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Billy J. Kepel
Universitas Sam Ratulangi
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : JURNAL BIOMEDIK

 1 
Uji anti mycobacterium ekstrak bunga kembang sepatu (Hibiscus rosa sinensis L.) sebagai tumbuhan obat anti tuberkulosis Rendeng, Eirene F.; Kepel, Billy J.; Manampiring, Aaltje E.
JURNAL BIOMEDIK : JBM Vol 12, No 1 (2020): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.12.1.2020.27006

Abstract

Abstract: Besides as decorative flower and its benefit in hair growing, hibiscus flower (Hibiscus rosa sinensis L.) is also known for its antibacterial role. This study was aimed to obtain the inhibitory and killing potencies of hibiscus flower extract against Mycobacterium tuberculosis bacteria. This was a laboratory experimental study. Extract of hibiscus flower was obtained by using maceration technique with ethanol and then was prepared in several concentrations, as follows: 12.5%, 25%, 50%, 75%, and 100%. The extract was tested against M. tuberculosis by using spectrophotometer to obtain its maximum inhibitory and killing potencies. The results showed that concentrations of 50%, 75%, 100% of the hibiscus extract could inhibit the growth of M. Tuberculosis. Meanwhile, only concentration of 100% of the extract could kill the bacteria. In conclusion, the extract of hibiscus flower (Hibiscus rosa sinensis L.) could inhibit the growth of Mycobacterium tuberculosis and kill the bacteria.Keywords: Hibiscus rosa sinensis, inhibitory potency, killing potency, Mycobacterium tuberculosis Abstrak: Selain sebagai tanaman hias dan penyubur rambut, kembang sepatu (Hibiscus rosa sinensis L.) juga dikenal berefek antibakteri. Penelitian ini bertujuan untuk menentukan aktivitas daya hambat dan daya bunuh ekstrak ekstrak bunga kembang sepatu (Hibiscus rosa sinensis L.) terhadap bakteri Mycobacterium tuberculosis. Jenis penelitian ialah eksperimental laboratorium. Ekstrak bunga kembang sepatu diperoleh melalui cara maserasi dengan etanol. Konsentrasi ekstrak 12,5%, 25%, 50%, 75%, dan 100% diujikan terhadap bakteri M. tuberculosis dengan menggunakan alat spektrofotometer untuk mengetahui daya hambat dan daya bunuh ekstrak terhadap M. tuberculosis. Hasil penelitian mendapatkan ekstrak bunga kembang sepatu pada konsentrasi 50%, 75%, dan 100% dapat menghambat pertumbuhan M. tuberculosis dan juga dapat membunuh M. tuberculosis pada konsentrasi 100%. Simpulan penelitian ini ialah ekstrak bunga kembang sepatu (Hibiscus rosa sinensis L.) dapat menghambat pertumbuhan dan membunuh bakteri Mycobacterium tuberculosis.Kata kunci: Hibiscus rosa sinensis, daya hambat, daya bunuh, Mycobacterium tuberculosis.
GAMBARAN PENGETAHUAN MASYARAKAT DESA WIAU LAPI TENTANG STOMATITIS AFTOSA REKUREN Wololy, Jefrianto; Kepel, Billy J.; Mintjelungan, Christy N.
JURNAL BIOMEDIK : JBM Vol 5, No 1 (2013): JURNAL BIOMEDIK : JBM Suplemen
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.5.1.2013.2637

