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All Journal Jurnal Rekayasa Sipil dan Desain Bisma: Jurnal Bisnis dan Manajemen JURNAL MANAJEMEN BISNIS Jurnal Respirologi Indonesia Jurnal Pengabdian Dharma Wacana JagoMIPA: Jurnal Pendidikan Matematika dan IPA Jurnal Pengabdian Masyarakat Journal of Artificial Intelligence and Digital Business
Fitri Indah Sari
Departemen Kesehatan Lingkungan Fakultas Kesehatan Masyarakat Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Mathematics Medicine & Pharmacology Physics Social Sciences Other

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KL-6 Serum Elevation among Supit Urang Landfill Workers: Based on Length of Work Duration and Type of Work Anggraeni, Rizki Diah; Astuti, Tri Wahju; Sari, Fitri Indah; Rakhma, Sastia
Jurnal Respirologi Indonesia Vol 46 No 2 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/57wdw018

Abstract

Background: KL-6 serum was a glycoprotein biomarker of lung inflammation and epithelial damage. Waste workers at Supit Urang Landfill, Malang, Indonesia has a risk from occupational inhalation exposure such as bacterial bioaerosol, VOC, CH4, CO, H2S. This study analyzed serum KL-6 serum levels as inflammation biomarker according to length of exposure duration and type of work. Methods: The study design analytic experimental with cross-sectional approached. Total subject was 79 worker who grouped by exposure duration in 24 subjects on 1–5 years; 29 subjects on 5–10 years; 26 subjects on >10 years as. Others groups type of work consisted of 48 scavengers; 20 waste sorters as; 9 waste processors; 2 laboratories technicians. KL-6 levels were measured by ELISA. Anova and spearman-rho analysis was used for KL-6 serum level in each group. Results: KL-6 serum level was significantly (p = 0.000) increased in workers with >10 years of exposure (1170,3 ± 621,4 U/mL) compared to the others group. Scavengers have a significantly (p = 0,002) increased of KL-6 serum level (1049,6 ± 586,6 U/mL) compared to the others groups. Moderate correlation existed between exposure duration and KL-6 serum levels with positive result (r=0.470, p=0.000). Conclusion: The research found higher serum KL-6 levels after 10 years of exposure. Gas product exposure puts scavengers at danger of inhalation.
Co-Authors Amin, Rois Anggraeni, Rizki Diah Dini, Zata Guntur, Dimas Imam Suroso Jusman, Ikhsan Amar Kamid, Kamid Lutfi, Andi Nur Alam Nurhayati Nurhayati Putra, Andius D. Rakhma, Sastia Rohani Rohani Samsul Bahri Sasmita, Halida Sulaiman, Asep Suradi, Purnawati Suryaman, Rachmat Syah, Aminudin Tri Wahju Astuti, Tri Wahju Yelli Ramalisa