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Phytochemical Analysis and Determination of MIC and MFC of Cacao Leaves Extract (Theobroma cacao L.) against Malassezia furfur Lestari, Siti Marwah; Camelia, Leonyta; Rizki, Widya Twini; Pratama, Septa; Khutami, Chindiana; Amelia, Amraini; Rahmadevi, Rahmadevi; Andriani, Yuni
Jurnal Jamu Indonesia Vol. 9 No. 2 (2024): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v9i2.316

Abstract

Pityriasis versicolor is a disease caused by Malassezia furfur. One of the plants that can potentially act as antifungal is cacao leaves (Theobroma cacao L.), which contain several secondary metabolite compounds, including alkaloids, flavonoids, tannins, quinones, terpenoids, and saponins. This study aims to determine the phytochemical analysis and the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of cacao leaves ethanolic extract against M. furfur. Extracts were obtained by maceration using 70% ethanol and phytochemicals analysis using Herborne’s method. Furthermore, the extracts were made into concentrations’ variations of 3.125%; 6.25%; 12.5%; 25%; 50%; and 100% for testing antifungal activity, with 10% DMSO as negative control and 2% Ketoconazole and Itraconazole as positive controls. MIC was performed with liquid macrodilution method, and MFC was performed with spread method. The results of phytochemical analysis showed that the extract contained alkaloids, flavonoids, phenols, tannins, quinones, terpenoids and saponins. MIC value was obtained at concentration of 50% and MFC value was obtained at 100%. Cacao leaves ethanolic extract with concentration of 50% can inhibit M. furfur’s growth and with 100% can eliminate M. furfur.
Penguatan Eduwisata Hidroponik Barokah dan Inovasi Produk Sayur Amraini Amelia; Chindiana Khutami; Adria Wuri Lastari
Jurnal Medika: Medika Vol. 5 No. 1 (2026)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/5dvs2s42

Abstract

This community service program was conducted at the Barokah Hydroponic Group in Kenali Asam Atas Subdistrict, Jambi City, which operates an active hydroponic system but has not yet optimally utilized it as educational tourism or a source of value-added product development. The main challenges faced by the partner included the absence of durable processed vegetable products and the lack of standardized educational tourism management. This program aimed to strengthen hydroponic educational tourism and develop innovative vegetable-based processed products in the form of vegetable powder (simplisia) to enhance community capacity and economic potential. The implementation methods included preparation, socialization, training, application of simple technology, mentoring, and evaluation. Activities focused on producing vegetable powder from Brazilian spinach and common spinach, developing Standard Operating Procedures (SOP) for educational tourism, and providing initial mentoring for educational tourism implementation. The results indicated an improvement in partners’ knowledge and skills, as reflected by an increase in average pre-test scores from 60% to 82% in the post-test. In addition, the partners successfully produced value-added products and established structured guidelines for managing educational tourism activities. This program is important as a sustainable model for strengthening hydroponic-based educational tourism and local product innovation
EDUKASI BIJAK PENGGUNAAN OBAT SAAT PUASA PADA MASYARAKAT TUGU KERIS SIGINJAI KOTA JAMBI Rahmat Hidayat; Amraini Amelia; Kristy Mellya Putri; Rahmad Fitrianto; Menrisal Menrisal; Chindiana Khutami; Putri Dewi Anggraini; Dwi Rahmawati; Talitha Salshabilla Azzahra; Sa'adatul Karimah; Egis Monica
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 7 No. 3 (2026): Inpress Vol. 7 No. 3 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v7i3.57352

