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All Journal Journal of Nutrition College Majalah Kedokteran Bandung e-Journal Pustaka Kesehatan Althea Medical Journal Indonesian Journal of Urology Journal of Agromedicine and Medical Sciences SRIWIJAYA JOURNAL OF MEDICINE Journal of Health Sciences Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Kesmas Untika Luwuk: Public Health Journal Jurnal Pengabdian Pada Masyarakat Indonesia (JPPMI) Jurnal Teknologi Sumberdaya Mineral
Zahrah Febianti
Biochemistry Department, Faculty Of Medicine, University Of Jember
Dentistry Earth & Planetary Sciences Energy Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : e-Journal Pustaka Kesehatan

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Pengaruh Pemberian Ekstrak Tauge Kacang Hijau (Vigna Radiata (L.)) terhadap Ketebalan Tunika Intima-Media Aorta Abdominalis pada Tikus Wistar Jantan yang diberi Stres Fisik (The Effect of Mung Bean (Vigna radiata (L.)) Sprout Extract on Tunica Intima-Me Galuh Dharanindya Ica Manohara; Rena Normasari; Zahrah Febianti
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Mung bean (Vigna radiata (L.)) sprout contains antioxidants especially vitamin E that can prevent oxidative stress and maintain cell membranes from lipid peroxidation, so the development of atherosclerosis can be inhibited. This study investigated the effect of mung bean sprout on the aorta abdominalis tunica intima-media thickness of male wistar rats induced by physical stress. It was a true experimental study with Post-test Only Control Group Design. Twenty five male wistar rats aged 2-3 months, divided into 5 groups: K1, K2, P1, P2 and P3. K1 was a normal group without treatment. The other groups were given physical stress such as swimming test for ten days. P1, P2, and P3 group were treated by 25, 50, and 100 mg/200g/day of mung bean sprout extract simultaneously. At the end of treatment, the aorta abdominalis were taken and prepared for histopathology examination. The result showed the average of tunica intima-media thickness in K1 30,25±1,65 µm; K2 32,45±5,02 µm; P1 31,65±2,63 μm; P2 30,35±4,73 μm and P3 30,45±3,21 μm. Data analysis using One Way ANOVA showed a significancy of p=0,839. In conclusion, there was no effect of the mung bean sprout extract on tunica intima-media thickness of male wistar rats induced by physical stress.   Keywords: Mung bean, physical stress, tunica intima-media
Uji Toksisitas Akut Ekstrak Buah Bruguiera gymnorrhiza pada Tikus (Rattus norvegicus) (Acute Toxicity Test of Bruguiera gymnorrhiza Fruit Extract In Rats (Rattus norvegicus)) Salman Al Farisi; Al Munawir; Zahrah Febianti
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Bruguiera gymnorrhiza (bakau) fruit has a great potency as a traditional medicine, but the safety has not known yet, therefore a test to determine the toxic effects of this fruit into living thing is needed. This research aimed to determine the acute toxicity effect of Bruguiera gymnorrhiza fruit extracts in rats based on Loomis criteria. This research was an experimental research laboratory with Post Test Only Control Group Design. Ten rats were divided into two groups. The control group was fed with a standard food while the treatment group was given Bruguiera gymnorrhiza (bakau) fruit extract at a dose of 5.000 mg/kg BB. After 24 hours, two groups were observed by calculating the number of the dead rats, if there was no dead rat, they were sacrificed for an autopsy for liver histopathological examination. The result of this research showed there was no dead rat during the treatment process . Histopathological examination of rat liver cells showed no necrosis, degeneration, inflammation, fibrosis, and cirrhosis. Conclusion of this research was Bruguiera gymnorrhiza (bakau) fruit had no toxic effects and could be clasified as “Practical Not Toxic” in Loomis criteria .   Keywords: Bruguierra gymnorrhiza (bakau) fruit , the acute toxicity effect, rat
Co-Authors Adellia Fira Fa'idha Al Munawir Azham Purwandhono Bagus Hermansyah Cholis Abrori, Cholis Danang Tejamukti Widiatmaja Diana Chusna Mufida Elly Nurus Sakinah, Elly Nurus Erfan Efendi Fanteri Aji Dharma Suparno Galuh Dharanindya Ica Manohara Hairrudin Hairrudin Handoko, Adelia Ika Rahmawati Sutejo Ivan Iqbal Baidowi Jauhani, Muhammad Afiful Jauhar Firdaus Kristianningrum Dian Sofiana Kusumastuti, Inke M. Ihwan Narwanto Mauliya Sri Sukmawati Wahyudi Muhammad Rijal Fahrudin Hidayat Nindya Shinta Rumastika Nurfahimi, Yudriani Putri, Elvia Rahmi Marga Radiva Eryadana, Aqshal Rayyan, Muhammad Isra Rafidin Rena Normasari Salman Al Farisi septa surya wahyudi, septa surya Septyawati, Ratna Sugiyanta Sugiyanta Syahda Nabilla Aristawidya Utama, Bagas Wahyu Widiatmaja, Danang Tejamukti Yudha Nurdian Yunita Armiyanti