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All Journal Journal of Food and Pharmaceutical Science Jurnal Penelitian Farmasi Indonesia Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Majalah Obat Tradisional Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Science and Technology Indonesia Jurnal Penelitian Farmasi Indonesia Pharmacology and Clinical Pharmacy Research JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PENDIDIKAN TAMBUSAI PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmu Kefarmasian Indonesia Majalah Farmasetika Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Katalisator Journal of Food and Pharmaceutical Sciences Jurnal Manajemen Rekayasa (Journal of Engineering Management) Usadha Journal of Pharmacy Jurnal Medika: Medika Jurnal Bakti Nusantara Medical Sains : Jurnal Ilmiah Kefarmasian
Deni Anggraini
Sekolah Tinggi Ilmu Farmasi Riau
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Formulasi Sabun Cair dari Ekstrak Batang Nanas (Ananas comosus. L ) untuk Mengatasi Jamur Candida albicans Anggraini, Deni; Rahmides, Wiwik Sri; Malik, Masril
Jurnal Penelitian Farmasi Indonesia Vol 1, No 01 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

A study on antifungal effect of liquid soap formulation of extract of pineapple stem (Ananas comosus L) has been carried out towardsCandida albicans. Three different concentrations of extract 3; 5 and 7%, were formulated as liquid soap using TEA, stearic acid andglycerine as its soap bases. Several evaluations were examined on the liquid soap formulation including organoleptic examination, determinationof relative density, viscosity, foam test, pH test, and skin irritation test. While antifungal effect test of the obtained formulations was testedon PDA medium. The result revealed that extract of pineapple stem was successfully formulated and physically stable in liquid soap form.The antifungal effect test showed that formula with 7% concentration of extract demonstrated the strongest effect with 21.3 mm diameterof inhibition towards Candida albicans.
Formulasi Gel Antijerawat dari Ekstrak Etil Asetat Gambir Anggraini, Deni; Rahmawati, Noveri; Hafsah, Siti
Jurnal Penelitian Farmasi Indonesia Vol 1, No 2 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

The formulas of antiacne gel preparation of ethyl acetate extract of gambir have been formulated by using carbopol 940P as its bases. In thisstudy, five difference gel formulas F1, F2, F3, F4 and F5, were prepared with 0.5; 1; 2; 4 and 6% of concentration of extract, respectively.The result showed that organoleptic of al formulas was found unstable, while the appearance of gel F1 and F2 were homogeneous and stableat room temperature as well as cooling process. In addition, all formulas exhibited stable value in pH evaluation and did not irritate the skin.
Pembuatan dan Uji Sifat Fisikokimia Pati Beras Ketan Kampar yang Dipragelatinasi Lukman, Anita; Anggraini, Deni; Rahmawati, Noveri; Suhaeni, Nani
Jurnal Penelitian Farmasi Indonesia Vol 1, No 2 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

Glutinous rice contains 99.7% of amilopectin. The amilopectin does not swell in cold water and it could retard the desintegration anddissolution of drug. Physical modification of glutinous rice by pregelatization can enhance the swelling power of starch in cold water. In thisstudy, glutinous rice used as sample was collected from three difference places which are kecamatan Air Tiris, Rumbio Jaya dan Salo kabupatenKampar, Riau province. Sample was subjected to pregelatization process manually as well as by using Spray Dryer. The result showed thatpregelatized glutinous rice starch gave the higher swelling power than glutinous rice. Glutinous rice from Rumbio Jaya showed the highestswelling power of 343.87%. This value indicated that it could be potential candidate as sustained release agent.
Physicochemical Properties of Phosphate Pregelatinized Musa balbisiana Starch as Pharmaceutical Excipient Anggraini, Deni; Lukman, Anita; Teruna, Hilwan Y.
Pharmacology and Clinical Pharmacy Research Vol 1, No 3
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (676.153 KB) | DOI: 10.15416/pcpr.v1i3.15398

