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All Journal Nexus Pendidikan Kedokteran dan Kesehatan Nexus Kedokteran Klinik Nexus Biomedika Nexus Kedokteran Translasional Journal of Epidemiology and Public Health Indonesian Journal of Medicine Jurnal Respirasi (JR)
Leli Saptawati
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Journal : Nexus Kedokteran Translasional

 1 
The Effectiveness of the Leaf Extract of Jati Belanda (Guazuma ulmifolia Lamk) as Dengue Antiviral In Vitro Pratiwi, Yani Dwi; Saptawati, Leli; Marufah, Siti
Nexus Kedokteran Translasional Vol 6, No 1 (2017): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Dengue Haemorrhagic Fever is one of a serious disease in the world because it can cause death. During all these years, DHF in Indonesia only treated by symptomatic and supportive therapy. The purpose of this study was to determine the effectiveness of Jati Belanda leaf’s extracts as antiviral dengue in vitro. Methods: The method used is pure experimental research and the research design method is post test only control group design. The subject is dengue virus serotype 2 strain New GuineaC (DENV2 NGC) obtained from the Laboratory of Virology and Molecular Biology Department of Microbiology, Faculty of Medicine, University of Indonesiaand this research was started from June until November 2016. The independent variables in this study is the concentration of Jati Belanda leaf’s extracts obtained from Pharmaceutical Laboratory of Faculty Pharmacy, Gadjah Mada University and dependent variable are infectivity value and viability value. The collected data are presented in tables. Results:In concentration 40 µg/ml, the infectivity value is 12.6% and the viability value is 91.4%. Conclusions: The leaf extracts of Jati Belanda is potentially effective as antiviral dengue. Keywords: dengue, Jati Belanda extract, antivirus, DHF  
The Effectiveness of the Leaf Extract of Jati Belanda (Guazuma ulmifolia Lamk) as Dengue Antiviral In Vitro Yani Dwi Pratiwi; Leli Saptawati; Siti Marufah
Nexus Kedokteran Translasional Vol 6, No 1 (2017): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.209 KB)

Abstract

Introduction: Dengue Haemorrhagic Fever is one of a serious disease in the world because it can cause death. During all these years, DHF in Indonesia only treated by symptomatic and supportive therapy. The purpose of this study was to determine the effectiveness of Jati Belanda leafs extracts as antiviral dengue in vitro. Methods: The method used is pure experimental research and the research design method is post test only control group design. The subject is dengue virus serotype 2 strain New GuineaC (DENV2 NGC) obtained from the Laboratory of Virology and Molecular Biology Department of Microbiology, Faculty of Medicine, University of Indonesiaand this research was started from June until November 2016. The independent variables in this study is the concentration of Jati Belanda leafs extracts obtained from Pharmaceutical Laboratory of Faculty Pharmacy, Gadjah Mada University and dependent variable are infectivity value and viability value. The collected data are presented in tables. Results:In concentration 40 g/ml, the infectivity value is 12.6% and the viability value is 91.4%. Conclusions: The leaf extracts of Jati Belanda is potentially effective as antiviral dengue. Keywords: dengue, Jati Belanda extract, antivirus, DHF
Co-Authors . Marwoto . Marwoto . Pudjiastuti . Pudjiastuti Arina Setyaningrum Aviaddina Ramadhani Dhani Redhono, Dhani Dio Dara Virgiansari Dwi Hidayah Dwi Hidayah Eko Setijanto Harsono Harsono Henrikus Jeffrey F .L Hutami Sri Ummiyati Maarif, Athok Shofiudin Marufah, Siti marwoto marwoto Maryani Maryani Mashuri, Yusuf Ari Mochammad Imron Awalludin Nawanindha, Natasha Pradiptakirana, Riska Pratiwi, Yani Dwi Putra, Lutfi Lafil Cahya Ratih Dewi Yudhani Ratih Puspita Febrinasari Reviono Reviono Rizka Solehah Sarah Luthfiani Sebayang, Pribadi M Sheilla Elfira San Pambayun Siti Marufah SURYAWATI, BETTY SURYAWATI, BETTY Suyatmi . Vitri Widyaningsih Yani Dwi Pratiwi Yulia Sari Yusup Subagio Sutanto