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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Pharmaciana: Jurnal Kefarmasian JURNAL NASIONAL TEKNIK ELEKTRO Surya Medika: Jurnal Ilmiah Ilmu Keperawatan dan Ilmu Kesehatan Masyarakat Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Jurnal Pengabdian kepada Masyarakat Nusantara Indian Journal of Forensic Medicine & Toxicology Jurnal Kedokteran Universitas Palangka Raya Ahmad Dahlan Medical Journal Jurnal Medika: Karya Ilmiah Kesehatan Jurnal Forensik dan Medikolegal Indonesia
Wiraagni, Idha Arfianti
Department Of Forensic Medicine And Medicolegal, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada, Yogyakarta
Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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The correlation between the intensity of benzene exposure and complete blood count in the oil and natural gas company workers in East Kalimantan Ngatidjan, Idha Arfianti Wiraagni Iwan Dwiprahasto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (608.438 KB)

Abstract

Benzene is one of the dangerous chemical substances which can cause some health disturbances.Meta-analysis shows that people who are exposed to benzene have a leukemia risk of 1.4 timesmore than the ones who are not. The employees who are exposed to benzene for a long timehave a probability to receive the toxic effect from benzene. This study was conducted to evaluatethe relationship between the intensity of benzene exposure and blood count of employees in theoil and natural gas company in East Kalimantan. This research was conducted to 897 employeeswith case control design. The control group consisted of 521 subjects, whereas the case groupconsisted of 376 subjects. The subjects were 39.91±10.90 years old, with the working termbetween 1 to 36 years. Data were obtained from routine medical check-up and health riskassessment in 2007 – 2010. The independent variable namely benzene exposure and the dependentvariable namely result of blood count, were analyzed by using chi-square bivariat analysis.Intensity of benzene exposure was measured as OVM (Organic Vapour Monitor) for externaldosage and SPMA (S-phenylmercapturic acid) for internal dosage. The intensity of benzene in2007 was 1.07± 5.5 ppm (OVM) and average of SPMA was 11.54±5.28 ìg/g creatinine. Theintensity of benzene in 2009 was 4.15±13.6 ppm (OVM) and SPMA was 55.90±43.6 ìg/gcreatinine. The employees who were exposed to benzene had a risk of having a decrease ofeither hemoglobin, erythrocyte, thrombocyte, or leukocyte 1.71 times (95% CI, 1.18–2.48)compared with the control, although this reduction was still in the normal range (p= 0.004). Inconclusion, there was no relationship between the intensity of benzene exposure with the lowblood count of the employees.Keywords: benzene exposure - complete blood counts - oil and gas earth - mining - toxic effect
Karakteristik kasus pada Visum et Repertum di RSUP dr. Soeradji Tirtonegoro Klaten 2014-2016 wiraagni, idha arfianti; Widihartono, Edy
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.913 KB) | DOI: 10.12928/pharmaciana.v6i2.4214

Abstract

Since the opening of forensic services at RSUP dr. Soeradji Tirtonegoro Klaten since 2014, many forensic cases were handled. Based on the type of case, in the death cases, there are traffic accidents, crime, and other deaths. While in life cases, there are sexual violence, physical violence, and psychiatry. Research on basic characteristic patients’ are very important to do, especially for the police, government, hospital, and community. The purpose of this study was to determine the basic characteristic patients’ of Visum et Repertum in RSUP dr. Soeradji Tirtonegoro Klaten 2014-2016. This research was a cross-sectional study, with a total sampling method. The data were taken from Visum et Repertum during    2014 - March 2016. There were 242 life cases (124 women, 118 men), and 23 death cases (6 women, 17 men). Most patients were productive age (22-40 years old), with 33.5% life cases and 30.4% death cases. The highest number of life cases was physical abuse (109 cases; 45%), then all of death cases was accident. The highest profession of patients were students (30.6% in life cases), while in the death cases were private (43.5%). Head trauma was the most common injury in patients (45.9% life cases and 82.6% death cases). Most of the perpetrators were unknown people (77.7% life cases, as well as 82.6% of death cases). From both cases, the patients were from productive age, distribution of fatal wound was in the head, and the prepetators were unknown. These data are very important in educational process of society.
Validation of a Simple Extraction Procedure for Stimulants Identification from Human Plasma Idha Arfianti Wiraagni1-4, Mustafa Ali Mohd2 , Rusdi Abdul Rashid3, Didi Erwandi bin Mohamad Haron2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12041

