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GAMBARAN KLINIKOPATOLOGI POLIP HIDUNG DI POLIKLINIK  THT-KL RSUP DR. M. DJAMIL TAHUN 2019-2021 Dira, Atshyfa Zsazsa; Huriyati, Effy; Rustam, Erlina; Djosan, Al Hafiz; Endrinaldi, Endrinaldi; Intan, Shinta Ayu
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1257

Abstract

Nasal polyps appear as a round, semi-transparent mass and typically develop in the middle meatus and paranasal sinuses. Histologically, nasal polyps can be divided into two subtypes, eosinophilic and neutrophilic polyps. The recurrence rate of nasal polyps is quite high, with 60-70% of patients experiencing recurrence after undergoing FESS treatment for about 18 months. The purpose of this study was to determine the clinical and histopathological characteristics of patients with nasal polyps at the THT-KL Polyclinic of Dr. M. Djamil Central Hospital in 2019-2021. This study used a descriptive design with total sampling method. The sample in this study consisted of 77 patients who met the inclusion criteria. The results of this study showed that the most frequent clinicopathological characteristics of nasal polyps in the patients were: middle-aged age group (37.66%), male gender (54.5%), sinusitis risk factor (89.61%), bilateral nature of polyps (57.14%), the most common stage was stage II (50.65%), clinical symptom of nasal congestion (98.7%), surgical management (88.31%), neutrophilic histopathological type (84.42%), with a recurrence rate of 19.48%. In conclusion, the most frequent age distribution of patients with nasal polyps was in the 41-60 age group, with the most common male gender, sinusitis risk factor, bilateral type of polyps, the most common stage was stage II, clinical symptom of nasal congestion, the most common management was surgical, histopathological type was neutrophilic, and is recurrent
HUBUNGAN STATUS IMUNISASI BCG DENGAN MORTALITAS DAN DERAJAT SEVERITAS MENINGITIS TUBERKULOSIS ANAK DI RSUP DR. M. DJAMIL PADANG PERIODE 2018 – 2021 Nixon, Poety Elberta Husna; Lestari, Rahmi; Intan, Shinta Ayu; Amelin, Fitrisia; Ermayanti, Sabrina; Adrial, Adrial
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 6 (2025): SINERGI : Jurnal Riset Ilmiah, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i6.1314

Abstract

Objective: This study aims to determine the relationship between BCG immunization status with mortality and severity of TB meningitis in children at RSUP Dr. M. Djamil Padang. Method: This study used a cross-sectional design in children with TB meningitis and used the Kolmogorov-Smirnov and Chi-Square statistical tests. Sampling using total sampling technique with a total sample of 58 people. Data obtained from the medical records of RSUP Dr. M. Djamil Padang in 2018 – 2021. Result: This study shows that most pediatric TB meningitis patients with the condition are women (53%), aged 0-4 years (48%), good nutritional status (40%), not in direct contact with TB patients (74%), received BCG immunization (55%), severe degree (59%), and alive (76%). There is a relationship between BCG immunization status and degree of severity (p=0.046) and mortality (p=0.047) of pediatric TB meningitis patients at RSUP Dr. M. Djamil Padang in 2018 – 2021. Conclusion: The conclusion of this study is that there is a relationship between BCG immunization status and the degree of severity and mortality of TB meningitis in children at RSUP Dr. M. Djamil Padang in 2018 – 2021.
Fine Needle Aspiration Biopsy as A Useful Diagnostic Adjunct in The Management of Ameloblastoma: A Cytology Case Report Rum Affida Rasfa; Shinta Ayu Intan; Noza Hilbertina; Meta Zulyati Oktora
Scientific Journal Vol. 4 No. 4 (2025): SCIENA Volume IV No 4, July 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v4i4.249

