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All Journal AL KAUNIYAH Biogenesis: Jurnal Ilmiah Biologi Al Ilmi Biota Bio Ilmi: Jurnal Pendidikan Journal of Biology Education Indonesian Journal of Biology Education Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Prosiding Seminar Nasional Biologi, Teknologi dan Kependidikan (Biotik) Conferences of Medical Sciences Dies Natalis
Delima Engga Maretha
Universitas Islam Negeri Raden Fatah Palembang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The effect of exposure to liquid air freshener on histological of the bronchial mice (Mus musculus) Warobi Warobi; Delima Engga Maretha; Asnilawati Asnilawati; Mashuri Masri
Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Vol 6 No 02 (2021): Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Publisher : Biology Education Department, IKIP Budi Utomo, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33503/ebio.v6i02.1219

Abstract

Air fresheners are products that contain chemicals aimed at reducing unpleasant odours in confined spaces. The use of synthetic air fresheners turns out to harm health because some of their leased Volatile Organic Compounds are classified as toxic compounds and are carcinogens. Air freshener enters the body through the inhalation process in the respiratory system. Modern air fresheners are available in liquid (aerosol) and gel forms. Air fresheners contain addictive substances and solvents such as 1,4-dichlorobenzene which can affect pulmonary function. The purpose of this study is to know the effect of exposure to liquid air freshener on the histology of bronchi of mice (Mus musculus). This study used 20 male mice (Mus musculus) consisting of 4 treatments with 5 replications. The research design is true experimental in the form of a post-test only control group with Completely Randomized Design (CRD). The post-test was done by observing the histological picture of the mice's bronchi after exposure to liquid air freshener given 3x/day for a period of P1 = 2 weeks, P2 = 4 weeks and P3 = 6 weeks. Quantitative data on bronchial histology was tested using the One Way ANOVA statistical test followed by the Post Hoc Tukey test. The results of the study found changes in the histology of the bronchi, thickening of the epithelial tissue of mice. Analysis of comparative data between the control and treatment groups statistically obtained p = 0.010 <0.05, meaning that there was a significant effect and change in the bronchial tubes exposed to liquid air freshener. Histologically there were differences in histology between the control and treatment groups. It was concluded that liquid air freshener had a significant effect on the histological picture of the mice's bronchi.
Biogenesis Mitokondria Delima Engga Maretha
Conferences of Medical Sciences Dies Natalis Vol. 1 No. 1 (2019): Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sr
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (891.568 KB)

Abstract

Mitokondria merupakan salah satu organel berperan penting dalam sistem organisme. Mitokondria memiliki fungsi yang beragam dan saling berhubungan, menghasilkan ATP, berperan pada proses biosintetik juga berkontribusi pada respons stres seluler seperti autofagi dan apoptosis. Mitokondria membentuk jaringan dinamis dan saling berhubungan yang terintegrasi erat dengan kompartemen seluler lainnya. Selain itu, fungsi mitokondria mempengaruhi fisiologi organisme dengan mengatur komunikasi antara sel dan jaringan. Oleh karena itu tidak mengherankan bahwa disfungsi mitokondria muncul sebagai faktor kunci dalam berbagai penyakit, termasuk gangguan neurodegeneratif dan metabolisme. Proses regenerasi sel mitokondria sangat mempengaruhi keberlangsungan dan fungsi mitokondria dalam kehidupan sel.
The Effect of Extract Papaya (Carica papaya) Seed on Aedes aegypti Larvae Mortality Nur Wahid; Delima Engga Maretha; Asnilawati Asnilawati
Indonesian Journal of Biology Education Vol 5, No 1 (2022): INDONESIAN JOURNAL OF BIOLOGY EDUCATION
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.815 KB) | DOI: 10.31002/ijobe.v5i1.5946

Abstract

Papaya plant is a plant originating from America with the scientific name Carica papaya. Papaya seeds contain flavonoids, glucotropaeolin, and phosphatidyl choline. Flavonoids are chemical compounds that have insecticidal properties. Flavonoids attack the nerves in several vital organs of insects, causing a weakening of the nerves, such as breathing and causing death. This study aims to examine the effect of papaya seed extract (Carica papaya) on the mortality of Aedes aegypti mosquito larvae and to determine the minimum inhibitory concentration of papaya (Carica papaya) seed extract required against Aedes aegypti mosquito larvae. The Aedes aegypti mosquito has a complete metamorphosis, and when it is in the larval stage, the Aedes aegypti mosquito has 4 phases, namely instar I, instar II, instar III, and instar IV larvae. The larvae used in this study were the larvae of the third instar Aedes aegypti mosquito. The research method used is a laboratory experimental method using a completely randomized design (CRD) where there are 4 treatments and 3 repetitions. The concentrations used in this study were 1 positive control, 10 ml, 30 ml, and 50 ml. The results were analyzed by One way ANOVA test followed by Post-Hoc LSD analysis. The results of the research that has been carried out show that the papaya seed extract (Carica papaya) which kills the most Aedes aegypti mosquito larvae is at a concentration of 50 ml, where in the first and second tests succeeded in killing 4 out of 5 larvae. In the last iteration managed to kill 5 out of 5 larvae. And it can also be seen that the minimum inhibitory concentration is at a concentration of 10 ml, where in 3 repetitions it can only kill 2 to 3 larvae from a total of 5 larvae. The 50 ml concentration is also the concentration that has the fastest effect, where on the fifth spray alone, there are already dead mosquitoes. While at a concentration of 10 ml, it takes a longer time, namely the seventh spray.
THE ANTIBIOTIC RESISTANCE AND THE ABILITY OF BACTERIATO PRODUCE -LACTAMASES Mashuri Masri; Joko Widodo; Ekafadly Jusuf; Delima Engga Maretha; Wahyuni Wahyuni
Prosiding Seminar Nasional Biotik Vol 10, No 2 (2022): PROSIDING SEMINAR NASIONAL BIOTIK X 2022
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh, Aceh, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (714.435 KB) | DOI: 10.22373/pbio.v10i2.15165