Abstract

Mayoritas penduduk di Indonesia beragama Islam dan menjalankan ibadah puasa pada bulan Ramadhan. Selama menjalankan puasa terjadi perubahan pola makan dari tiga kali sehari menjadi dua kali, yaitu saat berbuka puasa dan sahur. Perubahan pola makan ini juga berpengaruh terhadap waktu dan aturan penggunaan obat bagi masyarakat yang sedang menjalani terapi pengobatan. Kurangnya pemahaman mengenai cara penggunaan obat yang tepat selama berpuasa dapat menyebabkan penggunaan obat yang tidak sesuai sehingga berpotensi menurunkan efektivitas terapi. Oleh karena itu, diperlukan edukasi kepada masyarakat mengenai penggunaan obat yang bijak dan tepat selama menjalankan ibadah puasa. Kegiatan pengabdian kepada masyarakat ini dilaksanakan di kawasan Tugu Keris Siginjai Kota Jambi dengan metode sosialisasi langsung kepada masyarakat menggunakan media leaflet sebagai sarana edukasi. Selain itu, kegiatan ini juga disertai dengan pembagian takjil kepada masyarakat sebagai bentuk kepedulian sosial. Hasil kegiatan menunjukkan bahwa masyarakat memberikan respon yang positif terhadap kegiatan edukasi yang dilaksanakan. Hal ini terlihat dari antusiasme masyarakat dalam mengikuti kegiatan, partisipasi aktif dalam sesi diskusi, serta adanya interaksi antara tim pelaksana dan masyarakat. Secara umum kegiatan pengabdian masyarakat ini berjalan dengan baik dan diharapkan dapat meningkatkan pengetahuan masyarakat mengenai penggunaan obat yang tepat dan aman selama menjalankan ibadah puasa.
Pola penggunaan obat antihipertensi pada pasien lanjut usia Ulfa Maya Sari; Amraini Amelia; Darma Satria
JOURNAL OF Qualitative Health Research & Case Studies Reports Vol 6 No 5 (2026): May Edition 2026
Publisher : Published by: Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/quilt.v6i5.3281

Abstract

Background: High blood pressure, or hypertension, is a non-communicable disease with a significant prevalence among the elderly. This condition is also a significant trigger for various cardiovascular health disorders. Purpose: To identify patterns of antihypertensive medication use among elderly patients. Method: This study used a non-experimental descriptive approach through a retrospective cross-sectional design, utilizing information sourced from patient medical records. The sample size for this study was determined using a purposive sampling method, with 100 elderly hypertensive patients. Results: The analyzed data, including field findings, confirmed that the majority of respondents were female (58%) and aged 60–74 years (77%). Stage 2 hypertension was the most common category (41%). Antihypertensive medications with stage 2 hypertension were the most common category (41%). The most commonly used antihypertensive medication was amlodipine 10 mg from the Calcium Channel Blocker (CCB) class, at 54%. Combination therapy with two drugs was used more frequently (55%) than monotherapy. This study involved 100 elderly hypertensive patients. Conclusion: The majority of hypertension treatment options in the elderly involve amlodipine and a combination regimen of two drugs.   Keywords: Amlodipine; Drug Use Pattern; Elderly; Hypertension.   Pendahuluan: Penyakit tekanan darah tinggi atau hipertensi tergolong sebagai salah satu jenis penyakit tidak menular yang memiliki tingkat persebaran kasus yang signifikan di kalangan lansia. Kondisi ini juga menjadi pemicu signifikan bagi munculnya berbagai gangguan kesehatan pada sistem kardiovaskular. Tujuan: Untuk mengidentifikasi pola penggunaan obat antihipertensi di kalangan pasien lanjut usia. Metode: Penelitian ini menggunakan pendekatan deskriptif non-eksperimental melalui skema cross-sectional yang bersifat retrospektif dengan memanfaatkan informasi yang bersumber dari catatan rekam medis pasien. Penentuan sampel dalam studi ini dilakukan melalui metode purposive sampling dengan jumlah 100 pasien hipertensi lansia. Hasil: Data yang dianalisis meliputi temuan di lapangan mengonfirmasi bahwa responden terbanyak adalah perempuan dengan proporsi (58%) dan berusia 60–74 tahun (77%). Hipertensi derajat 2 merupakan kategori terbanyak (41%). Obat antihipertensi dengan hipertensi derajat 2 merupakan kategori terbanyak (41%). Obat antihipertensi yang paling banyak digunakan adalah amlodipin 10 mg dari golongan Calcium Channel Blocker (CCB) sebanyak 54%. Terapi kombinasi dua obat lebih sering digunakan (55%) dibandingkan dengan terapi tunggal. Penelitian ini melibatkan 100 pasien lansia hipertensi. Simpulan: Mayoritas manajemen pengobatan hipertensi pada lansia menggunakan amlodipin serta penerapan skema kombinasi dua jenis obat.   Kata Kunci: Amlodipin; Hipertensi; Lansia; Pola Penggunaan Obat.
Correlation of Body Mass Index and Menstrual Length to Hemoglobin Levels in Adolescent Women Yesi Mustika Sari; Amraini Amelia
Nursing and Health Sciences Journal (NHSJ) Vol. 4 No. 1 (2024): March 2024
Publisher : KHD-Production

