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Isolasi Senyawa dan Uji Aktivitas Anti-inflammasi Ekstrak Metanol Daun Puwar Kincung (Nicolaia speciosa Horan) Fernando, Armon; Suryani, Fitri; Ahmad, Farediah; Sirat, Hasnah M.; Arbain, Dayar
Jurnal Penelitian Farmasi Indonesia Vol 1, No 01 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

The study of anti-inflammatory activity and isolation of the methanolic extract, hexane and ethyl acetate fractions of the leaves of puwarkincung (Nicolaia speciosa Horan) have been done. Isolation was carried out by extraction, fractionation and multiple column chromatographicmethod, followed by recrystallization technique. Two compounds were isolated and labeled as F4 and S3. F4 was derived from n-hexanefraction as yellowish-white crystals (20 mg) with mp. 55–57 oC and S3 from the ethyl acetate fraction (15 mg) as yellow crystals with mp.68–69 oC. Anti-inflammatory activity of methanolic extract using Paw Edema method showed that the dose 250 and 1000mg/kgbw wereactive as anti inflammatory agents.
Optimasi Ekstraksi Triterpenoid Total Pegagan (Centella asiatica (Linn.) Urban) yang Tumbuh di Riau Mora, Enda; Fernando, Armon
Jurnal Penelitian Farmasi Indonesia Vol 1, No 01 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

Optimization of extraction of total triterpenoid content from pegagan (Centela asiatica (Linn) Urban) originated from three locations inRiau province; kecamatan Siak Hulu, kabupaten Kampar, kecamatan Belilas, kabupaten Pelalawan and kecamatan Tampan kota Pekanbaruwas carried out using soxhlet method. n-Hexane and methanol were used as eluent and 8 grams of active carbon as adsorbent. The resultrevealed that pegagan originated from kabupaten Kampar showed the highest yield with total triterpenoid content of 3.94%, while otherspegagan afforded lower yield; 1.25% for kabupaten pelalawan and 1.91% for kota Pekanbaru.
ANALISA BENSORSAK SECARA KROMATOGRAFI CAIR KINERJA TINGGI: STUDI KASUS SAMPEL SAOS SAMBAL DARI INDUSTRI RUMAH TANGGA DI PEKANBARU Nasution, Musyirna Rahmah; Fernando, Armon; -, Suhelmi
Sistem Informasi Vol 2 No 2 (2012): Jurnal Photon
Publisher : Fakultas MIPA dan Kesehatan Universitas Muhammadiyah Riau

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Abstract

Natrium benzoat, kalium sorbat dan natrium sakarin merupakan bahan pengawet dan pemanis yang digunakan dalam makanan dan minuman. Telah dilakukan penentuan kadar natrium benzoat, kalium sorbat dan natrium sakarin (BENSORSAK) dalam saos sambal produksi industri rumah tangga dengan menggunakan Kromatografi Cair Kinerja Tinggi (KCKT). Kadar natrium benzoat untuk sampel A 2.577,33 mg/kg, sampel B 858,25 mg/kg, sampel C 1.905,88 mg/kg dan sampel D 2.295,83 mg/kg. Kadar natrium benzoat pada Sampel A, C dan D melebihi batas maksimal Menteri Kesehatan RI No 722 / IX / 88, yaitu 1 g/kg untuk asam benzoat atau garamnya. Kadar natrium sakarin yang terdapat pada sampel B 129,98 mg/kg dan sampel C 133,01 mg/kg masih dalam batas yang ditetapkan PerMenkes RI yaitu 0,5 g/kg. Sedangkan kalium sorbat tidak ditemukan dalam sampel saos sambal.
PENYULUHAN TENTANG UPAYA PENCEGAHAN SERTA POLA HIDUP SEHAT DIMASA PANDEMI COVID-19 DAN BERBAGI MASKER GRATIS DI KOTA PEKANBARU DAN SEKITARNYA Benni Iskandar; Tiara Tri Agustini; Ferdy Firmansyah; Neni Frimayanti; Armon Fernando; Wildan Khairi Muhtadi
COVIT (Community Service of Health) Vol. 2 No. 1 (2022): MARET 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

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Abstract

At the beginning of 2020, the world was shocked by the outbreak of a new virus, The new type of Corona Virus (SARS-CoV-2) and the disease is called Corona Virus Disease 2019 (COVID-19). It is known that the origin of this virus originated in Wuhan, China, was discovered at the end of 2019. Until now, it has been confirmed that there are 65 countries that have contracted this virus (WHO data March 1, 2020). Among all these countries, Indonesia is one of the countries that is also affected or infected by the Corona virus outbreak. As of April 2020, more than 1000 people have died according to data recorded at the Ministry of Health of the Republic of Indonesia. This is of course a special concern for all circles. This activity aims to provide education about the meaning and dangers of COVID-19 and distribute free masks to the public. The method of implementing this activity is by providing health education about COVID-19 and distributing protective masks for free. People who received education and received masks for free seemed enthusiastic about the service activities being held, it was seen from the seriousness of the community in listening to the material and reading the educational brochures provided.
Sosialisasi pencegahan dan pengendalian Infeksi Saluran Nafas Akut di Wilayah XIII Koto Kampar Rahmayati Rusnedy; Adriani Susanty; Rickha Octavia; Nofri Hendri Sandi; Ferdy Firmansyah; Armon Fernando
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 2 (2020): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.702 KB) | DOI: 10.29303/indra.v1i2.28

