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All Journal Global Health Management Journal QARDHUL HASAN: MEDIA PENGABDIAN KEPADA MASYARAKAT Manuju : Malahayati Nursing Journal Jambura Journal of Health Sciences and Research PREPOTIF : Jurnal Kesehatan Masyarakat Tunas Medika Jurnal Kedokteran & Kesehatan Indonesian Journal of Applied Research (IJAR) JPM: JURNAL PENGABDIAN MASYARAKAT PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat KOLONI InaBHS (Indonesian Journal of Biomedicine and Health Science) Jurnal Pengabdian Masyarakat Inovasi Indonesia
Rama Samara Brajawikalpa
Universitas Swadaya Gunung Jati
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation Other

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Edukasi Pemanfaatan Tanaman Herbal Berbasis Literasi Kesehatan dalam Pengembangan Wisata Kampung Herbal Ismail Saleh; Umi Trisnaningsih; Rama Samara Brajawikalpa
Qardhul Hasan: Media Pengabdian kepada Masyarakat Vol. 12 No. 1 (2026): Qardhul Hasan: Media Pengabdian kepada Masyarakat
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/qh.v12i1.22998

Abstract

Desa Bantaragung merupakan desa wisata unggulan yang memiliki potensi biodiversitas herbal melimpah, namun belum teroptimasi sebagai daa tarik eduwisata. Selain itu, terdapat masalah rendahnya literasi kesehatan masyarakat, di mana hasil pre-test menunjukkan 100% responden menganggap herbal sebagai pengganti total obat kimia tanpa risiko. Kegiatan pengabdian ini bertujuan untuk mengembangkan destinasi "Kampung Herbal" sekaligus meningkatkan literasi penggunaan herbal yang rasional bagi Pokdarwis dan warga Blok Gibug. Metode yang digunakan adalah Participatory Action yang meliputi sosialisasi berbasis pre-post test, pelatihan budidaya, serta penataan lahan eduwisata. Hasil pengabdian menunjukkan adanya peningkatan pengetahuan yang signifikan, terutama pada aspek keamanan herbal bagi kelompok rentan yang meningkat tajam dari 25% menjadi 93%. Secara fisik, telah terbentuk jalur Kampung Herbal yang dilengkapi media informasi. Peningkatan literasi ini tidak hanya berhasil meluruskan miskonsepsi kesehatan di masyarakat, tetapi juga menjadi nilai tambah strategis dalam memperkuat posisi Desa Bantaragung sebagai destinasi agro-eduwisata yang aman, edukatif, dan berkelanjutan bagi wisatawan.
Antibacterial Activity of Mango Gedong Gincu Peel Fraction in Inhibiting the Growth of Staphylococcus aureus Rama Samara Brajawikalpa; Robi'atul 'Adawiyah
Indonesian Journal of Applied Research (IJAR) Vol. 6 No. 3 (2025): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v6i3.773

Abstract

Gedong Gincu Mango peel (Mangifera indica L.) contains a variety of secondary metabolites, including flavonoids, tannins, saponins, alkaloids, and terpenoids. These compounds play a crucial role in self-defence and exhibit significant pharmacological activity, particularly as antibacterial agents. The purpose of this study is to identify the content of secondary metabolite compounds of each fraction based on its polarity properties, and to determine the inhibitory power of Staphylococcus aureus ATCC 25293 bacteria. This study is experimental research with a post-test only control group. This study used 2 control groups and 12 treatment groups consisting of n-hexane, ethyl acetate, and butanol fractions with concentrations of 6.25%, 12.5%, 25%, 50% respectively and repeated 3 times. The antibacterial test was carried out by the well diffusion method, which was repeated 3 times on the MHA medium, and the inhibition zone was measured. The study showed that the n-hexane fraction contained alkaloids, steroids, and saponins, while the ethyl acetate and butanol fractions contained flavonoids, alkaloids, tannins, triterpenoids, and phenolics. A 50% concentration produced the greatest inhibition zone in all fractions, with mean values of 8.05 mm (moderate) for n-hexane, 15.41 mm (strong) for ethyl acetate, and 12.16 mm (strong) for butanol. The 50% ethyl acetate fraction was the most effective in inhibiting the growth of Staphylococcus aureus ATCC 25923.
Pengaruh Pemberian Ekstrak Daging Buah Mangga (Mangifera Indica.L) Varietas Gedong Gincu Terhadap Kadar Asam Urat Tikus Putih Jantan yang Dibuat Hiperurisemia Rama Samara Brajawikalpa; Menik Herdwiyanti; Sri Marfuati; Esa Giri Rahayu; Amalia Dwi Ayu Pitaloka; Arthur Ulil Albab
Malahayati Nursing Journal Vol 6, No 3 (2024): Volume 6 Nomor 3 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i3.12939