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53713/nhsj.v4i1.308

Abstract

Anemia is a condition in which the body experiences a lack of hemoglobin levels in the blood. In Indonesia, those who experience anemia the most are teenagers with a prevalence of 30-55%, meanwhile the proportion of anemia in women is higher than in men with a prevalence of 23.9%. Anemia in teenagers increases pregnant women's risk of chronic energy deficiency, stunting, low birth weight and other health problems. Body mass index (BMI) as an indicator of nutritional status and duration of menstruation is one of the factors causing anemia in adolescent girls, so this research aims to determine the relationship between BMI and duration of menstruation on hemoglobin levels in adolescent girls. Method: The research used a quasi-experimental design using the Nonequivalent Control Group Design model by selecting 60 young women who met the inclusion criteria as a sample. Results: Pearson correlation analysis shows that BMI is not correlated with hemoglobin levels with a p-value of 0.717, while the length of menstruation is correlated with hemoglobin levels in adolescent girls with the strength of the relationship being sufficient with an r-0.331 p-value of 0.010, which means that the longer the adolescent girls menstruate, the longer they menstruate. the lower the hemoglobin level.
FORMULASI CLAY MASK STICK DARI MINYAK BIJI WORTEL (Daucus carota L.) SEBAGAI ANTI AGING Amraini Amelia; Jumarni; Chindiana Khutami; Helman Kurniadi
Jurnal Penelitian Farmasi Indonesia Vol 15 No 1 (2026): Jurnal Penelitian Farmasi Indonesia (JPFI)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v15i1.2228

Abstract

Masalah penuaan dini akibat paparan sinar UV dan radikal bebas mendorong pengembangan produk perawatan kulit yang efektif dan aman dari bahan alami. Salah satunya adalah minyak biji wortel (Daucus carota L.) yang kaya vitamin A, E, beta-karoten, serta asam lemak esensial yang bermanfaat sebagai antioksidan, menjaga kelembapan, elastisitas, dan kesehatan kulit. Penelitian ini bertujuan untuk merumuskan Clay Mask Stick berbahan dasar minyak biji wortel dan mengevaluasi sifat fisik, stabilitas, iritasi, serta efektivitasnya sebagai anti-aging. Metode penelitian meliputi pembuatan empat formula (F0-F3) dengan variasi konsentrasi minyak biji wortel (0%, 3%, 6%, 9%). Evaluasi dilakukan melalui uji organoleptis, homogenitas, pH, daya sebar, waktu kering, daya potong, uji stabilitas (cycling test), uji iritasi, serta uji efektivitas peningkatan kelembapan, kadar minyak, dan kelembutan kulit menggunakan skin analyzer pada sukarelawan. Hasil penelitian menunjukkan seluruh formula stabil secara fisik, memiliki pH sesuai rentang aman (4,5–6,5), homogen, tidak menimbulkan iritasi, dan memiliki waktu kering serta daya sebar yang sesuai. Formula dengan konsentrasi 6% minyak biji wortel (F2) menunjukkan hasil terbaik dalam meningkatkan kelembapan, kadar minyak alami, dan kelembutan kulit secara signifikan. Dengan demikian, Clay Mask Stick minyak biji wortel berpotensi dikembangkan sebagai produk anti-aging praktis dan aman, mendukung pemanfaatan komoditas lokal dalam industri kosmetik
Hubungan Penggunaan Obat Tradisional Dengan Kualitas Hidup Pada Anak Muda Penderita Hipertensi di Kota Jambi Qonita Salsabila; Yuni Andriani; Amraini Amelia
Science and Education Journal (SICEDU) Vol 5 No 2 (2026): Science and Education Journal 2026
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sicedu.v5i2.395

Abstract

Hypertension “is one of the non-communicable diseases that is currently increasingly found, not only in the elderly but also in young people. In addition to undergoing therapy using antihypertensive drugs, some hypertension sufferers use traditional medicine as a complementary therapy to help control blood pressure. This study aims to analyze the relationship between the use of traditional medicine and the quality of life in young people with hypertension in Jambi City. This study uses a quantitative method with an analytical observational design through a cross-sectional comparative approach. The number of samples in this study was 50 respondents selected using the WHOQOL-BREF questionnaire, then analyzed using the SPSS program through the Independent Sample T-Test and multiple linear regression. The results of the study showed a difference in the quality of life between respondents who used traditional medicine and respondents who did not use traditional medicine with a significance value of 0.018 (p <0.05). However, the results of multiple linear regression analysis show that the variables of traditional medicine use, age, gender, duration of hypertension, and blood pressure simultaneously do not have a significant relationship with the respondents' quality of life, with a significance value of 0.054 (p>0.05).