Abstract

Acute Respiratory Infection (ARI) is one of the highest infectious diseases in Indonesia that can cause death. The public knowledge about the prevention and control of ARI is inadequate, so prevention efforts are needed to reduce the transmission of this infection disease. The purpose of this community service activity is to increase the knowledge of the people of Gunung Bungsu Village, Kec. XIII Koto Kampar on preventing the transmission of ARIs through preventive measures by providing education on how to use masks and proper ethics when coughing/sneezing. The method used was an interactive and participatory model by involving the community at Gunung Bungsu Village, Kec. XIII Koto Kampar. This socialization activity increased the community knowledge, showed by the enthusiasm of community at Gunung Bungsu Village, Kec. XIII Koto Kampar who actively interacts through the questions they ask to increase their understanding of ARI. Beside that, the results of the questionnaire assessment showed that the community was satisfy with the socialization of ARI prevention. This service can be useful for the prevention and control of ARI around the neighborhood.
Aktivitas Daya Hambat Ekstrak Etanol Biji Pinang (Areca catechu L.) terhadap Isolat Bakteri Gigi Meiriza Djohari; Armon Fernando; Annisa Safitri
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 1 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.052 KB) | DOI: 10.35814/jifi.v18i1.721

Abstract

Areca nut is traditionally used by the community to strengthen teeth. Areca nuts contain alkaloid, flavonoid, and terpenoid as antibacterials. This study aims to determine the types of dental bacteria resulting from isolates and determine the effect of the administration of ethanol extract of areca nut (Areca catechu L.) on the results of isolates of dental bacteria. Antibacterial activity testing using disc diffusion method with the concentration of areca nut ethanol extract 10%, 20% and 30%. The results showed that bacteria of the tooth are Lactobacillus casei, Branhamella catarrhalis, Streptococcus sp. Ethanol extract of areca nut (Areca catechu L.) is better to inhibit the growth of Lactobacillus casei compared to Branhamella catarrhalis and Streptococcus sp in the medium to weak category. Two Way ANOVA test results on inhibitory zone diameter stated that there were differences between the concentration groups of 10%, 20%, 30%, positive control and negative controls and there were differences in the inhibitory activity of Lactobacillus casei compared to Branhamella catarrhalis and Streptococcus sp but there were no significant differences on the inhibitory activity of Branhamella catarrhalis with Streptococcus sp.
Perbandingan Metode Granulasi Basah dan Kempa Langsung Terhadap Sifat Fisik dan Waktu Hancur Orally Disintegrating Tablets (ODTs) Piroksikam Wira Noviana Suhery; Armon Fernando; Buddy Giovanni
Jurnal Sains Farmasi & Klinis Vol 2, No 2 (2016): J Sains Farm Klin 2(2), Mei 2016
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.701 KB) | DOI: 10.29208/jsfk.2016.2.2.65

Abstract

Study on comparison of wet granulation and direct compression method of physical properties and disintegration time of orally disintegrating tablets piroxicam has been done. This study aims to comparison which method gives better results of physical properties and disintegration time between wet granulation and direct compression method. Both methods are made with the same composition formula of each tablets is Piroxicam 20 mg, Primellose® 5%, 1% PVP K30, magnesium stearate 1%, Mannitol 10%, and Comprecel® up to 175 mg. ODTs then evaluated physical properties which include weight variation, thickness, hardness, friability and friksibility, disintegration time, ratio of water absorption, wetting time, drug content and dissolution test. The results showed that both methods produce the physical properties of a good tablets. However, the method of direct compression provides a disintegrating faster 55.51 seconds compared with the wet granulation method. Statistical test using independent sample T test showed that there were significant differences in the disintegration time (P <0.05) between the formula with the method of direct compression and wet granulation.
Penetapan Kadar Berberin dari Ekstrak Etanol Akar dan Batang Sekunyit (Fibraurea Tinctoria Lour) dengan Metode KCKT Rahayu Utami; Armon Fernando; Indah Puspita Sari; Mustika Furi
Jurnal Sains Farmasi & Klinis Vol 3, No 2 (2017): J Sains Farm Klin 3(2), Mei 2017
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.887 KB) | DOI: 10.29208/jsfk.2017.3.2.84

