Article Per Year (5 Year)
p-Index From 2021 - 2026
2.735
P-Index
This Author published in this journals
All Journal Folia Medica Indonesiana Journal of Agromedicine and Medical Sciences Global Medical and Health Communication Jurnal Media Gizi Indonesia (MGI) Majalah Obstetri dan Ginekologi The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Oto Rhino Laryngologica Indonesiana Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Masyarakat Indonesia Narra J Archives of The Medicine and Case Reports Sasambo Journal of Pharmacy Jurnal Abdi Masyarakat Indonesia Jurnal Pengabdian Kesehatan Masyarakat
Mahrus A Rahman, Mahrus A
Departement Of Child Health, Dr. Soetomo General Hospital, Faculty Of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No. 6-8, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 26 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 26 Documents
Search

 1   2   3 
Deteksi Dini Penyakit Jantung Bawaan Melalui Pelatihan Webinar dan Screening Echocardiography di Kediri Mahrus A. Rahman; I Ketut Alit Utamayasa; Taufiq Hidayat; Teddy Ontoseno
Jurnal Pengabdian Masyarakat Indonesia Vol 3 No 4 (2023): JPMI - Agustus 2023
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.1244

Abstract

Penyakit jantung bawaan (PJB) merupakan penyakit bawaan lahir yang paling banyak menimbulkan kematian. Kurangnya pengetahuan pada tenaga kesehatan menjadi hambatan dalam pencegahan dan deteksi dini PJB. Kegiatan edukasi yang bertujuan untuk meningkatkan pengetahuan tenaga kesehatan dalam melakukan deteksi dini dan penanganan PJB di Kediri perlu dilakukan. Kegiatan ini meliputi pelatihan webinar dan screening echocardiography dengan peserta tenaga kesehatan di Kediri. Tingkat pengetahuan peserta dinilai dengan pre-test dan post-test. Selanjutnya dilakukan screening echocardiography oleh Dokter Spesialis Anak Konsultan Jantung. Webinar diikuti oleh 451 peserta. Skor rata-rata pre-test adalah 5,80/15 dan skor rata-rata post-test adalah 12,84/15. Sebanyak 29 anak dilakukan pemeriksaan echocardiography. Terdapat 19 (65,52%) anak yang didiagnosis dengan PJB asianotik, 4 (13,79%) anak dengan PJB sianotik, dan 6 (20,68%) anak normal. Pelatihan webinar dapat meningkatkan pengetahuan tenaga kesehatan tentang deteksi dini PJB dan 79,31% anak yang telah dilakukan screening echocardiography didiagnosis dengan PJB di Kediri.
Is maternal pre-pregnancy Body Mass Index associated with type of Congenital Heart Disease in offspring? Nofita Fachryandini; Taufiq Hidayat; Ernawati Ernawati; Mahrus A Rahman
Majalah Obstetri & Ginekologi Vol. 31 No. 2 (2023): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I22023.80-85

Abstract

HIGHLIGHTS The most common CHD was atrial septal defect for acyanotic CHD and Tetralogy of Fallot for cyanotic CHD. There was no association between maternal pre-pregnancy BMI and type of CHD in offspring.   ABSTRACT Objectives: This study aimed to determine the association between maternal pre-pregnancy BMI and type of congenital heart disease (CHD) in offspring. Materials and Methods: This retrospective cross-sectional study involved all mothers of children with CHD who visited Pediatric Outpatient Unit at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2019. The maternal data were obtained from the KIA's (Maternal and Child Health) book or through anamnesis by telephone, while the offspring’s data were collected from medical records. The data were analyzed using the Chi-Square test. Significance was determined at a 5% level (p <0.05). Results: We studied 117 mothers of children with CHD. The most frequent maternal pre-pregnancy body mass index (BMI) was normal (BMI 17-23 kg/m2) accounting for 56.4% of the study population. The most common CHD was atrial septal defect (33.3%) among acyanotic patients and Tetralogy of Fallot (8.5%) among cyanotic patients. The Chi-Square test showed p=0.958 for the association between maternal pre-pregnancy BMI and type of CHD in offspring. Conclusion: There was no association between maternal pre-pregnancy BMI and type of CHD in offspring.  
Incidence and Predictors of Reperfusion Arrhythmia on STEMI Patients and Its Association with Infarct and Reperfusion Therapy Factors: A Cross-Sectional Study Fairuz Kamila, Rizqi Apsari; Budi Baktijasa Dharmajati; Mahrus A. Rahman; Bambang Herwanto
Archives of The Medicine and Case Reports Vol. 5 No. 1 (2024): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v5i1.450

