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All Journal journal of internal medicine Jurnal Berkala Epidemiologi Indonesian Journal of Tropical and Infectious Disease Syntax Literate: Jurnal Ilmiah Indonesia Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Mitra Raflesia (Journal of Health Science) Narra J
Bramantono Bramantono, Bramantono
Department Of Internal Medicine, Faculty Of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital Surabaya, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Association between chest X-ray score and clinical outcome in COVID-19 patients: A study on modified radiographic assessment of lung edema score (mRALE) in Indonesia Rahayu, Dwi RP.; Rusli, Musofa; Bramantono, Bramantono; Widyoningroem, Anita
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.691

Abstract

Radiological examinations such as chest X-rays (CXR) play a crucial role in the early diagnosis and determining disease severity in coronavirus disease 2019 (COVID-19). Various CXR scoring systems have been developed to quantitively assess lung abnormalities in COVID-19 patients, including CXR modified radiographic assessment of lung edema (mRALE). The aim of this study was to determine the relationship between mRALE scores and clinical outcome (mortality), as well as to identify the correlation between mRALE score and the severity of hypoxia (PaO2/FiO2 ratio). A retrospective cohort study was conducted among hospitalized COVID-19 patients at Dr. Soetomo General Academic Hospital Surabaya, Indonesia, from February to April 2022. All CXR data at initial admission were scored using the mRALE scoring system, and the clinical outcomes at the end of hospitalization were recorded. Of the total 178 COVID-19 patients, 62.9% survived after completing the treatment. Patients within non-survived had significantly higher quick sequential organ failure assessment (qSOFA) score (p<0.001), lower PaO2/FiO2 ratio (p=0.004), and higher blood urea nitrogen (p<0.001), serum creatinine (p<0.008) and serum glutamic oxaloacetic transaminase (p=0.001) levels. There was a significant relationship between mRALE score and clinical outcome (survived vs deceased) (p=0.024; contingency coefficient of 0.184); and mRALE score of ≥2.5 served as a risk factor for mortality among COVID-19 patients (relative risk of 1.624). There was a significant negative correlation between the mRALE score and PaO2/FiO2 ratio based on the Spearman correlation test (r=-0.346; p<0.001). The findings highlight that the initial mRALE score may serve as an independent predictor of mortality among hospitalized COVID-19 patients as well as proves its potential prognostic role in the management of COVID-19.
Comorbid Factors and Duration of Illness in Dengue Hemorrhagic Fever Patients at Universitas Airlangga Hospital, Surabaya, Indonesia Savita, Lady; Sulistiawati; Bramantono; Maimunah, Ummi
Journal of Community Medicine and Public Health Research Vol. 5 No. 1 (2024): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v5i1.52966

Abstract

Dengue hemorrhagic fever (DHF) continues to prevail in Indonesia annually. Individuals afflicted with dengue hemorrhagic fever may exhibit distinct clinical manifestations, and these can vary based on individual factors. Numerous elements can contribute to this diversity. Typically, adult patients with comorbidities face a less favorable prognosis for the primary disease. This study aimed to examine the impact of comorbid factors on the severity of DHF, as well as its duration. The comorbidities considered in this research encompassed hypertension, diabetes mellitus, and obesity. This research employed an analytical approach and was conducted at Universitas Airlangga Hospital from January to December 2022. Medical records served as the primary data source for this study. A total of 121 patient samples were collected based on specific criteria. The criteria included adults (>18 years) treated at Universitas Airlangga Hospital, who had no comorbid diseases other than those under study, and possessed complete medical record data. The sampling technique employed in this research was total sampling, which adhered to the inclusion and exclusion criteria. This research demonstrated that comorbid factors were not associated with the severity of DHF (p<0.05), while the duration of illness in DHF patients was correlated with the severity of the disease (p=0.027).
Fungemia in Tertiary Hospitals; An Overview Fungal Profile, Antifungal Resistance, and Antifungal Therapy Monita, Syafira Putri; Endraswari , Pepy Dwi; Bramantono; Asmarawati , Tri Pudy; Khanfar, Sarah Amjad Abdel-Raouf
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 1 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i1.66500

Abstract

Fungemia is a bloodstream infection caused by fungal pathogen and commonly occurs in hospitalized patients with certain risk factors. Indonesia itself is a tropical country with middle income that makes the incidence rate of fungemia tend to be higher, namely10/1 0,000 people. A recent study about candidemia conducted in Dr. Soetomo General Academic Hospital stated that the most common species that caused candidemia is Candida albicans (33.96%) and the blood sample mostly collected from patients from high care unit and patient with diabetes. We conducted this study to provide a new overview of data on the profile of the causes of fungal infections, patterns of fungal resistance to antifungals, and antifungal therapy in patients with fungemia in hospitalized patients at Dr. Soetomo General Academic Hospital, Surabaya, for the period of January December 2023. This research is a descriptive study using the patient’s medical records. Variables observed in this study include; gender, age, care unit, risk factor, species distribution, resistance pattern, type of antifungal therapy, and duration of antifungal therapy. Mostly the blood cultures are collected from female patients aged 0-9 years old. This study also found that most blood cultures are collected from patients in intensive care unit with use of CVC. Most of the patients did not receive antifungal therapy The most frequent found species is Candida parapsilosis with highest resistance rate found in Amphotericin-B. The most common antifungal that is used is Fluconazole which is mostly given within the range of 8-14 days .
Profile of Patients with Viral Infection at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2016-2018 Putri, Melati Adinda; Astari, Linda; Bramantono, Bramantono; Anggraeni, Sylvia
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.122-128

