I Gusti Nyoman Darmaputra
Departemen Dermatologi Dan Venereologi, Fakultas Kedokteran Universitas Udayana/ RSUP Prof. Dr. I G. N. G. Ngoerah, Denpasar, Bali, Indonesia

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Journal : Journal of Global Pharma Technology

CLINICAL AND DERMOSCOPIC FEATURES OF SKIN CANCER AT SANGLAH GENERAL HOSPITAL, DENPASAR: A CASE SERIES STUDY Made Wardhana; Nila Puspasari; Prima Sanjiwani; Darmaputra Darmaputra
Journal of Global Pharma Technology Volume 09 Issue 04
Publisher : Journal of Global Pharma Technology

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Background: Dermoscopy or epiluminescence microscopy (ELM) is a non-invasive clinical examination technique of pigmented skin lesions and early stage skin cancers.Methods: This was a retrospective study of patients with skin cancer at dermatology outpatient clinic of Sanglah Hospital from January 2013 to December 2014. These patients were firstly assessed with unaided eye before underwent a dermoscopic examination. All diagnoses were confirmed with a histopathology examination.Results: There were 22 patients with skin cancer who enrolled in this study. The study participants were redominantly women (59.1%), age over 50 years (72.7%), working outdoor (90.9%), with the predominantly predominant site being on the face (96%). There were 7 patients (31.8%)  with malignant melanoma and the predominant dermoscopic features were: atypical pigment network (71.4%), blue whitish veil (57.1%) and irregular streaks (57.1%). There were 10 patients (45.5%) with basal cell carcinoma, with the predominant dermoscopic feature being the arborizing vessel (60%) and ulceration (70%). There were 5 squamous cell carcinoma patients (22.7%) and the predominant dermoscopic features observed were keratin (80%) and hairpin vessels (100%). The histopathological examination results were in accordance with the description of dermoscopy featuresConclusions: Dermoscopy is a non-invasive tool for diagnosis of early skin cancer prior to performing a biopsy for histopathologic examination.
A Retrospective Study of Erythema Nodosum Leprosum in Dermatology and Venereology Outpatient Clinic of Sanglah General Hospital, Bali-Indonesia I Gusti Nyoman Darmaputra
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

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Introduction: Erythema nodosum leprosum (ENL) or type II reaction in leprosy is acute inflammation in the chronic disease of multibacillary leprosy. Clinical manifestation of ENL on the skin such as painful cutaneous nodule, commonly found on the face and extremities accompanied by nerve inflammation, systemic involvement, and other extracutaneous symptoms which possibly caused disability if it is not treated appropriately. Aim: To find out the ENL pattern in the Department of Skin and Venereology, Sanglah General Hospital for three years. Methods: This study was a retrospective study from the medical record of ENL new cases treated in the Skin and Venereology Outpatient Clinic, within period January 2013-December 2015 classified by the number of patients, age, sex, and type of leprosy. Result: Starting from January 2013-December 2015 there were about 39 new leprosy patients with ENL (36% of all new patients in the leprosy division), 64% are male, 82% aged 17-45 years, and 69% of patients suffer from borderline lepromatous (BL) leprosy. Conclusion: Most leprosy patients with ENL are male, aged 17-45 years with BL type leprosy. Complications that arise due to ENL or the side effects of corticosteroids could cause a large socio-economic impact.Keywords: Erythema nodosum leprosum, Leprosy reaction, Sanglah General Hospital.