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Diagnosis and Management of Adrenal Crisis in 46XX Congenital Adrenal Hyperplasia Infant Nur Rochmah; Muhammad Faizi; Neurinda Permata Kusumastuti; Leonardo Ferryanto Mak Samadhi; Wika Yuli Deakandi
Folia Medica Indonesiana Vol. 58 No. 3 (2022): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1436.417 KB) | DOI: 10.20473/fmi.v58i3.14891

Abstract

Highlight: The diagnosis and therapy of Congenital Adrenal Hyperplasia (CAH) children with Adrenal crisis (AC) case report. Adrenal crisis (AC) is a life-threatening emergency that contributes to the high death rate of children with adrenal insufficiency. The early detection and prompt treatment can improve the outcomes of patients with CAH and AC.   Abstract: Adrenal crisis is the acute complication of the patient with congenital adrenal hyperplasia. Congenital adrenal hyperplasia (CAH) is a rare condition. Children with CAH commonly come to the emergency room due to acute complications. The condition has high mortality and thus needs early recognition. Newborn screening for CAH in Indonesia is not routinely performed and has not been suggested yet. The purpose of this case report was to report a case of adrenal crisis in a congenital adrenal hyperplasia patient focused on diagnosis and therapy. A female, 10 months old infant, was admitted to the emergency department with a chief complaint of a decrease of consciousness for 3 hours before admission and frequent vomiting since born. On physical examination, there was clitoromegaly. Laboratory showed 17-OH progesterone: 173 ng/dL (7-77 ng/dL) and karyotyping: 46 XX. Management of adrenal crisis is a stress dose of hydrocortisone and rehydration. Education is the key to optimal outcomes and normal growth and development.
Psychological aspects of precocious puberty child during the COVID-19 pandemic Nurul Ima Suciwiyati; Nur Rochmah; Muhammad Faizi; Fadhil Abiyyu Yofi
Majalah Obstetri & Ginekologi Vol. 30 No. 3 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I32022.139-145

Abstract

HIGHLIGHTS 1. Presents a longitudinal case of a child with Organic Central Precocious Puberty (CPP).2. Focused on psychological aspect during the COVID-19 pandemic.   ABSTRACT Objective: To present a longitudinal case of a child with organic Central Precocious Puberty (CPP) that focused on medical, growth and development, and parent’s psychological aspect during the COVID-19 pandemic. Case Report: A 14-month old girl attended with major complaints of breasts enlargement and menstruation. The Tanner's stage was at A1M3P1 and the vagina showed reddish-brown spots. The patient’s bone age was advanced (3 years and 6 months). USG examination showed a corpus uterine: cervix ratio of 2:1. GnRH stimulation test showed an elevated of FSH/LH and estradiol. MRI showed an extra-axial dense mass that leads to Hypothalamic Hamartoma (HH). The definitive diagnosis of this patient was organic CPP with HH. The patient was managed with GnRH analog. Precocious puberty (PP) becomes a financial and psychosocial burden for parents. The COVID-19 pandemic adds a double burden for the parents. Conclusion: During the COVID-19 pandemic, parents with PP children had a good psychological aspect if the child was comprehensively handled with adequate motivation and psychoeducation.
EMPOWERMENT OF DIABETES MELLITUS PATIENT DURING COVID-19 PANDEMIC ERA THROUGH ONLINE GATHERING Nur Rochmah; Sukmawati Basuki; Fatimah Arief; Muhammad Faizi; Faisal Faisal; Juniastuti Juniastuti; Herman Kosasih
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 4 No. 2 (2022): OCTOBER 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpmk.v4i2.37884