Abstract

Highlights: The most common viral skin infections at the Dermatology and Venerology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2016-2018 were shingles, verruca vulgaris, varicella, molluscum contagiosum, and measles. Viral skin infections predominantly affected late teens (17-25 years old), females, and each disease presented different clinical manifestations and treatments.   Abstract Introduction: The high incidence of viral skin infections in Indonesia, combined with a lack of understanding of risk factors and prevention measures, poses a significant problem. Few studies have examined the epidemiological profile of viral skin infections in Indonesia. This study aimed to evaluate the profile of patients with viral infections at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2016 to 2018. Methods: This was a descriptive, retrospective study based on the medical records of 560 patients collected between January 2016 and December 2018 (n=560). All data calculations were performed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26. Results: The prevalence of the five viral infections was 71.8% among all patients with viral infections. The most common diagnosis was shingles (47.5%), the most affected age group was late teens (17-25 years old) (21.3%), the most common gender was female (52,9%), the most frequent clinical manifestation was vesicles (52.1%), and the most commonly used therapy type was topical (73.4%). Conclusion: The number of patients with viral infections at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, has increased annually, requiring more comprehensive management to reduce morbidity and mortality.
Pola Kuman Serta Kepekaan Antibiotik pada Pasien Sepsis di Ruang Rawat Inap Penyakit Dalam RSUD dr. Soetomo Surabaya Nabila, Nabila; Bramantono, Bramantono; Kusumaningrum, Deby; Widodo, Agung Dwi Wahyu
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i8.17294

Abstract

Sepsis adalah disfungsi organ yang mengancam jiwa yang disebabkan oleh disregulasi respon host terhadap infeksi. Penatalaksanaan sepsis salah satunya adalah pemberian antibiotik spesifik, namun pengobatan awal adalah pemberian antibiotik spektrum luas sebelum ada hasil kultur. Penggunaan antibiotik yang tidak tepat pada pasien septik dapat menyebabkan resistensi bakteri dan memperburuk kondisi pasien. Tujuan penelitian ini adalah mempelajari pola sensitivitas bakteri dan antibiotik pada pasien sepsis di RSUD Dr. Soetomo Surabaya Metode. Penelitian deskriptif retrospektif ini dilakukan di RSUD Dr. Soetomo pada bulan Januari sampai dengan Desember 2019. Sampel penelitian ini adalah seluruh data rekam medis pasien sepsis yang memiliki hasil kultur darah bakteri positif di Laboratorium Mikrobiologi Klinik RSUD Dr. Soetomo Surabaya di Hasil 2019. Hasil penelitian menunjukkan bahwa dari 722 sampel darah, termasuk 124 (17,2%) sampel dengan hasil kultur positif. Pasien termuda berusia 16 tahun dan tertua berusia 97 tahun. Hasil ini juga menunjukkan bahwa sebagian besar pasien sepsis adalah perempuan. Bakteri yang paling banyak ditemukan adalah Staphylococcus spp. 80,4%. Bakteri gram positif (Staphylococcus spp.) sensitif terhadap linezolid, vankomisin, teicoplanin Kesimpulan. Bakteri yang paling banyak ditemukan adalah Staphylococcus spp, sedangkan antibiotik yang paling sensitif terhadap Staphylococcu spp gram positif adalah antibiotik linezolid, vankomisin, dan teicoplanin.
Co-Authors Agung Dwi Wahyu Widodo Agustinus Vincent Anggraeni, Sylvia Arfianto V Asmarawati, Tri Pudy Brian Eka Rahman Danny Irawan Deby Kusumaningrum Dedy Hadi Prawono Erika Marfiani Erwin Astha Triyono Hadi U Hamidah - Hasan, Helmia Khanfar, Sarah Amjad Abdel-Raouf Kuntaman Kuntaman Linda Astari, Linda M Vitanata Monita, Syafira Putri Muhammad Vitanata Arfijanto, Muhammad Vitanata Muhammad Vitanata Arifijanto Muhammad Vitanata Arifijanto Musofa Rusli Nabila, Nabila Nasronudin Nasronudin Nenci Siagian Neneng Dewi Kurniati Pepy Dwi Endraswari, Pepy Dwi Pius Sebastian Ginting Pranaya, Azhraa Qinan Prihartini Widiyanti Purwati - Putri, Melati Adinda Rachman, Brian Eka Rahayu, Dwi RP. Ramadhani, Pristya Resti Yudhawati Rosantia Sarassari Rusli, Musofa Sacharissa Zerlina Tsarwah Thirafi Savita, Lady Sedana, Made Putra Siti Irma Mashitah, Siti Irma Soewandojo E Suharto - Sulistiawati Tripudi Asmarawati Triyono EA Tuksin Jearanaiwitayakul Ummi Maimunah Usman Hadi Usman Hadi Widyoningroem, Anita