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All Journal Medical Journal of Indonesia Majalah Patologi Indonesia Jurnal Respirasi (JR) JURNAL ETIKA KEDOKTERAN INDONESIA Indonesian Journal of Medical Chemistry and Bioinformatics
Irandi Putra Pratomo
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine/Pulmonology And Respiratory Medicine Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia/Bioinformatics Core Facilities, Indonesian Medical Educa
Chemistry Computer Science & IT Health Professions Medicine & Pharmacology Public Health

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Journal : Jurnal Respirasi (JR)

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Preparation and Findings in Diagnostic and Therapeutic Flexible Fiberoptic Bronchoscopy Procedures in Patients with COVID-19 Irandi Putra Pratomo; Hario Baskoro; Dicky Soehardiman; Prasenohadi Prasenohadi; Tutug Kinasih; Ahmad Fauzi; Ike Maretta; Nachita Putri; Kentaro Tokumo
Jurnal Respirasi Vol. 9 No. 1 (2023): January 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.1.2023.72-79

Abstract

The coronavirus disease 2019 (COVID-19), which has raised concerns about infection control for every clinical procedure, including flexible fiberoptic bronchoscopy (FFB), has drawn the attention of clinicians across the globe. A pulmonologist frequently conducts this procedure to diagnose and treat pulmonary diseases like COVID-19. This procedure involves direct airway observation and generates aerosol from the patient. However, it is considered a double-edged sword, as the risk of infection and instrument contamination always haunts its clinical benefit to the patients and the operators. Therefore, a guideline for preparing and indicating FFB in COVID-19 must be addressed appropriately by emphasizing the importance of infection prevention and control. Fortunately, several recommendations and findings have emerged over the past three years, which should support safe FFB procedures for its operators with controlled infection. This study summarizes the indication, objective, contraindication, risk, preparation, and findings in diagnostic and therapeutic FFB patients with COVID-19.
The Role of Genome-Wide Association Study in Pulmonary Disease Diagnostics: A Review in Medical Bioinformatics Andromeda, Rossalyn; Pratomo, Irandi Putra; Fauzi, Ahmad; Kinasih, Tutug; Prasenohadi, Prasenohadi; Santoso, Arif; Tokumo, Kentaro
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.76-84

Abstract

Biomedical science, which initially required only conventional research in the laboratory, currently involves information technology and has created bioinformatics in its development. Bioinformatics, a branch of biology, quantitatively analyzes information within biological macromolecules using software. Contemporary applications of bioinformatics have advanced biotechnological, medical, and pharmaceutical practices. Among the established applications of bioinformatics is diagnosing lung diseases using the genome-wide association study (GWAS) technique. Owing to sequencing technology and rapid computational methods, this technique is applied to analyze the link between genes with essential traits in the population, thus mapping the target genes to diagnose and treat diseases. The lung diseases diagnosed using GWAS include the responsible locus in asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. Moreover, it can identify the treatment for COPD and suggest a new locus in lung cancer. Advancing the current gene-mapping technology demands genotype and phenotype data to study disease-linked genomes. Currently, bioinformatics is barely known and receives little attention in Indonesia. However, it can grow rapidly through open-source basis data and cross-disciplinary collaboration.
Co-Authors Ahmad Fauzi Andromeda, Rossalyn Arif Santoso Aris Ramdhani Aryo Tedjo Dimas Ramadhian N Dwi Anita Suryandari Fauzi Ahmad Muda Gatut Priyonugroho Hadi Sunaryo Hario Baskoro Ike Maretta Indra Fahri Ira Siagian Irwin Tedja Ivan R. Widjaja Jowy Tani Kentaro Tokumo Khaerunissa Anbar Istiadi Kinasih, Tutug Kusmardi Kusmardi Luluk Yunaini Nachita Putri Prasenohadi Prasenohadi Prasenohadi, Prasenohadi Ratna Suryani Gandana Saptawati Bardosono Soehardiman, Dicky Tokumo, Kentaro Tutug Kinasih Zarni Amri