Abstract

Introduction: In the COVID-19 pandemic, social restriction and lock-down policies were implemented. It has far-reaching implications in many sectors of life including health, particularly in patients with chronic diseases, one of which is Type-1 Diabetes Mellitus (T1DM). The purpose of this community service in the form of online gathering is to facilitate patients to ask questions and consult with pediatricians, due to the limitations of patients to consult directly due to the pandemic. Methods: Community service is conducted online for T1DM patients or their relatives on Sunday, September 26, 2021, from 12.00 - 13.30 WIB. The Community service was divided into several stages, including before, during, and after the online gathering.  The T1DM patients or their relatives are participants in this community services. The topic are types of Diabetes Mellitus, clinical presentation, disease progression, the diagnostic process, and its management therapy of type 1 diabetes mellitus. Results: The community service was attended by 54 parents of T1DM patient. The online gathering goes smoothly, without being constrained by something. During the online gathering, subjects actively participate in every session during the online gathering. Several questions were asked by the participants and answered well by the speakers. Conclusion: This community services activities allow participant to be able to ask question about their problem according to diabetes mellitus. Participants can consult online with pediatricians. This online gathering has a limited time, so participants can be divided into several breakout rooms with several accompanying pediatricians, so that the QnA session can be done optimally.
CLINICAL PROFILE OF TYPE-1 DIABETES PEDIATRIC PATIENTS IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL SURABAYA: CORRELATION OF GROWTH STATUS AND METABOLIC CONTROL Grawira Drana Putra Respati; Muhammad Faizi; Agung Pranoto; Mia Ratwita Andarsini
Majalah Biomorfologi Vol. 33 No. 1 (2023): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v33i1.2023.7-13

Abstract

Highlights1. Diabetes mellitus type 1 (DM) is a chronic autoimmune illness characterized by insulin insufficiency and hyperglycemia as a consequence.2. Stable HbA1c levels may be indicative of improved growth rates. AbstractBackground: Type-1 diabetes mellitus (DM) is a chronic auto-immune disease characterized by insulin insufficiency and resultant hyperglycemia caused by the destruction of insulin-producing beta cells in the pancreas. Metabolic control in type-1 DM affects the metabolism of patients, one of which is growth status, which is influenced by growth hormone. Improved growth rates can indicate stable HbA1c levels. However, whether growth is affected by the degree of diabetic control is still debatable. Objective: This study was conducted to determine whether the metabolic control correlates with growth status of children with type-1 diabetes in the Endocrine Polyclinic at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Material and Method: Retrospective observational analysis with a cross-sectional method was conducted on 96 type-1 DM patients at Dr. Soetomo General Academic Hospital Surabaya, Indonesia. The analysis was carried out using Chi-Square test to determine whether there was a correlation. Result: From a total of 96 pediatric patients, the majority was male (54.1%), patients with high-risk metabolic control were 79.2%, and those with z-score normal category were 62.5%. The results indicated no significant correlation between growth status and metabolic control of pediatric patients, with Chi-Square test results showed p=0.421 (p>0.05). Conclusion: There was no significant correlation between growth status and metabolic control of type-1 diabetes pediatric patients at the Endocrine Polyclinic Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Effect on Video Conference’s Education in Mandangin’s Community Health Center’s Healthcare Knowledge about Acute Diarrhea in Children Alpha Fardah Athiyyah; Andy Darma; Dwiyanti Puspitasari; Khadijah Rizky Sumitro; Ni Nyoman Metriani Nesa; Steven Christian Susianto; Muhammad Faizi; Reza Gunadi Ranuh; Subijanto Marto Sudarmo
Asian Journal of Health Research Vol. 2 No. 1 (2023): Volume 2 No 1 (April) 2023
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v2i1.61

Abstract

Introduction: The involvement and ability of health workers in Mandangin Island in early managing acute diarrhea in children to reduce infant mortality due to diarrhea are very important. This study aimed to determine the effect of community development Faculty of Medicine Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya in a seminar on Early Management of Acute Diarrhea in Children using video conference to educate health care workers (HCWs) at the Mandangin Community Health Center. Material and Methods: This cross-sectional study was designed on 20 HCWs at the Mandangin community health center. Subjects were evaluated for demographic data (gender, age, occupation, last education), and the knowledge was assessed using a pre-test before the seminar was given. We used questionnaire about acute diarrhea containing 10 questions with maximum score 100. The seminar was given through video conferences with form classical lecturer and a case study on acute diarrhea, and subjects attended the seminar in Community Health Center’s Hall. We assessed knowledge after the seminar using the same questionnaire with randomization in question and answer and compared the pre-and post-test using the Wilcoxon Rank sum test. Results: Most of the subjects were midwifery, with a mean age of 32.4 ± 5.75 years old, 45% with D-3 last education and 80% were female. There was a significant difference between pre-and post-test in acute diarrhea in children (47.89±20.7 vs 64.74±22.94) (p=0.008). Conclusion: Video conference education effectively increased health care workers' knowledge about acute diarrhea in children
Antibodies to Glutamic Acid Decarboxylase-65 is Associated with Total Daily Dose of Insulin Requirement in Children with Type 1 Diabetes Faisal Faisal; Nur Rochmah; Muhammad Faizi; Novina Novina; Erni Nuraeni
The Indonesian Biomedical Journal Vol 15, No 4 (2023)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v15i4.2377

