Article Per Year (5 Year)
p-Index From 2021 - 2026
2.957
P-Index
This Author published in this journals
All Journal Bulletin of Chemical Reaction Engineering & Catalysis CHEMPUBLISH JOURNAL UNEJ e-Proceeding JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya ALCHEMY Jurnal Penelitian Kimia JMM (Jurnal Masyarakat Mandiri) Warta Pengabdian Jurnal Teknologi Jurnal Pengabdian Kepada Masyarakat MEMBANGUN NEGERI Journal of Biobased Chemicals (JOBC) Bulletin of Chemical Reaction Engineering & Catalysis Indonesian Journal of Science and Education
Helda Wika Amini
Prodi Teknik Kimia, Universitas Jember
Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Electrical & Electronics Engineering Energy Engineering Environmental Science Materials Science & Nanotechnology Physics Social Sciences Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Optimasi Ekstraksi Flavonoid dari Ulva lactuca dengan Kombinasi Cell Disruption dan Ultrasound-Assisted Hot Water Helda Wika Amini; Muhammad Rizky Kurniawan; Nida Ayu Salsabila; Boy Arief Fachri; Zuhriah Mumtazah; Meta Fitri Rizkiana; Istiqomah Rahmawati; Bekti Palupi; Yukti Nurani; Rekfa Wika Amini
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 2 (2025): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.2.98141.284-295

Abstract

Ulva lactuca merupakan biota laut yang berpotensi sebagai sumber bahan aktif kosmetik karena kandungan bioaktifnya seperti flavonoid, alkaloid, saponin, terpenoid, dan tanin. Penelitian ini bertujuan mengekstraksi flavonoid serta menganalisis nilai Sun Protection Factor (SPF) U. lactuca menggunakan kombinasi metode cell disruption dan ultrasound-assisted hot water (UAHW). Tiga metode perlakuan cell disruption (tanpa perlakuan, osmotic shock, dan hidrotermal dengan autoklaf) dikombinasikan dengan variabel UAHW yaitu suhu ultrasonik (40, 60, 80 °C) dan waktu ultrasonik (5, 10, 15 menit). Ekstraksi dilakukan menggunakan pelarut etanol 96% pada serbuk U. lactuca berukuran 60 mesh. Optimasi dilakukan menggunakan Response Surface Methodology (RSM) dengan Box–Behnken Design (BBD). Hasil menunjukkan bahwa total flavonoid dan nilai SPF tertinggi (33,23 mg QE/g dan SPF 20,80) diperoleh tanpa perlakuan cell disruption, pada suhu 80 °C dan waktu ekstraksi 10 menit. Penelitian ini menegaskan bahwa metode UAHW efektif meningkatkan ekstraksi flavonoid dan SPF meskipun tanpa cell disruption. Selain itu, pendekatan RSM terbukti efisien dalam optimasi proses. Studi ini memberikan kontribusi pada pengembangan bahan aktif alami U. lactuca untuk aplikasi kosmetik, khususnya sebagai agen pelindung sinar UV.Optimization of Flavonoid Extraction from Ulva lactuca Using a Combination of Cell Disruption and Ultrasound-Assisted Hot Water. Ulva lactuca is a marine organism with significant potential as a source of active ingredients for cosmetic applications, owing to bioactive compounds such as flavonoids, alkaloids, saponins, terpenoids, and tannins. This study aimed to extract flavonoids and evaluate the Sun Protection Factor (SPF) of U. lactuca using a combination of cell disruption methods and ultrasound-assisted hot water (UAHW) extraction. Three cell disruption treatments (no treatment, osmotic shock, and hydrothermal using an autoclave) were combined with UAHW variables, including ultrasonic temperature (40, 60, 80 °C) and ultrasonic time (5, 10, 15 minutes). The extraction was conducted using 96% ethanol as a solvent on U. lactuca powder sieved to 60 mesh. Optimization was performed using Response Surface Methodology (RSM) with a Box–Behnken Design (BBD). The highest total flavonoid content (33.23 mg QE/g extract) and SPF value (20.80) were obtained without cell disruption, at 80°C for 10 minutes. The study confirms that UAHW effectively enhances flavonoid extraction and SPF, even without cell disruption. Furthermore, the RSM approach proved efficient for process optimization. This study contributes to developing natural active ingredients from U. lactuca for cosmetic applications, particularly as UV-protective agents.
Co-Authors Afidatul Muadifah Afred, Merymistika Yufrani Alfinaini, Nur Aini Dwi Alfinaini Ansori Ansori Ari Susanti Atiqa Rahmawati Bekti Palupi Bimo Bayu Aji Boy Arief Fachri Boy Fachri Dini Rahmawaty Ditta Kharisma Yolanda Putri Dyah Ayu Savitri Fakhri Arkaan Humaidi Faqih, Hana Felix Arie Setiawan Fitriah Novita Sari Ghina Shofiah Adibah Khoirunnisa Gregah Pangayoman Hartanto P Hanggara Sudrajat Hanggara Sudrajat Husnatun Nihayah Indra Lasmana Tarigan Istiqomah Rahmawati Istiqomah Rahmawati Julieta, Theressa Lailatul Fatma Meta Fitri Rizkiana MIFTAKHUL ULUM Mizanurafi’ Ghifarhadi Prasiefa Muhammad Reza Muhammad Rizky Kurniawan Muharja, Maktum Nabilah Lu’aili Fauziah Nida Ayu Salsabila Nikita Meidi Nurtsulutsiyah Nurtsulutsiyah Nurul Ulya Luthfiyana Pratamai Shelli Ratri Sekaringgalih Raygita May Hastuti Rekfa Wika Amini Rizki Fitria Darmayanti Rizki Fitria Darmayanti Rizky Pratama, Reinaldi Sonya Hakim Raharjo Susilowati Syarifah, Ratna Dewi Tri Kurnia Astutik Wiwik Pratiwi Yakub Hendrikson Manurung Yukti Nurani Yukti Nurani Zuhriah Mumtazah