Abstract

Starch is among the important pharmaceutical excipient, which is particularly used as filler in the tablet formulation and suspending agent. Starch from natural source has a potential to be developed as pharmaceutical excipient with comparable characteristics, including starch from Musa balbisiana (M. balbisiana). This study aimed to synthesize and evaluate physicochemical properties of phosphate pregelatinized M. balbisiana starch. We isolated the starch from M. balbisiana and performed pregelatinization. Since pregelatinized starch still could experience retrogradation which cause syneresis, chemical modification of pre-gelatinized starch was conducted using 5% of sodium tripolyphosphate at pH of 9-10. Physicochemical properties of phosphate pregelatinized starch were then investigated. It included the assessment of its organoleptic, pH, water content, particle size distribution, angle of repose, swelling power, amylose content, adsorbs isotherm, and particle analysis using Scanning Electron Microscope (SEM). Phosphate-pregelatinized M. balbisiana starch had low swelling power, better flow properties and viscosity. It can be used particularly in the formulation of slow released tablets and suspending agents in suspension formula.Keywords: pregelatinized starch, Musa balbisiana, psychochemical properties, excipients
Efektifitas Krim Papain Kasar Getah Buah Pepaya (Carica Papaya.L) yang Diolah Dengan Metode Freeze Drying Terhadap Penyembuhan Penebalan Kulit (Callus) Anggraini, Deni
Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Vol 6, No 1 (2020): Pharmauho
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/pharmauho.v6i1.10407

Abstract

Telah dilakukan penelitian uji efektivitas krim papain kasar getah buah papaya (Carica papaya L) yang diolah dengan metode freeze drying terhadap penyembuhan penebalan kulit (Callus). Penelitian ini bertujuan untuk mengetahui efektivitas proteolitik  dari papain kasar dalam penyembuhan Callus yang diolah dengan metode freeze drying. Formula dibuat dengan memvariasikan konsentrasi papain kasar getah buah papaya (Carica papaya L) 10%, 15%, dan 20% dengan pemilihan tipe krim A/M. Evaluasi sediaan krim yang dilakukan meliputi organoleptis, homogenitas, pH, stabilitas suhu, daya tercuci krim, daya menyebar dan uji iritasi kulit. Dari hasil penelitian diperoleh papain kasar getah buah papaya (Carica papaya L) dapat diformulasi dalam bentuk krim untuk penyembuhan penebalan kulit (Callus). Hasil pengurangan diameter Callus pada konsentrasi 10% yaitu A 0,65 cm, B 0,65 cm, C 0,35 cm, konsentrasi 15% yaitu A 0,4 cm, B 0,6 cm, C 0,6 cm, dan konsentrasi 20% yaitu A 1,25 cm, B 0,5 cm, C 0,7 cm. Krim papain kasar getah buah papaya (Carica papaya L) konsentrasi 20% dibandingkan dengan kontrol positif krim asam salisilat 20% belum memberikan efektivitas cukup baik.
Physicochemical Properties of Phosphate Pregelatinized Musa balbisiana Starch as Pharmaceutical Excipient Deni Anggraini; Anita Lukman; Hilwan Y. Teruna
Pharmacology and Clinical Pharmacy Research Vol 1, No 3
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (676.153 KB) | DOI: 10.15416/pcpr.v1i3.15398

Abstract

Starch is among the important pharmaceutical excipient, which is particularly used as filler in the tablet formulation and suspending agent. Starch from natural source has a potential to be developed as pharmaceutical excipient with comparable characteristics, including starch from Musa balbisiana (M. balbisiana). This study aimed to synthesize and evaluate physicochemical properties of phosphate pregelatinized M. balbisiana starch. We isolated the starch from M. balbisiana and performed pregelatinization. Since pregelatinized starch still could experience retrogradation which cause syneresis, chemical modification of pre-gelatinized starch was conducted using 5% of sodium tripolyphosphate at pH of 9-10. Physicochemical properties of phosphate pregelatinized starch were then investigated. It included the assessment of its organoleptic, pH, water content, particle size distribution, angle of repose, swelling power, amylose content, adsorbs isotherm, and particle analysis using Scanning Electron Microscope (SEM). Phosphate-pregelatinized M. balbisiana starch had low swelling power, better flow properties and viscosity. It can be used particularly in the formulation of slow released tablets and suspending agents in suspension formula.Keywords: pregelatinized starch, Musa balbisiana, psychochemical properties, excipients
Pembuatan Dan Evaluasi Pati Talas (Colocasia esculenta Schoot) Termodifikasi dengan Bakteri Asam Laktat (Lactobacillus sp) Wira Noviana Suhery; Deni Anggraini; Novtafia Endri
Jurnal Sains Farmasi & Klinis Vol 1, No 2 (2015): J Sains Farm Klin 1(2), Mei 2015
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.149 KB) | DOI: 10.29208/jsfk.2015.1.2.36