Abstract

Background: Ameloblastoma is one of the most common benign odontogenic tumors, known for its slow growth but locally invasive behavior, often leading to extensive bone destruction if not diagnosed and treated early. Preoperative diagnosis of ameloblastoma can be made by Fine Needle Aspiration Biopsy (FNAB) which is used as a guide for surgical planning. Diagnosis of ameloblastoma from cytology is challenging due to many pitfalls and differential diagnosis with other odontogenic lesions, but proper sampling and accurate diagnosis are very useful inpatient management Understanding its cytomorphological features can greatly assist in early differentiation from other maxillofacial neoplasms. This case report aims to describe the appearance of ameloblastoma on FNAB and reveal the contribution of the FNAB examination in the preoperative diagnosis of ameloblastoma so that adequate surgery can be carried out and the results are more optimal. Case report: We report a case of a tumor in the mandible of a 16-year-old man with a diagnosis of right mandibular tumor. The patient was sent for FNAB to the anatomical pathology laboratory. Preoperative cytology examination showed benign odontogenic lesions indicating ameloblastoma from FNAB. Furthermore, tumor resection was performed on the patient and histopathology tissue examination was performed with results consistent with ameloblastoma. Discussion: The FNAB procedure can be performed to establish for a pre-operative diagnosis of ameloblastoma. Cytological characteristics of ameloblastoma include basaloid cells or epithelial cells resembling ameloblasts with nuclei arranged palisade at the periphery and in the middle consisting of cells resembling stellate reticulum cells. False-negative results in the FNAB procedure can occur due to inadequate specimens or inaccurate sampling, mostly related to cystic tumors. To avoid this, FNAB tissue sampling can be performed at multiple sites and the deeper aspects of the tumor can assist in establishing an accurate preoperative diagnosis. Conclusion: The FNAB cytology is a reliable procedure for the pre-operative diagnosis of ameloblastoma. Pre-operative diagnosis of ameloblastoma can be used for planning therapy and early diagnosis of recurrence cases that can improve patient survival. The correlation between t
Evaluasi Penggunaan Obat Antiemetik pada Pasien Kanker Ovarium Pasca Kemoterapi Putra, Xavier Novdi Tansyah; Rustam, Erlina; Ariani, Novita; Rahmatini; Muhammad, Syamel; Intan, Shinta Ayu
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 4 (2025): Desember 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i4.1362

Abstract

Latar Belakang: Kanker ovarium merupakan kanker pada perempuan yang cukup sering terjadi dan mematikan. Penggunaan kemoterapi dalam pengobatan dapat menyebabkan mual muntah sehingga diperlukan penggunaan obat yang efektif dan rasional. Objektif: Untuk mengevaluasi penggunaan obat antiemetik pada pasien kanker ovarium pasca kemoterapi di RSUP Dr. M. Djamil Padang tahun 2020-2022. Metode: Penelitian ini merupakan penelitian deskriptif dengan pendekatan retrospektif. Data rekam medis dikumpulkan dengan teknik total sampling. Sampel yang memenuhi inklusi berjumlah 45 sampel. Hasil: Hasil penelitia­­n didapatkan karakteristik terbanyak pada kelompok usia 41-60 tahun (48,9%), berpendidikan SLTU (75,6%), dan pekerjaan ibu rumah tangga (55,6%). Jenis obat kemoterapi yang paling banyak digunakan adalah paklitaksel-karboplatin (42,2%). Sebagian besar pasien mendapatkan antiemetik pra-kemoterapi berupa deksametason-difenhidramin-ondansetron-ranitidin (71,1%) serta pasca kemoterapi berupa metoklopramid-ranitidin dalam 3 siklus (74,8%). Rasionalitas penggunaan obat antiemetik pada pasien kanker ovarium pasca kemoterapi yaitu kesesuaian indikasi 93,3%, kesesuaian obat 62,2%, kesesuaian dosis 91,1%, kesesuaian pasien 97,8% dan potensi interaksi obat 2,2%. Kesimpulan: Karakteristik pasien kanker ovarium di RSUP Dr. M. Djamil Padang tahun 2020-2022 sering terjadi pada kelompok usia 40-60 tahun, pendidikan SLTU, dan pekerjaan ibu rumah tangga. Sebagian besar pasien mendapatkan obat kemoterapi paklitaksel-karboplatin dan obat antiemetik pra-kemoterapi deksametason-domperidon-ondansetron-ranitidin serta pasca kemoterapi metoklopramid-ranitidin. Rasionalitas penggunaan obat antiemetik pada pasien kanker ovarium pasca kemoterapi sebagian besar sudah sesuai. Kata kunci: antiemetik, kanker ovarium, kemoterapi, rasionalitas
Subcorneal Pustular Dermatosis Dengan Diabetes Melitus Tipe 2 dan Dislipidemia: Sebuah Laporan Kasus Gustia, Rina; Muchyar, Mutia Sari; Ashar, Miranda; Imaduddin, Ummul Khair; Intan, Shinta Ayu; Oktora, Meta Zulyati
Scientific Journal Vol. 5 No. 1 (2026): SCIENA Volume V No 1, January 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i1.331