Abstract

In this study, a novel LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) method wasdesigned using a simple extraction procedure that was scientifically developed to capture the most relevantstimulants, methamphetamine, MDA (3,4-Methylenedioxyamphetamine), MDMA (3,4-Methylenedioxymethamphetamine), and MDEA (Methyl diethanolamine). The LC-MS/MS method was validated usingUS FDA (United States Food and Drug Administration) guidelines, and all validation requirements weresatisfactory. This protein precipitation method was specifically developed for handling large numbers ofsamples with minimum cost and volume of sample. The developed method was accurate, precise, andreproducible for quantification of stimulant from human plasma. This pilot study enrolled 100 drug addictsto evaluate stimulant testing from plasma. Our findings found 47 cases with positive methamphetamine.This method may be valuable for stimulant blood screening for a large and varied population because of itsefficiency and economical aspects.
Prevalence and Injury Risk Factors based on Sleman Health and Demographic Surveillance System (HDSS) Data Idha Arfianti Wiraagni1 , Beta Ahlam Gizela1 , Majid2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12042

Abstract

Background: Injuries can occur in various groups of individuals with various risk factors and complications.Health problems due to injuries will put a burden on the victims’ individuals and families, health services,health insurance, even various parties related to the work productivity of victims. The analysis of injury riskfactors is an initial effort for injury prevention efforts which are expected to avoid reducing productivityand quality of life of individuals. Problem: Need to explore and analyze risk factors for injury, includingdemographic profile. Objective: The research to be carried out to determine the prevalence of injury casesand risk factors. Methods: This study used a cross-sectional observational design. The data used is secondarydata from HDSS Sleman. Research subjects were all injury cases recorded in the Sleman HDSS document.Statistical analysis was performed to calculate prevalence and see the strength of the relationship betweenrisk factors and the incidence of injury. Results: Males had an accident 54%, in 2017, it rose to 56%, and in2019 it dropped to 55%. In 2016, adults suffered 48% injuries, then decreased to 38% and 36% in the nextcycle. In 2016, the number of bruises and abrasions was 72%, and decreased in the next two cycles of 67%and 58%. Part of the body that was most often affected by injury during three cycles was the upper limb.Conclussion : Continued research on injuries and associated risk factors, needs to be done to create healthsurveillance data.
Case Study in Fatal Motorcycle Injury Patterns Budiatri Retno Noormaningrum; Idha Arfianti Wiraagni; Dhiwangkoro Aji Kadarmo
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16818

Abstract

Crash injury is one of the leading causes of premature death globally. In Indonesia, a motorcycle crash is themain cause of road traffic injuries. As a city with a high number of motorcycles, Yogyakarta needs the rightmitigation approach based on the local characteristics. The aim of this study was to evaluate the patterns ofinjury in a fatal motorcycle crash in Yogyakarta. Data were described from five dead motorcyclists that werebrought to the mortuary of Bhayangkara Hospital.
Using Sleman’s Verbal Autopsy Health and Demographic Surveillance Data to Distinguish Ways of Death Beta Ahlam Gizela; Idha Arfianti Wiraagni; Suhartini; Nurholis Majid Public
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15713

Abstract

Death can occur anywhere, with or without prior treatment by a healthcare professional. A good and complete death registry will meet the information needs. Such a registry will also enhance community safety efforts and policymaking in the health and population sectors. Analysis of risk factors, signs, and symptoms observed before death provides useful information for estimating diseases or causes of death. Verbal autopsy data must be explored in more depth to protect public law and improve health statistics.Methods: This research used observational design. Data obtained from the Health and Demographic Surveillance System of Sleman. Research subjects were all deaths recorded in verbal autopsy document from 2014-2018. Descriptive statistical analysis was used.Results: Differences in the proportion of gender from 2014-2017 were observed, where the number of women was higher than men. Most deaths were above 65 years of age. Most deaths were natural deaths. Unnatural deaths were caused by traffic accidents, drowning, murder, and others, with the most number of cases occurring in 2014 (12%). Indeterminate deaths occurred annually, with the most cases in 2017 (13%). Conclusions: Verbal autopsy has succeeded in distinguishing between natural and unnatural death.
The correlation between the intensity of benzene exposure and complete blood count in the oil and natural gas company workers in East Kalimantan Idha Arfianti Wiraagni Iwan Dwiprahasto Ngatidjan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (608.438 KB)