Abstract

Abstract: Recurrent aphthous stomatitis (RAS), commonly known among Indonesian people as "sariawan", is an oral mucosal disease which most often affects people. Based on the clinical symptoms, there are three recognized types of RAS, namely: minor RAS as the most common type, major RAS, and herpetiform RAS. Knowledge about RAS is very useful in the prevention and treatment of RAS. This was a descriptive study with a cross-sectional design. Samples were 75 Wiau Lapi villagers who filled in the questionnaires and were selected by using simple random sampling. This study aimed to reveal the knowledge of the villagers of Wiau Lapi about recurrent aphthous stomatitis. The results showed that the knowledge of the villagers of Wiau Lapi about RAS tested with the questionnaire consisting of 11 questions obtained a percentage of 63.8%. Conclusion: Most villagers of Wiau Lapi had good knowledge about recurrent aphthous stomatitis. Keywords: knowledge, recurrent aphtous stomatitis.     Abstrak: Stomatitis aftosa rekuren (SAR) atau yang umum dikenal masyarakat Indonesia sebagai “sariawan”, merupakan penyakit mukosa oral yang paling sering diderita manusia. Sampai saat ini terdapat tiga jenis SAR yang dikenal, dengan gejala klinis masing-masing, yaitu: SAR minor sebagai jenis yang paling umum, SAR mayor, dan SAR herpetiformis. Pemahaman yang baik tentang SAR akan sangat bermanfaat ketika penderita berusaha menangani SAR. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan masyarakat Desa Wiau Lapi tentang stomatitis aftosa rekuren. Penelitian ini menggunakan metode deskriptif dengan cross-sectional design yang dilakukan selama satu bulan. Sampel ialah 75 penduduk desa Wiau Lapi yang mengisi kuesioner dan diseleksi dengan menggunakan simple random sampling. Hasil penelitian menunjukkan bahwa pengetahuan masyarakat Desa Wiau Lapi tentang SAR yang diuji dengan kuesioner yang meliputi 11 pertanyaan mencapai persentase sebesar 63,8 %. Simpulan: Pengetahuan masyarakat Desa Wiau Lapi mengenai SAR sudah tergolong baik. Kata kunci: pengetahuan, stomatitis aftosa rekuren.
Co-Authors Aaltje E. Manampiring Aaltje Manampiring Amelia Wulandari Antonius P. Rumengan Aves A. Septuaginta Bahter, Julia V.F. Bato, Donny Christian Bella Lestari, Bella Billy Senduk, Billy Budi Ratag, Budi Budiarso, Fone D.H. Christy N. Mintjelungan Deviwanti Batara, Deviwanti Dina Rombot Dinar A. Wicaksono Fatimawali . Felomina Jempormase, Felomina Fitria Angela Umar Fona Budiarso Friscasari Kundaian Gabriela V.Ch Walewangko Gerungan, Yizreel Y. Glenaldy Rondonuwu Grace Debbie Kandou Grace Korompis Heryudi J. J. Soelama, Heryudi J. J. Hidayat, Muh. I. Jeanette I. Ch. Manoppo Jefrianto Wololy Jimmy Posangi Jootje M. L. Umboh Jootje M.L Umboh, Jootje M.L Karamoy, Eunike M. Killing, Maykel Krisma Juliana Mazniati Tolombot Krista V. Siagian Mantiri, Desy M. H Momuat, Heski Deswan Monica Ruus, Monica Ningsi Hadji Ali Nova Hellen Kapantow Olii, Nindhy P. S. Anindita Palandi, Oktavia R. Y. Pantow, Natalia M. Polii, Reiner C. Prasetio, Nathanael F. Pratiwi, Ageng Ingrit Randy Lande, Randy Ratu, Belinda D. P. M. Rendeng, Eirene F. Rene C. Kepel, Rene C. Rizky, Irfan Irianto Runtunuwu, Thea Sagemba, Pascal G. Sefty S. Rompas Sekeon, Sekplin A.S. Simak, Valen Simak Siringo-Ringo, Aurian Fricilia Sompie, Intan P.R. Stevy B. Najoan Sumakul, Grivit T. Sutanto, Stella Tampi, Meiny Ledya Tandra, Hendry J.R. Ticoalu, Jolanda P. Valentino Rakasiwi, Valentino Vanessa J. T. Seran, Vanessa J. T. Wahyuni R. Ramadhani, Wahyuni R. Wico Silolonga Widdhi Bodhi Widhi Bodhi Wuisan, Teisly Monica Wulan G. Parengkuan, Wulan G. Wulan Palilingan, Wulan Yoas P. Simangunsong, Yoas P.