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Sofia Sandi
Universitas Sriwijaya
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Journal : Science and Technology Indonesia

 1 
The submicron particles FORMULATION OF IONIC-GELATION SUBMICRON PARTICLES LOADING EXTRACT PAPAYA LEAVES (Carica papaya L.) WITH LACTIC ACID ISOLATES Mardiyanto, Mardiyanto; Untari, Budi; Fithri, Najma Annuria; Sandi, Sofia; Mawaddah, Zahrul
Science and Technology Indonesia Vol 4 No 3 (2019): July
Publisher : ARTS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1762.875 KB) | DOI: 10.26554/sti.2019.4.3.77-81

Abstract

A study regarding ionic-gelation submicron particle of papaya leaves (Carica papaya L.) extract with lactic acid of weeds potentially for antidiarrhea has been conducted. Preparation of papaya leaves ethanolic extract and lactic acid isolate into particles was done by ionic gelation method. This study aimed to determine: the major compound of extract, the total quercertine of extract, the percent value of encapsulation efficiency of the optimum formula which was varied by (CaOH)2 of the three formulas, and physical properties of particles. Formula 1 was using (CaOH)2 of 12.5 gram; formula 2 (CaOH)2 of 17,5 gram; formula 3 (CaOH)2 of 22.5 gram. The results showed formula 1 as the optimum formula that has the highest %EE. The average %EE values ??of F1; F2; F3 respectively were 80,82%; 80,41%; 80,31%. The results of particle characterization using the PSA in the optimum formula produced particle size values ??with an average of 253.6 nm, PDI of 0.218, and zeta potential +8 mV respectively.
Co-Authors Ade Dwi Sasanti Adi Supriyadi ali, asep indra munawar Apriansyah Susanda ARINAFRIL ARINAFRIL Asep Indra M. Ali Asep Sudarman Asmak Asmak Asmak Asmak asmak asmak Avin Bastian Bambang Gunawan Budi Untari Chandra Irsan Djumali Mangunwijaja Dyah Wahyuni Dyah Wahyuni Eli Sahara Eli Sahara Eli Sahara Eli Sahara Eli Sahara Eli Sahara Elisahara Elisahara Erika B. Laconi Erra Kartika Erra Kartika, Erra F. Yosi Fitra Yosi Fitra Yosi Fitra Yosi fitra yosi, fitra Fitra Yossi Harian Saputra Hermansyah Hermansyah I Komang Gede Wiryawan Mardiyanto Mardiyanto Mawaddah, Zahrul Meisji Liana Sari Miksusanti Miksusanti Muhakka Muhakka Mutia Nurrahmandani Najma Annuria Fithri, Najma Annuria Nasir Rofiq Nasir Rofiq Nugroho Arianto NUNI GOFAR Oktaviani Oktaviani Pungky Oktavia Rahmat Pratama, Rahmat Riswandi Riswandi Robi Alexa RR. Ella Evrita Hestiandari saka puspa wijaya Sarah Pratiwi SITI HERLINDA Sofi Arisuteja, Sofi Sulistyani, Dwi Probowati Susilawati, Susilawati Weri Herlin YULIA PUJIASTUTI