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All Journal Disease Prevention and Public Health Journal Jurnal Kesehatan Andalas Majalah Farmaseutik Media Ilmu Kesehatan JSFK (Jurnal Sains Farmasi & Klinis) JPSCR : Journal of Pharmaceutical Science and Clinical Research JFIOnline Pharmaceutical Journal of Indonesia Majalah Farmasetika Abdimasku : Jurnal Pengabdian Masyarakat Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Journal of Innovation in Community Empowerment (JICE) Jurnal Farmasi Indonesia Acta Holistica Pharmaciana Journal of Pharmaceutical (JOP)
Padmasari, Siwi
Program Studi Farmasi, Fakultas Kesehatan, Universitas Jenderal Achmad Yani Yogyakarta
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Gambaran Drug Related Problems (DRPs) Terapi Farmakologi Pasien ISPA Pediatrik di Rumah Sakit PKU Muhammadiyah Gamping Yogyakarta Husna, Nadia; Padmasari, Siwi
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1790

Abstract

Acute Respiratory Infection has become the major cause of death in children in developing countries. There were about 11.9 million episodes of severe acute lower respiratory infection that resulted in hospital admission in young children worldwide. The method of drug administered was the common Drug-Related Problems found in young children. Objectives: To evaluated Drug-Related Problems of Acute Respiratory Infection drug therapy in pediatric patients. Methods: Ninety-four pediatric patients were included in this study. Drug therapy data were obtained from medical records from January 2018 until July 2019, as this study was using a retrospective method. Drug-Related Problems of drug therapy were analyzed based on the Cipolle classification system. Results: Prevalence of female and male patients are in the same number (50%) with the highest prevalence on 2-11 years (72.34%) in young children. The number of Drug-Related Problems was found about 61.49% from 148 numbers of used drugs with improper drug selection as the major Drug Related Problems (51,65%)  followed by drugs without indication and underdose by 23.08% and 15.38%, respectively.Keywords:  acute respiratory infection, hospital, pediatrics, pharmacologic therapy
Hubungan Interaksi Obat Antidiabetik Dengan Luaran Klinik Pada Pasien DM Tipe 2 Rawat Inap di RS PKU Muhammadiyah Gamping Yogyakarta Sugiyono, Sugiyono; Padmasari, Siwi; Al Madury, Shalahuddin
MEDIA ILMU KESEHATAN Vol 14 No 1 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v14i1.1479

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic disease that often requires combination therapy, increasing the risk of drug interactions due to polypharmacy, which can affect clinical outcomes. Objective: To examine the relationship between the potential for drug interactions and clinical outcomes in hospitalized T2DM patients at PKU Muhammadiyah Gamping Hospital, Yogyakarta, from January 2022 to August 2023. Methods: This study employed a non-experimental analytical method with a retrospective approach, involving 179 patients who met the inclusion criteria. Univariate analysis was used to describe patient characteristics, medication patterns, and Random Blood Glucose (RBG) levels, while bivariate analysis (Chi-Square test) assessed the relationship between the potential for drug interactions and clinical outcomes.Results: The majority of T2DM patients were aged 41-59 years (50.28%), female (54.75%), and had comorbidities (91.62%). The most common treatment regimen was monotherapy with metformin (46.37%). Most patients received ≥5 medications (88.27%), and 81.56% had potential drug interactions. The predominant interaction mechanism was pharmacodynamic (86.21%) with moderate severity (89.72%). Chi-Square analysis yielded a p-value of 0.082 (p>0.05).Conclusion: No significant relationship was found between the potential for antidiabetic drug interactions and clinical outcomes in patients
Co-Authors Adinda Fitriani Al Madury, Shalahuddin Azizah, Fajriyati Nur Fajriyati Nur Azizah Febriyani, Ghesa Hidayanti, Puri Hidayanti, Puri Husna, Nadia Ishak Ishak Laim, Lidya Adriana Clarita Lestari, Mardiana Puji Marchaban Maria Lisa Nova Mukharomah Zaitin Nadia Husna Niken Larasati Niken Larasati Ningsih, Endang S Ningsih, Endang S Pangestika, Annisa Prayoga, Sigit Rahma Alfi Saadati Saadati, Rahma Alfi Saepudin, . Setiawati, Margarita Krishna Shalahuddin Al Madury, Shalahuddin Al Sigit Prayoga Sugiyono Sugiyono Sugiyono Zaitin, Mukharomah