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BACKGROUND: Type 1 diabetes (T1D) mostly occurs due to the destruction of pancreatic beta cells due to autoimmune processes. Diagnosis of T1D can be established by examining the c-peptide levels and the markers of pancreatic autoantibodies, including glutamic acid decarboxylase 65 autoantibodies (GAD-65). However, the association between c-peptide and anti-GAD-65 toward patients’ clinical manifestations needs to be further explored. Hence, the aim of current study was to identify the association of anti-GAD65 with c-peptide and clinical characteristics in children with T1D.METHODS: Case-control study involving 47 T1D children (T1D group) and 41 healthy children (control group) younger than 18 years old was conducted. Secondary data regarding subjects’ demographic characteristics and medical history were collected from subjects, and serum blood was drawn from each subject for the anti-GAD65 and c-peptide measurement. Anti-GAD65 and c-peptide levels were measured using an Enzyme-Linked Immunosorbent Assay (ELISA) methods.RESULTS: Anti-GAD65 antibody was detected in 78.7% T1D group, while only 2.43% were detected in control group subject (p=0.0000). The c-peptide level of T1D group was 0.07±0.19 nmol/L and control group was 1.5±0.77 nmol/L (p=0.0000). The total daily dose of insulin in subjects with positive anti-GAD65 was greater than in the negative anti-GAD65 (p=0.012). The sensitivity and specificity of the anti-GAD65 were 85.4% was 66.7%, respectively.CONCLUSION: The results of this study show that anti-GAD65 was associated with total daily dose of insulin requirement in children with T1D.KEYWORDS: diabetes mellitus, type 1 diabetes, anti-GAD65, c-peptide
UPAYA PENGUATAN PENGETAHUAN MASYARAKAT MENGENAI PENYAKIT GANGGUAN SALURAN CERNA FUNGSIONAL PADA ANAK DI PULAU MANDANGIN, KABUPATEN SAMPANG Subijanto Marto Sudarmo; Alpha Fardah Athiyyah; Andy Darma; Dwiyanti Puspitasari; Khadijah Rizky Sumitro; Ni Nyoman Metriani Nesa; Steven Christian Susianto; Muhammad Faizi; Reza Gunadi Ranuh
Jurnal Abdi Insani Vol 10 No 3 (2023): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v10i3.803

Abstract

Functional gastrointestinal disorders are problems that are often experienced by children, especially in isolated areas. Mandangin Island is among the secluded islands located in Sampang district.. The Department of Child Health, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital held a community development that aimed to increase public knowledge about functional gastrointestinal disorders in children on Mandangin Island, Sampang District. The community service was conducted using a hybrid seminar approach, where speakers participated remotely via Zoom while the local community gathered at the Village Hall on Mandangin Island.. The speakers explained the definition, important signs and symptoms, early management of Functional Gastrointestinal Disorders. All subjects who took part in community service activities were evaluated for knowledge based on pre- and post-tests, each of which consisted of 5 questions with maximum score 100. Subject’s knowledge was considered good if the score was ≥ 60. Based on our data, there were 29 people who participated in community development with the most working as fishermen and entrepreneurs. We found that 69% of the subjects had an increase in the pre-test score. At the time the pre-test was distributed, only 10.4% had good knowledge scores, while in the post-test there were 51.7% who had good knowledge. We also succeeded in making 3 health cadres caring in childhood functional gastrointestinal disorders. Community development in the form of health education for functional gastrointestinal disorders in children using video conference (ZOOM) on Mandangin Island could increase public knowledge and this activity can be implemented on other islands.