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All Journal Majalah Kedokteran Bandung Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Hasil Pengabdian Kepada Masyarakat JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Ihsan: Jurnal Pengabdian Masyarakat Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Jurnal Pandu Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Ance Roslina
Universitas Muhammadiyah Sumatera Utara
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Journal : Majalah Kedokteran Bandung

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Antibacterial Activity of Mangrove Leaves Extract (Rhizopora Apiculata) Against Salmonella typhi Growth Nurfadly, Nurfadly; Harahap, Sevani Ayu; Roslina, Ance; Sarirah, Munauwarus
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4092

Abstract

Mangrove leaves (Rhizopora apiculata) contain antibacterial chemical compounds with antibacterial properties against various pathogens. Salmonella typhi, the causative agent of thyphoid fever, triggers a systemic infectious disease that can lead to complications and deaths if not treated properly.  This study aimed to screen the phytochemical content of R. apiculata leaf extract, evaluate its antibacterial activity against S. typhi, and determine the optimal inhibitory concentration. Leaves were collected from the Sicanang mangrove forest in Belawan, North Sumatra, Indonesia, and extracted using the maceration method with 96% ethanol.  Antibacterial effectiveness was assessed using disc diffusion method by measuring the zone of inhibition after exposure to mangrove leaf extract at concentrations of 40%, 60%, 80%, and 100%, with chloramphenicol as a positive control, to determine the most effective concentration for inhibiting the growth of Salmonella typhi. The results of the study showed that there were differences in inhibition zones in each group. Mangrove leaves extract at a concentration of 100% is the most effective in inhibiting the growth of Salmonella typhi compared to 80%, 60%, and 40% concentrations.
Co-Authors Amelia Eka Damayanti Amelia Eka Damayanti Aminuyati ANNISA . ANNISA ANNISA Annisah, Rati Atika Dwiyanti AULIA RAHMI Ayunda Pratiwi L. Tobing Ayunda Pratiwi L. Tobing DANDI NOVTIARDI Dian Erisyawanty Batubara DWINDA RAHMATUN AZHARI PINEM Dwiyanti, Atika FIRSTY DWI HIDAYATI SIRAIT Harahap, Habib Al Rasyid Harahap, Sevani Ayu Humairah Medina Liza Humairah Medina Liza Lubis IHAM HARIAJI Ilham Hariaji Isra Thristy KARINA RAMADHANI Karina Ramadhani Muhammad Al Anas Muhammad Devi Fauzan Rizki Mutiara Yusfah Putri MUTIARA YUSFAH PUTRI S NADHILAH SARI NASUTION NUR HALIZA RASYID Nurfadly, Nurfadly Oche Axena Yulhan Purwoningsih, Emni Putra, Kevin Rhesa Putri, Nabilah Triana RIDHA SAKINAH SOLIN Sarirah, Munauwarus SHAFIRA ROZAANDITA Siti Mulyani TITIN NURJANAH UTARI SEPTIA DHARMA Yenita Yenita Yulhan, Oche Axena