Abstract

Pendahuluan: Subcorneal pustular dermatosis (SPD), atau penyakit Sneddon–Wilkinson, merupakan dermatosis neutrofilik kronis yang jarang, ditandai dengan pustul superfisial berulang. SPD semakin banyak dilaporkan berhubungan dengan penyakit sistemik, terutama gangguan metabolik seperti diabetes melitus tipe 2 dan dislipidemia, yang dapat berkontribusi terhadap onset dan kekambuhan penyakit. Laporan kasus: Seorang perempuan berusia 36 tahun yang datang dengan keluhan bercak kemerahan berulang disertai pustul superfisial flaksid berwarna kekuningan yang gatal pada daerah perut dan punggung bawah selama dua bulan terakhir. Lesi awalnya membaik dengan kortikosteroid topikal tetapi kambuh kembali dua minggu kemudian dengan cakupan yang lebih luas. Pasien tidak mengeluhkan demam maupun riwayat konsumsi obat sebelumnya. Pasien memiliki penyakit dasar diabetes melitus tipe 2 dan dislipidemia, keduanya dalam kondisi tidak terkontrol dengan baik. Pemeriksaan klinis menunjukkan plak eritematosa multipel dengan pustul superfisial, krusta, erosi, serta makula hiperpigmentasi pada perut dan punggung bawah. Pemeriksaan dermoskopi menunjukkan multiple yellow-white globule di atas dasar eritematosa yang dikelilingi sisik halus. Evaluasi psikologis menunjukkan tingkat kecemasan sedang dan dampak sedang terhadap kualitas hidup.  Kesimpulan: Kasus ini menekankan pentingnya mengevaluasi dan menangani komorbiditas sistemik, karena disfungsi metabolik dapat berkontribusi terhadap inflamasi persisten, kekambuhan berulang, dan respons terapi yang kurang optimal pada Subcorneal Pustular Dermatosis.
Perbedaan Fungsi Ventrikel Kanan pada Pasien Hipertensi Arteri Pulmonal Akibat Penyakit Jantung Bawaan dan Tanpa Penyakit Jantung Bawaan Fatimah Azzahra; Mefri Yanni; Erlina Rustam; Noverika Windasari; Shinta Ayu Intan
Jurnal Ilmu Kedokteran Vol 20, No 1 (2026): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v20i1.2026.94-104

Abstract

Pulmonary arterial hypertension (PAH) leads to right ventricular (RV) dysfunction due to chronic volume overload in congenital heart disease (CHD) or pressure overload in isolated PAH. This study aimed to evaluate differences in RV function between PAH patients with and without CHD, given their distinct pathophysiological mechanisms. A cross-sectional analytical study was conducted using medical records from Dr. M. Djamil Padang Hospital (2023–2024), including 54 patients (27 per group) selected via consecutive sampling. Bivariate analysis using the Chi-square test was employed to compare standard echocardiographic parameters: three-dimensional ejection fraction (3DEF), tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), S', and RV Strain. The results revealed no significant differences in RV function parameters between the two groups: 3DEF (p=0.773), TAPSE (p=0.293), FAC (p=0.224), S' (p=1.000), and RV Strain (p=0.559). Furthermore, median values for 3DEF, TAPSE, FAC, and S' were within normal limits, whereas mean RV Strain values were in the abnormal range for both study groups. In conclusion, despite the differing underlying pathophysiologies, there is no significant difference in right ventricular function between patients with PAH due to CHD and those without CHD.