Abstract

ABSTRACT Indonesia has produced many new herbal medicines made from natural ingredients. One of them is the Mango (Mangifera indica L.) gedong gincu variety which has unique phytochemical content including high levels of vitamin C, flavonoids and antioxidants. Flavonoids are known to inhibit xanthine oxidase so they can be used as an alternative treatment for gout.  To analyze the effect of administering gedong gincu variety mango (Mangifera indica L.) extract on the uric acid levels of white rats that cause hyperuricemia.  This is experimental study with pre and post test research design and control group. using 25 male white rats (Rattus norvegicus) Sprague Dawley strain divided into 5 groups, as normal control group (KK1), positive control (KK2), control and 3 experimental groups (KP) received gedong gincu mango pulp extract with doses of 75, 150, and 300 mg/200grBW rats. The data was tested using a One way ANOVA and Post Hoc. There was a statistical difference between before and after being given gedong gincu mango extract from KP 1, KP 2, and KP 3 (p0.05) and a decrease in uric acid levels (p0.05) of 3.83, 4.084, and 4.248 mg/dl. Conclusion: There was a significant difference in the uric acid levels of the treatment groups, where gedong gincu mango peel extract at a dose of 300mg/200grBB had the most effective results compared to other doses. Keywords: Hyperuricemia, Mangifera Indica L, Extract of Gedong Gincu Mango Flesh  ABSTRAK Indonesia banyak melahirkan obat-obat herbal baru yang berbahan dasar dari alam. Salah satunya adalah Mangga (Mangifera indica L.) varietas gedong gincu yang memiliki kandungan fitokimia yang khas diantaranya, kandungan vitamin C, flavonoid dan antioksidan yang tinggi tinggi. Flavonoid diketahui dapat menghambat xantin oksidase sehingga dapat dijadikan sebagai alternatif pengobatan pada penyakit asam urat. Menganalisis pengaruh pemberian ekstrak buah mangga (Mangifera indica L.) varietas gedong gincu terhadap kadar asam urat tikus putih yang dibuat hiperurisemia. Penelitian ini bersifat eksperimental dengan rancangan penelitian pre and post test with control group design dengan menggunakan 25 tikus Putih (Rattus norvegicus) jantan galur Sprague dawley yang dibagi menjadi 5 kelompok, yaitu kelompok kontrol normal (KK1), kontrol positif (KK2), dan 3 kelompok perlakuan (KP) yang mendapat ekstrak daging buah mangga gedong gincu dengan dosis bertingkat 75, 150, dan 300 mg/200grBB tikus. Data diuji menggunakan uji one-way ANOVA dan post hoc. Terdapat perbedaan antara sebelum dan sesudah diberikan ekstrak buah mangga gedong gincu dari KP 1, KP 2, dan KP 3 secara statistik (p0,05) dan penurunan kadar asam urat (p0,05) sebesar 3,83, 4,084, dan 4,248 mg/dl. Terdapat perbedaan bermakna dari kadar asam urat kelompok perlakuan, dimana ekstrak kulit buah mangga gedong gincu dosis 300mg/200grBB memiliki hasil yang paling efektif dibandingkan dengan dosis lainnya. Kata Kunci: Hiperurisemia, Mangifera Indica L, Ekstrak Daging Buah Mangga Gedong Gincu
Hubungan Kepatuhan Terapi terhadap Lesi Kulit dan Kualitas Hidup Pasien Dermatitis Atopik di Rumah Sakit Umum Daerah Waled Kabupaten Cirebon Aurora Nurfauziyyah Nabiilah Fatimatuzah; Rama Samara Brajawikalpa; Yukke Nilla Permata
Malahayati Nursing Journal Vol 8, No 2 (2026): Volume 8 Nomor 2 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v8i2.22213

