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All Journal Journal of Food and Pharmaceutical Science Jurnal Sain Veteriner Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Journal of Food and Pharmaceutical Sciences
Erna Prawita Setyowati
Cancer Chemoprevention Research Center, Faculty Of Pharmacy, Universitas Gadjah Mada, Yogyakarta
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Veterinary

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Journal : INDONESIAN JOURNAL OF PHARMACY

 1 
The Properties of Brown Marine Algae Sargassum turbinarioides and Sargassum ilicifolium Collected From Yogyakarta, Indonesia Artemisia, Rahma; Nugroho, Akhmad Kharis; Setyowati, Erna Prawita; Martien, Ronny
Indonesian Journal of Pharmacy Vol 30 No 1, 2019
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1101.433 KB) | DOI: 10.14499/indonesianjpharm30iss1pp43

Abstract

Brown marine algae are the prominent source of marine natural products that have bioactive metabolites. Sargassum turbinarioides and Sargassum ilicifolium were dominated in Indonesia as brown marine algae that well known as a source of fucoidan. The samples were collected from Gunungkidul, Yogyakarta, Indonesia. In this study, we investigated and identified the yield of aqueous crude and purified extracts using different extraction temperatures (60°C, 70°C, 80°C, 90 °C). The highest yield of S. turbinarioides crude extract (7.36%) was obtained at temperatures 90 and 80 °C while the highest yield of S. ilicifolium was 3.49 % at 80 °C. The presence of sulfate polysaccharide in Sargassum turbinarioides is 3,78 % and Sargassum ilicifolium is 2,93 %. Each of the extract was screened using phytochemical detection, Thin Layer Chromatography (TLC) and Fourier transform infrared spectroscopy (FT-IR) analysis. The phytochemical detection indicated that Sargassum ilicifolium has bioactive metabolites such as carbohydrates, proteins and amino acids, terpenoid, phenolic compounds, and flavonoids. The FTIR spectrum of the S. turbinarioides and Sargassum ilicifolium extract refer to the presence of ester sulfate groups through showing  peaks at 1300 to 1200 cm-1 and 980 to 950 cm-1. The result indicated that Sargassum turbinarioides and Sargassum ilicifolium contain of sulfate polysaccharide were prospect a biological activities to use for the development of marine nutraceutical drugs especially as antioxidant.
Jaspamide: Structure identification of cytotoxic and fungicide compound isolated from Stylissa flabelliformis sponges Setyowati, Erna Prawita; ., Sudarsono; Wahyuono, Subagus
Indonesian Journal of Pharmacy Vol 16 No 1, 2005
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.597 KB) | DOI: 10.14499/indonesianjpharm0iss0pp12-19

Abstract

A research on the structure identification of cytotoxic and fungicide compound of Stylissa flabelliformis sponge has been conducted. The structure identification was analysed with spectroscopy ultraviolet, MS, 1HNMR and 13C-NMR methods.Based on the spectroscopic data and comparison with literatures, the compound was identified as jaspamide.Key words: sponge, Stylissa flabelliformis , jaspamide, structure elucidation
Co-Authors . Larasati ., Sudarsono Agung Budiyanto Agustina Dwi Wijayanti Akhmad Kharis Nugroho Artemisia, Rahma Astrid Ayu Maruti Edy Meiyanto Elisa Issusilaningtyas Fauzia Nur Laili, Fauzia Nur Fortunella Tjondro Hargiani, Fransisca Xaveria Isnindar Isnindar Naela Wanda Yusria Dalimunthe Pertiwi, Ratih Dyah Raditya Prima Istiaji Rima Yulia Senja, Rima Yulia Ronny Martien Ronny Martien Sri Wahdaningsih Subagus Wahyuono Susi Iravati Suwaldi . Wahyuono, Subagus