha Ervina Damayanti Oktavia Fathonah, Nuriyatul Fita Rahmawati Fita Rahmawati Fitri Hidayati Fitria Budi Utami Fitria Novfrianti Musrizal Ilmi Hidayat Luthfiyyatul Makiyyah M, Fajrin Noviyanto3 Meta Safitri Nia Wati Nita Rusdiana S.Farm., M.Sc, Apt Nur&#039;aini 4 Nuraini Nuraini Nuraini Nuraini Nuriyatul Fhatonah Nur’aini Nur’aini Purwaningsih, Avianti Eka Dewi Aditya Radooti Merlin Sagala Rangkuti, Saru Noliqo Rasydy, La Ode Akbar Reni Rahmawati Rini Rumantir Saru Noliqo Rangkuti Selpina Kurniasih Septiandu indransyah1 Setiawan, Abdul Aziz Sopiahani, Syifa Stiani, Sofi Nurmay Sujera, Lulu Sylvia, Diana Trisna Lestari Ulis, Ulis Wahyu Laras Setyani Yuniarto, Ari