Abstract

ABSTRACT Atopic dermatitis is a chronic relapsing condition that requires long-term therapy. Therefore, treatment success greatly depends on the patient’s adherence to therapy in order to prevent recurrence and improve quality of life. To assess the correlation between treatment adherence, skin lesion severity, and quality of life in patients with atopic dermatitis at Waled Regional General Hospital, Cirebon Regency. This was an analytical observational study with a cross-sectional design. Participants were patients aged 17–65 years who met the inclusion criteria. Data were collected using a treatment adherence questionnaire, the Dermatology Life Quality Index (DLQI), and the SCORAD index to assess lesion severity. Spearman’s rank correlation test was used to analyze the relationships between variables. A significant negative correlation was found between treatment adherence and lesion severity p 0,000 r = -0,580, as well as between adherence and quality of life p 0,000 r = -0,793. Treatment adherence is significantly associated with reduced lesion severity and improved quality of life in patients with atopic dermatitis. Educational interventions and continuous adherence monitoring are essential in the management of this chronic condition. Keywords: Atopic Dermatitis, Treatment Adherence, Skin Lesions, Quality of Life, SCORAD, DLQI.  ABSTRAK Dermatitis atopik memiliki karakteristik penyakit kronis residif yang memerlukan terapi jangka panjang sehingga keberhasilan terapi sangat ditentukan oleh tingkat kepatuhan pasien dalam menjalani pengobatan untuk mencegah kekambuhan dan peningkatan kualitas hidup. Mengetahui hubungan antara kepatuhan terapi dengan lesi kulit dan kualitas hidup pasien dermatitis atopik di RSUD Waled, Kabupaten Cirebon. Penelitian observasional analitik dengan pendekatan cross-sectional. Subjek penelitian adalah pasien dermatitis atopik berusia 17–65 tahun yang memenuhi kriteria inklusi. Data diperoleh melalui kuesioner kepatuhan, instrumen Dermatology Life Quality Index (DLQI), dan penilaian keparahan lesi menggunakan skor SCORAD. Hubungan antar variabel dianalisis menggunakan uji korelasi Rank Spearman. Terdapat hubungan yang signifikan antara kepatuhan terapi dan lesi kulit dengan nilai p = 0,000 dan r = -0,580. Selain itu, terdapat korelasi yang signifikan antara kepatuhan terapi dan kualitas hidup dengan nilai p = 0,000 dan r = -0,793. Terdapat hubungan signifikan antara kepatuhan terapi dengan lesi kulit dan peningkatan kualitas hidup pasien dermatitis atopik. Intervensi edukatif dan monitoring kepatuhan terapi diperlukan dalam manajemen penyakit ini.                                                                                          Kata Kunci: Dermatitis Atopik, Kepatuhan Terapi, Lesi Kulit, Kualitas Hidup, SCORAD, DLQI.
Pola Penggunaan Antibiotik pada Pasien Demam Tifoid di Instalasi Rawat Inap Rsud Waled Tahun 2023 Bagas Dharma Utama; Sri Marfuati; Rama Samara Brajawikalpa
KOLONI Vol. 5 No. 2 (2026): JUNI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i2.828

Abstract

Typhoid fever remains a significant public health problem in developing countries, including Indonesia, with high morbidity rates. Antibiotics are the main therapy for typhoid fever; however, irrational use may lead to antimicrobial resistance, increased treatment costs, and adverse effects. Therefore, evaluating the pattern of antibiotic use is essential to ensure rational therapy and improve patient outcomes. This study aimed to determine the pattern of antibiotic use among typhoid fever patients in the inpatient installation of RSUD Waled in 2023.This study employed a descriptive observational design with a retrospective approach using medical record data. A total sampling technique was applied, resulting in 88 patients who met the inclusion criteria. Variables observed included patient characteristics, types of antibiotics, dosage forms, duration of use, side effects, and allergic responses.The results showed that all patients were confirmed cases (100%), with the majority aged 6–11 years (40.9%) and predominantly male (51.1%). Most patients used BPJS health insurance (96.6%). Cephalosporins were the most frequently prescribed antibiotics (88.6%), mainly administered in parenteral form (77.3%). All patients received antibiotic therapy with appropriate duration according to guidelines (100%), and no side effects or allergic reactions were reported (100%). In conclusion, the pattern of antibiotic use in typhoid fever patients at RSUD Waled in 2023 was consistent with clinical guidelines, dominated by cephalosporin use, and showed no adverse effects or allergic reactions. These findings are important to support rational antibiotic use and to prevent the development of antimicrobial resistance.*
Effect of Ethyl Acetate Fraction of Avocado Peel (Persea americana Mill.) on Total Cholesterol Levels in Hypercholesterolemic Wistar Rats Ferdian Adhy Pratama Putra; Ignatius Hapsoro Wisandoko; Rama Samara Brajawikalpa
GHMJ (Global Health Management Journal) Vol. 8 No. 3 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-831158