Abstract

Reperfusion arrhythmia was one of the markers of reperfusion in acute myocardial infarction (AMI). However, as the study developed, there were controversial findings of the meaning of reperfusion arrhythmias as a marker of successful reperfusion or persistent ischemia. The study aims to analyze the occurrence of arrhythmia in patients with STEMI undergoing reperfusion therapy with primary PCI or thrombolytic at Dr. Soetomo General Hospital Surabaya. This study is a retrospective observational study with a cross-sectional design using medical records as a data source. The occurrence of arrhythmias in patients was observed within 24 hours after the reperfusion therapy procedure. A total of 82 STEMI patients undergoing reperfusion therapy were observed (78 primary PCI and 4 thrombolytic). The total rate of reperfusion arrhythmia beyond the first 24 hours after the procedure was 54.9% (n = 45). There was no significant association for the baseline clinical characteristics of patients with the risk of reperfusion arrhythmia except for the heart rate on admission (p-value=0.003). The choice of reperfusion therapy (thrombolytic or PPCI) and time to revascularization were also not significantly associated with the occurrence of arrhythmias. Infarct characteristics, including the location and the number of blood vessels diseased, also did not have a significant relationship with the incidence of arrhythmias. Reperfusion therapy remains, resulting in a higher incidence of reperfusion arrhythmias. The incidence of reperfusion arrhythmias may be influenced by various factors. Thus, close monitoring beyond the first 24 hours after reperfusion therapy is required.
Comprehensive in silico analysis of single nucleotide polymorphism and molecular dynamics simulation of human GATA6 protein in ventricular septal defect Hidayat, Taufiq; Irwanto, Irwanto; Rohman, Ali; Muhyiddin, Afrizal AA.; Putri, Safira NA.; Kurniawan, Dedy B.; Syaban, Mokhamad FR.; Firdaus, Theakirana; Rahman, Mahrus A.; Utamayasa, I KA.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1344

Abstract

Congenital heart disease (CHD) represents nearly one-third of congenital birth defects annually, with ventricular septal defect (VSD) being the most common type. The aim of this study was to explore the role of specific GATA binding protein 6 gene (GATA6) mutations as a potential etiological factor in the development of VSD through an in silico approach. Data were collected from the human gene databases: DisGeNET and GeneCards, with protein-protein interaction networks constructed via STRING and Cytoscape. Gene ontology and pathway enrichment analyses were conducted using DAVID, with data analysis in R with significance set at FDR p<0.05. Target single nucleotide polymorphisms (SNPs) of GATA6 were obtained from NCBI dbSNP, and non-synonymous single nucleotide polymorphism (nsSNP) effects were predicted using SIFT, PolyPhen-2, I-Mutant 2.0, Fathmm, MutPred 2.0, SNP&GO, and PON-P2. Conserved regions of GATA6 were analyzed using ConSurf, with functional classification, variant conservation, and stability changes evaluated in Google Colab. Multiple sequence alignment was performed using ClustalW. Mutation modeling and molecular dynamics analysis, using GROMACS, revealed that among 87 intersecting genes, 16 proteins were interconnected with GATA6, showing a centrality value of 0.4378. Gene ontology analysis highlighted atrioventricular canal development, protein-DNA complexes, and transcription factor regulation as key processes for cardiac development, especially in the ventricular septum. NsSNP and molecular dynamics analyses identified rs387906818 and rs387906820 as having the highest pathogenic potential for VSD due to amino acid structural changes.
Seminar Deteksi Dini Penyakit Jantung Bawaan pada Anak dengan Pemeriksaan Pulse Oxymetri dan Ekokardiografi di RSUD dr. Mohammad Zyn Sampang Utamayasa, I Ketut Alit; Rahman, Mahrus A.; Hidayat, Taufiq; Wicaksono, Henry; Nastiti, Prima Hari
Jurnal Abdi Masyarakat Indonesia Vol 4 No 6 (2024): JAMSI - November 2024
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.1354

