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All Journal AL KAUNIYAH Biogenesis: Jurnal Ilmiah Biologi Al Ilmi Biota Bio Ilmi: Jurnal Pendidikan Indonesian Journal of Biology Education Prosiding Seminar Nasional Biologi, Teknologi dan Kependidikan (Biotik) Conferences of Medical Sciences Dies Natalis
Delima Engga Maretha
Universitas Islam Negeri Raden Fatah Palembang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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THE ANTIBIOTIC RESISTANCE AND THE ABILITY OF BACTERIATO PRODUCE -LACTAMASES Mashuri Masri; Joko Widodo; Ekafadly Jusuf; Delima Engga Maretha; Wahyuni Wahyuni
Prosiding Seminar Nasional Biotik Vol 10, No 2 (2022): PROSIDING SEMINAR NASIONAL BIOTIK X 2022
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh, Aceh, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (714.435 KB) | DOI: 10.22373/pbio.v10i2.15165

Abstract

Background : Accessibility of bacterial patterns and their sensitivity to pus can be utilized as a thought in giving anti-microbials observationally. Vale Sorowako Inco Hospital was located in mining region where health services were not as enormous as in huge cities but can still carry out free sensitivity tests without send them to a referral hospital. Methods: Antibiotics (Penicillin, cefuroxime, Ceftriaxone, and meropenem) were tried by dise diffusion. The suspension of the test microscopic organisms was included with NaCL 0.85% until it reaches turbidity, at that point a stick sterile cotton swab of bacterial suspension on the MHA (Muller Hinton Agar) media,  paper disks containing the antibiotics were put on the media and incubated for 24 hours. Results: Staphylococcus aureus, Enterobacter cloacae, Enterobacter aerogenes, Acinetobacter baumannii, Pseudomonas aeruginosa, Serratia odorifera, and Aeromonas hidropila were bacteria isolated from pus. S. aureus and E. cloacae were the most (25%).  Meropenen is the most sensitive antibiotics  (90%), Penicillin and Cefuroxime are the most resistance (45%). Conclusions : The resistance that happens at Vale Sorowako Inco Hospital is not due to a prescription without a culture test ask, since antibiotics given by clinicians are continuously based on a culture test, but since of the capacity of bacteria to produce b-lactamases and the the presence of genes that can code for b-lactamases which moreover cause bacteria to resistant to antibiotics.
Effectiveness of Black Cumin (Nigella sativa L.) Extract on Increasing Stamina in Male Mice (Mus musculus) Raina Aulia Melita; Delima Engga Maretha; Amin Nurokhman
Al-Kauniyah: Jurnal Biologi Vol 18, No 1 (2025): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v1i1.35311

Abstract

AbstractResearch using ethanol extract from black cumin seeds aims to find out whether black cumin seed extract (Nigella sativa) can be effective in increasing the stamina of male mice. The research design used was a completely randomized design (RAL). The samples used were 24 male mice consisting of four treatments and six repetitions. The dosing treatment consisted of a normal control group (P0), 30 mg/kg weight (P1), 60 mg/kg weight (P2), and 120 mg/kg weight (P3). The swimming test method was used to determine the effect of increasing stamina on mice. Data on the swimming duration of mice were analyzed using the ANOVA test then continued using the Post Hoc Test, namely LSD. The average stamina of mice based on swimming duration was the highest, namely at a dose of 120 mg/kgW (P3). Administration of black cumin seed extract (Nigella sativa) at doses of 30 mg/kgBW, 60 mg/kgW, and 120 mg/kgW for 14 days provided effectiveness in increasing stamina in male white mice (Mus musculus) as indicated by an increase in the swimming duration of the mice in each treatment.AbstrakPenelitian menggunakan ekstrak etanol biji jinten hitam bertujuan untuk mengetahui apakah ekstrak biji jinten hitam (Nigella sativa) dapat berpengaruh terhadap peningkatan stamina mencit jantan. Rancangan penelitian yang digunakan ialah rancangan acak lengkap (RAL). Sampel yang digunakan sebanyak 24 ekor mencit jantan yang terdiri dari empat perlakuan dan enam pengulangan. Perlakuan pemberian dosis terdiri atas kelompok kontrol normal (P0), 30 mg/kgBB (P1), 60 mg/kgBB (P2), dan 120 mg/kgBB (P3). Metode swimming test digunakan untuk mengetahui efek peningkatan stamina terhadap mencit. Data durasi renang mencit dianalisis menggunakan uji ANOVA kemudian dilanjutkan menggunakan uji Post Hoc Test yaitu LSD. Rata-rata stamina mencit berdasarkan durasi renang yang paling tinggi yaitu pada dosis 120 mg/kgBB (P3). Pemberian ekstrak biji jinten hitam (Nigella sativa) pada dosis 30 mg/kgBB, 60 mg/kgBB, dan 120 mg/kgBB selama 14 hari dapat berpengaruh dalam peningkatan stamina pada mencit putih jantan (Mus musculus) ditandai meningkatnya durasi renang mencit dimasing-masing perlakuan. 
Co-Authors Afriansyah, Dini Amin Nurokhman Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Asnilawati Ekafadly Jusuf Fifi Dismayanti Indriani Nainu Hafsan Ibrahim Ibrahim Indah Ayu puji rahayu Indah Ayu puji rahayu, Indah Ayu Irham Falahudin Irham Falahudin Irham Falahudin, Irham Joko Widodo Lianah Lianah, Lianah Mashuri Masri Muhammad Mustapha Adam Nur Wahid Nurhaida Widiani Putri Mareta Cahyani Raina Aulia Melita rika yera puspa Ruqoyyah Ruqoyyah Rusny Rusny Senja Senja Sisi Ananda Siska Tri Desianti Tri Ayu Tridesianti, Siska Usman Fajar Saputra Vina Prisunarti Putri Wahyuni Wahyuni Warobi Warobi