Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana Nusantara Medical Science Journal Majalah Anestesia dan Critical Care Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) JKMM Majalah Anestesia & Critical Care (MACC) Jurnal Penyakit Dalam Indonesia
Arifin Seweng
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Platelet Limphocyte Ratio and Procalcitonin in Survivor and Non-Survivor Sepsis Patients at Dr. Wahidin Sudirohusodo Hospital Makassar Fitriana, Astri Yul; Nurulita, Asvin; Bahrun, Uleng; Arifin Seweng
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2396

Abstract

 Sepsis is a life-threatening organ dysfunction caused by dysregulation in the host's response to infection and is a major cause of global morbidity and mortality.The platelet-to-lymphocyte ratio (PLR) is considered a prognostic marker of sepsis. Another inflammatory marker, procalciton in which is secreted in response to bacterial endotoxin can also serve as a biomarker for diagnosis, prognosis and monitoring of sepsis patients. Analysis of platelet lymphocyte ratio and procalcitonin levels may therefore be useful for predicting survival outcomes in sepsis. This retrospective observational study included 276 patients diagnosed with sepsis, consisting of 128 survivors and 148 non-survivors. Statistical analysis was performed using the Kolmogorov-Smirnov test, Mann-Whitney test, Spearman correlation test, and Friedman test, with significance defined as p <0.05. No significant differences in mean platelet-to lymphocyte ratio between a survivors and non-survivors on day 1 (200.59 vs 233.91, p >0.05), day 3 (191.58 vs 238.74, p >0.05), or day 5 (210.42 vs 208.62, p >0.05). Similarly, no significant difference in mean procalcitonin levels was found on day 1 (20.18 ng/mL vs 16.20 ng/mL, p >0.05). However, mean procalcitonin levels were significantly lower in survivors compared with non-survivors on day 3 (14.04 ng/mL vs 17.48 ng/mL, p <0.05) and day 5 (7.78 ng/mL vs 23.06 ng/mL, p <0.05). In survivors, procalcitonin levels showed a significant decreasing trend across days 1, 3, and 5 (p <0.05). There was no difference in platelet-to-lymphocyte ratio values between survivors and non-survivors. There was a significant difference in procalcitonin levels between survivors and non-survivors on the third and fifth days.
Co-Authors , Masrianil A.A. Ketut Agung Cahyawan W Adil, Andi Amiruddin L Andi Arsunan Arsin Andi Mardiah Tahir Ariany Asnur Arief, Erwin Arif, Syafri K. Asvin nurulita, Asvin Bachtiar Murtala Darmawansyah Darmawansyah Darmayanti Waluyo Elis Daniar Barunawati Fadilah Fadilah Fitriana, Astri Yul Healthy Hidayanty Hisbullah Jeri J Latief, Nikmatia Mochammad Riyadi Muh. Alwy Arifin Muhammad Ramli Ahmad Nurdin, Haizah Nurlaily Idris Nu’man As Daud Salahuddin, Andi Sri Asriyani Sri Hertati Endang SRI RAHAYU Syafruddin Gaus Tabri, Nur Ahmad Takdir, Andi Khomeini Uleng Bahrun, Uleng