Abstract

Penyakit jantung bawaan (PJB) merupakan salah satu penyakit kelainan bawaan yang sering terjadi dengan presentase 0,8% hingga 1,2% dengan angka kematian 81 kasus per 100.000 kelahiran hidup. Umumnya, PJB merupakan kelainan struktur jantung dan (atau) pembuluh darah besar yang muncul saat lahir. Kegiatan dari seminar ini bertujuan untuk memberikan pengetahuan dan pelatihan kepada tenaga medis tentang deteksi dini penyakit jantung bawaan yang dilanjutkan dengan pemeriksaan saturasi oksigen menggunakan pulse oxymetri dan ekokardiografi di Sampang, Madura, Jawa Timur. Metode seminar ini dilakukan melalui seminar disertai pelatihan deteksi dini PJB dengan peserta tenaga kesehatan di Madura. Seminar meliputi metode deteksi dini, diagnosis dan terapi, serta simulasi kasus PJB. Evaluasi berdasarkan Pre dan Post-test untuk melihat tingkat pengetahuan para peserta. Pemeriksaan Ekokardiografi dan Pulse Oxymeter dilakukan oleh dokter Spesialis Jantung Anak. Hasil dari kegiatan ini, terdapat 100 peserta yang mengikuti pelatihan seminar. Nilai rata-rata pre-test adalah 53,7/100 dengan hanya 2 peserta yang mendapatkan nilai sempurna. Di akhir seminar, rata-rata nilai post-test adalah 92,3/100 dengan 45 peserta yang akhirnya mendapatkan nilai sempurna. Dari hasil pemeriksaan, sebanyak 20 anak diperiksa dengan pemeriksaan ekokardiografi. 11 anak didiagnosis PJB asianotik, 1 anak didiagnosis PJB sianotik, dan 8 anak normal. Pada pemeriksaan oksimetri nadi, seluruh bayi mempunyai saturasi oksigen 95% atau lebih dan tidak terdapat perbedaan lebih dari 3% antara lokasi pra dan post ductal. Dengan diadakannya seminar dan pelatihan ini membuat para tenaga medis menjadi paham dan mengerti cara melakukan deteksi dini pada pasien anak dengan PJB.
The Correlation between Cardiac and Liver Function in Children with Heart Failure Utamayasa, I Ketut Alit; Wicaksono, Henry; Karyani, Enny; Nastiti, Prima Hari; Setyoboedi, Bagus; Rahman, Mahrus A.
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 3 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i3.2478

Abstract

The liver has a complex dual blood supply, which makes it more resistant to hepatocyte necrosis due to hemodynamic disturbances. Prior hemodynamic data has indicated that an elevation in right atrial pressure in patients with heart failure may result in aberrant cholestatic markers of liver function. This cross-sectional study examined the correlation between ejection fraction and liver function in 85 children (1–18 years) with congenital or acquired heart disease. Echocardiography assessed TAPSE, Tricuspid Regurgitation (TR), E/A ratio, and Left Ventricular Ejection Fraction (LVEF), while liver function was evaluated using total bilirubin and SGPT. Results showed a strong negative correlation between TAPSE and total bilirubin (p=0.001, r= -0.725) and a moderate positive correlation between tricuspid regurgitation and total bilirubin (p=0.001, r=0.548). The E/A ratio, LVEF, and total bilirubin showed weak correlations, while TAPSE and SGPT had a weak negative correlation (p=0.025, r= -0.243). No correlation was found between TR, E/A ratio, LVEF, and SGPT. A strong correlation existed between heart failure severity and total bilirubin (p=0.001, r=0.603), but not with SGPT. These results highlight the correlation between the severity of heart failure and liver impairment by indicating that decreasing right ventricular function correlates to elevated total bilirubin.
Co-Authors AGUS HARIANTO Ali Rohman Alit Utamayasa Alit Utamayasa Bagus Setyoboedi Bambang Herwanto Budi Baktijasa Dharmajati Budiono Budiono Chaq El Chaq Zamzam Multazam Cintya Dipta Dina Angelika Enny Karyani, Enny Ernawati Ernawati Evisina Hanafiati Frans Fachry Abda El Rahman Fairuz Kamila, Rizqi Apsari Fatchul Wahab Firdaus, Theakirana Henry Wicaksono Henry Wicaksono, Henry I Dewa Gede Ugrasena Irwanto Irwanto Juliana Juliana Kartika Darma Handayani Kartika Hardiyani Ketut Angga Aditya Putra Pramana Kurniawan, Dedy B. Lefi, Achmad Martono Tri Utomo Mia Puspitasari Muhyiddin, Afrizal AA. Nastiti, Prima Hari Nofita Fachryandini Nyilo Purnami Ovin Nada Saputri Putri, Safira NA. R Fatchul Wahabe Rina Elizabeth Rio Herdyanto Risa Etika, Risa Roedi Irawan Saraswati Dewi Sarmanu, Sarmanu Saskia Ratna Desita Sembiring, Yan Efrata Soebroto, Heroe Sunny Mariana Samosir Syaban, Mokhamad FR. Syamsul Arifin Taufiq Hidayat Teddy Ontoseno Utamayasa, I KA. Utamayasa, I Ketut Alit Vinny Yoanna Viskasari P. Kalanjati Wiwin Retnowati Yudi Her Oktaviono, Yudi Her Yusra Pintaningrum