Abstract

Determination of berberine content of ethanol extract of root and stem of “sekunyit” (Fibraurea tinctoria Lour) has been conducted. “Sekunyit” is one of medicinal plant that has been used to treat several diseases traditionally. Its root and stem could relieve jaundice, diarrhea, conjunctivitis as well as antidiabetic agent. Based on previous study, it is known that Fibraurea tinctoria contains isoquinoline alkaloid, berberine. This present study aims to determine berberine content which was done by HPLC (High Performance Liquid Chromatography) method using C-18 reverse phase column, methanol : phosphate buffer (pH 6,8) as its mobile phase with flow rate of 1 ml/min and UV detector. The analysis was performed at wavelength 346 nm. The result showed that the ethanol extract contains 25.8% of berberine
Efek Analgetik Ekstrak Etanol Daun Tampa Badak (Voacanga foetida (Bl.) K. Schum) Pada Mencit Putih Jantan Adriani Susanty; Armon Fernando; Ivona Adelin
Jurnal Sains Farmasi & Klinis Vol 1, No 1 (2014): J Sains Farm Klin 1(1), November 2014
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.505 KB) | DOI: 10.29208/jsfk.2014.1.1.19

Abstract

A study on the analgesic activity ethanolic extract of Voacanga foetida leaves has been conducted on male mice by using Writhing test. The mice were induced with 0.1 mL of glacial acetic acid 1%. The extract was administered orally in the doses of 250, 500, and 1000 mg/kg, suspended with NaCMC 1%, while 65 mg/kg acetosal was used as positive control. The data was analyzed with two way ANOVA. The study revealed that the extract exhibited analgesic effect insignificantly different with acetosal at the doses of 250, 500, and 1000 mg/kg. This effect was different with negative control (p<0.05).
ANALISA BENSORSAK SECARA KROMATOGRAFI CAIR KINERJA TINGGI: STUDI KASUS SAMPEL SAOS SAMBAL DARI INDUSTRI RUMAH TANGGA DI PEKANBARU Musyirna Rahmah Nasution; Armon Fernando; Suhelmi -
Sistem Informasi Vol 2 No 2 (2012): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v2i2.137

Abstract

Natrium benzoat, kalium sorbat dan natrium sakarin merupakan bahan pengawet dan pemanis yang digunakan dalam makanan dan minuman. Telah dilakukan penentuan kadar natrium benzoat, kalium sorbat dan natrium sakarin (BENSORSAK) dalam saos sambal produksi industri rumah tangga dengan menggunakan Kromatografi Cair Kinerja Tinggi (KCKT). Kadar natrium benzoat untuk sampel A 2.577,33 mg/kg, sampel B 858,25 mg/kg, sampel C 1.905,88 mg/kg dan sampel D 2.295,83 mg/kg. Kadar natrium benzoat pada Sampel A, C dan D melebihi batas maksimal Menteri Kesehatan RI No 722 / IX / 88, yaitu 1 g/kg untuk asam benzoat atau garamnya. Kadar natrium sakarin yang terdapat pada sampel B 129,98 mg/kg dan sampel C 133,01 mg/kg masih dalam batas yang ditetapkan PerMenkes RI yaitu 0,5 g/kg. Sedangkan kalium sorbat tidak ditemukan dalam sampel saos sambal.
Co-Authors Adriani Susanty Agistia, Nesa agistia, nesa Agustini, Tiara Tri Ainun Alfatma Allaya, Regina Alpatiqa, Silviana Lufti, Siti Hizra Amanda Yulia Amin, Syahrul Anita Lukman Annisa Safitri Arief, Encik Juliansyah Aulia, Nada Aqilah Azkia Wanudya Rahmadhani Benni Iskandar Buddy Giovanni DAYAR ARBAIN Deni Anggraini Dira Repuja Dwi Winarsih Elsa Safitri Enda Mora Fadhilatun Khoiriyah Farediah Ahmad Farisa, Nayla Al Ferdy Firmansyah Fina Aryani, Fina Fitri Suryani Furi, Mustika Gressy Novita Haiyul Fadhli Hariyani, Widya Hasnah M. Sirat Hayu Lestari Hefriza Putri Husnawati Ihsan Ikhtiarudin Indah Puspita Sari Indri Aprilia, Indri Irfan, Nawwar Ivona Adelin Jannati, Nisa Jumadila, Ikhsal Mukri Kolista Sisilawati M. Almurdani Maryunita, Dinda Mayrade, Salma Yudhistira Meiriza Djohari, Meiriza Melzi Octaviani Meyrika Putri Wandala Milianty, Jesy Muhtadi, Wildan Khairi Musyirna Rahmah Nst Neni Frimayanti Netralis Has Ningrum, Tilar Eka Widia Nofri Hendri Sandi Nurul Elisa Putri Lestari Putri Lestari, Putri Putri, Dhini Fahira Rahayu Utami Rahayu Utami Rahma Dona Rahma, Indah Lutfianti Rahma, Rizqia I’zza Rahmah, Rizka I’zaa Rahmayanı, Wıky Rajeb Fadillah Ramona, Paula Repuja, Dira Rickha Octavia Rusnedy, Rahmayati Sadam Husein Safira, Yola Safitri, Fasri Dian Septi Muharni Suci Bettiza Oktarisma Suhelmi - Suhelmi - Syafutri, Lidiyah Syahbandi, Ilham Syilfia Hasti Tengku Yuni Atika S Tiara Salsabila P.A Tita Adhaha F Venny Wulandari Victriani Sitohang Winda Sari Winda Windiati Wira Noviana, Wira Noviana Yeni Karlina Yulia, Amanda Yulius Mubharroq Zakiyah Manaf