Abstract

Background: Hypercholesterolemia is a condition that can increase the risk of coronary heart disease, stroke, high blood pressure, obesity and other health problems. The ethyl acetate fraction of avocado peel offers a novel approach by isolating key bioactive compounds while separating them from other components, focusing on the desired properties of compounds such as flavonoids, saponins, and phenolics, which are well-known for their antihyperlipidemic effects. Aims: To analyze the effect of ethyl acetate fraction of avocado peel (Persea americana Mill.) on total cholesterol levels of Wistar white rats with hypercholesterolemia. Methods: This study was experimental with a pre and post test with control group design using 20 male white rats (Rattus norvegicus) of the Wistar strain that had been fed high-fat feed for 14 days and divided into 5 groups for 7 days of treatment, namely the negative control group that was given only high-fat feed, the positive control group that was given the drug simvastatin 0.18 mg/200gBW, and 3 treatment groups that were given the ethyl acetate fraction of avocado peel with a tiered dose of 100 mg/KgBW,  75 mg/KgBW, and 50 mg/kgBW. The data were analyzed using a one-way ANOVA test with a post hoc test Results: The ethyl acetate fraction of avocado fruit peel positively contains alkaloids, flavonoids, phenolics, saponins, tannins, and triterpenoids or steroids. The average reduction in total cholesterol levels is 19.5 mg/dL (p < 0.05) at a dose of 100 mg/kgBW, 17.5 mg/dL (p < 0.05) at a dose of 75 mg/kgBW, and 13 mg/dL (p < 0.05) at a dose of 50 mg/kgBW. Conclusion: The ethyl acetate fraction of avocado peel is effective in reducing total cholesterol levels with an effective dose of 100 mg/kgBW. With an effective dose of 100 mg/kg body weight that has been established, subsequent research can focus on the development of more stable and efficient formulations for clinical applications. The effect of lowering cholesterol levels is associated with the content of secondary metabolite compounds contained in the ethyl acetate fraction of avocado peels, namely flavonoids, phenolics, saponins, tannins, triterpenoids and steroids.
Co-Authors Aditya Naufal Ramzy Amalia Dwi Ayu Pitaloka Amanah Amanah Apriyanto, Dadan Ramadhan Arthur Ulil Albab Aurora Nurfauziyyah Nabiilah Fatimatuzah Ayudithiya, Vhirna Fitri Azizah B, Nur Alma Azizah, Hana Bagas Dharma Utama Beti Ernawati Dewi Catur Setiya Sulistiyana Cindyyani Eka Putri Dadan Ramadhan Apriyanto Diah Safitri Diah Safitri Emallia Fitriani Esa Giri Rahayu Ferdian Adhy Pratama Putra Ignatius Hapsoro Wisandoko Ismail Saleh Istiharah, Sherin Nadia Maelina, Maelina Marfuati, Sri Menik Herdwiyanti Mirella Gresyalli Kautama Mulyaningsih, Ruri Eka Maryam Nasution, Aulia Ananta Nia Hernanti Novianti Dwi Puspitasari Nugraha, Prendy Prasetya Nurdianti, Helma Nuria Nirmala Pahmi Budiman S. Basyir Pamungkas, Try Yogi Damar Raden Mohamad Herdian Bhakti Rayasari, Husnaya Ricardi Wicaksono Alibasjah Risnandya Primanagara Robi'atul 'Adawiyah Ruri Eka Maryam Mulyaningsih Siskanti, Alvina Sri Marfuati Umi Trisnaningsih Waly, Tuswandi Ahmad Weni, Mustika Yukke Nilla Permata Yulianti, Selsa ‘Adawiyah, Robi’atul