Abstract

Benzene is one of the dangerous chemical substances which can cause some health disturbances.Meta-analysis shows that people who are exposed to benzene have a leukemia risk of 1.4 timesmore than the ones who are not. The employees who are exposed to benzene for a long timehave a probability to receive the toxic effect from benzene. This study was conducted to evaluatethe relationship between the intensity of benzene exposure and blood count of employees in theoil and natural gas company in East Kalimantan. This research was conducted to 897 employeeswith case control design. The control group consisted of 521 subjects, whereas the case groupconsisted of 376 subjects. The subjects were 39.91±10.90 years old, with the working termbetween 1 to 36 years. Data were obtained from routine medical check-up and health riskassessment in 2007 – 2010. The independent variable namely benzene exposure and the dependentvariable namely result of blood count, were analyzed by using chi-square bivariat analysis.Intensity of benzene exposure was measured as OVM (Organic Vapour Monitor) for externaldosage and SPMA (S-phenylmercapturic acid) for internal dosage. The intensity of benzene in2007 was 1.07± 5.5 ppm (OVM) and average of SPMA was 11.54±5.28 ìg/g creatinine. Theintensity of benzene in 2009 was 4.15±13.6 ppm (OVM) and SPMA was 55.90±43.6 ìg/gcreatinine. The employees who were exposed to benzene had a risk of having a decrease ofeither hemoglobin, erythrocyte, thrombocyte, or leukocyte 1.71 times (95% CI, 1.18–2.48)compared with the control, although this reduction was still in the normal range (p= 0.004). Inconclusion, there was no relationship between the intensity of benzene exposure with the lowblood count of the employees.Keywords: benzene exposure - complete blood counts - oil and gas earth - mining - toxic effect
The analysis of cell damage of liver and kidney among alcoholics in Yogyakarta, Indonesia S Suhartini; Hendro Widagdo; Yudha Nurhantari; Idha Arfianti Wiraagni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 51, No 3 (2019)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.818 KB) | DOI: 10.19106/JMedSci005103201908

Abstract

Alcohol tends to disrupt the organs function of human body, even can cause serious and chronic damage. In Indonesia, the data on cell damage taken from organs including the livers and kidneys among alcoholics are still practically unknown. The aim of this study was to compare the differences of organs’ cell disturbance between alcoholics and non-alcoholics in Yogyakarta, Indonesia. A crosssectional study was conducted among 197 people in Yogyakarta, including 96 alcoholics and 101 non-alcoholics. The material of the study was taken from venous blood samples. A kinetic photometric test was conducted to obtain data on blood-chemical markers’ value of livers (SGOT, SGPT, and GGT), and kidneys (BUN and serum creatinine). The data werethen analyzed by Chi square test.From a total of 96 alcoholics, 83.6% are males and 16.4% are females who consumed alcohol for an average of 16 years, with 51.6% routinely consuming it daily. The kind of alcohol they consumed was single-brand (59.8%). Based on 25th percentile (GGT), on 50th percentile (SGOT, GGT), and on 75th percentile (SGPT, GGT), the alcoholics had higher proportion value of liver marker disturbance than non-alcoholics which was statistically significant (p<0.05). Based on the 50th and 75th percentiles, the alcoholics also had higher proportion value on kidney marker (BUN) damage than non-alcoholics which was statistically significant (p<0.05). There were significant differences in GFR values between males and females (p<0.05), males had kidney cell damage 7.9 times more than females. There was no significant difference in the value of GFR between alcoholics and non-alcoholics. In conclusion, the alcoholics hassignificantly higher proportion value of blood-chemical markers than that non-alcoholics. The GFR values between males and females are also significantly different, and males had kidney cell damage 7.9 times more than that of females.
Karakteristik kasus pada Visum et Repertum di RSUP dr. Soeradji Tirtonegoro Klaten 2014-2016 idha arfianti wiraagni; Edy Widihartono
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.913 KB) | DOI: 10.12928/pharmaciana.v6i2.4214