Abstract

Background : Accessibility of bacterial patterns and their sensitivity to pus can be utilized as a thought in giving anti-microbials observationally. Vale Sorowako Inco Hospital was located in mining region where health services were not as enormous as in huge cities but can still carry out free sensitivity tests without send them to a referral hospital. Methods: Antibiotics (Penicillin, cefuroxime, Ceftriaxone, and meropenem) were tried by dise diffusion. The suspension of the test microscopic organisms was included with NaCL 0.85% until it reaches turbidity, at that point a stick sterile cotton swab of bacterial suspension on the MHA (Muller Hinton Agar) media,  paper disks containing the antibiotics were put on the media and incubated for 24 hours. Results: Staphylococcus aureus, Enterobacter cloacae, Enterobacter aerogenes, Acinetobacter baumannii, Pseudomonas aeruginosa, Serratia odorifera, and Aeromonas hidropila were bacteria isolated from pus. S. aureus and E. cloacae were the most (25%).  Meropenen is the most sensitive antibiotics  (90%), Penicillin and Cefuroxime are the most resistance (45%). Conclusions : The resistance that happens at Vale Sorowako Inco Hospital is not due to a prescription without a culture test ask, since antibiotics given by clinicians are continuously based on a culture test, but since of the capacity of bacteria to produce b-lactamases and the the presence of genes that can code for b-lactamases which moreover cause bacteria to resistant to antibiotics.
Effectiveness of Black Cumin (Nigella sativa L.) Extract on Increasing Stamina in Male Mice (Mus musculus) Raina Aulia Melita; Delima Engga Maretha; Amin Nurokhman
Al-Kauniyah: Jurnal Biologi Vol 18, No 1 (2025): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v1i1.35311

Abstract

AbstractResearch using ethanol extract from black cumin seeds aims to find out whether black cumin seed extract (Nigella sativa) can be effective in increasing the stamina of male mice. The research design used was a completely randomized design (RAL). The samples used were 24 male mice consisting of four treatments and six repetitions. The dosing treatment consisted of a normal control group (P0), 30 mg/kg weight (P1), 60 mg/kg weight (P2), and 120 mg/kg weight (P3). The swimming test method was used to determine the effect of increasing stamina on mice. Data on the swimming duration of mice were analyzed using the ANOVA test then continued using the Post Hoc Test, namely LSD. The average stamina of mice based on swimming duration was the highest, namely at a dose of 120 mg/kgW (P3). Administration of black cumin seed extract (Nigella sativa) at doses of 30 mg/kgBW, 60 mg/kgW, and 120 mg/kgW for 14 days provided effectiveness in increasing stamina in male white mice (Mus musculus) as indicated by an increase in the swimming duration of the mice in each treatment.AbstrakPenelitian menggunakan ekstrak etanol biji jinten hitam bertujuan untuk mengetahui apakah ekstrak biji jinten hitam (Nigella sativa) dapat berpengaruh terhadap peningkatan stamina mencit jantan. Rancangan penelitian yang digunakan ialah rancangan acak lengkap (RAL). Sampel yang digunakan sebanyak 24 ekor mencit jantan yang terdiri dari empat perlakuan dan enam pengulangan. Perlakuan pemberian dosis terdiri atas kelompok kontrol normal (P0), 30 mg/kgBB (P1), 60 mg/kgBB (P2), dan 120 mg/kgBB (P3). Metode swimming test digunakan untuk mengetahui efek peningkatan stamina terhadap mencit. Data durasi renang mencit dianalisis menggunakan uji ANOVA kemudian dilanjutkan menggunakan uji Post Hoc Test yaitu LSD. Rata-rata stamina mencit berdasarkan durasi renang yang paling tinggi yaitu pada dosis 120 mg/kgBB (P3). Pemberian ekstrak biji jinten hitam (Nigella sativa) pada dosis 30 mg/kgBB, 60 mg/kgBB, dan 120 mg/kgBB selama 14 hari dapat berpengaruh dalam peningkatan stamina pada mencit putih jantan (Mus musculus) ditandai meningkatnya durasi renang mencit dimasing-masing perlakuan. 
Co-Authors Afriansyah, Dini Amin Nurokhman Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Ekafadly Jusuf Fifi Dismayanti Indriani Nainu Hafsan, Hafsan Ibrahim Ibrahim Indah Ayu puji rahayu Indah Ayu puji rahayu, Indah Ayu Irham Falahudin Irham Falahudin Irham Falahudin, Irham Joko Widodo Lianah Lianah, Lianah Mashuri Masri Mashuri Masri Mashuri Masri Mashuri Masri Mashuri Masri Muhammad Mustapha Adam Nur Wahid Nurhaida Widiani Putri Mareta Cahyani Raina Aulia Melita rika yera puspa Ruqoyyah Ruqoyyah Rusny Rusny Senja Senja Sisi Ananda Siska Tri Desianti Tri Ayu Tridesianti, Siska Usman Fajar Saputra Vina Prisunarti Putri Wahyuni Wahyuni Warobi Warobi