Abstract

Production and evaluation of modified taro (Colocasia esculenta Schott) starch by lactic acid bacteria (Lactobacillus sp) has been done. The purpose of this study was to observe the effect of lactic acid bacteria to the yield of taro starch and to evaluate physicochemical of starch. The evaluation which includes organoleptic, moisture content, pH, angle of repose, swelling power, gelatination temperature, amylose content, and examination of the surface shape of starch granules using SEM (Scanning Electron Microscope). The result showed that modified taro starch yield higher (19,12%) than native taro starch (11,79%). Modified taro starch of organoleptic examination showed better results where the smell was slighly reduced and the colour was white. Meanwhile, from the results of the evaluation of swelling power, gelatination temperature, and amylose content showed an increase. In addition, the modified taro starch granule were rougher due to some holes presented distinctively.
Formulasi Tablet Lepas Lambat Natrium Diklofenak Menggunakan Pati Pisang Kepok (Musa balbisiana L) Sebagai Matriks Deni Anggraini; Anita Lukman; Ria Mulyani
Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.152 KB) | DOI: 10.29208/jsfk.2016.3.1.93

Abstract

Telah dilakukan formulasi tablet lepas lambat Natrium Diklofenak menggunakan matriks pati pisang kepok dan natrium karboksil metil selulosa sebagai pembandingnya. Tujuan penelitian ini untuk mengetahui apakah sediaan lepas lambat yang dibuat dengan matriks pati pisang kepok memenuhi persyaratan tablet lepas lambat. Hasil uji disolusi menunjukan formula I (Pati Pisang Kepok) terdisolusi sebesar 110,24 %, formula II (Natrium Karboksil Metil Selulosa) sebesar 39,04 % dalam waktu 8 jam. Dari hasil uji disolusi menunjukan bahwa pati pisang kepok belum memenuhi persyaratan sebagai matriks karena belum dapat memperlambat laju disolusi. Kinetika pelepasan zat aktif dari matriks antara kedua formula mengikuti persamaan Higuchi.
Formulasi Gel Sarang Burung Walet Putih (Aerodramus fushipagus) dan Uji Penyembuhan Luka Bakar Derajat II pada Mencit Deni Anggraini; Lisa Yunus Kasmawati
Jurnal Sains Farmasi & Klinis Vol 4, No 1 (2017): J Sains Farm Klin 4(1), November 2017
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.185 KB) | DOI: 10.29208/jsfk.2017.4.1.172

Abstract

Formulasi gel sarang burung walet putih (Aerodramus fushipagus) dan uji penyembuhan luka bakar derajat II pada mencit putih (Mus musculus) jantan telah dilakukan. Penelitian ini bertujuan untuk memformulasikan sediaan gel dari bahan aktif sarang burung walet putih dengan konsentrasi 10%, 20% dan 30% dan melihat efek penyembuhan luka bakar pada kulit mencit. Uji penyembuhan luka bakar dilakukan terhadap 15 ekor mencit putih jantan yang dibagi menjadi 5 kelompok perlakuan yaitu, kontrol negatif (basis gel), kontrol positif dan kelompok perlakuan formula 10%, 20% dan 30%. Luka bakar diinduksi pada bagian punggung dengan diameter 2 cm dengan menggunakan logam panas. Hewan diberi perlakuan dan diameter luka diukur setiap hari selama 21 hari. Hasil evaluasi terhadap gel menunjukkan semua formula homogen, stabil terhadap suhu dan tidak mengiritasi kulit. Uji statistik ANOVA dua arah terhadap persentase penyembuhan luka bakar menunjukkan bahwa terdapat perbedaan yang signifikan antara penyembuhan luka bakar pada kelompok perlakuan dengan kelompok kontrol. Penelitian ini menyimpulkan bahwa ketiga formula memberikan efek penyembuhan luka bakar yang lebih baik dibandingkan kontrol.
Analisis Sistem Penyimpanan Obat di Instalasi Farmasi Dinas Kesehatan Kabupaten Rokan Hulu Tahun 2018 Deni Anggraini; Syarifah Merlina
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 17 No. 01 Juli 2020
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v17i1.5096