Abstract

Since the opening of forensic services at RSUP dr. Soeradji Tirtonegoro Klaten since 2014, many forensic cases were handled. Based on the type of case, in the death cases, there are traffic accidents, crime, and other deaths. While in life cases, there are sexual violence, physical violence, and psychiatry. Research on basic characteristic patients’ are very important to do, especially for the police, government, hospital, and community. The purpose of this study was to determine the basic characteristic patients’ of Visum et Repertum in RSUP dr. Soeradji Tirtonegoro Klaten 2014-2016. This research was a cross-sectional study, with a total sampling method. The data were taken from Visum et Repertum during    2014 - March 2016. There were 242 life cases (124 women, 118 men), and 23 death cases (6 women, 17 men). Most patients were productive age (22-40 years old), with 33.5% life cases and 30.4% death cases. The highest number of life cases was physical abuse (109 cases; 45%), then all of death cases was accident. The highest profession of patients were students (30.6% in life cases), while in the death cases were private (43.5%). Head trauma was the most common injury in patients (45.9% life cases and 82.6% death cases). Most of the perpetrators were unknown people (77.7% life cases, as well as 82.6% of death cases). From both cases, the patients were from productive age, distribution of fatal wound was in the head, and the prepetators were unknown. These data are very important in educational process of society.
Deskripsi Tingkat Kepatuhan Siswa Kelas 11 SMAN 3 Surakarta terhadap Pemakaian Alat Pelindung Kepala Wiraagni, Idha Arfianti; Natasya, Catherine; Basworo, Wikan; Priambodo, Dewanto Yusuf
Jurnal Medika : Karya Ilmiah Kesehatan Vol 8 No 2 (2023): Jurnal Medika Karya Ilmiah Kesehatan
Publisher : ITKES Wiyata Husada Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: Cedera akibat kecelakaan lalu lintas merupakan penyebab kematian terbanyak untuk anak-anak hingga dewasa muda. Lebih dari 70% kematian akibat kecelakaan lalu lintas terjadi pada pengguna sepeda motor, dengan penyebab utama berupa cedera kepala. Namun, masih banyak terjadi kelalaian penggunaan helm, khususnya pada kalangan remaja. Surakarta memiliki mobilitas penduduk tinggi sehingga rentan terjadi kecelakaan lalu lintas. SMAN 3 Surakarta dipilih sebagai lokasi penelitian karena terletak di 2 lokasi terpisah di tengah kota. Siswa kelas 11 diambil sebagai populasi penelitian karena mayoritas sudah berusia 17 tahun sehingga bisa memiliki SIM. Tujuan: Penelitian ini bertujuan untuk mengetahui tingkat kepatuhan siswa kelas 11 SMAN 3 Surakarta dalam memakai alat pelindung kepala berupa helm. Metode: Penelitian ini merupakan studi potong lintang, dengan data primer dari pengisian kuesioner oleh siswa kelas 11 SMAN 3 Surakarta pada bulan Maret 2023. Hasil: Diperoleh 237 data siswa kelas 11 SMAN 3 Surakarta. Mayoritas responden berusia 17 tahun (50,63%), perempuan (62,45%), memiliki sepeda motor (81,43%), tidak memiliki SIM C (88,61%), dan pengemudi (59,92%). Mayoritas responden selalu memakai helm (77,64%), menggunakan helm SNI (91,56%), memakai ikat dagu helm (81,86%), mengetahui manfaat helm (100%). Mayoritas responden (60,76%) memiliki skor total 12, yang menunjukkan perilaku pemakaian helm ideal dan mengetahui manfaat helm dalam mencegah cedera kepala akibat kecelakaan. Terdapat perbedaan signifikan kepatuhan pemakaian helm ideal pada variabel kepemilikan SIM C (p=0,004) dan sifat penggunaan sepeda motor (p=0,000). Kesimpulan: Mayoritas siswa-siswi SMAN 3 Surakarta memiliki tingkat kepatuhan pemakaian helm ideal tergolong patuh.
Co-Authors . Suhartini Alvita Widya Kustiawan Putri Andito, Akbar Ananda Artanti, Martiana Suciningtyas Tri Basworo, Wikan Beta Ahlam Gizela Bhima Nareshwara , Adhitya Budiatri Retno Noormaningrum Cahyadi, Salma Maharani Dewanto Yusuf Priyambodo Dhiwangkoro Aji Kadarmo Dwi Angesti Putri , Refly Edy Widihartono Eka Ganda Winata , I Putu Elvira Sukma Wahyuni Erwandi Mohamad Haron, Didi Firdaus Handayaningsih, Anastasia Evi Hendro Widagdo Hendro Widagdo Hidayat , Syukriadi Laksito, Aziz Pandu Mumahad Kurnia Natasya, Catherine Nisa Agustin Pratiwi Pelu Nurholis Majid Public Pidada, Ida Bagus Gede Surya Putra Poga, Adam Juan Priambodo, Dewanto Yusuf Putra Pidada, Ida Bagus Gede Surya Rusyad Adi Suriyanto Saputra Yadnya , Komang Setya Nugroho , Florantia Sharron Patricia Andara Suhartini Sukma Wahyuni , Elvira Supriyadi, Shea Sapphira Tri Artanti, Martiana Suciningtyas Trissanto, Stefanus Widihartono, Edy Widiningsih , Dewi Wikan Basworo Yudha Nurhantari