Abstract

Penyimpanan obat yang baik  penting untuk menjaga persediaan obat agar terhindar dari kerusakan, kadaluwarsa, dan untuk menjaga mutu. Tujuan penelitian ini adalah untuk mengetahui kesesuaian sistem penyimpanan obat di Instalasi Farmasi Dinas Kesehatan Kabupaten Rokan Hulu berdasarkan 5 indikator penyimpanan obat. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif dengan pengumpulan data secara retrospektif dari bulan Januari sampai Desember 2018. Pengumpulan data dilakukan dengan observasi dan telaah dokumen. Hasil penelitian menunjukkan bahwa untuk parameter sistem penataan gudang dan parameter kesesuaian antara obat dengan kartu stok hasilnya kategori sangat baik. Persentase nilai obat rusak dan kadaluwarsa memenuhi persyaratan yaitu <1% (0,33%). nilai Turn Over Ratio (TOR) 0,85 kali, dan persentase stok mati 2,78% belum memenuhi persyaratan (0%).
Co-Authors Abdul Kadir Adela, Syarifah Nur Adris Ade Putra agistia, nesa Agistia, Nesa Aina Novalia Al-Fadillah, Annsisya Shafira Amanda Yulia Amanda, Denisya Anggraini, Dhiva Anita Lukman Anita Lukman Anita Lukman Anita Lukman Anita Lukman Annisa Annisa Armon Fernando Astaharie, Shinta Angelia Azhar, Gustika Azizah, Nur Rahmi Azli, Echa Saskia Benni Iskandar Delvi Dira Repuja Eliza Fitri Enda Mora Erizal Zaini Ezuela, Deska Z Fathur Rahman Fitri Mulyani, Fitri Furi, Mustika Gressy Novita Gressy Novita Haiyul Fadhli Hilwan Y. Teruna Hulwa Salsabila Idzan, Nur Kamilah Ihsan Ikhtiarudin Indriana, Annisa Chika Ayu Jasma Jasma K, Della Yunita Sary. Kurnia, Lisa Lisa Yunus Kasmawati M Almurdani M. Almurdani Maria Susiladewi Masril Malik Meiriza Djohari, Meiriza Melanie, Claudy Friesta Melzi Octaviani Mia Audina, Mia Musyirna Rahmah Nst N Nurfieftien Nabela, Nabela Nadia, Putri Nani Suhaeni Nofri Hendri Sandi Noveri Rahmawati Novtafia Endri Nurul Elisa Pratiwi, Wulan Iska Prima Aulia Putra Rajeb Fadillah Repuja, Dira Ria Mulyani Rodhia Ulfa Rodhia Ulfa Safitri, Elsa Salman Umar Sandra, Alya Dwi Sandry Eka Saputri Nst Sari, Fatwa Aulia Sinata, Novia Siti Hafsah Suhada, Zikra Sukma Sukma Suwinda, Elia Syarifah Merlina T. Harpirabi Tami Tami Teruna, Hilwan Y. Wildan Rasyid Wira Noviana, Wira Noviana Wirahma Indah Pratiwi Wiwik Sri Rahmides Wulandari, Intan Wulandari, Lydia Tri Yadi, Hervi Yufri Aldi Yulia, Amanda Zalfa Desion, Aufa Zikrinnissa, Zikrinnissa